6 research outputs found
Comparison of two heparin-coated extracorporeal circuits with reduced systemic anticoagulation in routine coronary artery bypass operations
No full textAbstractObjectives: The use of heparin-coated circuits for cardiopulmonary bypass attenuates the postperfusion inflammatory response. Postoperative bleeding and the need for allogeneic blood transfusions are reduced, particularly in combination with lowered systemic anticoagulation. The two most commonly used heparin-coated systems are the Carmeda BioActive Surface (Medtronic Inc, Minneapolis, Minn) and the Duraflo II coating (Baxter Healthcare Corp, Bentley Laboratories Division, Irvine, Calif). The 2 surfaces are technically unequal, and previous experimental studies have demonstrated disparities in effects on the immune system and the blood cells. However, no larger comparative studies of relevant clinical end points have thus far been reported. Methods: Over a 24-month period, all patients undergoing coronary artery bypass were prospectively randomized to one of the two heparin-coated circuits. Altogether, 1336 consecutive patients were included. The heparin dose was reduced in all cases, with an activated coagulation time of more than 250 seconds. Clinical data were consecutively collected and stored on a computer for comparative analyses. Results: There were no statistically significant differences in any demographic or operative parameters. The Duraflo II patients required less heparin to keep the target-activated clotting time, confirming the previous finding of some leakage of heparin from the surface to the circulation. Otherwise, there were no significant differences in time for ventilatory support (Duraflo II, 1.7 ± 1.3 hours; Carmeda BioActive Surface, 1.6 ± 1.0 hours; P =.37), amount of postoperative mediastinal drainage (Duraflo II, 665 ± 257 mL; Carmeda BioActive Surface, 688 ± 243 mL; P =.07), need for allogeneic blood-plasma transfusions (Duraflo II, 4.2% of the patients; Carmeda BioActive Surface, 4.4% of the patients; P =.93), or hemoglobin concentration at hospital discharge (Duraflo II, 120 ± 13 g/L; Carmeda BioActive Surface, 119 ± 13 g/L; P =.08). The effects on renal function and platelets were similar, as were the incidences of perioperative myocardial infarction (Duraflo II, 1.5%; Carmeda BioActive Surface, 1.5%; P =.96), stroke (Duraflo II, 1.3%; Carmeda BioActive Surface, 1.2%; P =.47), and hospital mortality (Duraflo II, 1 [0.14%] patient; Carmeda BioActive Surface, 3 [0.45%] patients; P =.31). Conclusions: Despite differences in technology, complexity, and effects on biologic markers, no clinical differences were observed between the Carmeda BioActive Surface system and the Duraflo II coating after coronary artery bypass operations. The overall clinical results were favorable in both groups, confirming the safety and feasibility of routine use of heparin-coated circuits in combination with reduced systemic anticoagulation. (J Thorac Cardiovasc Surg 2001;121:324-30
Cold blood cardioplegia versus cold crystalloid cardioplegia: A prospective randomized study of 1440 patients undergoing coronary artery bypass grafting
No full textAbstractObjectivesA large number of experimental studies have indicated that blood cardioplegia might be superior to crystalloid cardioplegia for myocardial protection during ischemic arrest. However, no prospectively randomized studies of large patient series have been undertaken to prove potential differences in clinical course.MethodsOver a 52-month period, all patients undergoing on-pump coronary artery bypass operated on by 2 surgeons were prospectively randomized to receive either cold crystalloid cardioplegia (group C) or cold blood cardioplegia (group B) during aortic crossclamping.ResultsAltogether, 1440 patients aged 37 to 89 years (median, 66 years) entered the study (group C, n = 719; group B, n = 721). The groups were comparable in all major demographic, preoperative, and operative variables. The clinical course turned out to be nearly identical for both groups. No statistically significant differences were seen concerning spontaneous sinus rhythm after aortic declamping, use of inotropic drugs or intra-aortic balloon pumping, postoperative ventilatory support, bleeding and rate of allogeneic blood transfusions, perioperative myocardial infarction, episodes of atrial fibrillation, stroke or minor neurologic dysfunction, renal function, infections, physical rehabilitation, or mortality. Also, in subgroups of patients at higher operative risk (female sex, age >70 years, unstable angina, diabetes, emergency operation, ejection fraction <0.50, crossclamping time >50 minutes, and EuroSCORE >4), no statistically significant differences could be demonstrated between the groups.ConclusionsThere were no significant differences whether myocardial protection was performed with cold blood cardioplegia or cold crystalloid cardioplegia during aortic crossclamping in patients undergoing coronary artery bypass grafting. The extra costs related to blood cardioplegia might be saved
