150 research outputs found
La poesía de Vicente Cervera Salinas
No full textLa poesía de Vicente Cervera Salinas tiene como objeto de estudio la obra poética del ya citado poeta, con especial atención al poemario El alma oblicua. Se ha confeccionado la primera bio-bibliografía, en pro de dilucidar el capítulo de vivencias que motiva la gestación de los poemarios, mediante una serie de entrevistas al autor combinadas con la narración de los datos de manera externa. El criterio será el de agrupar estas vivencias por décadas, expuestas de manera diacrónica.
En el apartado de la contextualización, se abordan cómo los problemas aledaños a la teoría del canon han dictado que la poesía de Vicente Cervera Salinas no haya sido encumbrada con la celeridad que debiera. Se han rastreado las antologías más relevantes y las principales tendencias de la lírica española desde finales de los ochenta hasta el 2010.
Hemos incluido un análisis de los otros hábeas poéticos, donde se ha confeccionado una introducción general a los poemarios, un cuerpo analítico en el que aparece la delimitación de la macroestructura de la obra y un análisis de cada uno de los núcleos temáticos que lo integran, y finalmente, un capítulo de conclusiones. Los libros estudiados son De aurigas inmortales, La partitura y Escalada y otros poemas.
Sobre el arte poética de El alma oblicua, se ha practicado un estudio individualizado e inmanente para cada texto, aunque el análisis exegético-hermenéutico se ha vehiculado desde los parámetros esbozados en la introducción de cada uno de los decálogos, por ser éste el marbete que le otorga la cohesión a cada uno de los cuatro paradigmas del poemario. Cada uno de estos bloques contiene: una introducción que permite delinear el análisis, la praxis exegético-hermenéutica siguiendo el trenzado temático elegido en el punto anterior y un capítulo de conclusiones.
En el arte poética de “Oblicua”, la praxis se ha acometido estudiando el circunloquio y el ardid como huellas del ejercicio del pensamiento. El apartado consta de los siguientes epígrafes: descripción hermenéutica, análisis de los textos y conclusiones.
En el arte poética de “Gramática”, con análogas características a la metodología acuñada en el punto anterior, previa aproximación a un significado de ars recte dicendi, se estudió el modelo constructivo en el cual se fundamenta la creación de este conjunto de poemas: mediante los usos de la gramática en su relación con el demiurgo poético.
Con el arte poética de “Cautiva”, se estudió, previa aproximación a un significado de ‘Cautiva’, el modelo constructivo que estriba en la reinterpretación de la mística como elemento isotópico-conductor, dentro del plan metafísico-existencial que el demiurgo poético erige como actitud vital en su conquista hacia el camino de perfección.
Para el arte poético de “Panóptica”, el hilo interpretativo-vertebrador es el de la aceptación, por parte del yo poético, de la metamorfosis que implica la transformación de la vida en teatro, mediante su puesta en escena a través del artificio de la panóptica, y la conversión del poema en escenario.
En lo concerniente a la terminología, los estudios de referencia proceden de la Lingüística del Texto (J. Kristeva, el modelo de la TeSWeSt, T.A. Van Dijk …). La teoría de las tipologías textuales de Antonio García Berrio ha sido crucial en el estudio de El alma oblicua por decálogos (desde patrones semánticos que rigen su congruencia macroestructual). Por exigencia propias de la praxis hermenéutica y comparativa, se recoge también el concepto de microestructura y el de estructura como niveles graduales para llegar al reseñado. Finalmente, hemos acudido a las herramientas de la retórica en lo concerniente a operaciones creativas del discurso y los procedimientos estilísticos,The object of this study will focus on Cervera Salinas’ poetic work where special attention will be given to El alma oblicua (The Oblique Soul). The first bio-bibliography has been developed in order to shed light upon the personal experiences that were the cause of this set of poems, by means of a series of interviews with the author together with a compilation of information reported externally. We will resort to those experiences throughout the decades, exposed in a diachronic way.
