1,720,960 research outputs found
Pengaruh Pemberian Formalin Peroral Terhadap Mukosa Lambung Tikus Putih Strain Wistar (Rattus Norvegicus Strain Wistar)
Full text linkThe Effect of Oral Formalin on Gastric Mucosa of Wistar Strain White Rats (Rattus Norvegicus Wistar Strain) Background: Gastritis represent one of more disease in clinic, on 2001 prevalention of cronic gastritis in Indonesia 4.3% of 100.000 population and caused additive like formaldehyde. Formaldehyde was misused especially in food industry, if consumed can cause organ’s disparity. Intention of this research is prove the Effect of Formaldehyde peroral subacute on the stomach mucosal of White Rat Strain Wistar (Rattus Norvegicus strain wistar)Method : The design of the study was pure experimental which usingThe Posttest Control Group Design. Sample were white mice which divided into 4 groups. Group I is as a control, without formaldehyde, and another groups were given with formaldehyde doses 20 ppm, 40 ppm, and 80 ppm. Result: The results should that formaldehyde can cause hyperplasia, hypertrophic, atopic, chafe (ANOVA p=0.000). The mechanism of action possibility as DNA cross-linked by protein than gene expression anormal. Conclusions: The study concluded that formaldehyde can cause hyperplasia, hypertrophic, atopic, and chafe on the mucosal stomach of white rat strain wistar and further study was needed to know minimum doses than can change of stomach mucosal and than mecahanism of action about them
Self-Management Education pada Pasien Diabetes Melitus
Full text linkDiabetes self-management education (DSME) integrates four aspects of diabetes management with an emphasis on behavioral interventions that assist individuals with diabetes in adopting lifestyle changes for their self-care from the desease. DSME encompasses diets, exercises, treatments, and exercise schedules for patients with diabetes, aiming to enhance patients\u27 ability to self-care. This study aimed to assess the effects of DSME on the self-care of patients with diabetes by using a booklet medium at Purwokerto Islamic Hospital. This quantitative research employed a quasi experimental design with a control group pre-post test design and gave a booklet media to the intervention group. This research involved 32 randomly selected respondents who were divided into control and intervention group. The statistical analysis used an independent t-test and showed a significant difference in the care of patients with diabetes (p=0.00<0.05) between the two groups. Following DSME intervention, 75% respondents in the intervention group exhibited a good self-care behavior; meanwhile, the control group was just 56%. The statistical analysis showed a difference in the self-care mean of the intervention group, which improved meaningfully (p-value 0.01); however, the control group was unmeaningful (p-value 0.06). This research showed DSME is able to improve the self-care of patients with diabetes mellitus.Diabetes self-management education (DSME) memadukan empat aspek manajemen diabetes dengan penekanan pada intervensi perilaku yang membantu individu dengan diabetes dalam mengadopsi perubahan gaya hidup untuk merawat diri mereka dari penyakit ini. DSME meliputi diet, olahraga, perawatan, dan jadwal olahraga bagi penderita diabetes, bertujuan untuk meningkatkan kemampuan pasien dalam merawat diri yang dikenal sebagai self-care. Penelitian ini bertujuan untuk menilai pengaruh DSME terhadap perawatan diri pasien diabetes menggunakan media booklet di Rumah Sakit Islam (RSI) Purwokerto. Penelitian kuantitatif ini menggunakan desain kuasi eksperimen dengan desain control group pre–posttest dan membagi media booklet kepada kelompok intervensi. Penelitian ini melibatkan 32 responden yang dipilih secara acak dan dibagi menjadi kelompok kontrol dan kelompok intervensi. Analisis statistik menggunakan independent t-test dan menunjukkan perbedaan signifikan dalam perawatan pasien diabetes melitus (p=0,00<0,05) antara kedua kelompok. Setelah intervensi DSME, 75% responden dalam kelompok intervensi menunjukkan perilaku self-care yang baik, sementara pada kelompok kontrol hanya 56%. Analisis statistik menunjukkan perbedaan rerata self-care pada kelompok intervensi yang meningkat secara bermakna (nilai p 0,01), sedangkan pada kelompok kontrol tidak bermakna (nilai p 0,06). Penelitian ini menunjukkan DSME mampu meningkatkan perawatan diri pada penderita diabetes melitus
