39 research outputs found

    Designing for rehabilitation at home

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    New technologies open up possibilities for designing interactive experiences that can engage and motivate post-stroke survivors to undertake what would otherwise be boring repetitive movements. In this paper we outline a few of the challenges we met as part of the cross-disciplinary Motivating Mobility project. These are: the extended ‘user’; autonomy and motivation; and early prototype studies

    ON THE DISCOVERY OF A LARGE MICROBIAL COMMUNITY LIVING IN THE SOFT BOTTOMS OF THE CONTINENTAL SHELF OFF CHILE AND PERU

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    In a benthic macrofaunal survey of the continental shelf of northern Chile a peculiar filamentous material was collected in grab and dredge samples of greenish, foul smelling sediment from depths of 50 to 280 m (ref. 1). In reporting the results emphasis was placed, however, on the fact that a virtually iazoic* bottom had beenfound between depths of 50 to 400 m. Average biomass was only 0.17 g (wet weight) /m2 , with 6.6 individuals /m2*. The distribution of the azoic sediments coincided with low oxygen concentrations in the water above (ref. 2). The author again found white filamentous material while sampling the benthos off the Bay of Concepcion and the Gulf of Arauco, in central Chile. These findings together with the casual observation of filaments in the mouth parts of the commercially important galatheid shrimp Pleuroncodes mondon, initiated new efforts to learn about this material and its possible ecological significance.</jats:p

    A single journal study : Malaysian Journal of Computer Science

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    Single journal studies are reviewed and measures used in the studies are highlighted. The following quantitative measures are used to study 272 articles published in Malaysian Journal of Computer Science, (1) the article productivity of the journal from 1985 to 2007, (2) the observed and expected authorship productivity tested using Lotka's Law of author productivity, identification and listing of core authors; (3) the authorship, co-authorship pattern by authors' country of origin and institutional affiliations; (4) the subject areas of research; (5) the citation analysis of resources referenced as well as the age and half-life of citations; the journals referenced and tested for zonal distribution using Bradford's law of journal scattering; the extent of web citations; and (6) the citations received by articles published in MJCS and impact factor of the journal based on information obtained from Google Scholar, the level of author and journal self-citation

    Estructura poblacional de Pinus radiata D.Don en fragmentos de Bosque Maulino en Chile central

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    Gomez, P (reprint author), Univ Talca, Jardin Bot, Casilla 747, Talca, Chile.Gomez, P (Gomez, Persy); Bustamante, R (Bustamante, Ramiro); San Martin, J (San Martin, Jose); Hahn, S (Hahn, Steffen)In this note we examine the population structure of Pinus radiata, exotic plant that is invading fragments of the Maulino Forest. We evaluate pine density, age, proportion of reproductive individuals across 8 forest fragments. Our results indicate a high proportion of young individuals and reproductive individuals growing inside fragments. Moreover, the fragment size is negatively correlated with pine density but, the proportion of reproductive individuals are not correlated with this landscape attribute. Our result indicate the existence of a pine population that is actively invading forest fragments, a fact that needs to be considered in conservation plans of this native forest

    Comparación de fórmulas chilenas e internacionales para valorar el arbolado urbano

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    Ponce-Donoso, M (reprint author), Univ Talca, Fac Ciencias Forestales, Casilla 747, Talca, Chile.The appraisal of urban trees is a practice adopted in diverse cities of world. This survey compared international formulae: Council of Tree Landscape Appraiser (CTLA), Burnley, Helliwell and Standard Tree Evaluation Method (STEM) and three Chilean methods applied in municipalities of Concepcion, La Pintana, Maip (COPIMA), Nunoa and Penalolen, in 14 different trees located in Talca city (Chile). The objective was to identify the differences and similarities of the monetary result in the application of these formulae, which was realized by a professional. These were analyzed using a non parametric variance test of Kruskal - Wallis and the multiple comparisons Duncan test. It was possible to determine that the Chilean formulae did not present statistically significant differences with the international formulae of Burnley and CTLA; whereas Penalolen and COPIMA formulae did not present any difference when contrasted with Helliwell. In addition, the STEM formula presented differences with all the Chilean analyzed formulae. In the valuation by tree, statistically significant differences were obtained, which showed the independence of the used formula. The exception was when being applied to emblematic species or to species that stand-out in some amenity. Likewise, it was observed that the basic value continues having a high impact in the appraisal final result and the use of the statistical test applied allows extending this type of analyses