Heparinized cardiopulmonary bypass circuits and low systemic anticoagulation: An analysis of nearly 6000 patients undergoing coronary artery bypass grafting
No full textObjectiveHeparin coating of cardiopulmonary bypass circuits reduces the inflammatory response and increases the thromboresistance during extracorporeal circulation. These properties enables a lower systemic heparin dose, which has been shown to reduce the need for blood transfusions. Experience with this technique accumulated over 11 years has been analyzed.MethodsAll patients underwent on-pump coronary artery bypass grafting with heparin-coated circuits. Apart from some patients receiving a high intraoperative dose of aprotinin, the systemic heparin dose was reduced, with a lower level of an activated clotting time of 250 seconds during extracorporeal circulation. The overall strategy aimed at a fast-track regimen, with early extubation, minimal use of blood transfusions, and rapid postoperative recovery.ResultsAltogether, 5954 patients were included; 1131 (19.0%) were female (median age, 70 years), and 4823 were male (median age, 65 years). The median additive EuroSCORE was 3 (range, 0–14; mean 3.5 ± 2.5). No significant signs of clotting were seen in any part of the extracorporeal circuit. Bank blood products were given to 427 (7.2%) patients. Median extubation time was 1.7 hours. The stroke rate was 1.0%, transient neurologic deficits occurred in 0.7%, and perioperative myocardial infarction occurred in 1.2%. On the fifth day, 88.1% of the patients were physically rehabilitated and ready for discharge. Thirty-day mortality was 0.9% (54 patients).ConclusionsThe experience with this patient cohort including mostly low- to medium-risk patients with a relatively short cardiopulmonary bypass time indicates that coronary artery bypass grafting performed with heparin-coated circuits and reduced level of systemic heparinization is safe and results in a very satisfactory clinical course. No signs of clotting or other technical incidents were recorded
Author Correction: Risk of hematological malignancies from CT radiation exposure in children, adolescents and young adults
No full textInternational audienceIn the version of the article initially published, Magda Bosch de Basea’s surname appeared incorrectly (as Bosch de Basea Gomez) and has now been amended in the HTML and PDF versions of the article
Risk of hematological malignancies from CT radiation exposure in children, adolescents and young adults
No full textAuthor Correction: Risk of hematological malignancies from CT radiation exposure in children, adolescents and young adults : 10.1038/s41591-025-03689-5International audienceOver one million European children undergo computed tomography (CT) scans annually. Although moderate- to high-dose ionizing radiation exposure is an established risk factor for hematological malignancies, risks at CT examination dose levels remain uncertain. Here we followed up a multinational cohort (EPI-CT) of 948,174 individuals who underwent CT examinations before age 22 years in nine European countries. Radiation doses to the active bone marrow were estimated on the basis of body part scanned, patient characteristics, time period and inferred CT technical parameters. We found an association between cumulative dose and risk of all hematological malignancies, with an excess relative risk of 1.96 (95% confidence interval 1.10 to 3.12) per 100 mGy (790 cases). Similar estimates were obtained for lymphoid and myeloid malignancies. Results suggest that for every 10,000 children examined today (mean dose 8 mGy), 1–2 persons are expected to develop a hematological malignancy attributable to radiation exposure in the subsequent 12 years. Our results strengthen the body of evidence of increased cancer risk at low radiation doses and highlight the need for continued justification of pediatric CT examinations and optimization of doses
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No full text?
^wUyfirlri
tS-nferprijSt.
PI HLJHllEn KVKItY BATIRDAY;
— AT— ■'
Mayflela, Santa Clnrr* Caarsty, Ceil..
-It-
W* H. CLIPPERTCN.
Trrma per annnm (in advance)* tM 00
"4a months ? SO
a-M-at t w
1NISZAX TROT DLLS.
The Indiana are again on the wnx
path, ami the pulley v,-_tb reference to
them f*e_nis to by e-xtcnm.mtic.n, Fa_
better would it hi.- to redress thfflr
-arrnngs, nnd huVe little or no trouble
with them. Thr-y ones possessed this
v&at country, and, as the first inhabi-
tuntra, hud ft prior right to select the
nmonnt of land they-actually needod,
and wherever thfyplensed. They have,
however, Iwvcn treated with tho greatest
injustice. Tho enrly acttlera r.*cog-
nui tl only tba rij-ht of the t-troiige-it,
or bought the l:u:i. nt n nominal price.
