125,389 research outputs found
ERP Modulation during Observation of Abstract Paintings by Franz Kline
No full textThe aim of this study was to test the involvement of sensorimotor cortical circuits during the beholding of the static consequences of hand gestures devoid of any meaning.In order to verify this hypothesis we performed an EEG experiment presenting to participants images of abstract works of art with marked traces of brushstrokes. The EEG data were analyzed by using Event Related Potentials (ERPs). We aimed to demonstrate a direct involvement of sensorimotor cortical circuits during the beholding of these selected works of abstract art. The stimuli consisted of three different abstract black and white paintings by Franz Kline. Results verified our experimental hypothesis showing the activation of premotor and motor cortical areas during stimuli observation. In addition, abstract works of art observation elicited the activation of reward-related orbitofrontal areas, and cognitive categorization-related prefrontal areas. The cortical sensorimotor activation is a fundamental neurophysiological demonstration of the direct involvement of the cortical motor system in perception of static meaningless images belonging to abstract art. These results support the role of embodied simulation of artist's gestures in the perception of works of art. © 2013 Sbriscia-Fioretti et al
Emotional and Social Behaviors Elicited by Electrical Stimulation of the Insula in the Macaque Monkey.
No full text[Epub ahead of print
Motor Inhibition during Overt and Covert Actions: An Electrical Neuroimaging Study.
No full textGiven ample evidence for shared cortical structures involved in encoding actions, whether or not subsequently executed, a still unsolved problem is the identification of neural mechanisms of motor inhibition, preventing "covert actions" as motor imagery from being performed, in spite of the activation of the motor system. The principal aims of the present study were the evaluation of: 1) the presence in covert actions as motor imagery of putative motor inhibitory mechanisms; 2) their underlying cerebral sources; 3) their differences or similarities with respect to cerebral networks underpinning the inhibition of overt actions during a Go/NoGo task. For these purposes, we performed a high density EEG study evaluating the cerebral microstates and their related sources elicited during two types of Go/NoGo tasks, requiring the execution or withholding of an overt or a covert imagined action, respectively. Our results show for the first time the engagement during motor imagery of key nodes of a putative inhibitory network (including pre-supplementary motor area and right inferior frontal gyrus) partially overlapping with those activated for the inhibition of an overt action during the overt NoGo condition. At the same time, different patterns of temporal recruitment in these shared neural inhibitory substrates are shown, in accord with the intended overt or covert modality of action performance. The evidence that apparently divergent mechanisms such as controlled inhibition of overt actions and contingent automatic inhibition of covert actions do indeed share partially overlapping neural substrates, further challenges the rigid dichotomy between conscious, explicit, flexible and unconscious, implicit, inflexible forms of motor behavioral control
Proactive Control Strategies for Overt and Covert Go/NoGo Tasks: An Electrical Neuroimaging Study
No full textProactive and reactive inhibition are generally intended as mechanisms allowing the withholding or suppression of overt movements. Nonetheless, inhibition could also play a pivotal role during covert actions (i.e., potential motor acts not overtly performed, despite the activation of the motor system), such as Motor Imagery (MI). In a previous EEG study, we analyzed cerebral activities reactively triggered during two cued Go/NoGo tasks, requiring execution or withholding of overt or covert imagined actions, respectively. This study revealed activation of pre-supplementary motor area (pre-SMA) and right inferior frontal gyrus (rIFG), key nodes of the network underpinning reactive inhibition of overt responses in NoGo trials, also during MI enactment, enabling the covert nature of the imagined motor response. Taking into account possible proactive engagement of inhibitory mechanisms by cue signals, for an exhaustive interpretation of these previous findings in the present study we analyzed EEG activities elicited during the preparatory phase of our cued overt and covert Go/NoGo tasks. Our results demonstrate a substantial overlap of cerebral areas activated during proactive recruitment and subsequent reactive implementation of motor inhibition in both overt and covert actions; also, different involvement of pre-SMA and rIFG emerged, in accord with the intended type (covert or overt) of incoming motor responses. During preparation of the overt Go/NoGo task, the cue is encoded in a pragmatic mode, as it primes the possible overt motor response programs in motor and premotor cortex and, through preactivation of a pre-SMA-related decisional mechanism, it triggers a parallel preparation for successful response selection and/or inhibition during the response phase. Conversely, the preparatory strategy for the covert Go/NoGo task is centered on priming of an inhibitory mechanism in rIFG, tuned to the instructed covert modality of motor performance and instantiated during subsequent MI, which allows the imagined response to remain a potential motor act