    Extended pancreas donor program - the EXPAND study rationale and study protocol

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    BACKGROUND: Simultaneous pancreas kidney transplantation (SPK), pancreas transplantation alone (PTA) or pancreas transplantation after kidney (PAK) are the only curative treatment options for patients with type 1 (juvenile) diabetes mellitus with or without impaired renal function. Unfortunately, transplant waiting lists for this indication are increasing because the current organ acceptability criteria are restrictive; morbidity and mortality significantly increase with time on the waitlist. Currently, only pancreas organs from donors younger than 50 years of age and with a body mass index (BMI) less than 30 are allocated for transplantation in the Eurotransplant (ET) area. To address this issue we designed a study to increase the available donor pool for these patients. METHODS/DESIGN: This study is a prospective, multicenter (20 German centers), single blinded, non-randomized, two armed trial comparing outcome after SPK, PTA or PAK between organs with the currently allowed donor criteria versus selected organs from donors with extended criteria. Extended donor criteria are defined as organs procured from donors with a BMI of 30 to 34 or a donor age between 50 and 60 years. Immunosuppression is generally standardized using induction therapy with Myfortic, tacrolimus and low dose steroids. In principle, all patients on the waitlist for primary SPK, PTA or PAK are eligible for the clinical trial when they consent to possibly receiving an extended donor criteria organ. Patients receiving an organ meeting the current standard criteria for pancreas allocation (control arm) are compared to those receiving extended criteria organ (study arm); patients are blinded for a follow-up period of one year. The combined primary endpoint is survival of the pancreas allograft and pancreas allograft function after three months, as an early relevant outcome parameter for pancreas transplantation. DISCUSSION: The EXPAND Study has been initiated to investigate the hypothesis that locally allocated extended criteria organs can be transplanted with similar results compared to the currently allowed standard ET organ allocation. If our study shows a favorable comparison to standard organ allocation criteria, the morbidity and mortality for patients waiting for transplantation could be reduced in the future. TRIAL REGISTRATION: Trial registered at: NCT0138400

    Relationship among research collaboration, number of documents and number of citations. A case study in Spanish computer science production in 2000-2009.

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    This paper analyzes the relationship among research collaboration, number of documents and number of citations of computer science research activity. It analyzes the number of documents and citations and how they vary by number of authors. They are also analyzed (according to author set cardinality) under different circumstances, that is, when documents are written in different types of collaboration, when documents are published in different document types, when documents are published in different computer science subdisciplines, and, finally, when documents are published by journals with different impact factor quartiles. To investigate the above relationships, this paper analyzes the publications listed in the Web of Science and produced by active Spanish university professors between 2000 and 2009, working in the computer science field. Analyzing all documents, we show that the highest percentage of documents are published by three authors, whereas single-authored documents account for the lowest percentage. By number of citations, there is no positive association between the author cardinality and citation impact. Statistical tests show that documents written by two authors receive more citations per document and year than documents published by more authors. In contrast, results do not show statistically significant differences between documents published by two authors and one author. The research findings suggest that international collaboration results on average in publications with higher citation rates than national and institutional collaborations. We also find differences regarding citation rates between journals and conferences, across different computer science subdisciplines and journal quartiles as expected. Finally, our impression is that the collaborative level (number of authors per document) will increase in the coming years, and documents published by three or four authors will be the trend in computer science literature

    Unraveling the conglomeratic nature of methanol clusters adsorbed on graphene surfaces. Insights from molecular dynamics simulations

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    The expression of chirality in adsorption phenomena constitutes an important topic, not only relevant to asymmetric transformations involving solid surfaces, but also to the emergence of homochirality in both terrestrial and extraterrestrial scenarios. Methanol (MeOH) aggregation on graphite/graphene, one of the most idealized adsorbate–adsorbent systems, leads to islands of cyclic clusters of different sizes (Nano Lett., 2016, 16, 3142–3147). Here, we show that this aggregation occurs enantioselectively affording 2D conglomerates depending on the size of clusters, in close analogy to a Pasteurian racemate. Homochiral sequences are held together by hydrogen bonding and other non-covalent interactions, whose absolute configurations can be appropriately specified. A discussion involving the dichotomy between 2D racemates and conglomerates, is offered as well. In addition, the present simulations showcase a broad range of acyclic and cyclic structures, even if some discrete rings are the dominant species, in agreement with previous experimental data and theoretical modeling. Our results indicate that MeOH clusters show binding energies close to the experimental values, remaining intact at temperatures as high as 120 K and up to 150 K.J. G.-C and I. J.-S. acknowledge funding from grant PID2022136814NB-I00 funded by the Spanish Ministry of Science, Innovation and Universities/State Agency of Research MICIU/ AEI/10.13039/501100011033 and by “ERDF/EU”. I. J.-S. acknowledges support from the ERC grant OPENS (project number 101125858) funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reect those of the European Union or the European Research Council Executive Agency. Neither the European Union nor the granting authority can be held responsible for them. Computational resources were provided by CENITS and Foundation Computaex through the HighPerformance Computing facility LUSITANIA-II, which are greatly appreciated. We would like express gratitude to Prof. Laurence Barron for whole-hearted discussions on molecular chirality.Peer reviewe

    Eventos adversos relacionados a la vacunación contra sars-cov-2 en Córdoba, Colombia