•Vs-Jr. PrintInc ft eviry detv*rlptIon ex-,
sated with ne-lnr*s and dlhpcteh, end nt San
rr*aeisco priecA.
Ts Ait-*ertl-er-.-Th* "***™**™S
htitttm •tar-rterwllhsli-rj-i- suu-<*ript'en 1th*.
and rlrrnl'.e- ehlefly en villi the Vttv l-.t
ebttwof nt**lcTjT>erti fur T ■ imi*res* tn-n—.-thrifty,-,, , -
-*--_a__fsrt-t_Bmoniry. The fnm-.i*.t'»n "f i-ry rhcir dewendauts have put tho Xrnh-
mmmar*t- "-**" ***" U'd ** juJK"ii:lut adT<"T'j-~s ou wJ__l_v-r.rowrA*^Jui. they
VmWm*^*f- . Iplctiscd, nnd nflerwaulH Relflr-lily nnd
cuprieioUMly moved them ftwnv*, totally
diRrc*j*7iTdliig nnd ignoring the fnith .if
treaties. Tho pension-, vrliich bribe
them to submit to this injustice do not
always Tench them; many of their Supplies are Hold by dishonest ngenta to
equntly ajuhoDe-tt troders, who get them
for n:*.eh lc*« and sell them for much
more th.in they tat worth, Boon ttcrap-
Ing together a fortune. The wond*r is
a_^_^_^_^_^_^_^_^_^_^_^_^_^_n_t i--ot that they tnkc the ivtir path, bnt'
on n par with Indiana, which ttnvs little ,_ _ ... .,
_T, "^ . . «,_ .. , _r . Ihnt they have not taken it sooner.
*-__.*ww. awvial llf*. ■—*• lha it, ft we, 1 ct-.tr*.- r-vr* t -
Unman nutnre is the same cverywhert'
and there is a limit to patience and
I* F. Plslier ts onr author!--.1 c*jent at
Ssa rrsntrlrieo.
SATURDAY. MAY "Jst 1B70.
-MARRIAGE AND DIVORCE.
The new divorce law puts California
far ita social life or the moral atarns of i
ita inhabitants. Divorce implies either
that parties wish to encftpe the evil*
into which their imprudence has led
them, or that they tnko thia means of
gratifying their love of ehange. Jn tho
first esse people abonld tnhc care not
to enter into the marriage contrnct unless they have good nnd anffieicnt rrn-
aona for believing that theirs in the
mutual reeognitinn ot a roj.lii-nl ideal, 1
aad that human foresight canrjot po*.
aibly anticipAte a divorce. Of ctirrrse,
howpver, this ia a matter of taste: some*
prefer excellence and pernmiiencc;some
OF7ICIAX. PATROXAOE.
... ,.. a a- . ... '__ *A- I »tl«»l|J. lunar, fl 111.- UIUUJU llil,
like to grutif v fuucv, nnd free thrtcr-cl veal . , , , ., 7° .
** * , , . -. , constant focts of the Amonsaas, -..1..
whenever thev plcaFf. from the bonds ..... -> , ~. . _
■*--%- f that Iho Red River insurgents ennuot
v-Ma-ti Hani- *-a*w»_--_- _e,Ti»t ifi* tl,.,r in. I
forbeninnce. FoUtiduna who wont
the Irish: vote will nive ubont tho-wrongH
of the Irish, Imt will not say n word'for
the Indian, 'nieymnyf-nytliattheinter-
csts of civiHi-itiun require that the superior race ahonht take tho phicc of the
inferior, but their encouragement of
Chinese immigration given the lie to
any Mich assertion. There muHt be In-
tlion troubles till the Indian* cither get
cxitct jiisiice or ale pxterniiniited. Tho
fact that the Indinus are gi'iiemlly the
strong allies of tbe Engli-n. nnd the
and
-which they anppos-. sanctify their fn-
tercourae; others fpotiSy fancy without
any auch bonds or hypocrisy. N.-bonda,
no ceremony, enn sanctify th-- motives
for which some people enter into the
marriage cot.trr.t-t, when they sell thczn
h«1\cb aa really nn others do without
aay each contract, the mond conac-
qnencea of which nre equally degrading, althcugh convent io*-"! aham decorums imply otherwise. The childn>n
ot this woild aro in their gmeration
wrser than the children of light: by
bt-ing less scrnpiilons they can rocoe-cd
better; but, by a mad short -sigh tedner-s,
they sell thcm-clvca and (heir birthright in the grent and glorious future
for ii mess of pottage iu the present.
