7,852 research outputs found
Supplementary materials for "Sexually dimorphic regulation of gonadotrope cell hyperplasia in medaka pituitary via mitosis and transdifferentiation"
This file is a supplementary figures for the manuscript "Sexually dimorphic regulation of gonadotrope cell hyperplasia in medaka pituitary via mitosis and transdifferentiation"The two pituitary gonadotropins, Fsh and Lh, regulate the reproductive function in vertebrates. While many studies have investigated the regulation of gonadotropin production and release by the sex steroid feedback, its role on the regulation of gonadotrope cell number remains unclear. Using medaka as a model and an optimized protocol to restore physiological sex steroids levels following gonadectomy, we show that gonadal sex steroids not only decrease fshb transcript levels, but also Fsh cell number in both sexes. We then investigated the origin of the Fsh cell hyperplasia induced by gonadectomy. In both sexes, BrdU incubation shows that this is achieved via Fsh cell mitosis. In situ hybridization reveals that new Fsh cells also originate from transdifferentiating Tsh cells in females, but not in males. Both phenomena are inhibited by sex steroid supplementation via feeding. In males (but not females), gonadectomy (without recovery with sex steroid supplementation) also reduces sox2 transcript levels and Sox2-immunopositive population volume, suggesting that sox2-progenitors may be recruited to produce new Fsh cells. Opposite to Fsh cells, gonadectomy decreases lhb levels in both sexes, and levels are not restored by sex steroid supplementation. In addition, the regulation of Lh cell number also seems to be sex dependent. Removal of gonadal sex steroids stimulates Lh cell mitosis in male (like Fsh cells), but not in females. To conclude, our study provides the first evidence on sexually dimorphic mechanisms used in the fish pituitary to remodel gonadotrope populations in response to sex steroids
Pioneers of Library Movement in Pakistan
The paper aims to describe in brief the contribution of seven leaders of Pakistan librarianship, viz. K.B. Khalifa M. Asadullah, Prof. Dr. Abdul Moid, Dr. Abdus Subuh Qasimi, Muhammad Shafi, Fazal Elahi, Khawaja Nur Elahi and S. V. Hussain. The early library developments are given for better understanding of the role of these leaders
The Complete Muhammad Ali
Including material and photographs not included in most of the 100 other books about the champion, Ishmael Reed's The Complete Muhammad Ali is more than just a biography-it is a fascinating portrait of the 20th century and the beginning of the 21st. An honest, balanced portrayal of Ali, the book includes voices that have been omitted from other books. It charts Ali's evolution from Black Nationalism to a universalism, but does not discount the Nation of Islam and Black Nationalism's important influence on his intellectual development. Filipino American author Emil Guillermo speaks about how "The Thrilla' In Manila" brought the Philippines into the 20th century. Fans of Muhammad Ali, boxing fans, and those interested in modern African American history and the Nation of Islam will be fascinated by this biography by an accomplished American author.Intro -- DEDICATION -- INTRODUCTION -- The Curious History of an Icon -- CHAPTER 1 -- CHAPTER 2 -- CHAPTER 3 -- CHAPTER 4 -- CHAPTER 5 -- CHAPTER 6 -- CHAPTER 7 -- Did the Secret Government Fear a U.S. Muslim/Overseas Muslim Alliance? -- CHAPTER 8 -- CHAPTER 9 -- The Break Between the Prophet and his Disciple -- CHAPTER 10 -- CHAPTER 11 -- CHAPTER 12 -- The GOAT (Greatest Of All Time): Ali or Louis? -- CHAPTER 13 -- The Nation of Islam, the Mob, Showdowns in Canada and Sonny Liston -- CHAPTER 14 -- CHAPTER 15 -- The Taunts: Marketing or Racism? -- CHAPTER 16 -- CHAPTER 17 -- CHAPTER 18 -- CHAPTER 19 -- Boxing and the Brain -- CHAPTER 20 -- Ali's Feet -- CHAPTER 21 -- Mr. Dick -- CHAPTER 22 -- CHAPTER 23 -- The Opening Ceremonies, November 2005 -- CHAPTER 24 -- December 2005, Las Vegas -- CHAPTER 25 -- CHAPTER 26 -- June 16, 2004 -- CHAPTER 27 -- CHAPTER 28 -- CHAPTER 29 -- Aix-en-Provence -- CHAPTER 30 -- Ali as a Black Nationalist -- San Francisco, January 2004 Black Liberation Book Fair -- CHAPTER 31 -- January 31, 2004 -- CHAPTER 32 -- October 2005, Chicago -- CHAPTER 33 -- Why Ali remained with Elijah instead of following Malcolm -- CHAPTER 34 -- CHAPTER 35 -- February 4, 2006, Oakland, California -- CHAPTER 36 -- Like Zeus Descending from Mount Olympus -- CHAPTER 37 -- CHAPTER 38 -- Tuesday, February 28, 2006, New York -- CHAPTER 39 -- Bigger Than Boxing -- CHAPTER 40 -- Tribes Gallery, New York, April 2006 -- CHAPTER 41 -- June 2006, Louisville, Kentucky -- CHAPTER 42 -- CHAPTER 43 -- CHAPTER 45 -- Bad Company -- CHAPTER 46 -- Coxson, A Very Charming Rogue -- CHAPTER 47 -- Ali and the largest embezzlement scheme in Wells Fargo history -- CHAPTER 48 -- CHAPTER 49 -- "Lonnie is a stabilizing force."-Harry Belafonte -- October 29, 2006 -- CHAPTER 50 -- Abdul Rahman -- CHAPTER 51 -- CHAPTER 52 -- CHAPTER 53How Will Ali Be Remembered? New York, January 8, 2005 -- CHAPTER 54 -- CONCLUSION -- AFTERWORD -- Boxers' Rights? -- BIBLIOGRAPHY -- MUHAMMAD ALI -- ISLAM AND NATION OF ISLAM -- BOXING -- RELATED SUBJECTS -- ALSO AVAILABLE FROM BARAKA BOOKSIncluding material and photographs not included in most of the 100 other books about the champion, Ishmael Reed's The Complete Muhammad Ali is more than just a biography-it is a fascinating portrait of the 20th century and the beginning of the 21st. An honest, balanced portrayal of Ali, the book includes voices that have been omitted from other books. It charts Ali's evolution from Black Nationalism to a universalism, but does not discount the Nation of Islam and Black Nationalism's important influence on his intellectual development. Filipino American author Emil Guillermo speaks about how "The Thrilla' In Manila" brought the Philippines into the 20th century. Fans of Muhammad Ali, boxing fans, and those interested in modern African American history and the Nation of Islam will be fascinated by this biography by an accomplished American author.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
Replication Data for: 3D atlas of the pituitary gland of the model fish medaka (Oryzias latipes)
The imaging files are the supplementary figures for paper entitled "3D atlas of the pituitary gland of the model fish medaka". The files are hyperstack TIFF files images showing channels corresponding to endocrine cell markers, including blood vessels, in the pituitary of juvenile and adult male and female medaka
PENGARUH KUALITAS PRODUK, KUALITAS PELAYANAN, DAN HARGA TERHADAP PENDAPATAN KEDAI KOPI ABAH KOTA BLITAR
Skripsi dengan judul “Pengaruh Kualitas Produk, Kualitas Pelayanan, dan Harga terhadap Pendapatan Kedai Kopi Abah Kota Blitar” ini ditulis oleh Muhammad Nizar Royan, NIM 12405173090, pembimbing Dr. H. Ahmad Muhtadi Anshor, M.Ag.
Penelitian ini dilatar belakangi oleh kompetisi bisnis di dunia kopi di Blitar tampak semakin kompetitif. Persaingan kualitas produk, kualitas pelayanan dan harga begitu sengit, menuntut para pelaku bisnis kopi untuk dapat menyediakan produk-produk yang berkualitas dan harga yang terjangkau oleh konsumen. Pelaku bisnis juga diharapkan dapat mengembangkan suatu produk yang bermanfaat dan inovatif sesuai dengan harapan konsumen dan kebutuhan pasar, sehingga kepuasan konsumen dapat diperoleh dan akan membuat konsumen melakukan pembelian dimasa yang akan datang.
Penelitian ini berfokus pada 1. adakah pengaruh kualitas produk terhadap pendapatan Kedai Kopi Abah Kota Blitar?, 2. adakah pengaruh kualitas pelayanan terhadap pendapatan Kedai Kopi Abah Kota Blitar?, 3. adakah pengaruh harga terhadap pendapatan Kedai Kopi Abah Kota Blitar?, dan 4. adakah pengaruh kualitas produk, kualitas pelayanan, dan harga terhadap pendapatan Kedai Kopi Abah Kota Blitar?
Penelitian ini menggunakan pendekatan kuantitatif dan jenis penelitian asosiatif. Metode pengambilan sampel dalam penelitian ini adalah Clauser Random Sampling dengan sampel sebanyak 80 responden. Sumber data yang digunakan dalam penelitian ini data primer (kuesioner) dengan pengukuran menggunakan skala likert. Kemudian hasil kuesioner dianalisis menggunakan uji instrumen data yaitu uji validitas, uji reliabilitas, uji asumsi klasik, uji regresi linier berganda, uji hipotesis yaitu uji parsial, uji simultan, serta uji koefisien determinasi.
