1,721,014 research outputs found
Binding of inositol hexakisphosphate to the oxygenated derivative of dromedary (Camelus dromedarius) and human hemoglobin: 31P-NMR study
FUNCTIONALIZATION OF POLYOLEFINS - DETERMINATION OF THE STRUCTURE OF FUNCTIONAL-GROUPS ATTACHED TO POLYETHYLENE BY FREE-RADICAL REACTIONS
FUNCTIONALIZATION OF POLYOLEFINS - STRUCTURE OF FUNCTIONAL-GROUPS IN POLYETHYLENE REACTED WITH ETHYL DIAZOACETATE
Carta d'Àngel Guiu, de la Fàbrica d'aserrar fusta d'Artesa de Segre al Sr.Àngel Boixareu de Pobla de Segur, 1923.
Carta d'Àngel Guiu, de la Fàbrica d'aserrar fusta d'Artesa de Segre al Sr.Àngel Boixareu de Pobla de Segur, 1923
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Unique structure of glycopeptide from alpha-fetoprotein produced in human hepatoma cell line, as determined by 1H-nuclear magnetic resonance spectroscopy.
Determination of alpha-fetoprotein is used in diagnosis of tumors and neural tube defects. A good reliable source of alpha-fetoprotein would be an obvious advantage to the preparation of diagnostic reagents and their standardization. We have recently developed a method for the production of alpha-fetoprotein from a human hepatoma cell line. This method, which is suitable for scaling up, allowed us to produce 40 g of alpha-fetoprotein from culture supernatant liquid through a simple purification procedure. We have previously shown this protein to be identical to alpha-fetoprotein produced from other sources. However, because the presence of different glycoforms has been reported in alpha-fetoprotein preparations, both from human sources and from other species, it was important to establish the type and extent of glycosylation of alpha-fetoprotein prepared by our method. By using 1H-NMR spectroscopy we were able to establish that our product contains a single N-linked biantennary, fully sialylated complex-type oligosaccharide, typical of human hepatomas
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