4,113 research outputs found
Fertility Preservation in Gynecological Cancer: Current Management and Novel Insights
No full textGynecological cancers are usually diagnosed in women after menopause, particularly in western countries. However, a non-negligible proportion of cases are diagnosed in younger women in the reproductive age. In these patients, appropriate counseling, including discussing the long-term consequences of the different treatment options on fertility and the possibility of fertility preservation, is mandatory as in any cancer diagnosis. However, women affected by gynecological cancer require considering that the treatment options include hysterectomy and bilateral oophorectomy in most cases. Therefore, in gynecological cancer, often, the standard treatment consists of an inevitable loss of fertility. The direct consequence is that fertility preservation management does not usually include the optimal treatment of the disease, with the risk of worsening oncologic outcomes. Particularly for endometrial cancer and ovarian cancer, the diagnosis in reproductive age additionally carries the risk of hereditary cancer. Therefore, the counseling needs to include discussing a genetic assessment of cancer risk to identify an inherited predisposition. This factor is even more paramount when a fertility-sparing approach to achieve a subsequent pregnancy is considered. Regardless of these general principles, gynecological cancers are heterogeneous, and fertility-sparing management needs to be personalized, with different options for each type of cancer. These options include both fertility preservation treatments already used in other cancers, such as oocyte cryopreservation, and specific therapeutic options unique for each diagnosis. Moreover, given the reproductive organs are involved by the disease, the adoption of the traditional fertility preservation treatments is not always feasible and require specific considerations. This book was thought and written for this complex scenario to provide a complete and detailed overview of the fertility preservation management options in young women affected by gynecological cancers. This book discusses of all the elements involved in the management of these patients: the role of genetic assessment and counseling, the effect of anticancer treatments for gynecological cancer on fertility, the classic fertility preservation techniques adapted to gynecological cancer, the detailed and specific fertility preservation management for cervical, ovarian, and endometrial cancer, and finally the role of a multidisciplinary approach in these patients. This book will provide a starting point to approach the management of highly delicate patients in his total
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No full textData of the project described in the Proposal attached on this website.
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For the use of this data and/or theoretical model written consent from Magdalena Garzon Fonseca is required. The appropriate contribution of this author should be stated in any publication resulting from this data and/or theoretical mode
Mapping the Horizon of Transformative Peace
No full textThis article explores what it means for peace to be transformative and discusses what it takes for a peace project and its institutions to enable transformative peace. To address these questions the article offers a theoretical and conceptual approach and draws on< some examples from case studies, especially Colombia. The article deals with the resistance that transformative projects might face from the victims they are meant to benefit. It promotes an understanding of conflict and resistance as essential dimensions to bring about positive transformations in violent contexts. In so doing, the author shows that the possibilities offered by normative-based frameworks to build transformative peace are curtailed by principles such as neutrality and impartiality of international law. These principles have resulted in institutional gender and race blindness that precludes the possibilities of a peace project being transformative.Thus, she offers a debate on two aspects that might condition or enable transformative forms of peace: the temporalities of peacebuilding and the inclusion of dissensus. Building on this the author proposes an understanding of transformative peace as an orientation that has on its horizon people’s emancipation from structural oppressions. This understanding will allow peace institutions more realistic time-space scales and the opportunity to benefit from the difference and dissensus that the practice of peacemaking might have left aside.Sonia Garzon Ramirez holds a PhD in Comparative Gender Studies from the Central European University, Budapest (Hungary). From 2020 to 2022, Sonia was a Marie Skłodowska-Curie postdoctoral fellow at the Department of International Politics, Aberystwyth University (UK). In 2021, she was a visiting researcher at swisspeace with the Dealing with the Past (DwP) team. Her current research examines nonviolent resistance and contestation to peacebuilding. Sonia combines feminist theory, intersectionality and agonistic theory to investigate how dissensus participates in shaping peacebuilding and bringing about transformative peace