In the contextualization section, we will deal with how the problems connected to the canon theory have dictated that Cervera Salinas’ poetic work has not been extolled in every literary circle for various reasons. To do this, we have been looking into the most outstanding anthologies and the main trends in Spanish poetry from the late 1980s to 2010.
A rough analysis of the other poetic books has been included, where we have drafted a general introduction to the set of poems, an analytic body, in which the work macrostructure limitation and an analysis of each thematic core is represented, and, finally, a chapter with the conclusions. The studied books are De aurigas inmortales, La partitura y Escalada y otros poemas.
As far as The Oblique Soul poetic art is concerned, a unique and immanent study of each poem has been provided, although the exegetic-hermeneutic approach has been carried out with the parameters outlined in the introduction of each Decalogue, as this is the label that gives cohesion to the four paradigms in the set of poems. Each block consists of an introduction that provides the analysis, the exegetic-hermeneutic praxis following the thematic pattern depicted in the former paragraph, and a chapter with the conclusions.
As for the “Oblicua” poetic art, the praxis has been carried out by means of a circumlocution and a ruse as traces left through the exercise of thought. This part consists of the following titles: a hermeneutic description, text analysis and conclusions.
In the “Gramatica” poetic art, with analogue methodological features coined in the former paragraph, prior approach to the meaning of ars recti dicendi, a constructive pattern based on the creation of this set of poems has been studied: through grammar usage linked to the poetic demiurge.
With “Cautiva” poetic art, we dealt with, after a semantic approach of “Cautiva, the constructive model that is based on the reinterpretation of the mysticism as an isotopic-leading element within a metaphysical-existential plan which the poetic demiurge stands as a vital attitude on his road to perfection.
As for the “Panóptica” poetic art, acceptance by the poetic-I is the interpretative-organizing thread of the metamorphosis that implies the transformation of life into drama, by means of his staging through the panoptic artifice, and the conversion of the poem into a stage.
Regarding the terminology, our references come from the world of Text Linguistics (J. Kristeva, Janos F. Petofi’s TeSWeSt model, T.A. Van Dijk...). Antonio García Berrio’s text typology theory has been crucial in developing The Oblique Soul in Decalogues (from semantic patterns that rule over their macrostructural coherence). Other important authors such as E. Bernárdez, Beaugrande and Dressler, J.M. Jiménez Cano, Vera Luján, T. Albadalejo Mayordomo and E. Ramón Trives will accompany us throughout the defence of this thesis.
Due to the peculiar requirements both the hermeneutic and comparative praxis entail, the concepts of microstructure and structure have also been included as graded levels to reach the reviewed one. Finally, rhetoric tools have been used to deal with discourse creative operations and stylistic procedures
CD44 modulates cell migration and invasion in Ewing sarcoma cells
No full textThe chimeric EWSR1::FLI1 transcription factor is the main oncogenic event in Ewing sarcoma. Recently, it has been proposed that EWSR1::FLI1 levels can fluctuate in Ewing sarcoma cells, giving rise to two cell populations. EWSR1::FLI1low cells present a migratory and invasive phenotype, while EWSR1::FLI1high cells are more proliferative. In this work, we described how the CD44 standard isoform (CD44s), a transmembrane protein involved in cell adhesion and migration, is overexpressed in the EWSR1::FLI1low phenotype. The functional characterization of CD44s (proliferation, clonogenicity, migration, and invasion ability) was performed in three doxycycline-inducible Ewing sarcoma cell models (A673, MHH-ES1, and CADO-ES1). As a result, CD44s expression reduced cell proliferation in all the cell lines tested without affecting clonogenicity. Additionally, CD44s increased cell migration in A673 and MHH-ES1, without effects in CADO-ES1. As hyaluronan is the main ligand of CD44s, its effect on migration ability was also assessed, showing that high molecular weight hyaluronic acid (HMW-HA) blocked cell migration while low molecular weight hyaluronic acid (LMW-HA) increased it. Invasion ability was correlated with CD44 expression in A673 and MHH-ES1 cell lines. CD44s, upregulated upon EWSR1::FLI1 knockdown, regulates cell migration and invasion in Ewing sarcoma cells.: This project was funded by Instituto de Salud Carlos III, grant numbers PI20CIII/00020,
