1,437 research outputs found
Congestión venosa en paciente con d-TGA tras Mustard
No full textF.J. Ruperti-Repilado está financiado por la subvención Nº 214198 de la Swiss National Science Foundation.Peer reviewe
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Roughness Induced Boundary Layer Transition in Incompressible Flow
No full textThe fluid dynamics process leading to laminar-turbulent transition behind an isolated roughness element is investigated in the incompressible regime using particle image velocimetry. The study covers the effect of roughness size and geometry on the promotion of transition. The measurement domain covers a large streamwise range from the near wake to the onset of the turbulent regime. Planar PIV measurements reveal the basic flow pattern and the turbulent structure of the flow characterizing by the velocity fluctuation statistics (RMS of the streamwise and wall-normal velocity component and Reynolds shear stress). The high Reynolds shear stress level reaching the region near the wall in the downstream area indicates the onset of turbulent boundary layer
Young adults after arterial switch operation for transposition of the great arteries in Switzerland: a growing population.
No full textBACKGROUND
Adults with transposition of the great arteries (d-TGA) after the arterial switch operation (ASO) are an evolving cohort in adult cardiology. We aimed to analyze cardiac function and cardiac events after transition to the adult clinic in Switzerland.
MATERIALS AND METHODS
Adults with prior ASO enrolled in the Swiss Adult Congenital HEart disease Registry (SACHER) were included. We analyzed initial cardiac anatomy, surgical history, residual lesions and cardiac function at the time of inclusion, as well as cardiac events during follow-up. Patients were classified as complex (with ventricular septal defect) or simple (with intact interventricular septum) d-TGA.
RESULTS
The cohort included 149 patients (99 simple d-TGA, 50 complex d-TGA; age 21±3 years; 71% male, follow-up 27 [15-46] months). Prior to inclusion, patients with complex d-TGA had undergone more interventions related to the left ventricular outflow tract (16% vs. 3%, p = 0.01). Functional and cardiovascular status were similar between the groups. Eleven patients (7%) had a total of 19 cardiac events (5 complications and 14 re-interventions) during follow-up. Patients with complex d-TGA had more cardiac-related complications compared to those with simple d-TGA (8% vs. 1%, p = 0.03). The frequency of re-interventions was not statistically different between the two groups (12% vs. 4%, p = 0.07). During follow-up, an increase in QRS duration was observed. Other parameters of cardiac function remained unchanged.
CONCLUSION
The majority of adult ASO patients have normal functional class and cardiac function. Complex anatomy and residual lesions play a key role when regarding the occurrence of cardiac-related complications during follow-up. The role of QRS prolongation over time needs to be investigated further
Keterampilan Hukum, Panduan untuk Mahasiswa, Akademisi dan Praktisi
No full textSkills book for Indonesian students and lawyers in Indonesian, based on the skills method of the Faculty of Law of Maastricht University. Each chapter has been written by a different author, but the overall structure is based on the structure of Vaardigheden voor juristen
Heart Failure and Patient-Reported Outcomes in Adults With Congenital Heart Disease from 15 Countries.
No full textBackground Heart failure (HF) is the leading cause of mortality and associated with significant morbidity in adults with congenital heart disease. We sought to assess the association between HF and patient-report outcomes in adults with congenital heart disease. Methods and Results As part of the APPROACH-IS (Assessment of Patterns of Patient-Reported Outcomes in Adults with Congenital Heart disease-International Study), we collected data on HF status and patient-reported outcomes in 3959 patients from 15 countries across 5 continents. Patient-report outcomes were: perceived health status (12-item Short Form Health Survey), quality of life (Linear Analogue Scale and Satisfaction with Life Scale), sense of coherence-13, psychological distress (Hospital Anxiety and Depression Scale), and illness perception (Brief Illness Perception Questionnaire). In this sample, 137 (3.5%) had HF at the time of investigation, 298 (7.5%) had a history of HF, and 3524 (89.0%) had no current or past episode of HF. Patients with current or past HF were older and had a higher prevalence of complex congenital heart disease, arrhythmias, implantable cardioverter-defibrillators, other clinical comorbidities, and mood disorders than those who never had HF. Patients with HF had worse physical functioning, mental functioning, quality of life, satisfaction with life, sense of coherence, depressive symptoms, and illness perception scores. Magnitudes of differences were large for physical functioning and illness perception and moderate for mental functioning, quality of life, and depressive symptoms. Conclusions HF in adults with congenital heart disease is associated with poorer patient-reported outcomes, with large effect sizes for physical functioning and illness perception. Registration URL: https://clinicaltrials.gov; Unique identifier: NCT02150603
Goda Karte
No full textStamoed certificate which reads; Edmonton Latvian Society Imanta. F.J. Baker1.0 Imanta, 1.1.1 Historyof Imanta in Albert
Agglomeration in suspension: A study of mechanisms and kinetics
No full textMechanical, Maritime and Materials Engineerin
High-resolution EM-CCD scintillation gamma cameras
No full textThe development of medical imaging techniques has dramatically changed clinical practice and biomedical science in the 20th century. Nuclear Medicine imaging techniques reveal the function of organs and tissues in vivo with the aid of radioactively labeled tracer molecules. These techniques, such as Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET), are clinically applied in the fields of neurology, oncology, cardiology, skeletal and thyroid imaging. Applied to small animals, these techniques are important tools in development of better diagnostics and new drugs and fundamental biological research. For small animal SPECT systems, pinhole magnification enables image resolutions below 0.3 mm using conventional Anger cameras with an intrinsic spatial resolution of only 3 to 4 mm. There is a large desire to improve the spatial resolution of the gamma detectors to further improve the preclinical and clinical SPECT performance as well as to make systems more compact. This thesis focuses on EM-CCD based scintillation gamma cameras with a very high spatial resolution, more than 10 times better than conventional Anger cameras. Therefore these EM-CCD gamma cameras are a candidate for the next generation of pre-clinical-SPECT scanners. In pinhole SPECT cameras the spatial resolution is severely degraded for gamma photons incident at an angle, called the depth-of-interaction effect. We showed that this effect can be overcome using a novel curved scintillator geometry which results in a scintillation light centroid independent of the depth-of-interaction. Alternatively we strongly reduced the depth-of-interaction effect by using a multi scale algorithm that detects the scintillation depth. This depth is determined by modelling the variation of the scintillation light spread with depth. If we also take the statistics of the detector into account using a Maximum Likelihood scintillation detection algorithm the energy resolution of the detector improves significantly. Furthermore, using the Cramer Rao lower bound we showed that the EM-CCD based gamma camera performance is very sensitive to the scintillator light yield and the Clock Induced Charge (CIC) and dark current noise. A feasible reduction of these noise sources would improve the gamma camera performance significantly.RRRApplied Science
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