172,665 research outputs found

    This is the Date of Receipt Provided by Wagenmaker Schaaf for a Large Order of Supplies by Rev. Albertus C. Van Raalte

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    This is the date of receipt provided by Wagenmaker Schaaf for a large order of supplies by Rev. Albertus C. Van Raalte. There are thirteen items that are listed on the receipt. The order seems to be supplies for Van Raalte\u27s horses.https://digitalcommons.hope.edu/vrp_1860s/1560/thumbnail.jp

    SUTTONIIDAE Schaaf, 1976

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    Family SUTTONIIDAE Schaaf, 1976 sensu Dumitrica (2019) Suttonidae [sic] Schaaf, 1976: 790 (= Suttoniidae) [in Nassellaria]. — Dumitrica 1983b: 41 (sensu emend.) [in Spumellaria]. Suttoniidae – De Wever et al. 2001: 125-126 [in Spumellaria]. — Afanasieva et al. 2005: S284 [in Order Lobatiradiata]. — Afanasieva & Amon 2006: 126. — Dumitrica 2019: 40-41 (sensu emend.) TYPE GENUS. — Suttonium Schaaf, 1976: 790 [type species by monotypy: Suttonium praedicator Schaaf, 1976: 790]. INCLUDED GENERA (Cenozoic only). — Homunculodiscus Dumitrica, 2019: 41. — Parasuttonium Dumitrica, 2019: 47. — Suttonium Schaaf, 1976: 790. DIAGNOSIS. — Bilaterally symmetrical spumellarians with initial skeleton consisting of an eccentric microsphere with or without primary rays and a crescent shaped deuteroconcha. Skeleton thin made usually of two parallel lattice plates interconnected by short bars. Rays, when present, surrounded by a cortical shell forming three arms in the most evolved members (Dumitrica 2019: 40). STRATIGRAPHIC OCCURRENCE. — Early Paleocene-Holocene. REMARKS The internal skeletal structure of Homunculodiscus was already documented (Dumitrica 2019: figs 1.a-1.g, 2.a-2.h, 3a.-3.d, 4.a-4.d), Parasuttonium (Dumitrica 2019: figs 6.a, 6.b) and Suttonium (Dumitrica 2019: figs 6.c, 6.d). The taxonomic position of the Suttoniidae has been changed among Nassellaria, Spumellaria and Lobatiradiata. The history and the definition of the current taxonomic position was documented in Dumitrica (2019).Published as part of Suzuki, Noritoshi, Caulet, Jean-Pierre & Dumitrica, Paulian, 2021, A new integrated morpho- and molecular systematic classification of Cenozoic radiolarians (Class Polycystinea) - suprageneric taxonomy and logical nomenclatorial acts, pp. 405-573 in Geodiversitas 43 (15) on page 456, DOI: 10.5252/geodiversitas2021v43a15, http://zenodo.org/record/510175

    Identification of Sensitive Outcome Measures of Participation for Children With Autism

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    Abstract Date Presented 4/1/2017 Mixed methods were used to identify valid, reliable, performance-based outcome measures for daily living skills and socialization for children ages 6–9 with ASD. We chose the best measures. Feasibility and validity testing for use in a future comparative study is under way. Primary Author and Speaker: Roseann C. Schaaf Additional Authors and Speakers: Amy Carroll, Elizabeth M. Ridgway</jats:p

    Laser nitriding of metals

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    Laser nitriding can be described as the irradiation of metal surfaces by short laser pulses in nitrogen containing atmospheres. This may lead to a strong take-up of nitrogen into the metal and nitride formation which can improve the metal's surface properties, e.g. the hardness or the corrosion and wear resistance. Here, the laser nitriding of iron, carbon steel, stainless steel, and aluminum was investigated employing a combination of complementary methods. [on beam analysis (Rutherford Backscattering Spectroscopy and Resonant Nuclear Reaction Analysis) was employed for element and isotope profiling. Mossbauer spectroscopy and X-ray diffraction were used for phase analysis. Surface profilometry, optical and electron microscopy revealed the surface topography and morphology obtained after laser nitriding. Microhardness measurements by the nanoindentation technique characterized the mechanical surface properties obtained by the treatment. By this combination of methods it became possible to resolve the influence of the treatment parameters (laser fluence, number of pulses, spot size, spatial intensity distribution, and gas pressure) in different materials treated (iron, carbon steels and stainless steel). It is shown that laser nitriding is a complex process, composed of several superimposed effects. Laser heating, melting and evaporation in combination with plasma formation and the generation of laser-supported absorption waves are the essentials of the process. Pressure- and plasma-enhanced dissolution and diffusion of nitrogen in combination with macroscopic material transport (piston effect, convection, fall-out) are further important effects determining the results. Additional marker experiments and laser treatments in isotopically enriched nitrogen atmospheres allowed to analyze these effects and to develop scenarios for the nitriding process and the material transport mechanisms. A simulation of the nitrogen depth profiles for the single spot irradiations was derived, whose results are in good agreement with the experimentally observed profiles. (C) 2002 Elsevier Science Ltd. All rights reserved

    Voluntary reporting and systematic analysis of incidents in neonatal intensive care: the NEOSAFE study

