187,415 research outputs found
Premessa. L'uso dello spazio e del tempo [Premise. The use of space and time]
No full textPubblicazione riportante gli esiti del Premio Architettura Emilia Romagn
Innovazione nell’analisi urbana per l’emergenza sismica - Innovation in analysing urban seismic emergency” (capitolo 4)
No full textAfter a seismic event, every installation undergoes physical and functional damage, threatening many urban functions present, yet it retains certain features that becomes fundamental in confronting the emergency.
These strategic functions may have been provided by a program of targeted measures, but sometimes they are inherent in the urban fabric that, over time, has become characterized by open spaces (squares, parks, gardens, car parks, etc.), wide streets, even buildings (historical or new) that are structurally capable of withstanding earthquakes and that can become strategic points of service in the emergency.
In analysing free spaces, connections or the structures created for emergency management, one also generally accounts for the system interconnection among emergency facilities and the accessibility to the local context.
The goal of planning an intervention system in anticipation of seismic events or the reconstruction process in the event of disasters must concern the reorganization of urban systems and the referred building, which should be considered in restoring both access systems to urban areas as well as those linked within the urban fabric, while the other side has to take care of reassembling functional, formal, infrastructural and structural buildings damaged and the possible interference with public spaces, in accordance with the urban system and construction and with the close relationship between the environment and urban landscape
Regenerative treatment using a radioelectric asymmetric conveyor as a novel tool in antiaging medicine: an in vitro beta-galactosidase study
No full textSalvatore Rinaldi,1,2 Margherita Maioli,1,3,4 Sara Santaniello,3,4 Alessandro Castagna,1,2 Gianfranco Pigliaru,3,4 Sara Gualini,3,4 Matteo Lotti Margotti,5 Arturo Carta,6 Vania Fontani,1,2 Carlo Ventura1,4,71Department of Regenerative Medicine, Rinaldi Fontani Institute, Florence; 2Department of Neuro Psycho Physio Pathology and Neuro Psycho Physical Optimization, Rinaldi Fontani Institute, Florence; 3Department of Biomedical Sciences, University of Sassari, Sassari; 4Laboratory of Molecular Biology and Stem Cell Engineering, National Institute of Biostructures and Biosystems, Bologna; 5Department of Information Technology and Statistical Analysis, Rinaldi Fontani Institute, Florence; 6Ophthalmology Section, University of Parma, Parma; 7Cardiovascular Department, S Orsola Malpighi Hospital, University of Bologna, Bologna, ItalyBackground: Beta-galactosidase is the most widely used biomarker for highlighting the processes of cellular aging, including neurodegeneration. On this basis, we decided to test in vitro whether a set of rescuing/reparative events previously observed by us in subjects treated with radioelectric asymmetric conveyor (REAC) technology may also involve antagonism of a marker of aging-related degenerative processes, as assessed by a reduction in beta-galactosidase at the cellular level.Methods: Human adipose-derived stem cells were cultured at different passages, ranging from 5 to 20, with or without REAC exposure for 12 hours. The cells were then processed for biochemical beta-galactosidase staining and morphological microscopy analysis.Results: We observed a significant reduction in expression of senescence associated-beta-galactosidase, and a persistence of fibroblast-like morphology typical of human adipose-derived stem cells, even at late passages.Conclusion: Our results indicate the ability of REAC technology to counteract in vitro senescence of human adipose-derived stem cells, and prompt the hypothesis that such technology may be exploited to antagonize in vivo senescence of tissue-resident or transplanted stem cells playing an important role in clinical treatment of age-related processes.Keywords: aging, adipose-derived stem cells, neurodegenerative disease
A scientific approach to the characterisation of the painting technique of an author : the case of Raffaele Rinaldi
No full textDuring the last restoration of the six paintings by Raffaele Rinaldi (1851-1916), located in the church of Maria SS. Annunziata (Marano Principato, Cosenza, Italy), made between 1890 and 1903, several scientific investigations were carried out on them. The present work aims at classifying the painting in terms of its materials and technical particularities. The goal of this study was to characterise the painting technique of the painter, its evolution and possible additions made during previous restorations. Pigments, binder media and raw materials used for the application of the ground and the paint layers were studied using electronic microscopy equipped with energy dispersive spectroscopy qualitative microanalysis (SEM-EDS), infrared spectroscopy (FTIR) and gas chromatography coupled with mass spectrometry (GC/MS). Furthermore, a complete analysis of the state of preservation of these paintings represents a scientific aid and guide for its restoration, taking into account the severe damage not exclusively due to natural decay processes. Our data can provide information about historical and stylistic background as well as advise for correct planning of the cleaning procedures. The identification of materials allowed a correct restoration
Mario Zaffagnini Architetto e Docente
No full textSi tratta del primo trattato scientifico in volume cartaceo che presenta la figura di Mario Zaffagnini, architetto e docente bolognese scomparso nel 1996. Considerato un maestro dell'architettura e del design, ma soprattutto uomo di cultura capace di lasciare tracce indelebili e a tutt'oggi di attualità nell'ambito sia della ricerca tecnologica che in quella della progettazione architettonica ed ambientale. Il volume, curato da Andrea Rinaldi e Zaffagnini Theo, si compone di due parti. La prima, aperta da un editoriale di Andrea Rinaldi, è dedicata a contributi critici di allievi e colleghi di Mario Zaffagnini. Tra questi si segnalano quelli dei Proff. G.Trippa, A. Acocella, G. Giallocosta, C. C. Buccolieri, A. Manfredini, N. Marzot, P. Davoli, M. Toni, A. Gaiani e M. Balzani. La seconda ad una ricca sezione di progetti e opere (alcune pubblicate e descritte per la prima volta) curata da Michele Ghirardelli e Gabriele Lelli.
