2,784 research outputs found
Differential stability of 2'F-ANA*RNA and ANA*RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibility
No full text14 pags., 7 figs., 3 tabs.Hybrids of RNA with arabinonucleic acids 2′F-ANA and ANA have very similar structures but strikingly different thermal stabilities. We now present a thorough study combining NMR and other biophysical methods together with state-of-the-art theoretical calculations on a fully modified 10-mer hybrid duplex. Comparison between the solution structure of 2′F-ANA•RNA and ANA•RNA hybrids indicates that the increased binding affinity of 2′F-ANA is related to several subtle differences, most importantly a favorable pseudohydrogen bond (2′F-purine H8) which contrasts with unfavorable 2′-OH-nucleobase steric interactions in the case of ANA. While both 2′F-ANA and ANA strands maintained conformations in the southern/eastern sugar pucker range, the 2′F-ANA strand's structure was more compatible with the A-like structure of a hybrid duplex. No dramatic differences are found in terms of relative hydration for the two hybrids, but the ANA•RNA duplex showed lower uptake of counterions than its 2′F-ANA•RNA counterpart. Finally, while the two hybrid duplexes are of similar rigidities, 2′F-ANA single strands may be more suitably preorganized for duplex formation. Thus the dramatically increased stability of 2′F-ANA•RNA and ANA•RNA duplexes is caused by differencesin at least four areas, of which structure and pseudohydrogen bonding are the most important. © The Author(s) 2010. Published by Oxford University Press.Spanish Ministerio de Ciencia e Innovacion (grants
CTQ2007-68014-C02-02 to CG and BIO2009-10964 to
MO); Fundacion Marcelino Botin (grant to MO);
Canadian Institutes for Health Research (grant to
M.J.D.); Natural Sciences and Engineering Research
Council of Canada (postgraduate scholarship to
J.K.W.). Funding for open access charge: Canadian
Institutes for Health Research
Viajantes ex-cêntricas nas histórias de Ana Miranda
No full textTese (doutorado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-Graduação em Literatura.No conjunto das narrativas ficcionais da escritora brasileira Ana Miranda, a temática da viagem # considerada uma das mais férteis da literatura ocidental de todos os tempos # ocupa um espaço de centralidade, podendo até mesmo ser vista como o mais importante eixo de estruturação de suas obras. O estudo realizado pela presente tese tem por objetivo analisar o tratamento dado ao tema da viagem nos romances Desmundo, O retrato do rei, Dias & Dias e Amrik, evidenciando que por intermédio das narradora-viajantes # Oribela, Mariana, Feliciana e Amina # a autora promove um diálogo entre diferentes culturas, gêneros, etnias e gerações, ao mesmo tempo em que estabelece um profícuo diálogo com o passado em sua invariante problematização concernente aos limites e cruzamentos entre o discurso ficcional e os discursos narrativos extraliterários que o cercam, sobretudo o histórico e o biográfico. In the whole of Brazilian writer Ana Miranda#s fictional narrative, the travel thematic # considered one of the most fertile themes of the western literature of all times # occupies a central space, and can even been seen as the most important structuring axis of Miranda#s works. The aim of the present thesis is to analyze the treatment given to the travel subject in the novels Desmundo, O retrato do rei, Dias & Dias and Amrik, emphasizing that, through the traveling narrators, Oribela, Mariana, Feliciana and Amina, the author promotes a connection between different cultures, genders, ethnics and generations, at the same time that establishes a profitable dialogue with the past in her invariant problematization concerning the limits and crossings between the fictional and the extra-literary narrative discourses that surrounds it, mainly the historical and the biographic ones
El Tlacuache Núm. 400 (2010). 400 Año 10 (2010) enero. El Tlacuache
No full textLO QUE SUCEDÍA UN SIGLO ATRÁS Desgranando la memoria en Xochicalco por Elvira Pruneda. -Visitando al médico por Ana Cecilia Sánchez M
De la proposition, la phrase et l'énoncé dans la vision des linguistes M. Ioniţă et M. Potapova aux types de prédication et a l'ambiguïté dans la phrase simple tautologique et dans la phrase complexe comparative
No full textAbstract
In the article, the author undertakes a review of research by scientists M. Potapova and M. Ionita on sentence, phrase and utterance in order to submit further to analysis the types of predication in French and the ambiguity of a simple tautological phrase and a comparative compound one in this language.