Association between sleep disorders, hyperacusis and tinnitus: Evaluation with tinnitus questionnaires
No full textPatients with tinnitus are heterogeneous and several factors influence the impact of this symptom on the quality of life. The aim of the study is to evaluate the relationship between age, gender, sleep disorders, hyperacusis and tinnitus annoyance and to demonstrate the utility of tinnitus questionnaires as screening tools for sleep disorders and hyperacusis in patients with tinnitus. 37 consecutive patients (18 males and 19 females) with subjective tinnitus lasting over 3 months were evaluated with a complete interview, otological examination, pure tone audiometry, Italian version of tinnitus sample case history (TSCH) and tinnitus handicap inventory (THI). Statistical analysis was performed with the Wilcoxon′s rank sum test, the Spearman′s rho non-parametric correlation and the logistic regression analysis. THI grades were slight (16%), mild (32%), moderate (30%), severe (19%) and catastrophic (3%). Based on the answers to TSCH 20 patients reported sleep disorders (54%) and 20 patients reported hyperacusis (54%). 11 patients (30%) reported sleep disorders and hyperacusis. No significant correlation was found between the severity of tinnitus and patients′ age and gender. Significant correlation was found between sleep disorders (P = 0.0009) and tinnitus annoyance and between hyperacusis (P = 0.03) and tinnitus annoyance. TSCH and THI may be considered as screening tools in the clinical practice to evidence sleep disorders and hyperacusis in patients with tinnitus
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Multianalytical investigation of pigments in the Madonna della Croce wall painting (Triggiano, Italy)
No full textThe Madonna della Croce portrait is painted on a lunette, previously detached from a wall of unknown origin and now preserved on the right of the main altar in the Madonna della Croce church, in Triggiano (Bari, Italy). The wall painting, which depicts the Virgin and Child with St. Sebastiano and St. Rocco with their symbols of martyrium, was realised by a local artist who worked between 1550 and 1570 in the town.
The numerous legends about the wall painting, mixed with historical events, talk about miraculous healing stories which has strengthened the strong relationship of the Triggiano inhabitants with this religious symbol, such as they built a dedicated church and chose this Virgin as patron Saint of the town.
The presented research mainly focusses on the investigation of pictorial layers of this painting by a non-invasive multianalytical approach. Firstly, shape, size and optical features of pigments have been observed using a portable digital microscope equipped by a polarizing filter. By means of a portable spectrophotocolorimeter, colour of painting areas has been measured and expressed in the CIEL*a*b* system and for each of them reflectance spectra of visible light (400-700 nm) have been recorded. The identification of pigment composition has been carried out by FORS (fiber optic reflectance spectroscopy) and XRF (X-ray fluorescence spectroscopy). Produced spectra have been compared with databases available in literature.
Results have provided information about features and compositions of pigments, highlighting the use of red ochre, yellow ochre and carbon black for red and yellow paintings and for black profiles; in addition, mixing of red ochre and green earth and mixing of carbon black, lime and yellow ochre have been revealed respectively in correspondence to green background and blue Virgin mantle, as attested in other Apulian wall paintings (Fioretti et al. 2020; Fioretti et al. 2020)
Listeria monocytogenes meningitis in an immunocompromised patient
No full textThis report describes a case of meningitis caused by Listeria monocytogenes in a stem cell transplant recipient on immunosuppressive therapy for cutaneous chronic graft-versus host disease. A 59-year-old woman had undergone allogeneic stem cell transplantation (from a matched unrelated donor) 13 months previously for chronic lymphocytic leukemia. She was on regular hematologic follow-up. Though her previous malignancy has been in remission, she was immunosuppressed due to the pharmacological treatment. We describe a meningitis caused by a typical food-borne pathogen, dangerous in patients with impaired cell-mediated immunity. Moreover the bacterium had a multidrug resistance, a rare characteristic in clinical listeriosis. Rapid diagnosis and treatment are key factors in these cases. We chose ampicillin and rifampicin that allowed a complete resolution of the clinical manifestations
Individual Contacts, Collective Patterns. Prato 1975-97, a story of interactions.
No full textThis article presents an agent-based model (ABM) of an Italian textile district where thousands of small firms specialize in particular phases of fabrics production. It is an empirical model because it reconstructs the communications between firms when they arrange production chains. In their turn, production chains reflect into the pattern of road traffic in the geographical areas where the district extends. It is a methodological model because it aims to show that ABMs can be used to reconstruct a web of movements in geographical space. ABMs are proposed as a tool for Hägerstrand’s “time-geography”.Industrial districts, Industrial clusters, Agent-based models, Prato
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