132,447 research outputs found

    Sharp, T. Robert, D.O.

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    A strong TCOM supporter, Dr. Sharp is the benefactor of the Sharp Award for Student Practitioner of the Year, presented annually since the first graduation in 1974. He served as chairman of the scholarship and loan committee for several years. Interviewed by C. Ray Stokes, October 20, 198

    Ross Jackson, a freemason covered in tattoos standing in the kitchen at the Northbridge Masonic Centre, Sydney, 15 May 2010 [picture] /

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    Title from acquisitions documentation, see file NLA10/2405.; Part of the collection: Freemasons in New South Wales, 2010.; Acquired in digital format; access copy available online.; Mode of access: Internet via World Wide Web.; Purchased from the photographer, 2010. "Ross Jackson, a freemason, is photographed in the kitchen at the Northbridge Masonic Centre, Sydney on 15th May 2010 at 4.30pm. The occasion is the reconsecration of the Lodge Highway for bikers. He and his family have been Freemasons for generations. His tattoos include a number of Freemasonry symbols, the T square and compass on his left arm and all seeing eye on his right arm"--Information supplied by photographer

    Physiological sharp wave-ripples and interictal events in vitro: What’s the difference?

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    Sharp wave-ripples and interictal events are physiological and pathological forms of transient high activity in the hippocampus with similar features. Sharp wave-ripples have been shown to be essential in memory consolidation, while epileptiform (interictal) events are thought to be damaging. It is essential to grasp the difference between physiological sharp wave-ripples and pathological interictal events in order to understand the failure of control mechanisms in the latter case. We investigated the dynamics of activity generated intrinsically in the CA3 region of the mouse hippocampus in vitro, using four different types of intervention to induce epiletiform activity. As a result, sharp wave-ripples spontaneously occurring in CA3 disappeared, and following an asynchronous transitory phase, activity reorganized into a new form of pathological synchrony. During epileptiform events, all neurons increased their firing rate compared to sharp wave-ripples. Different cell types showed complementary firing: parvalbumin-positive basket cells and some axo-axonic cells stopped firing due to a depolarization block at the climax of the events in high potassium, 4-aminopyridine and zero magnesium models, but not in the gabazine model. In contrast, pyramidal cells started firing maximally at this stage. To understand the underlying mechanism we measured changes of intrinsic neuronal and transmission parameters in the high potassium model. We found that the cellular excitability increased and excitatory transmission was enhanced, whereas inhibitory transmission was compromised. We observed a strong short-term depression in parvalbumin-positive basket cell to pyramidal cell transmission. Thus, the collapse of pyramidal cell perisomatic inhibition appears to be a crucial factor in the emergence of epileptiform events

    Sharp, R T, WX10001

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    This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/416287Surname: SHARP. Given Name(s) or Initials: R T. Military Service Number or Last Known Location: WX10001. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 44440.238440 Item: [2016.0049.48548] "Sharp, R T, WX10001

    Sharp, W. T. (SC 2627)

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    Finding aid only for Manuscripts Small Collection 2627. Letter of W. T. Sharp, Foster (Bracken County) Kentucky, to an unidentifed young lady. In the company of her sister, Mrs. Tegard, she had recently visited the store of H. S. Pribble & Company, where Sharp worked, and he asks permission to correspond with her

    Accurate Sharp Interface Scheme for Multimaterials

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    We present a method to capture the evolution of a contact discontinuity separating two different material. A locally non-conservative scheme allows an accurate and stable simulation while the interface is kept sharp. Numerical illustrations include problems involving fluid and elastic problems

    Letter, [Author unclear] to Paulina T. Merritt

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    Handwritten letter to Paulina Merritt from an unknown author, October 1, 1876.

    1963 -- Correspondence, Unsorted -- letter, 1966-06-02

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    Letter from Sharp, John T. to Sabin, Albert B. dated 1966-06-02.Sabin Collection Fair Use Policy</a

    1965, Jan.-June -- Correspondence, Unsorted -- letter, 1965-03-04

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    Letter from Sharp, John T. to Sabin, Albert B. dated 1965-03-04.Sabin Collection Fair Use Policy</a
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