Marriage, as oMained by God, has
refereiice to a future a well na a present, and is based on tho principle of
luutiinl help in the grai d uuwurd nnd
upward march now and through the
ages. When two pcoplo of diutfent
. sexes so underr-taml it, and i-t 1 that iu
ttttch a relation they ore - < rfectly suited
to each other,—when if tbey discarded
mercenary, and other low aud unwo.-thy
motives they would nnite snd assist
each other,—then in everything concerning spiritual affinity and congeniality of mind and pm-poise.' God lias
joint 1 them together. I-«_t not man
join those together whom God hath not
joined—whos*! t*-T_clious ftre not intertwined or are fixed clse-w. tore, or who
tucll themaclves its a matter of present
convenience. Those whom ninn joins
together by cither n religious or a civil
rnutract he will often have to put
ii^iUhkr' the wrong is not so ninch tu
putting them aaundcr as ever having
joined them together. Msrriage should
!■» batvetl more on Ihumonil thin on the
}a-<umary' help lo bo derivtd from snch
ijoutract mid uuion: the great ossctriii-l
W aiti-h esse is right principle, which
<tui be relied on, and which will Inst.
People who do Dot know wh-it pritu-i-
plo is cannot diatiiiguish it in others,
and therefore c.m have no basis for n
sensible choice: the consequruceia that
obtain usinglo recruit from tho mane
Indians who nro i-.iving tho United
States ao much trouble, nrguca a far
different trt-atiueut of them by tho two
peoples nnd governments.
e*w4* ,— ■
[Commtinicetcdd
VEr*TIl_ATOU ON WOMAN StTF-
FHAGE.
Tho advocalt'3 nf woman suffrage
iimke much of *ho ussertian thnt "Governments derivo their just powers from
the consent of tho governed." I will
assert that neither ihe will of (hegovern-
ment nor the consent of tho goverued
can make that right which Vh wroug, or
make that just which is uuj-.tcit. Jef-
fersou is s-ud to htve bjeu an iu>ldcl;
be that as it may, those who maku the
Di.cLir.Ui-ja of Iu,l.--iv:i I 'ii.-- their
Bible, and put the consent of the governed before iho HUproinit majesty of
right und the author of right, havo it
tendency toward iufldt*lity, Tho hiw i -
a terror to evil doers, who only arc actually governed. We do not ivik their
consent bof.tro compulling them to respect the rights of oth-ra, aud whether
society gives its coniwnt or not, it is
every mnn'sduty to battle for tho right.
Wc have a future before uo iu which
our Rtatc will depend on ai.uil.ir conditions to what it docs now. Intensity
of right th mght and feeling, and a
steadfast adherence to aud l.vu of tifi.
good nnd right, will produce happiness;
tho reverse,. misery. Iu thj gruuu
onwtuxl and upward march toward
general amvliomtiou, progrv**-djn and
improvement, very mnch dupeuds on
tho friendships wo contract,, but f**r
mora on those to whom wo arc united
by the strongest ties. At tlie same time
that we anticipate and prepare for u
failure, we ennu >t with impunity neglect the requirements of the present,
and It- atteiiiling to mattern behmgin;*
exclusively to thi* world, wo sre too
apt to injure otirsolvt-** with respect to
tho future. Docs nny ono not devoid
1 of hopes and nspinitions wish the one
4h*y be*?ome allied, not united, with I uv -1,veB ■*e,t -•- 8° --»ngh the twme
^^^^ 1 ordetis be « subjected lo in Ifac strnggle
j ft»i* life, nnd attCVr nnd retrogrndt- like
■viiio.i.ipfi'cni tnY-^-wi6*V».'' People
•sill marry fooh-hly and take great risks
Ijecauae they easily get a divorco. In
tho U'ginmng it was not so, nor will il
ever bo Biv«xcept on account of the
iguoiunoe and depravity of hnmau nn-
ture. Divorce ahould be the rare ex-
rBption, not the goneral mle\ but no
long oa people idly tii-V-tactvcs In the
r they do, Ihrn* wilt U'/i-etjucut
in which auch t-lbnoicto will se
hniksiL 1'ooli-h fancy, bastd on uo-| ■*-»'**v -he risfet, aul foolishly think she
tiling, is no good aud snflkient reason can •■-■w benefit h,r husband without
for iiAt-rriurt*, or cvL>aio«nd»bip. any potsible chsnctf of injury to her-
Thoao who uumy for mt rcemuy uud j **»'* H|l(t ***- Pr(-,Te *» truer helpiuute in
tOwWr low and unworthy motives, do Another way. It is well for n man when
thatonlettso which others, whom they wearied with the Mrcs, and disgusted
_-ue<*t to gaze on with horror aud dia-! w**h nnnoyatwea nnd tbe evil he Iras
gust, do withotsfi
*i iittlm ot Atut rlcs I lx*u«Iit snd cold
tor the prld- of place and -bu luat of gold!