Some disagreements with Ernesto Garzon on Human Rights
No full textEl texto recoge la respuesta del autor del libro citado a las tres observaciones que Ernesto Garzón realizó en el prólogo del mismo. Las discrepancias giran en torno a la historicidad de las concepciones de los derechos humanos defendida por el autor y cuestionada por el prologuista; al modelo de organización internacional exigido por las teorías de los derechos humanos: una asociación de Estados democráticos o una institución internacional democrática e «intervencionista» en materia de derechos humanos; y a la relevancia moral del principio de dignidad humana que el autor circunscribe a fundamentar los derechos de la personalidad y de seguridad, mientras Garzón lo amplia a fundamentar una regulación jurídica moralmente aceptable.This text constitutes the answer of the author of the above quoted book to three comments about it formulated by Ernesto Garzón in its prologue. These comments referred to disagreements about the historicity of the human rights theories proposed by the author and criticised by Garzon; the pattern of international organization required by these human rights theories: an association of democratic States versus a democratic international institution which is «interventionist» in the field of human rights; and the moral relevance of the principle of human dignity which the author bases on identity and «rule of law» rights, while Garzon considers it to be more generally the basement of a morally acceptable legal order
Ruolo della terapia ormonale prima della miomectomia isteriscopica
No full textLa chirurgia isteroscopica rappresenta il gold standard di riferimento per il trattamento minin- vasivo di diverse patologie intrauterine, tra le quali i polipi, le malformazioni congenite tra cui il setto uterino o la cavità uterina a T, le sinechie endometriali, l’iperplasia endometriale resistente a trattamento medico, e i miomi uterini (1–3). Nello specifico, la miomectomia isteroscopica rap- presenta il trattamento standard dei miomi uterini sottomucosi (4–7)
Algunas discrepancias con Ernesto Garzón en materia de derechos humanos
No full textThis text constitutes the answer of the author of the above quoted book to three comments about it formulated by Ernesto Garzón in its prologue. These comments referred to disagreements about the historicity of the human rights theories proposed by the author and criticised by Garzon; the pattern of international organization required by these human rights theories: an association of democratic States versus a democratic international institution which is «interventionist» in the field of human rights; and the moral relevance of the principle of human dignity which the author bases on identity and «rule of law» rights, while Garzon considers it to be more generally the basement of a morally acceptable legal order.El texto recoge la respuesta del autor del libro citado a las tres observaciones que Ernesto Garzón realizó en el prólogo del mismo. Las discrepancias giran en torno a la historicidad de las concepciones de los derechos humanos defendida por el autor y cuestionada por el prologuista; al modelo de organización internacional exigido por las teorías de los derechos humanos: una asociación de Estados democráticos o una institución internacional democrática e «intervencionista» en materia de derechos humanos; y a la relevancia moral del principio de dignidad humana que el autor circunscribe a fundamentar los derechos de la personalidad y de seguridad, mientras Garzón lo amplia a fundamentar una regulación jurídica moralmente aceptable
The use of satellite data to calibrate a hydrodynamic model of the Venice Lagoon
No full textThe use of satellite data to calibrate a hydrodynamic model of the Venice Lagoon was discussed. Three couples of Landsat data was processed to retrieve the surface water temperature of the lagoon. A two-dimensional (2D) finite elements hydrodynamic model was developed to stimulate the tidal level within the lagoon considering all the variables related to morphological and astronomical factors
Paul Chambdal, Savoir, Devoir, Pouvoir la Science moderne et les fondements de l'éthique. J. L. Peset, S. Garma, J. S. Pérez Garzon, Ciencias y ensenanza en la revolution burguesa
No full textPaul Chambdal, Savoir, Devoir, Pouvoir la Science moderne et les fondements de l'éthique. J. L. Peset, S. Garma, J. S. Pérez Garzon, Ciencias y ensenanza en la revolution burguesa. In: Revue d'histoire des sciences, tome 35, n°1, 1982. pp. 76-78
Paul Chambdal, Savoir, Devoir, Pouvoir la Science moderne et les fondements de l'éthique. J. L. Peset, S. Garma, J. S. Pérez Garzon, Ciencias y ensenanza en la revolution burguesa
No full textPaul Chambdal, Savoir, Devoir, Pouvoir la Science moderne et les fondements de l'éthique. J. L. Peset, S. Garma, J. S. Pérez Garzon, Ciencias y ensenanza en la revolution burguesa. In: Revue d'histoire des sciences, tome 35, n°1, 1982. pp. 76-78
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