Rezumat
În articol, autoarea îşi propune o retrospectivă a cercetărilor savanţilor M. Ioniţă şi M. Potapova asupra propoziţiei, frazei şi enunţului pentru a supune analizei, mai apoi, tipurile de predicaţie în franceză şi ambiguitatea frazei simple tautologice şi a celei compuse comparative în această limbă.Bondarenco, Ana. De la proposition, la phrase et l'énoncé dans la vision des linguistes M. Ioniţă et M. Potapova aux types de prédication et a l'ambiguïté dans la phrase simple tautologique et dans la phrase complexe comparative / A. Bondarenco // Limbaj şi context = Speech and Context : Rev. de lingvistică, semiotică şi şt. literară. – 2012. – Anul IV, nr. 1. - P. 23-44. – ISSN1857-4149
Stages for the More Sustainable Farm
No full textCurrently, agricultural farm units are faced with a double and most times contradictory challenge, in order to be successful: on the one hand the invested capital has to be profitable and the economic performance has to be maximised. On the other hand, given the socio-environmental situation, it is necessary to preserve and to protect the environment and natural resources. Given the potential conflict of the two aims, since the satisfaction of one implies the underperformance of the other (and vice versa), the question then is: which is the solution to choose? We intend, in this work, to formulate a farm plan with the purpose of reconciling the criteria of environmental sustainability with that of economic competitiveness. For this achievement we proceed to the comparative study of sustainability of different groups of farms identified in the study area (first evaluation cycle) through MESMIS (“Marco para la Evaluación de Sistemas de Manejo de Recursos Naturales Mediante Indicadores de Sustentabilidad” - Framework for Evaluation of Natural-Resource Systems Handling through Sustainability Indicators) methodology, that allowed to select the more sustainable group of farms. Based on the found potentialities and weakness on these production systems, we stepped to the planning of a production unit of bovine meat, which obeys simultaneously to economic and environmental objectives, using Multicriteria Decision. We finished the work with the sustainability evaluation between groups of farms identified previously and the planned farms (second evaluation cycle), based, again, in the MESMIS methodology, to confirm (or not) the greatest sustainability of the last ones. Analyses of the results allow us to confirm the greatest relative sustainability of the planned farm, for the diverse traced scenarios.Decision taking, planning, sustainability, Environmental Economics and Policy, Farm Management,
Cuestionando el estigma de la traición de los tlaxcaltecas. Una experiencia de reflexión ética en el museo. 32 Tercera época (2004) junio-septiembre. Gaceta de Museos. Cuestionando el estigma de la tradición de los tlaxcaltecas
No full textBEDOLLA, ANA G. Y MA. DE LOS ÁNGELES MORENO, Sin renunciar a la palabra. Pensar críticamente en los museos de historia, conferencia magistral, Congreso Internacional de Educación en Museos ICOM-CECA, Oaxaca, 2003.GARCÍA MORIYÓN, F., Investigación ética. Manual para acompañar a Lisa, De la Torre, Madrid, 1988.LIPMAN, M., Pensamiento complejo y educación, De la Torre, Madrid, 1998. SEP, Plan y programas de estudio. Educación básica. Secundaria, 1994
Efeito Ana C. : presença de Ana Cristina Cesar na poesia contemporânea brasileira
No full textOrientadora: Sandra M. StroparoDissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências Humanas, Programa de Pós-Graduação em Letras. Defesa : Curitiba, 31/05/2021Inclui referências: p. 141-151Área de concentração: Estudos LiteráriosResumo: A poeta carioca Ana Cristina Cesar é entendida como uma referência para diversos escritores contemporâneos em atuação. Sabendo disso, o presente trabalho procura investigar como o efeito da obra da poeta marginal opera na produção de seus herdeiros, partindo de três aspectos marcantes identificados na poética de Ana C.: linguagem, corpo e feminilidade. Para isso, foram analisadas as obras de dez escritores: Alice Sant'Anna, Ana Martins Marques, Angélica Freitas, Armando Freitas Filho, Ismar Tirelli Neto, Júlia de Carvalho Hansen, Laura Liuzzi, Marcos Siscar, Marília Garcia e Nina Rizzi. Escolheu-se, então, a metodologia de entrevistas, bem como a análise dos textos poéticos dos autores, de modo a compreender os dispositivos explorados pela poeta marginal na escrita contemporânea. Comparando os textos de Ana Cristina Cesar com a obra de seus herdeiros, é possível notar que essa presença produz uma forma de enunciação mais livre e permeada pela intimidade. Para a contextualização da obra da poeta, utiliza-se como base os trabalhos de Ítalo Moriconi (1996), Maria Lucia de Barros Camargo (2003) e Annita Costa Malufe (2010 e 2011). Como fundamentação teórica do efeito, recorreu-se a obra de Wolfgang Iser, em O ato da leitura (1996), que analisa a experiência da recepção do texto a partir dos efeitos de leitura que ele produz. Além disso, de modo a entender as relações que a poesia contemporânea estabelece