vThlU* IBe. hrav.-ru. loc* tn and wo_dt.r
Think ef the Vlljlittd sad waat..I lir.a
Uf fc-li-h b-ab*tiila and Ul.aurr.il -.ire.n
Slxn has tu put a-AiuiU r.
trOSi th-m by the Msrthaa who ar.>
careful and trottbled nboat many things.
Va*miuTOi!_
'•MRHORIAL DAY."
TbeaTtOth nf slay ia established the
" Memorial day" of the nation. On this
day lha graves of "onr fallen" will bo
d-x*****ted — th* taat- resting place of
those tmot hving and brave! Full of
Ills, IVill of uudinching courags they
marched to the tight awl gave up H'eir
lives! Each aohlior now at rest, had j 4.^
haa tate-real*-, loves and him*,—:tll hud _ _, <__^__^__^__^__h
__. --.v. ,,, _ , * linos performer* ever aeen on tho cowl,
down wtih hta life, forjh-ut ronntrv he j ,,. -____ . .. , » , ,-
v_^-m— ., ^ um-j.Aj^ljj,,! that ho and lit* son,
Istad so ikarh: It -a*raa no tntle to j
taaa** heave ones thna to be cut off from ]
It matters not whether on aristocracy,
a democracy, or a moliocrncy is vested
•>vith"patrouiig'>, if tho same is abused:
Those Institutions are the ftrat-i.ypi.ist-
-li-e where there is thee'l.-ast pt sut^
ab*.isc, altlnuijh they nray not "be my
jacar perftrtion in theory, that.rlfrht
appoiiitments should be mii.de*Tsof far
more importnncc than tho question of
who shall hare the appointment. It
n and o mmirntary tm the purity of republican iDstitutiona wln.-n aspiring
demngogues aud dishonest politicians
hold sway, mid person-tl friendshlpeven
takes ]Wocc(leuce of the public good
The abuse of pntn-nage is far greatt r
when one man is removed to mate
room f*r another, an iujnstiea being
done to the ono in order Out n. favor
may bo done to the other. The removal of Coloiifl James Coey, Postmaster of Sun Francisco, ir a mr*nsurt.
wh'ch cannot be justified without proof
of incompetence or maladministration.
If a man wishes to do a charity to a
trie-id or ft parasite, he can honestly do
so out of his own pocket, and not
otherwise unless he recommend him to
some charitable individual or institution. The public business ia ono thing
and charity is another.
■■■ ■ * ■■- •*■+■•*- ' .a—-■
xnvs iti:-is.
....Further accounts, from the Indian troubles in Colo-**ado are received.
Tho Indian:-,, supposed to be Cheyenne*, attack in parties generally from
five to ten. At Like Station, where
they attacked five Mexican trains they
were two hundred strong. In this
fight several ludinus were killed nnd
threo wounded. At Wi low Spriugs
IwOiniro's Mexican train was nttuckod,.
seventy miles from Corinne. Thoy
li-st one man killt-d. Two miles west
of Cnrsou thirty mules were captured
find one nun killed.. Eight miles west
of this, Mr. Dudley, an engineer, was
killed, and his tenia captured. XSear
tho same placo another party had a
fight, two men were killed mid one
wounded. Several other fights - are
reported, with similar loss. . The total killed will probably amount to
twenty, names uukuown, besides many
many men mi-tsing.
The M irysville Appeal iu notice-
ing tho show of the " Living Won
d..rH,"_ays that the beautiful Circassian denies tho ropuri in a >*•..■ 1 •. 3 ..-
per th-it sh. had married. All wc know,
about it is thtt a li.-<. :■ ■ - was issued by
tho Clerk t_ the parties mentioned.