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    Fetter, W.P.F. [Promotor]Schaaf, T.W. van der [Promotor]Molendijk, A. [Copromotor]Lingen, R.A. [Copromotor

    The phenotypic spectrum of Schaaf-Yang syndrome: 18 new affected individuals from 14 families

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    Purpose: Truncating mutations in the maternally imprinted, paternally expressed gene MAGEL2, which is located in the Prader-Willi critical region 15q11-13, have recently been reported to cause Schaaf -Yang syndrome, a Prader-Willi-like disease that manifests as developmental delay/intellectual disability, hypotonia, feeding difficulties, and autism spectrum disorder. The causality of the reported variants in the context of the patients' phenotypes was questioned, as MAGEL2 whole -gene deletions seem to cause little or no clinical phenotype. Methods: Here we report a total of 18 newly identified individuals with Schaaf-Yang syndrome from 14 families, including 1 family with 3 individuals found to be affected with a truncating variant of MAGEL2, 11 individuals who are clinically affected but were not tested molecularly, and a presymptomatic fetal sibling carrying the pathogenic MAGEL2 variant. Results: All cases harbor truncating mutations of MAGEL2, and nucleotides c.1990-1996 arise as a mutational hotspot, with 10 individuals and 1 fetus harboring a c.1996dupC (p.Q666fs) mutation and 2 fetuses harboring a c.1996deIC (p.Q666fs) mutation. The phenotypic spectrum of Schaaf-Yang syndrome ranges from fetal akinesia to neurobehavioral disease and contractures of the small finger joints. Conclusion: This study provides strong evidence for the pathogenicity of truncating mutations of the paternal allele of MAGEL2, refines the associated clinical phenotypes, and highlights implications for genetic counseling for affected families

    Neurophysiological Correlates of Sensory-Based Subtypes in Autism

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    Abstract Date Presented 3/30/2017 Substantial heterogeneity within the population of children with autism suggests possible sensory subtypes that may help to explain behavioral differences. This study considers objective neurophysiological measurements in response to sensory exposure as a means to better characterize such subtypes. Primary Author and Speaker: Kelle DeBoth Contributing Authors: Stacey Reynolds, Shelly J. Lane, Henry Carretta, Alison E. Lane, Roseann C. Schaaf</jats:p

    Elastic turbulence in two-dimensional Taylor-Couette flows

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    We report the onset of elastic turbulence in a two-dimensional Taylor-Couette geometry using numerical solutions of the Oldroyd-B model generated with the program OpenFOAM®. Beyond a critical Weissenberg number, an elastic instability causes a supercritical transition from the laminar Taylor-Couette flow to a turbulent flow. The order parameter, the time average of secondary-flow strength, follows the scaling law Φ(WiWic)γ\Phi \propto (\mathrm{Wi} -\mathrm{Wi}_c)^{\gamma} with Wic=10\mathrm{Wi}_c=10 and γ=0.45\gamma = 0.45 . Additionally, the flow resistance increases beyond Wic. The temporal power spectra of the velocity fluctuations show a power-law decay with a characteristic exponent in the range 232 3 , associated with elastic turbulence, for all Wi>Wic\mathrm{Wi} > \mathrm{Wi}_c

    FIGURE 4 in Cephaloscyllium ventriosum (Garman 1880) (Chondrichthyes: Carcharhiniformes: Scyliorhinidae), with comments on the status of C. uter (Jordan & Gilbert 1896)

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    FIGURE 4. – Pectoral fins of Cephaloscyllium ventriosum (MCZ 877) (left), and C. ventriosum (MCZ 1230) (right), both collected from Santa Barbara, California. Photo by J.A. S.-Da Silva.Published as part of Schaaf-Da, Jayna A. & Ebert, David A., 2008, Cephaloscyllium ventriosum (Garman 1880) (Chondrichthyes: Carcharhiniformes: Scyliorhinidae), with comments on the status of C. uter (Jordan & Gilbert 1896), pp. 59-68 in Zootaxa 1872 on page 65, DOI: 10.5281/zenodo.18402

    Phenotypic characterization of seven individuals with Marbach-Schaaf neurodevelopmental syndrome

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    International audienceWe present the phenotypes of seven previously unreported patients with Marbach-Schaaf neurodevelopmental syndrome, all carrying the same recurrent heterozygous missense variant c.1003C>T (p.Arg335Trp) in PRKAR1B. Clinical features of this cohort include global developmental delay and reduced sensitivity to pain, as well as behavioral anomalies. Only one of the seven patients reported here was formally diagnosed with autism spectrum disorder (ASD), while ASD-like features were described in others, overall indicating a lower prevalence of ASD in Marbach-Schaaf neurodevelopmental syndrome than previously assumed. The clinical spectrum of the current cohort is similar to that reported in the initial publication, delineating a complex developmental disorder with behavioral and neurologic features. PRKAR1B encodes the regulatory subunit R1beta of the protein kinase A complex (PKA), and is expressed in the adult and embryonal central nervous system in humans. PKA is crucial to a plethora of cellular signaling pathways, and its composition of different regulatory and catalytic subunits is cell-type specific. We discuss potential molecular disease mechanisms underlying the patients' phenotypes with respect to the different known functions of PKA in neurons, and the phenotypes of existing R1beta-deficient animal models
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