119,702 research outputs found
Montesia bosqi Seabra 1961
No full text793. Montesia bosqi Seabra, 1961: 264, fig. 2 Holotype male: Peru, Junin: Satipo.Published as part of Monné, Miguel A. & Monné, Marcela L., 2016, Checklist of Cerambycidae (Coleoptera) primary types of the Museu Nacional, Rio de Janeiro, Brazil, with a brief history of the collection, pp. 1-90 in Zootaxa 4110 (1) on page 59, DOI: 10.11646/zootaxa.4110.1.1, http://zenodo.org/record/25531
Meroscelisus thoracicus Seabra 1942
No full text1042. Meroscelisus thoracicus Seabra, 1942: 417, 2 figs Holotype male: Brazil, Espírito Santo: Matilde, X. 1939, A. Maller.Published as part of Monné, Miguel A. & Monné, Marcela L., 2016, Checklist of Cerambycidae (Coleoptera) primary types of the Museu Nacional, Rio de Janeiro, Brazil, with a brief history of the collection, pp. 1-90 in Zootaxa 4110 (1) on page 76, DOI: 10.11646/zootaxa.4110.1.1, http://zenodo.org/record/25531
Melzerella costalimai Seabra 1961
No full text<p> <b>791.</b> <i>Melzerella costalimai</i> Seabra, 1961: 263, 1 fig</p> <p>Holotype male: Venezuela, Eninbobo.</p>Published as part of <i>Monné, Miguel A. & Monné, Marcela L., 2016, Checklist of Cerambycidae (Coleoptera) primary types of the Museu Nacional, Rio de Janeiro, Brazil, with a brief history of the collection, pp. 1-90 in Zootaxa 4110 (1)</i> on page 58, DOI: 10.11646/zootaxa.4110.1.1, <a href="http://zenodo.org/record/255316">http://zenodo.org/record/255316</a>
Uma avaliação estratégica do sistema portuário catarinense
No full textTCC (Graduação) - Universidade Federal de Santa Catarina. Centro Socioeconômico. Curso de Graduação em Ciências Econômicas.O presente trabalho tem como finalidade a realização da avaliação técnica dos principais portos operantes do Estado de Santa Catarina, através da avaliação das operações de comércio exterior do Estado e seu desempenho. Trata ainda da relação com os demais modais de transporte e diagnostica os principais entraves e potencialidades que influenciam o sistema portuário catarinense, revelando o panorama atual do setor por meio da análise SWOT. Conclui-se que é priorizado melhorias ao modal rodoviário em detrimento do ferroviário e aquaviário. Obras de acesso ao porto, dragagem e melhoria na acostagem são alguns dos exemplos para todos os portos estudados, visando sempre interligar os modais promovendo a multimodalidade
Selective anticancer activity of a hexapeptide with sequence homology to a non-kinase domain of Cyclin Dependent Kinase 4
No full textBackground: cyclin-dependent kinases 2, 4 and 6 (Cdk2, Cdk4, Cdk6) are closely structurally homologous proteins which are classically understood to control the transition from the G1 to the S-phases of the cell cycle by combining with their appropriate cyclin D or cyclin E partners to form kinase-active holoenzymes. Deregulation of Cdk4 is widespread in human cancer, CDK4 gene knockout is highly protective against chemical and oncogene-mediated epithelial carcinogenesis, despite the continued presence of CDK2 and CDK6; and overexpresssion of Cdk4 promotes skin carcinogenesis. Surprisingly, however, Cdk4 kinase inhibitors have not yet fulfilled their expectation as 'blockbuster' anticancer agents. Resistance to inhibition of Cdk4 kinase in some cases could potentially be due to a non-kinase activity, as recently reported with epidermal growth factor receptor. Results: a search for a potential functional site of non-kinase activity present in Cdk4 but not Cdk2 or Cdk6 revealed a previously-unidentified loop on the outside of the C'-terminal non-kinase domain of Cdk4, containing a central amino-acid sequence, Pro-Arg-Gly-Pro-Arg-Pro (PRGPRP). An isolated hexapeptide with this sequence and its cyclic amphiphilic congeners are selectively lethal at high doses to a wide range of human cancer cell lines whilst sparing normal diploid keratinocytes and fibroblasts. Treated cancer cells do not exhibit the wide variability of dose response typically seen with other anticancer agents. Cancer cell killing by PRGPRP, in a cyclic amphiphilic cassette, requires cells to be in cycle but does not perturb cell cycle distribution and is accompanied by altered relative Cdk4/Cdk1 expression and selective decrease in ATP levels. Morphological features of apoptosis are absent and cancer cell death does not appear to involve autophagy. Conclusion: these findings suggest a potential new paradigm for the development of broad-spectrum cancer specific therapeutics with a companion diagnostic biomarker and a putative functional site for kinase-unrelated activities of Cdk4
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Capital humano, difusão tecnologica e convergência de rendas per capita :: uma análise de painel de dados para os estados brasileiros de 1985 a 1995 /
No full textDissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro Sócio-Econômico
Análise do comportamento da demanda por exportações de soja e de minério de ferro no Brasil
No full textTCC (graduação) - Universidade Federal de Santa Catarina. Centro Sócio-Econômico. Economia.O objetivo principal desse trabalho é uma análise da demanda por exportações de dois produtos, soja e minério de ferro, utilizando um modelo de equações simultâneas, entre as funções de oferta e demanda e estimação das elasticidades utilizando os métodos OLS Pooled, LSDV com efeitos fixos, GLS com efeitos aleatórios e GMM. Deste modo, procurou-se verificar as relações entre preço relativo, renda estrangeira, renda nacional e quantidade exportada adotando o modelo de dois países competitivos. Os resultados para as equações de oferta e demanda de exportações de soja indicaram que o preço relativo e a renda tem um alto poder explanatório na dinâmica desse comércio, verificando que a hipótese de que a curva de demanda apresenta uma elasticidade-preço finita não é adequada. Em relação ao minério de ferro, as variáveis preço relativo e renda apresentaram baixo poder explanatório, devido ao alto grau de concentração que se encontra esse mercado. Ainda em relação ao método de estimação, os resultados evidenciaram que a utilização de outros métodos que não o método dos momentos generalizados (GMM), resulta em inconsistência dos parâmetros, dado o efeito da inércia e suas implicações. De modo geral, a contribuição do presente trabalho foi uma tentativa de analisar o comportamento e os principais determinantes da demanda por exportações brasileiras de duas commodities: soja e minério de ferro. Além disso, do ponto de vista metodológico, buscou-se enfatizar, através da comparação entre os métodos econométricos utilizados, a importância de considerar aspectos de endogeinidade simultaneidade para a estimação de elasticidades robustas e consistente
Square Dancing with the Stars to Enhance Dynamic Hirschman Linkages?
No full textIn this Presidential Address, the author takes the reader on a reconnaissance of his life and time as a regional scientist. He points out scenery he found scintillating along the way, hoping that some may pick up the banner and chew on a few of the ideas for a while. He suggests a revisit to Albert O. Hirschman’s notion of key sectors and more empirical analysis related to Marcus Berliant’s and Masahisa Fujita’s notion of knowledge creation and transfer.Presidential Address, San Antonio, Texas, March 29, 2014 (53rd Meetings of the Southern Regional Science Association
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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