Hasil penelitian ini menunjukkan bahwa 1) terdapat pengaruh variabel kualitas produk terhadap pendapatan Kedai Kopi Abah Kota Blitar, 2) terdapat pengaruh variabel kualitas pelayanan terhadap pendapatan terhadap pendapatan Kedai Kopi Abah Kota Blitar, 3) terdapat pengaruh variabel harga terhadap pendapatan Kedai Kopi Abah Kota Blitar, dan 4) terdapat pengaruh variabel kualitas produk, kualitas pelayanan, dan harga secara bersama-sama terhadap pendapatan Kedai Kopi Abah Kota Blitar.
Kata kunci: Kualitas Produk, Kualitas Pelayanan, Harga dan Pendapata
Nilai Pendidikan Karakter Dalam Kitab Washaya Al-Aba’ Li Al-Abna Karya Muhammad Syakir Al-Iskandari
This research aims to identify the character education values contained in the book Washaya al-Aba' li al-Abna Muhammad Syakir and the role of his opinion on the richness of character education values. It is hoped that this research can be used as a source or reference in efforts to develop education and character as a whole, especially character education according to Islam. It can also be used as a reference to facilitate understanding of character education and as a reference for relevant research in the future. This research method is qualitative and uses a narrative biography method. By using a descriptive presentation approach, this autobiography of the character's thoughts combines the ideas of character education from his work. Library research, or library research, is a research method that involves books, articles, notes and electronic media. with primary sources from the book Washaya al Aba Li al-Abna and secondary sources from study books. In this research, data collection was carried out through the documentation method, which includes searching for data through variables such as notes, books, and articles, among others. The author used a content analysis study to analyze the data; they analyzed the data textually based on the contents of the book. The research results show that the book Washaya al Aba Li al-Abna contains 17 educational character values, divided into two categories: 10 character values fall into the moral category and 7 character values fall into the performance category. Faith and piety, love and obedience to the Messenger of Allah, respect for parents, respect for teachers, truth or honesty, nobility or self-respect, patience, sincerity and a simple life are moral characters. Performance characteristics also include trust, discipline, hard work, never giving up, love of the country, interest in reading or literacy knowledge, and concern for the environment
Modern Human Essence in the Quran: Comparative Views of Muhammad Iqbal and Plato
This study explores the essence and dimensions of modern humanity from the perspective of the Quran, focusing on the views of Muhammad Iqbal and Plato. In modern society, there is a prevailing notion that religion and science are irreconcilable entities, complicating the understanding of their relationship. This study aims to analyze the views of Iqbal and Plato on the essence and dimensions of modern humanity. The research method employed is a literature review, utilizing primary data from Iqbal's “The Reconstruction of Religious Thought in Islam” and Plato's “The Republic.” Secondary data include books, journals, essays, and other relevant sources. The findings indicate that Iqbal perceives the essence of humanity in its spiritual entity, complemented by intelligence, belief, and morality, while Plato identifies three essential elements of humanity: spirit, reason (intellect), and desire (appetite)
Biography of Muhammad Baba
Ce manuscrit est une biographie du savant islamique Muhammad Baba du village de Doumga, au Sénégal. Elle fait partie d'une série de biographies que l'auteur a écrites sur les dirigeants islamiques en Afrique de l'Ouest.This manuscript is a biography of Islamic scholarMuhammad Baba of the village of Doumga, in Senegal. It is one of a series of biographies that the author has written about Islamic leaders in West Africa
Some Letters by Muhammad al-Ghāli Ba
Ce manuscrit comprend des correspondances et un article. Les correspondances étaient destinées à plusieurs personnes. L'article a été réécrit lorsque l'auteur, Muhammad al-Ghali, travaillait à la radio nationale mauritanienne. L'article traite de la situation politique de la Mauritanie dans les années 80. Il discute des relations entre les partis politiques existants en Mauritanie.This manuscript includes correspondences and one article. The correspondences had been destined to several people. The article was written back when the author, Muhammad al-Ghali, was working at Mauritania' s National Radio. The article addresses the political situation of Mauritania in the 1980s. It discusses the relationship between the existing political parties in Mauritanian
Hydraulic simulations to evaluate and predict design and operation of the Chashma Right Bank Canal
Irrigation systems / Irrigation canals / Flow control / Velocity / Canal regulation techniques / Hydraulics / Simulation models / Design / Operations / Crop-based irrigation / Distributary canals / Water delivery / Policy / Protective irrigation / Water allocation / Water requirements / Sedimentation / Water distribution / Equity / Water conveyance / Pakistan / Chashma Right Bank Canal
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