R.v. Mr. Stnmp performed the usual
ceremony and returned a certificate to
the Clerk, where it is now on record.
Moreover Miss Luti Huso and C. -J.
B.-istle o.._np-ed tho samo room the
ni^-htof the purported mirrhxge; there
wiw but one lied in that ronm und the
chambermaid (who did not know of the
marriage) says two persons fllepfc in
that bed. If thoy are not married they
should be.
.. It is now certain thtt General
O'Ncil, Presilent of th_ Fonlatis, in*
teiiits to eo-operate with the Red Rivet-
rebels. He leaves for the West shortly,
to air.ange details.
A'flrm in Cincinnati- his f rec-ivtil
orders for thi mannfacture nf 8,000
hand gren-idts, for whom no one
knows.
M my rnmin nT» afloat re-jnrding the
d-'partnre . from the city, by various
ra-mtes northwest und west, of parties
of men supposed tb ho .Feniani. Undoubtedly, from the best authority that
c.m bo obtained, sevctfrd hundred men
connt**t*ted with Fenian organizations
have left th<? city, on the war-path.
G. A. Brier, editor of the Shor-
nmntown Jlepnrt'r, dropp* d dead in
theoffi-o of Wells, Fir^o *.-('>., at
Shermmtiwu. H*hrl bton sultering
for some d.iy*i with c*»ngestori of tbe
lungs, He will lw buried by the Fire
Department of Hamilton.
The President, nt the r>t**rsita-don of
Senator Cole, _ttt withlrrts*;i Coey's
nm*j nnl ni-ninitel _f. B. Stone*Ibr
Postmaster of San Fran-dtco. Cole favors tho rem >ral of Citlector Briggn in
the Fourth R.svenne District, nnd tht*
ap'wintment of J. R. JI.trd-jnbergh.
.. .The receipts of the Go-.-t-rnment
for the quarter en&iug March 31st
were *J22i,8.'.7,Tll,1, ineludiu,,' tho previous bnlsuce In (he tre.isury of i?!*JS,
■W3.*..Ti; the eiponditares spare, $_0G,
OOy.O-D.
The clerks of tho Tn snry Department recently scut to California
with n large quantity of Govrrnrai-nt
fnnds returnctl with 31,340,0(10, including fl.lW.OOO oweclled notes— th'e
remnindt'r in specie. J
... .Tom Allen, who signs himaelf
" Champion of America, by penntf-aioti
of 5I-. James M •■*. . Cbtunpion of the
World," has i-wnetl n challenge to all
profossiou.tl bruiiers. except Mace aud
bns receive.1. In this rt-speM- with ! 1','t?n'-n- *° -*^i: f«f 35.1W or less. He
iM>JV-tMW-tr^ pnrticnlarty anximit that Cubarn
nnd herejrftnwth,. Mtrys who c*ooaa j *^'J ■»',',_Trt'_ Allen admits dt-fcat at
the better pnrf ili'inld not httvc tt taken
THE GREEK BRIGANDS.
From an exchange we obtain the fol-
i lowing ]>,n truulu** of the capture by the
(.reel- bri-^tndt cf a.pairty of eight per-
so>is, consisting of Lonl and Lady
Mincuster, air. Frederick ■ Viaer, Mr.
i Hvrbert, the _4irqttls*'d- -.-ryle, and
' M.-. nnd-M.s. Lloyd, -sTtth-'tlsa-r UtUe
daughter: ■* 5f ' * ■
These persons, sedu_e<ftiy Ihe plens
ant weather, and moved and instated I
,.n,l«W.r by U.e -ttrpasetas .albtt'*, of) tnt-^. mTLm'milot'i^SStSS
i'Atlicns-it*3tf^sUrtiiK; -i - | y^,,*?^".! f***1**-^ ^ir^oi» .. tn.:.!'*
Oh their way out tbey f* imtl tbe road ] ui
pal
KEW ADVirRTISEJIENTS.
SPRING ARRANOEMENT,
S. F. & S. J.
Santa Clara and Pajaro Vall«)r
11 "*■J *?Tt ° A J>'
mf\W AST, APl-K SIUXOAY. Al-ftn.i.tpf),
•tsl. -MC,Io*k AM ,,*'-,il t-«h-.r notice),
.-I-reln- will licvt. na follutr-:
WEEK DATS.