com a tradição literária, recorreu-se às fundamentações de Marjorie Perloff, em O gênio não original: poesia por outros meios no novo século (2013). Identificando uma linhagem estética da poesia de Ana Cristina Cesar, é possível compreender os modos como sua escrita autorizou a experimentação de certas práticas poéticas, utilizando-se da escrita missiva, da intimidade e da alteridade.Abstract: Ana Cristina Cesar is understood as a reference for several contemporary writers. The present work seeks to investigate the effect of the poet's work in the works of her heirs, starting from three striking aspects identified in Ana C.'s poetry: language, body and femininity. With that in mind, we analyzed the works of ten poets: Alice Sant'Anna, Ana Martins Marques, Angélica Freitas, Armando Freitas Filho, Ismar Tirelli Neto, Júlia de Carvalho Hansen, Laura Liuzzi, Marcos Siscar, Marília Garcia and Nina Rizzi. We chose the methodology of interviews, as well as the analysis of the each author's poetry, in order to understand the devices explored by the marginal poet in contemporary writing. Comparing the texts of the marginal author with the work of her heirs, it is possible to notice that this presence produces a freer and more intimate form of enunciation. For the contextualization of her poetry, the works of Ítalo Moriconi (1996), Maria Lucia de Barros Camargo (2003) and Annita Costa Malufe (2010 and 2011) are used as a basis. As a theoretical basis for the effect, we used the work of Wolfgang Iser in The act of reading (1996), which analyzes the experience of reception from the reading effects the text produces. In order to understand the relationships that contemporary poetry establishes with literary tradition, we took Marjorie Perloff's foundations in Unoriginal genius: poetry by other means in the new century (2013). By identifying an aesthetic lineage of Ana Cristina Cesar's poetry, it is possible to understand the ways in which her writing authorized the experimentation of poetic practices, using missive writing, intimacy and otherness
Tagging of Biomedical Articles on CiteULike: A Comparison of User, Author and Professional Indexing
No full textThis paper examines the context of online indexing from the viewpoint of three different groups: users, authors, and professional indexers. User tags, author keywords and descriptors were collected from academic journal articles, which were both indexed in Pubmed and tagged on CiteULike, and analysed. Descriptive statistics, informetric measures, and thesaural term comparison shows that there are important differences in the use of keywords between the three groups in addition to similarities which can be used to enhance support for search and browse. While tags and author keywords were found that matched descriptors exactly, other terms which did not match but provided important expansion to the indexing lexicon were found. These additional terms could be used to enhance support for searching and browsing in article databases as well as to provide invaluable data for entry vocabulary and emergent terminology for regular updates to indexing systems. Additionally, the study suggests that tags support organisation by association to task, projects and subject while making important connections to traditional systems which classify into subject categories
Exposiciones con niños, una experiencia aleccionadora. 51 Tercera época (2011-2012) diciembre-marzo. Gaceta de Museos. Museos y Educación
No full textÁvila, Alejandro de (2000), “Tejidos que cuidan el alma”, en Textiles de Oaxaca, núm. 35, 2da. ed. México, Artes de México.Barabas, M. Alicia y M. Bartolomé Editores (1999), Configuraciones étnicas en Oaxaca. Perspercitvas Etnográficas para las Autonomías. México, INAH-INI.Barrera, Marco (2004), “Los niños de Santa Ana, portadores de cultura”, en Museos de México y del Mundo, núm. 2. México, CONACULTA/INAH/INBA.Bedolla G. Ana (1995), “Museso comunitarios: una experiencia social”, en México en el Tiempo, núm. 6. México, México Desconocido-INAH.(2005), “Hazme si puedes… relato sobre una exposición”, en
gaceta de museos 35. México, CONACULTA/INAH.(2010), “Expriencias institucionales de vinculación”, en gaceta de museos 47-48. México, CONANCULTA/INAH.Holidohler, C y E.O. Wilson (1996), Viaje a las hormigas. Barcelona, Grijalbo.Huxley, Julián (1971) Las hormigas. Buenos Aires, Centro Editor de América Latina.Lacouture, Felipe (1989), “La nueva museología: conceptos básicos y declaraciones”, en Artes Plásticas, vol. 2, núm. 3. México, UNAM.(1996) Conferencia dictada en el Museo Nacional de Culturas
Populares. Septiembre. México.Maeterlink, Maurice (1976), La vida de las hormigas. México, Populibros LaPrensa.Vázquez Olvera, Carlos (2005), Iker Larrauri Prado. Museógrafo mexicano. México, CONACULTA/INAH.Weitlaner J., Irngard. (2000), “Anatomía de una tradición textil”, en Textiles de Oaxaca. núm. 35, 2da. Ed. México, Artes de México
Determining the need for an expanded fitness component in the Fire Science Program at Milwaukee Area Technical College
No full textIncludes bibliographical references
- …