DTS18CIII/00005, Asociación Pablo Ugarte, grant numbers TRPV205/18; Asociación Candela Riera,
Asociación Todos Somos Iván & Fundación Sonrisa de Alex, grant numbers TVP333-19, TVP-1324/15;
ASION, grant number TVP141/17. Enrique Fernández-Tabanera is supported by Asociación Candela
Riera, Asociación Todos Somos Iván & Fundación Sonrisa de Alex, Saint T. Cervera is supported by
Asociación Pablo Ugarte and Raquel M. Melero is supported by a CIBERER contract
CD44 Modulates Cell Migration and Invasion in Ewing Sarcoma Cells
No full textThe chimeric EWSR1::FLI1 transcription factor is the main oncogenic event in Ewing sarcoma. Recently, it has been proposed that EWSR1::FLI1 levels can fluctuate in Ewing sarcoma cells, giving rise to two cell populations. EWSR1::FLI1low cells present a migratory and invasive phenotype, while EWSR1::FLI1high cells are more proliferative. In this work, we described how the CD44 standard isoform (CD44s), a transmembrane protein involved in cell adhesion and migration, is overexpressed in the EWSR1::FLI1low phenotype. The functional characterization of CD44s (proliferation, clonogenicity, migration, and invasion ability) was performed in three doxycycline-inducible Ewing sarcoma cell models (A673, MHH-ES1, and CADO-ES1). As a result, CD44s expression reduced cell proliferation in all the cell lines tested without affecting clonogenicity. Additionally, CD44s increased cell migration in A673 and MHH-ES1, without effects in CADO-ES1. As hyaluronan is the main ligand of CD44s, its effect on migration ability was also assessed, showing that high molecular weight hyaluronic acid (HMW-HA) blocked cell migration while low molecular weight hyaluronic acid (LMW-HA) increased it. Invasion ability was correlated with CD44 expression in A673 and MHH-ES1 cell lines. CD44s, upregulated upon EWSR1::FLI1 knockdown, regulates cell migration and invasion in Ewing sarcoma cells.This project was funded by Instituto de Salud Carlos III, grant numbers PI20CIII/00020, DTS18CIII/00005, Asociación Pablo Ugarte, grant numbers TRPV205/18; Asociación Candela Riera, Asociación Todos Somos Iván & Fundación Sonrisa de Alex, grant numbers TVP333-19, TVP-1324/15; ASION, grant number TVP141/17. Enrique Fernández-Tabanera is supported by Asociación Candela Riera, Asociación Todos Somos Iván & Fundación Sonrisa de Alex, Saint T. Cervera is supported by Asociación Pablo Ugarte and Raquel M. Melero is supported by a CIBERER contract.S
IV Congreso ISUF-H “Forma urbis y territorios metropolitanos: Metrópolis en recomposición: Prospectivas proyectuales en el siglo XXI”
No full textUrban planning and urban design disciplines have been called to contribute for more sustainable communities. Approaching, describing, and measuring the urban metabolism calls therefore for the most appropriate tools to support the examination of the city from a sustainability point of view. Although prolific contributions have been advanced by the engineering disciplines, mainly in what regards the development of methods to quantify and measure the material flows that operate in the urban system, at the urban design sphere the study of the metabolism remains somehow obscure, delaying the necessary advances to guide the designing of the urban realm and of its necessary infrastructures to promote a sustainable city. This chapter summarises the research process promoted by the author of this manuscript, applied at Lisbon Metropolitan Areas, while promoting the study of the urban metabolism from a visualization perspective, for which the study of urban form proved to be fundamental. To do that, we examine the main contributions of the application of such visualization process, practiced in the past decade at Iscte - Lisbon University Institute, both in two specific financed research projects (MEMO and SPLACH) and at an academic domain, specifically at urban project studios of the Integrated Master of Architecture.info:eu-repo/semantics/acceptedVersio
IV Congreso ISUF-H “Forma urbis y territorios metropolitanos: Metrópolis en recomposición: Prospectivas proyectuales en el siglo XXI”
