3,282 research outputs found
The effect of patients’ preference on outcome in the EVerT cryotherapy versus salicylic acid for the treatment of plantar warts (verruca) trial
Background
Randomised controlled trials are widely accepted as the gold standard method to evaluate medical interventions, but they are still open to bias. One such bias is the effect of patient’s preference on outcome measures. The aims of this study were to examine whether patients’ treatment preference affected clearance of plantar warts and explore whether there were any associations between patients’ treatment preference and baseline variables in the EverT trial.
Methods
Two hundred and forty patients were recruited from University podiatry schools, NHS podiatry clinics and primary care. Patients were aged 12 years and over and had at least one plantar wart which was suitable for treatment with salicylic acid and cryotherapy. Patients were asked their treatment preference prior to randomisation. The Kruskal-Wallis test was performed to test the association between preference group and continuous baseline variables. The Fisher’s exact test was performed to test the association between preference group and categorical baseline variables. A logistic regression analysis was undertaken with verruca clearance (yes or no) as the dependent variable and treatment, age, type of verruca, previous treatment, treatment preference as independent variables. Two analyses were undertaken, one using the health professional reported outcome and one using the patient’s self reported outcomes. Data on whether the patient found it necessary to stop the treatment to which they had been allocated and whether they started another treatment were summarised by treatment group.
Results
Pre-randomisation preferences were: 10% for salicylic acid; 42% for cryotherapy and 48% no treatment preference. There was no evidence of an association between treatment preference group and either patient (p=0.95) or healthcare professional (p=0.46) reported verruca clearance rates. There was no evidence of an association between preference group and any of the baseline variables except gender, with more females expressing a preference for salicylic acid (p=0.004). There was no evidence that the number of times salicylic acid was applied was different between the preference groups at one week (p=0.89) or at three weeks (p=0.24). Similarly, for the number of clinic visits for cryotherapy (p=0.71)
Conclusions
This secondary analysis showed no evidence to suggest that patients’ baseline preferences affected verruca clearance rates or adherence with the treatment
Statsvetenskap, särskilt bostadspolitik (Political science, especially housing policy)
Presentation of Evert Vedung´s research life</p
Interview Evert Nijland
Interview met sieraadontwerper Evert Nijland over het ontstaan van zijn werk van concept tot uitvoering, inclusief draagbaarheid en overerving. Het begint bij inspiratie en het ontwerpen, gevolgd door een onderzoeksfase en samenwerking, tot en met het technisch perfectioneren en het voltooien van de serie met het slotstuk. Daarna volgen verkopen (galerie Rob Koudijs; PAN), verzamelen (V&A; Rijksmuseum), dragen (particulieren), exposeren (CODA; USA) en restaureren. Een bijzonder verhaal over overerving is de levensgeschiedenis van een collier van wijlen Dorelies Kraakman. Materiaaltechnisch ligt de nadruk op glas veelal in combinatie met andere materialen, zoals zilver en flock. Hiervoor werkt Nijland samen met glasblazer Edwin Dieperink, zilvergieter Steffan van Slooten, 3D print ontwerper David van der Veldt en sieraadontwerper Merel Slootheer. Door het samenbrengen van tegenstellingen in zowel inhoud als vorm, gaat hij steeds nieuwe uitdagingen aan in het maakproces waardoor een aantal nieuwe technische mogelijkheden zijn ontwikkeld, zoals het verwerken van glas in zilver, en een gietmethode die tijdens dit interview plastic perdu wordt gedoopt
A WaCky introduction
In this article we discuss four different ways of using the Web as a corpus, focusing particularly on those taking the lion share of this volume of working papers: the Web as a “corpus shop”, and the “mega-corpus/mini-Web” as a new object. The latter in particular will be described in some detail, and special attention will be paid to the design of this resource and the challenges posed by its development
Evert Nijland over glas
Sieraadontwerper Evert Nijland vertelt over glas, zijn fascinatie voor het materiaal, de uitdaging om ermee te werken en de dualiteit die het in zich draagt. Zesentwintig keer valt het woord ‘spannend’ en dat is ook precies wat hij zoekt in zijn ontwerpen en materiaalcombinaties. Daar gaat een lang proces van ontwikkeling en trial en error aan vooraf in een intensieve samenwerking met verschillende vakspecialisten waardoor bijzondere nieuwe materiaaltoepassingen ontstaan
Evert Nijland on glass
Sieraadontwerper Evert Nijland vertelt over glas, zijn fascinatie voor het materiaal, de uitdaging om ermee te werken en de dualiteit die het in zich draagt. Zesentwintig keer valt het woord ‘spannend’ en dat is ook precies wat hij zoekt in zijn ontwerpen en materiaalcombinaties. Daar gaat een lang proces van ontwikkeling en trial en error aan vooraf in een intensieve samenwerking met verschillende vakspecialisten waardoor bijzondere nieuwe materiaaltoepassingen ontstaan
Testing the extrapolation quality of word frequency models
In this paper, we present a thorough testing of various LNRE (Large Number or Rare Events) models for the prediction of vocabulary size and other quantities at sizes larger than the sample size. The main conclusion is that none of the models appears to be empirically adequate. Preliminary evidence suggests that this might be due to non-randomness effects
Politisk idéanalys och den danska debatten om demokratins kris (Analysis of political ideas and the Danish debate on democracy´s crisis)
Evert Vedungs opposition vid Palle Svenssons disputation vid Aarhus universitet.</p
"""America's sweetheart,"" Chris Evert: Celebrity femininity and tennis in postmodern America"
"Chris Evert is one of the most significant cultural figures to emerge in late twentieth century America. Her storied career has produced a ubiquitous image that remains highly visible within culture. As an ""American sweetheart,"" Evert draws her meaning as a sign for national/gendered identity largely from the differences embodied in her well-chronicled rivalry with Martina Navratilova. Although Martina eclipsed her career record in tournament wins and earnings, ""Chrissie"" remains one of the predominant female sports icons of the postmodern era. Evidence of a profuse literature detailing her career, image and effects within culture stands in sharp contrast to the dearth of scholarly literature which probes meanings of countless narratives about Evert's career. This dissertation opens a space for the theoretical consideration of salient features and meanings produced in the dispersion of Evert's image. The underlying theoretical strategies provided by conjunctural analysis are informed by feminist cultural studies, poststructuralism, performative theory and postmodernism. The strategies employed do not seek to uncover truths so much as to examine the means by which power and truths are produced within culture."Made available in DSpace on 2011-05-07T12:40:32Z (GMT). No. of bitstreams: 2
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