1. ana ...0 p. iu.; Ueulo'rartt, U:io s. ra""
*■■*»*,■*:« p.m.; m j a. 1.1. Vtil a.m., a-o.
_^^M_
-Corinth, over which the mails nnd pas- I *,** * _ (**: «>«>*wyA)at>_i_ta 11. in", at lt:*t>
. . ■« ' ■..,' . - - •-j _ "■m -*11** V'A*P m.—arriviujal Oilx-rat U-JO
sengere by tho Greek basts from Corfu ■ s. in. snd * - - »-•*_•* *---i-_y« *i--j
aro regnhtrlr trn'hspWett. -fb-&ugget**.[ ..f^^fSr , #1_ „, „
_, _ J_* . f^ _^ |.a-,_ -e.rTwe.e-1 .. * * .^ " J'*°**..*!l"i'.HOBST, t**^*> S. IB..
him by Attrition with tho rougher elements of humanity? W;»„ld not ft man
rather prefer that ahe shoull be kepi
from everything which'w.mld injure
her liner feelings an*l blunt bn scusl-
bi'ittea? Ono of tficm must take the
risk; the other Ins far more cause for
thankfulness"Hban for envy. The woman miiy, however, unKeltishly wish to*
met with during the day, if n gentle
spirit who ha*kept sloof from tho (Torst
phases of life can soothe his troubled
feeling*, and can by tha sympathy and
love of a -refined and elevated imtrtre
neutrals.-:-' to SJLTale) extent the injury he
narrows, and i. male a t-rifls gloomy by
a thick, ulo*o growth of wood and uu-
j d.'rl>.'u-h. Here,, without a sign or cry
ofwnruing.11 volley of. musketry was
pouretl in npon thefn, emptying t;vo
of tho sadtlles of thy, escort. The gentlemen of the party were mwrmed, having thought it best not to'alarm nhu
1 idles by what they coajiden-da -A-fc*a
display ot wen* on**, Had they been
provided with revolvers, it is quite possible that tho rttory of tho day might
have been very different. '
In a moment ill- .-ariiagcs were surrounded aud til ■ (..'■•!ip.i!its.l:_ii^-*id out.
Lady MuiACustcr was atruclc o.*er th.-
shoulv_L-re with a stiek by one -T-Cian,
and tho child of M s. j-iojd vi,)leutiy
thrown to the grouud by aui»tlr.rt.
It being esteemevl nuprofes-ioual bi
Greek biigandH to carry off women—
as women nre likely to succumb to the
fatigues of ft forced march, nnd so cannot be regarded as an investment promising r_manenitive ransom—the Lidies
were dispatched to Athens after 11 shcrt
delay. , ■ - ,-
O.i the noxt' day tha captives were
nT-,\t~rni-rjTT of a »-neeisl Act of Lrgl-la
tt-reaft-v* SUte of &lUta-a-s, appr-ivej "Ptb-
UBrvpta. lS.O, tbe Tru*U-s of tbe J-rrcafi.
tLIi-Ij-fcrajy AK.«>c!_tl<jn a_ve the plea--_re lo
thai a
GRAND GIFT
COVERT
llLii-n-iN., 1, -. v. Gilror at t*;10 a. m. -nU
^h^^^-^^^^^^^^^^^^^^» * -.4*tp a..: •!'«-, iitv-oii. ,-iitUHon -■-*^*-f-*--
tapn of tiingcr appears to have mairetl 'i-u p. m ■. KiKUt.i-s-Mlle Hiiiue. 7:*. *. m..
tb.fr pltTtstiro m iHh reneheil, on *^J J _• ^^- >__J*.*^j *.; _.;
theirar-jtarn. a noint on the sloi*oof lh«| '-:i<» v "UfiSau J.,**, at i--m s.tn., ":Vis. m..
- 1 V - — ■ - *. _- „. ■ * j aiiu,---.p'm : StitaClar.t.0:.*-i.ni..S-l-0a.iii..
lam.>■■;.■ -.ii.i-jntaiti of FeatollOlIS, «-*AWtllu..a.i:l_|r. m; _Lr_.ld, .:•»*■. ni„ oM.. and
iHB0t more lbs* eight -ita. tlttta*j^Ul_T--»i-M^-__l-5M
from the city. At this point the-road -aid .-*.>]* m ; btnM-uo. .-..;*.ia.,.:io*.m..
u:<\ ;:■»(, in.—arr.riicT at Kan Kra_i:!-v. at
a-.Aj a. in., lv;ni a. ut., -ud -*-••) p. In.