Mario Zaffagnini, è stato autore di innumerevoli pubblicazioni scientifiche di valore nazionale ed internazionale che vengono pubblicate in un regesto esaustiv
Superamento degli ostacoli anatomici in chirurgia implantare, English.
No full text"Superamento degli ostacoli anatomici in chirurgia implantare by Rinaldi M, Mottloa A."--Title page verso.dental bookfair2016Includes bibliographical references and index.xiv, 552 pages
Offline INP measurements at Ny-Ålesund (Svalbard) in 2018
No full textThis dataset reports atmospheric ice nucleating particle (INP) concentrations, measured offline on samples collected at ground level in Ny-Ålesund (Svalbard; 78°55’ N, 11°56’ E), in spring and summer 2018. The ice nucleation properties of the samples were characterized by means of two offline instruments: the Dynamic Filter Processing Chamber (DFPC), detecting condensation freezing INPs, and the West Texas Cryogenic Refrigerator Applied to Freezing Test system (WT-CRAFT), measuring INPs by immersion freezing. Sampling for DFPC occurred on a campaign basis (one in spring and one in summer) with daily resolution and sampling time of about four hours, while filters for WT-CRAFT were collected continuously from April to August, with four days sampling intervals. Meteorological data from 15 April to 15 August 2018 are also reported. Meteorological parameters were taken from the Amundsen-Nobile Climate Change Tower, positioned less than 1 Km N-E of the sampling point.
This dataset is discussed in a manuscript titled “Condensation and immersion freezing Ice Nucleating Particle measurements at Ny-Ålesund (Svalbard) during 2018: evidence of multiple source contribution” by M. Rinaldi et al., which is currently under review for Atmospheric Chemistry and Physics
Industrial Policy and Artisan Firms (1930s-1970s)
No full textThis essay shows that after WW2 the Italian state carried out a policy for artisanship (that is, for the smallest firms) of an extent that was unparalleled in Europe. This policy was based on the provision, on the one hand, of lower taxes and and employers' contributions as well as welfare benefits at reduced premiums and, on the other hand, of 'substitutive factors': soft loans, srevices and promotional initiative by state agencies. Such a policy for artisanship played a twofold role: partly 'defensive', protecting a segment of marginal firms, and partly 'proactive', prompting modernisation and innovation of more promising firms. The latter were clustered especially in the industrial districts of the centre and north-east of the country, whose development turned out to be boosted to a significant extent by state intervention
M&A vs Organic Growth: Growth Strategies in the Eyewear Sector
No full textopenIl presente elaborato esamina le strategie di crescita nel settore dell’eyewear, focalizzandosi sul confronto tra la crescita organica e le strategie di M&A. Dopo una descrizione dell’azienda Safilo Spa ed un’analisi del contesto competitivo mediante il modello delle 5 forze di Micheal Porter, viene descritta l’esperienza di stage presso questa organizzazione, nell’area Finance & Accounting. Successivamente, viene analizzato il dibattito teorico ed empirico sui benefici e sui rischi associati ai diversi percorsi di crescita. La crescita organica offre maggiore stabilità e controllo, ma può limitare la velocità di espansione e innovazione; al contrario, l’M&A consente un accesso rapido a nuove competenze e mercati, pur comportando rischi elevati di integrazione.
Attraverso i casi di due acquisizioni di Brand, quali Blenders Eyewear e Privè Revaux da parte di Safilo, vengono evidenziate opportunità e criticità delle operazioni straordinarie. L’elaborato mostra come Safilo, adottando un approccio libero, abbia cercato di equilibrare la solidità derivante dai propri brand con l’innovazione offerta da acquisizioni mirate. Inoltre, il confronto con altri casi del settore, come la fusione tra Essilor e Luxottica, oltre alle acquisizioni di Kering Eyewear, conferma che non esiste un’unica strategia efficace, ma che la scelta dipende dalle risorse di cui un’organizzazione dispone.This paper examines growth strategies in the eyewear sector, focusing on the comparison between organic growth and M&A strategies. After a description of the company Safilo Spa and an analysis of the competitive context using the 5 forces model by Michael Porter, the internship experience at this organization, in the Finance & Accounting area, is presented. Subsequently, the theoretical and empirical debate on the benefits and risks associated with different growth paths is analyzed. Organic growth offers greater stability and control, but can limit the speed of expansion and innovation; on the contrary, M&A allows rapid access to new skills and markets, although it involves high integration risks. Through the cases of two acquisitions of brands, such as Blenders Eyewear and Privè Revaux by Safilo, the opportunities and critical issues of extraordinary operations are highlighted. The paper shows how Safilo, adopting a free approach, has tried to balance the solidity deriving from its brands with the innovation offered by targeted acquisitions. Furthermore, the comparison with other cases in the sector, such as the merger between Essilor and Luxottica, in addition to the acquisitions of Kering Eyewear, confirms that there is no single effective strategy, but that the choice depends on the resources that an organization has at its disposal
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