No full textUrban planning and urban design disciplines have been called to contribute for more sustainable communities. Approaching, describing, and measuring the urban metabolism calls therefore for the most appropriate tools to support the examination of the city from a sustainability point of view. Although prolific contributions have been advanced by the engineering disciplines, mainly in what regards the development of methods to quantify and measure the material flows that operate in the urban system, at the urban design sphere the study of the metabolism remains somehow obscure, delaying the necessary advances to guide the designing of the urban realm and of its necessary infrastructures to promote a sustainable city. This chapter summarises the research process promoted by the author of this manuscript, applied at Lisbon Metropolitan Areas, while promoting the study of the urban metabolism from a visualization perspective, for which the study of urban form proved to be fundamental. To do that, we examine the main contributions of the application of such visualization process, practiced in the past decade at Iscte - Lisbon University Institute, both in two specific financed research projects (MEMO and SPLACH) and at an academic domain, specifically at urban project studios of the Integrated Master of Architecture.info:eu-repo/semantics/acceptedVersio
Development of a telepresence robot for medical consultation
No full text© 2017 Author(s). There are numerous efforts to add value for telehealth applications in the country. In this study, the design of a telepresence doctor to facilitate remote medical consultations in the wards of Philippine General Hospital is proposed. This includes the design of a robot capable of performing a medical consultation with clear audio and video information for both ends. It also provides the operating doctor full control of the telepresence robot and gives a user-friendly interface for the controlling doctor. The results have shown that it provides a stable and reliable mobile medical service through the use of the telepresence robot
Urban form and urban metabolism. Recent research and academic trends conducted at the Lisbon Metropolitan Area
No full textUrban planning and urban design disciplines have been called to contribute for more sustainable communities. Approaching, describing, and measuring the urban metabolism calls therefore for the most appropriate tools to support the examination of the city from a sustainability point of view. Although prolific contributions have been advanced by the engineering disciplines, mainly in what regards the development of methods to quantify and measure the material flows that operate in the urban system, at the urban design sphere the study of the metabolism remains somehow obscure, delaying the necessary advances to guide the designing of the urban realm and of its necessary infrastructures to promote a sustainable city. This chapter summarises the research process promoted by the author of this manuscript, applied at Lisbon Metropolitan Areas, while promoting the study of the urban metabolism from a visualization perspective, for which the study of urban form proved to be fundamental. To do that, we examine the main contributions of the application of such visualization process, practiced in the past decade at Iscte - Lisbon University Institute, both in two specific financed research projects (MEMO and SPLACH) and at an academic domain, specifically at urban project studios of the Integrated Master of Architecture.info:eu-repo/semantics/publishedVersio
Urban form and urban metabolism. Recent research and academic trends conducted at the Lisbon Metropolitan Area
No full textUrban planning and urban design disciplines have been called to contribute for more sustainable communities. Approaching, describing, and measuring the urban metabolism calls therefore for the most appropriate tools to support the examination of the city from a sustainability point of view. Although prolific contributions have been advanced by the engineering disciplines, mainly in what regards the development of methods to quantify and measure the material flows that operate in the urban system, at the urban design sphere the study of the metabolism remains somehow obscure, delaying the necessary advances to guide the designing of the urban realm and of its necessary infrastructures to promote a sustainable city. This chapter summarises the research process promoted by the author of this manuscript, applied at Lisbon Metropolitan Areas, while promoting the study of the urban metabolism from a visualization perspective, for which the study of urban form proved to be fundamental. To do that, we examine the main contributions of the application of such visualization process, practiced in the past decade at Iscte - Lisbon University Institute, both in two specific financed research projects (MEMO and SPLACH) and at an academic domain, specifically at urban project studios of the Integrated Master of Architecture.info:eu-repo/semantics/publishedVersio