PENGARUH PEMBERIAN RHODAMIN B PERORAL SUBAKUT TERHADAP PERUBAHAN KETINGGIAN MUKOSA GASTER TIKUS PUTIH GALUR WISTAR (Rattus norvegicus Strain Wistar)
No full textLatar Belakang : Rhodamin B merupakan zat pewarna sintetis yang digunakan untuk pewarna tekstil, namun banyak disalahgunakan sebagai zat pewarna makanan. Hal ini sangat berbahaya bagi kesehatan karena Rhodamin B mengandung zat kimia yang berbahaya dan reaktif. Jika di konsumi dalam jangka panjang maka akan menyebabkan iritasi saluran cerna dan mengakibatkan gastritis.Tujuan : Mengetahui pengaruh pemberian Rhodamin B peroral subakut terhadap perubahan ketinggian mukosa gaster tikus wistar.Metode : Penelitian ini merupakan penelitian eksperimental dengan rancangan post test only with control design. Sampel berupa 24 tikus wistar jantan yang memenuhi kriteria inklusi dan eksklusi, kemudian diadaptasi dan dibagi secara acak menjadi 4 kelompok. K merupakan kelompok kontrol hanya diberikan makanan dan minuman standar. P1 diberi Rhodamin B peroral 3,5mg/kgBB, P2 diberi Rhodamin B peroral 7mg/kgBB, P3 diberi Rhodamin B peroral 14mg/kgBB. Setelah 30 hari dilakukan terminasi dan diambil organ gaster untuk dibuat preparat histopatologi.Hasil : Rerata ketinggian mukosa gaster pada kelompok K=987,054µm; P1=732,170µm; P2=587,187µm; P3=525,967µm. Hasil uji One Way Anova didapatkan perbedaan ketinggian mukosa pada semua kelompok (P < 0,05) dan uji Post Hoc menggunakan uji LSD didapatkan perbedaan yang bermakna pada K-P1 (P=0,009), K-P2 (P=0,000), K-P3 (P=0,000), P1-P3 (P=0,025). Tetapi tidak terdapat perbedaan bermakna pada P1-P2 (P=0,103) dan P2-P3 (P=0,479). Uji korelasi Spearman didapatkan hubungan negatif yang sangat kuat antara pemberian Rhodamin B dosis bertingkat terhadap perubahan ketinggian mukosa gaster (r=-0,781).Kesimpulan : Pemberian Rhodamin B peroral subakut berpengaruh terhadap perubahan ketinggian mukosa gaster tikus wistar. Semakin tinggi dosis yang diberikan, semakin rendah ketinggian mukosa gaster. Kata Kunci : rhodamin b, ketinggian mukosa gaster, perora
HUBUNGAN PENGGUNAAN ANTIBIOTIK DENGAN TINGKAT KEKAMBUHAN ISPA PADA BALITA DI PUSKESMAS CILEMBANG KOTA TASIKMALAYA PERIODE 1 JANUARI – 31 DESEMBER 2016
No full textSilka Reslia Riswanto1, Dyah Retnani Basuki1, Muhammad Fadhol Romdhoni11Fakultas Kedokteran Universitas Muhammadiyah Purwokerto ABSTRAKLatar Belakang: Antibiotik adalah zat atau bahan yang digunakan untuk mencegah dan mengobati suatu infeksi karena bakteri. Di negara Amerika Serikat terdapat 50 juta resep antibiotik yang tidak diperlukan dari 150 juta resep setiap tahunnya penggunaan antibiotik terus meningkat yang menyebabkan antara lain penggunaan obat yang tidak tepat akan menimbulkan banyak masalah segi efektivitas, efek samping, interaksi, ekonomi dan penyalahgunaan obat, sehingga memberikan banyak dampak negatif antara lain mutu dan pengelolaan pelayanan obat, resistensi obat, efek samping pada pasien, alergi bagi pasien yang alergi serta psikososial.Tujuan: Mengetahui hubungan penggunaan antibiotik dengan tingkat kekambuhan ISPA pada balita.Metode: Penelitian analitik observasional dengan cross-sectional, melibatkan 76 sampel dengan random sampling, analisis data menggunakan uji Chi Square.Hasil: Hasil yang diperoleh penggunaan antibiotik terhadap balita ISPA sebanyak 53,95%, balita mengalami kekambuhan sebanyak 46,34% dan uji Chi Square diperoleh nilai p value 0,004 (p = <0,05).Kesimpulan:Terdapat hubungan antara penggunaan antibiotik dengan tingkat kekambuhan ISPA pada balita
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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