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    La seguridad de la vacuna contra SARS-CoV-2 ha sido una de las preocupaciones que ha dejado la pandemia del coronavirus en el mundo debido a múltiples reacciones clínicas que se presentaron en pacientes a quienes les fue administrada este tipo de agentes para contener el impacto de la pandemia Objetivo. Determinar los principales Eventos Adversos (EA) relacionados a la vacunación contra SARS-CoV-2 en el departamento de Córdoba, Colombia, en los años 2021-2022. Metodología estudio observacional descriptivo con intención analítica de tipo retrospectivo, utilizando el paquete estadístico Statistical Package for the Social Sciences version 27 (SPSS) y la prueba Kolmogórov-Smirnov Resultados que los EA se presentaron en estratos socioeconómicos más vulnerables y en mujeres. Los EA graves correspondieron a un promedio de edad de 30,2 con rango de 5 a 38 años, con mayor tasa en las versiones de AstraZeneca (ChAdOx1-S), CoronaVac® y Pfizer-BioNTech (BNT162b2) demostradas en los tres picos presentados en la administración de las vacunas. Conclusiones, evidencia una baja tasa de EA graves que se presentan luego de la vacunación contra SARS-Cov-2. Se debe tener cuenta las variables y determinantes socioeconómicas que influyen en los contextos de las personas que presentaron EA a la vacunación.The safety of the SARS-CoV-2 vaccine has been one of the concerns arising from the global coronavirus pandemic due to multiple clinical reactions observed in patients who received this type of agents to mitigate the impact of the pandemic. Objective: To determine the main Adverse Events (AE) related to SARS-CoV-2 vaccination in the department of Córdoba, Colombia, in the years 2021-2022. Methodology: Descriptive observational study with an analytical retrospective approach, using the Statistical Package for the Social Sciences version 27 (SPSS) and the Kolmogorov-Smirnov test. Results: AEs occurred more frequently in socioeconomically vulnerable strata and in women. Severe AEs had an average age of 30.2 with a range of 5 to 38 years, with a higher rate in the versions of AstraZeneca (ChAdOx1-S), CoronaVac®, and Pfizer-BioNTech (BNT162b2) demonstrated in the three peaks observed during vaccine administration. Conclusions: The evidence shows a low rate of severe AEs following SARS-CoV-2 vaccination. Socioeconomic variables and determinants influencing the contexts of individuals experiencing AEs during vaccination should be taken into accountEVENTOS ADVERSOS RELACIONADOS A LA VACUNACIÓN CONTRA SARS-COV-2 EN CÓRDOBA, COLOMBIA 2021-2022 1RESUMEN 14INTRODUCCIÓN 161. OBJETIVOS 181.1. OBJETIVO GENERAL 181.2. OBJETIVOS ESPECÍFICOS 182. MARCO REFERENCIAL 192.1. MARCO HISTORICO 192.2. MARCO TEÓRICO 222.2.1. Teoría general del sistema (TGS) 222.2.2. Seguridad del paciente y evento adverso. 242.2.3. Teoría del riesgo 282.2.4. Plataformas vacunales 292.3. MARCO CONCEPTUAL 312.4. MARCO INVESTIGATIVO 342.5. MARCO LEGAL 383. METODOLOGÍA 393.1. TIPO DE ESTUDIO 393.2. UNIDAD DE ANALISIS 403.3. SUJETO DE ESTUDIO 403.5.1. Criterios de inclusión 403.5.2. Criterios de inclusión 403.6. DESCRIPCIÓN DE LAS VARIABLES 413.7. TÉCNICAS Y PROCEDIMIENTOS 413.8. ACTIVIDADES 413.9. ANÁLISIS DE DATOS 433.10. ASPECTOS ÉTICOS 433.11. ASPECTOS DE LA PROPIEDAD INTELECTUAL 444. RESULTADOS 454.1. CARACTERÍSTICAS SOCIODEMOGRÁFICAS Y CLÍNICAS DE LOS INDIVIDUOS QUE PRESENTARON EVENTOS ADVERSOS EN CÓRDOBA. 454.1.1. Distribuciones estadísticas de uso de las plataformas vacunales en Córdoba. 454.2. CARACTERÍSTICAS SOCIODEMOGRÁFICAS Y CLÍNICAS DE LOS INDIVIDUOS QUE PRESENTARON EVENTOS ADVERSOS EN CÓRDOBA. 461.1. EVENTOS ADVERSOS GRAVES QUE SE REGISTRARON EN POBLACIÓN VACUNADA. 484.3. TASA DE EA Y MANIFESTACIONES CLÍNICAS RELACIONADAS CON EL TIPO DE VACUNA UTILIZADA CONTRA SARS-COV-2 EN EL DEPARTAMENTO DE CÓRDOBA, COLOMBIA. 502. DISCUSIÓN 523. CONCLUSIONES 55LIMITACIONES 56RECOMENDACIONES 56REFERENCIAS 58ANEXOS 66MaestríaMagíster en Salud PúblicaTrabajos de Investigación y/o Extensió
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