Non-coding RNA and transcriptional regulation in CD4 T cell lineages
No full textCD4 T cell lineage choice epitomises the ability of the immune system to become tailored to a specific threat and provides a framework for understanding the mechanisms behind cell specification. The differentiation of T effectors from naïve cells gives rise to pro-inflammatory lineages including T helper 1 (Th1) and Th2 and anti-inflammatory regulatory T cells (Treg). An additional lineage of Treg also exits the thymus in parallel to naïve T cells and together these Treg are required for prevention of autoimmunity. These T cell lineages are distinct in terms of their cytokine production and functional effects but also through their differences in gene expression and its regulation, which are orchestrated by the presence of lineage-specifying transcription factors specific for each lineage. In addition, post-translational modification of histones also provide insights into this transcriptional regulation and more recently the pervasive and tissue-specific transcription of multiple classes of RNA species without protein coding capacity, non-coding RNA (ncRNA), has been found to play a role in cell differentiation and function. In this thesis I identify several ncRNAs with differential expression different T cell lineages. This includes ncRNAs upregulated Treg compared to T responders. The characterisation of these, including their expression in the autoimmune context of systemic lupus erythematosus (SLE), is presented and their possible biological functions are examined. The relevance of histone modifications for influencing Treg identity in SLE is also investigated. An additional class of ncRNAs that originate from gene enhancer regions, eRNA, is also investigated in the context of Th1 versus Th2 lineage choice. This enhancer transcription is increased genome-wide in Th1 cells at enhancers with high density T-bet binding in, termed ‘super-enhancers’. The functional relevance of these eRNAs, including at the super-enhancer upstream of the Th1 signature cytokine gene, IFNG, is also investigated in knockdown experiments
Matrícula de tributos: un análisis. Antropología. Boletín Oficial del Instituto Nacional de Antropología e Historia. Num. 73 Nueva Época (2004) enero-marzo
No full textCervera, X., Adriana y María del Carmen López O.; “Identificación de materiales constitutivos y técnica de manufactura de los códices prehispánicos a través del análisis de las fuentes del siglo XVI”, México, ENCRyM, tesis para optar por el grado de licenciatura en Conservación y Restauración, 2000.Glass, John B.; Catálogo de la Colección de Códices, México, Museo Nacional de Antropología/INAH, 1964.González T., Carolusa; “El Tzautli: mucílago de orquídea. Obtención, usos y caracterización”, México, ENCRyM, tesis para optar por el grado de licenciatura en Conservación y Restauración, 1996.———; “Análisis de pigmentos en ocho códices mexicanos sobre piel”, Inglaterra, Montfort University, tesis para optar por el grado de maestría en Ciencias/Ciencias de la Conservación, 1998.Huerta C., Alejandro y Eugenia Berthier V.; “Códices, la ciencia al rescate”, en Antropología. Boletín Oficial del INAH, nueva época, núm. 59, julio-septiembre de 2000.Lenz, Hanz; El papel indígena mexicano, México, SEP (Sep-setentas, 65), 1973.Mohar Betancourt, Luz María; El tributo mexica en el siglo XVI: análisis de dos fuentes pictográficas, México, CIESAS (Cuadernos de la Casa Chata, 154), 1987.———; La escritura en el México antiguo, 2 vols., México, Plaza y Valdés, 1990.———; “La organización tributaria”, en Sonia Lombardo y Enrique Nalda (coords.), Temas Mesoamericanos, México, INAH, 1996.———; “De amate, colores y líneas en la Matrícula de Tributos”, en Códices y Documentos sobre México. Segundo Simposio, vol. II, México, INAH, 1997
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