76,940 research outputs found

    Biography of Ceerno Ndiaye Ba

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    This manuscript is a biography of Ceerno Ndiaye Ba Bababe, in Mauritania. It is one of a series of biographies that the author has written about Islamic leaders in West Africa.Ce manuscrit est une biographie de Ceerno Ndiaye Ba Bababe, en Mauritanie. Elle fait partie d'une série de biographies que l'auteur a écrites sur les dirigeants islamiques en Afrique de l'Ouest

    Growth rate and superconducting properties of Gd-Ba-Cu-O bulk superconductors melt processed in air

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    A generic Mg-doped Nd-Ba-Cu-O seed crystal has been developed recently for the fabrication of any type of rare earth (RE) based (RE)-Ba-Cu-O single grain bulk superconductor in air. The new generic seed simplifies significantly the top seeded melt growth (TSMG) process for light rare earth based (Nd, Sm, Gd, or mixed rare earth elements) bulk superconductors, in particular. GdBCO single grains have been fabricated successfully in air using the new seed in a cold-seeding process. In this study, precursor powders were enriched with different amounts of BaO2 to investigate the extent of substitution of Gd for Ba in the Gd1+xBa2-xCu3O7-delta solid solution phase. The growth process of large single grains in air was investigated at various growth temperatures under isothermal processing conditions. Crystal growth rate as a function of under-cooling and BaO2 content has been determined from these experiments. The spatial variation of Tc and transition temperature width for applied field aligned along the a/b and c-axis of grains fabricated with different BaO2 content has also been investigated in order to understand the extent of the formation of Gd/Ba solid solution with varying growth temperature and precursor composition. These results have been used to establish the optimum conditions for fabricating solid solution-free, large single grains of GdBCO in air

    Poems of Sheikh Muhammad al-Ghaly Ba

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    This volume contains seven poems handwritten by Muhammad al-Ghāli Ba. According to the author's son, Mountaga Ba, the poems were probably composed in the mid-1970s a time when the author lived in Mauritania, while working at the country's national radio station and serving as a special counsel to then president Moktar Ould Daddah (1924–2003). The poems adress various issues. The first is a call to action addressed to the Mauritianian youth, urging them to join in the collective work for the development of the country. The second poem is a hagiography on Ceerno Ahmad Nene Ba of Kaedi (Mauritania). The poem eulogizes the virtues of the patron. The third describes the event of Sharif Muhammad al-Habib's visit to the region of Fuuta region (Senegal), namely the village of Pate Galo. The fourth poem contains greetings and expresions of love addressed to the author's friends in the town of Kaedi. The fifth poem is a remembrance about good times. The author reminisces and praises the qualities of a woman named Jaari.The sixth poem describes one afternoon journey of the author. The seventh poem is a mournful praisesong in which the author laments the loss of a cherished person.Ce volume contient sept poèmes manuscrits de Muhammad al-Ghāli Ba. Selon le fils de l'auteur, Mountaga Ba, les poèmes ont probablement été composés au milieu des années 1970, à une époque où l'auteur vivait en Mauritanie, alors qu'il travaillait à la radio nationale du pays et était conseiller spécial du président de l'époque, Moktar Ould Daddah (1924). –2003). Les poèmes abordent diverses questions. Le premier est un appel à l'action adressé aux jeunes mauriciens, les exhortant à s'associer au travail collectif pour le développement du pays. Le deuxième poème est une hagiographie sur Ceerno Ahmad Nene Ba de Kaedi (Mauritanie). Le poème fait l'éloge des vertus du mécène. Le troisième décrit l'événement de la visite de Sharif Muhammad al-Habib dans la région de la région de Fuuta (Sénégal), à savoir le village de Pate Galo. Le quatrième poème contient des salutations et des expressions d'amour adressées aux amis de l'auteur dans la ville de Kaedi. Le cinquième poème est un souvenir des bons moments. L'auteur rappelle et loue les qualités d'une femme nommée Jaari. Le sixième poème décrit un après-midi de voyage de l'auteur. Le septième poème est une louange mélancolique dans laquelle l'auteur déplore la perte d'une personne chérie

    Architect's drawing of BA Building, 1974

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    Architect's drawing of Business Arts Building (BA) (then Business and General Studies Building), with the Library on the right, 1974. Publicity photo for 1975 prospectus. Photo taken by S. Critchley

    Longitudinal analysis of serum neutralization of SARS-CoV-2 Omicron BA.2, BA.4, and BA.5 in patients receiving monoclonal antibodies

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    The emergence of Omicron sublineages impacts the therapeutic efficacy of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) monoclonal antibodies (mAbs). Here, we evaluate neutralization and antibody-dependent cellular cytotoxicity (ADCC) activities of 6 therapeutic mAbs against Delta, BA.2, BA.4, and BA.5. The Omicron subvariants escape most antibodies but remain sensitive to bebtelovimab and cilgavimab. Consistent with their shared spike sequence, BA.4 and BA.5 display identical neutralization profiles. Sotrovimab is the most efficient at eliciting ADCC. We also analyze 121 sera from 40 immunocompromised individuals up to 6 months after infusion of Ronapreve (imdevimab + casirivimab) or Evusheld (cilgavimab + tixagevimab). Sera from Ronapreve-treated individuals do not neutralize Omicron subvariants. Evusheld-treated individuals neutralize BA.2 and BA.5, but titers are reduced. A longitudinal evaluation of sera from Evusheld-treated patients reveals a slow decay of mAb levels and neutralization, which is faster against BA.5. Our data shed light on antiviral activities of therapeutic mAbs and the duration of effectiveness of Evusheld pre-exposure prophylaxis

    Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75

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    Recently emerged SARS-CoV-2 Omicron subvariant, BA.2.75, displayed a growth advantage over circulating BA.2.38, BA.2.76, and BA.5 in India. However, the underlying mechanisms for enhanced infectivity, especially compared with BA.5, remain unclear. Here, we show that BA.2.75 exhibits substantially higher affinity for host receptor angiotensin-converting enzyme 2 (ACE2) than BA.5 and other variants. Structural analyses of BA.2.75 spike shows its decreased thermostability and increased frequency of the receptor binding domain (RBD) in the “up” conformation under acidic conditions, suggesting enhanced low-pH-endosomal cell entry. Relative to BA.4/BA.5, BA.2.75 exhibits reduced evasion of humoral immunity from BA.1/BA.2 breakthrough-infection convalescent plasma but greater evasion of Delta breakthrough-infection convalescent plasma. BA.5 breakthrough-infection plasma also exhibits weaker neutralization against BA.2.75 than BA.5, mainly due to BA.2.75’s distinct neutralizing antibody (NAb) escape pattern. Antibody therapeutics Evusheld and Bebtelovimab remain effective against BA.2.75. These results suggest BA.2.75 may prevail after BA.4/BA.5, and its increased receptor-binding capability could support further immune-evasive mutations

    [[alternative]]A Pedagogical Grammar of the Chinese Disposal(Ba) Construction

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    [[abstract]]Current pedagogical grammar of the Chinese disposal construction (ba) is based on Shou-hsin Teng’s theoretical framework and methodology in his A Pedagogical Grammar of Chinese (2003), which draws on 7,710 examples from a corpus of authentic material and theoretical linguistics/grammar research, and emphasizes the learner as a crucial parameter, providing an exhaustive description of the Chinese disposal construction. In my thesis, I identify three semantic functions of the Chinese disposal construction based on Teng’s theoretical framework: disposal, accidental, and causative. (The disposal semantic function comprises 94.53% of the 7,288 examples in the Academia Sinica Corpus.) Additionally, I seek to establish seven basic sub-structures of the disposal construction: ba 1) S ba OV + aspect; ba 2) S ba OV + result; ba 3) S ba OV + goal; ba 4) S ba OV + direction; ba 5) S ba OV + extent; ba 6) S ba OV + range; ba 7) S ba OV + reduplication. Drawing on Teng’s principles regarding multiple sequences and the assessment of the difficulty grammar of points, I posit eight principles for assessing the difficulty of seven disposal construction sub-structures, and order such sub-structures according to their level of difficulty; in so doing, I assess the sequencing, pedagogical stages, and grading of the sub-structures, and create a model for disposal construction pedagogy which includes a series of computer-based, task-oriented scenarios. I believe my thesis can help bridge the gap between the fields of pedagogical grammar and pedagogy, and provide a discursive platform on which relevant issues can be further examined. Hopefully, my research and the potential discursive platform arising from it will lend themselves to discrediting the common belief that disposal construction pedagogy is best formulated according to an educator’s personal experiences. This thesis thereby situates the pedagogy of the disposal construction firmly in the realm of empirical science. Additionally, I seek to help educators to develop their pedagogical methodology according to my sequence of the disposal construction, and to systematically improve their teaching methods. In so doing, educators will enable second language learners not only to fully grasp the disposal construction and other related grammar points, but also to grasp the entirety of the Chinese grammar system. Thus they will ultimately allow learners to actively engage speakers of the target language in an appropriate, effective manner.

    Monitoring of the SARS-CoV-2 Omicron BA.1/BA.2 lineage transition in the Swedish population reveals increased viral RNA levels in BA.2 cases

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    BACKGROUND: Throughout the SARS-CoV-2 pandemic, multiple waves of variants of concern have swept across populations, leading to a chain of new and yet more contagious variants dominating COVID-19 cases. Here, we tracked the remarkably rapid shift from Omicron BA.1 to BA.2 sublineage dominance in the Swedish population in early 2022 at a day-by-day basis. METHODS: Using a custom SARS-CoV-2 Omicron BA.1 lineage-typing RT-PCR assay, we analyzed 174,933 clinical upper airway samples collected during January to March 2022. FINDINGS: Our study demonstrates the feasibility and reliability of parallel lineage assignment of select variants at population scale, tracking the dominant sublineage transition from BA.1 to BA.2 at day-to-day resolution and uncovering nearly 2-fold higher levels of viral RNA in cases infected with Omicron BA.2 relative to BA.1. CONCLUSIONS: Our data provide unique insights into the Omicron BA.1 to BA.2 transition that occurred in Sweden during early 2022, and later, across the world. This may help to understand the increased transmissibility of the BA.2 variant

    Végzős BA/BSc-s hallgatók munkaerőpiaci attitűdjei

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    Marton Melinda (2010): Végzős BA/BSc-s hallgatók munkaerőpiaci attitűdjei

    GAUGE-INVARIANT FORMULATION OF THE S, T, AND U PARAMETERS

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    It is shown that the bosonic contributions to the S, T, and U parameters, defined in terms of conventional self-energies, are gauge dependent in the standard model (SM). Moreover, T and U are divergent unless a constraint is imposed among the gauge parameters. Implications of this result for renormalization schemes of the SM are discussed. A gauge-invariant formulation of S, T, and U is proposed in the pinch-technique framework. The modified S, T, and U parameters provide a gauge-invariant parametrization of leading electroweak radiative corrections in the SM and some of its extensions
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