38 research outputs found
Electromagnetic susceptibility assessment of controller area networks
Mixed signal communication networks are used in electromagnetically noisy environment to establish a stable link between local systems. The ability to predict their EMC compliance to standard immunity tests in design phase is required. The paper focuses on an AMS modeling procedure allowing to describe the CAN bus behaviour when affected by disturbances. The network is simulated combining mixed-signal models of CAN transceiver, cables and noise injection circuits, correctly assessing at system level the relationship between analog and digital signals. The obtained model efficiently predicts the influence of a continuous wave disturbance and estimates the immunity graph obtained through standard testing in a design phase. An application example on a real CAN network concludes the paper and confirms its ability to assess EMC problem
Integrated Circuit Modeling for Noise Susceptibility Prediction in Communication Networks
This paper addresses an integrated circuit (IC) modeling procedure for mixed-signal immunity simulations of communication networks. The procedure is based on a gray-box approach, modeling (IC) ports with a physical circuit and the internal links with a behavioral block. The parameters are estimated from time and frequency domain measurements, allowing accurate and efficient reproduction of nonlinear device switching behaviors. The effectiveness of the modeling process is verified by applying the proposed technique to a controller area network (CAN) transceiver, involved in a direct power injection (DPI) immunity test on a data communication link. The obtained model is successfully implemented in a VHDL-analog mixed-signal (AMS) solver to predict both the functional signals and the RF noise immunity at component level
Naissance d’une coopération dans un ESAT : quand des moniteurs d’atelier, un travailleur et un chercheur apprennent à travailler ensemble
La question de la place accordée aux savoirs fondamentaux (Lire, écrire et compter), pour des adultes en situation de handicap intellectuel, reste une question vive dans notre société où l’écrit est omniprésent. Dans cet article, nous allons décrire et analyser les premiers pas d’une coopération entre des acteurs d’un collectif, engagés dans une ingénierie coopérative (Sensevy, 2011), dont les champs de pratique sont a priori éloignés : des professionnels d’un ESAT (établissement service d’aide par le travail), des adultes en situation de handicap (appelés travailleurs) et une chercheure (l’auteure de cet article. Plus précisément, nous répondrons aux questions suivantes : que se passe-t-il quand des acteurs de cultures différentes apprennent à travailler ensemble ? Qu’est-ce que cette coopération inédite transforme ? Pour ce faire, nous nous centrerons sur la coopération dans l’atelier restauration de l'ESAT, entre un travailleur, Walter, les monitrices de cet atelier et la chercheure. Ensemble, ils vont élaborer un outil d’accessibilité, appelé cartes-constellations, permettant à Walter de mobiliser le comptage dans son activité professionnelle.For intellectually disabled adults, the place of fundamental knowledge (reading, writing and counting) remains a live question in our society where writing is omnipresent. This article is a description and an analysis of the first steps of an cooperation between members of a collective committed in a cooperative engineering (Sensevy, 2011) of which practice fields seem at first view distant from one another: staff in an ESAT (Etablissement Service d’Aide par le Travail: institution for help to disabled adults through work) adults with disabilities (called workers) and a researcher (the author of this article). More specifically, we will answer the following questions: what happens when actors from different cultures learn to work together? What is this new cooperation transforming? To do this, we will focus on cooperation in the ESAT restoration workshop between a worker, Walter, the instructors of this workshop and the researcher. Together, they will develop an accessibility tool, called constellation cards, that will allow Walter to mobilize counting in his professional activity
Radioactive Art
Radioactive waste can remain dangerous to humans for 100,000 years. Nations with nuclear power are building underground storage facilities to permanently house it, but how might they mark these sites for future generations? The nuclear industry is turning to artists for creative solutions. How might artists create a warning that will still be understood and heeded so far into the future? Radioactive Art meets artists whose work deals with issues around nuclear legacy, and visits the nuclear agency in France that has sought their input.
Presented by Gordon Young and Produced by Beatrice Pickup.
With contributions from:
Jean-Noël Dumont - Memory Division at ANDRA, the French nuclear agency
Stéfane Perraud - Visual Artist and creator of the 'Blue Zone'
Aram Kebabdjian - Writer and creator of the 'Blue Zone'
Mari Keto - Art jeweller and creator of 'Inheritance'
Erich Berger - Artist and creator of 'Inheritance'
Ele Carpenter - Curator of the Nuclear Culture Project funded by the Arts Catalyst and curator of the 'Perpetual Uncertainty' exhibition at the Bildmuseet in Umeå, Sweden
Richard Edmondson - Operations Manager at Sellafield Ltd
Tim Hunkin - Cartoonist and Engineer, owner of Novelty Automation in London
RFID equivalent model for prediction of functional and EMC performances in complex aeronautic environments
Louis Pasteur's three artist compatriots—Henner, Pointelin, and Perraud: A story of friendship, science, and art in the 1870s and 1880s
Author Correction: Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants.
International audienceNo abstract availabl
Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase
eEF2K [eEF2 (eukaryotic elongation factor 2) kinase] phosphorylates and inactivates the translation elongation factor eEF2. eEF2K is not a member of the main eukaryotic protein kinase superfamily, but instead belongs to a small group of so-called ?-kinases. The activity of eEF2K is normally dependent upon Ca2+ and calmodulin. eEF2K has previously been shown to undergo autophosphorylation, the stoichiometry of which suggested the existence of multiple sites. In the present study we have identified several autophosphorylation sites, including Thr348, Thr353, Ser366 and Ser445, all of which are highly conserved among vertebrate eEF2Ks. We also identified a number of other sites, including Ser78, a known site of phosphorylation, and others, some of which are less well conserved. None of the sites lies in the catalytic domain, but three affect eEF2K activity. Mutation of Ser78, Thr348 and Ser366 to a non-phosphorylatable alanine residue decreased eEF2K activity. Phosphorylation of Thr348 was detected by immunoblotting after transfecting wild-type eEF2K into HEK (human embryonic kidney)-293 cells, but not after transfection with a kinase-inactive construct, confirming that this is indeed a site of autophosphorylation. Thr348 appears to be constitutively autophosphorylated in vitro. Interestingly, other recent data suggest that the corresponding residue in other ?-kinases is also autophosphorylated and contributes to the activation of these enzymes [Crawley, Gharaei, Ye, Yang, Raveh, London, Schueler-Furman, Jia and Cote (2011) J. Biol. Chem. 286, 2607-2616]. Ser366 phosphorylation was also detected in intact cells, but was still observed in the kinase-inactive construct, demonstrating that this site is phosphorylated not only autocatalytically but also in trans by other kinases
