1,721,853 research outputs found

    Dichtung und Wahrheit. Scarpa a Castelvecchio: l'invenzione della luce

    No full text
    Dichtung und Wahrheit. Scarpa a Castelvecchio: l'invenzione della luc

    Molecular approach in human tumor investigation: oncogenes, tumor suppressor genes and DNA tumor polyomaviruses.

    No full text
    Molecular analysis are useful for diagnosis, prognosis and follow-up of the patients, as well as for addressing therapeutic choices. Most of the molecular methods are based on the analysis of nucleic acids. The DNA and RNA methodologies of routine applicability include Southern and Northern hybridizations and polymerase chain reaction (PCR) techniques. Southern blot hybridization recognizes major DNA rearrangements, and detection of oncogenic viral sequences present in high copy number, whereas PCR-based methods allow the detection of gross chromosomal modifications, fine gene alterations and low amount of tumor virus footprints. PCR techniques also allow the analysis of the partially degraded nucleic acids from formalin-fixed paraffin-embedded tissues. We present an overview of the use of molecular techniques for the analysis, diagnosis, prognosis and follow-up of neoplastic diseases, using examples from our experience in both leukemias and solid tumors

    Sensori nano-gravimetrici: riduzione del fattore umidità mediante polimeri porosi superficiali

    Full text link
    One of the highest interfering for the determination of VOC's in the sensoristic' s field, is the humidity. in this thesis my aim is to develop a physic system able of to reduce the humidity factor. For this reason has been tested the influence of humidity against some nano-gravimetric sensors based on of quartz oscillating with fundamental frequency of 20 MHz, with surface modified with Me-porphyrines and Me-corroles with Langmuir-Schaefer technique (LS) before and after the deposition of six layers of Poly-methyl methacrylate porous (PMMA). The decrease of sensibility' s against the humidity in sensor modified in surface with PMMA porous, compared to the same unmodified, observed in the tests, carried out us to assert, that this method could be useful for the future development of sensors that isn' t influenced of humidity

    Going Beyond Counting First Authors in Author Co-citation Analysis

    Full text link
    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
    corecore