Sl'NDAV TRA1X*,.
Uov ■ S:;it Fr-Ut.-l-H.-uat .-.a) Mid 'I*0:"-la. m ,
■111 - : ii i>. ni,—tin. SteO lain, ti.r m-li train to
O.lrt.y.
IlsSivttfiSBfosaat -30a. n; . -■'•' p. m., *-:..!
-•»•' p ni ; ttilny-t l:»-p. fti.
t.\, Xur...ii,.,.J-.*Lr.,i oil tr..int. ni:.r-'.-il
UlllAt
it**" Pftf**t'n*-er trt.Ins fo rod frtim GHryy
make 111.- d. put tin i 1 ■■•- h ■ ; i • 1 Sati Jowu.
All . il.l a" Si. ...*. Illl. .-...I i'tdr- .-il.lt -Isjls't.
i■;:;.: .:ir t::.\:xs
I • - v* San I'.-t ::■ . ■ • at w-JO *. ra., and GUror
•lull. in.
Kx.ur.Ioii tlcfcrtuiitsn-dRfttithl-rsnttntooas
nndSiuiili.)-., 'i.■.'..-• 1 i-iuNi 11,11 ii tka '"•-
' v. :;.' -1 ■■■-;* 111. :: ■.-.-. tit I it :■■! I ■-.,'.;i,:
rut. it, (torn .-"•.« lr.tii-iww:
M..I:!..'. tl.lv-. v 11 M.'.t.--.. US'. Ii !::i ,:i!.
!..■■: Ltiiv.,'..I Cily. 1..5; M<nlo I'-r_ and
-l->.rt aO,y.; bi.i.t» CitU- and K-tt Juav -a.
H. M. xfeWHAIX. PrtiJidtiit;
1: i1. HAMMoNii. Nijtr.iiMi.: m.
IN AID Of THE
MERCHANTILE LIBRARY
ASSOCIATION
WllX HE GtVEX AT THE
-.eclmiilt'i Pavilion
Sa-t FitASri-co, C tLironvix,
* Tlnir-adny, Sept, lat, 1*10.
UiultT the .Ht<*-*ti.'t) of diitli-wlttbe*- arlltta,
■iidtmlrf-t-uijT **lt*ctli>*»f*rXr-atl-~* n-«at faror.
lie toasters.
pno*oit.\MME or t**ONcr_tT to
!!!:i;i:utki; ANNorxrr.n.
TiT.
EVANar, ESTABROOK & CO..
(Counly rndL-rta-trs.)
TJntlt*rt«Uei*tt Jt I "11 nilHiicrs.
Centntl DLn-k. Wist Stmt, BBLR JOSE.
rpUK rNDIT-^IONED HAVING BEEN
f|"HE
•',» ii!!., -I t'-.s:;iiv I t..! :t--A. r*. rt-fv-tt
fully -.nnouueu Im the punlic tltat tb y wilt
.' n.i.iu- tin- I u.l ri-hiit,- ii.i-in, -. Hi all its
_n.11. Ii, -,-t (ho <iliI t.t-i;d. and -tadu'lt a *slit**v
ot tin- puldlc pt.tr m-itp*.
C,isi*ii.utiy -.a ti.aid a fne Moc_ of Crxne.
-,_ - < Dniil 1; Cvt.'s Pijt-itt -I Ullle C.skvta -ud
rot|t*.-ti. fir my.-- not tunmu..! 1 n u...
*** t 1 L_', tu,lu,(f.-sL, .Ul... 11; aud
by 1j1, whj sh inkt be dep.tU.-d to vL»it
tht> capital aul :u 1 io a.yaa jfiaijnti for
tht) rau-io.u of the rest.
Then ensued 11 touching scene. The
Italian Maraui., da Boyle, M.*. H-.-rbert,
aul 31.-. Vyncr, una:ii:u.i.idy*>refJ3i:*.!
tj take part iu the lottery ofllVrty and
purchvicof life, on" the' grii;ind thai
tiicy were iin~u,irritiil men, who.iu f.iH*
involvctl uo such cruel riiks for oth rs
as 1 iy hi Idea la th.* dread dacisiijii fo.-
the families-of Mr. Jjjyd uud Lo.d
M '. 1 ■ 1 *. ■:■. !■/ th.-se, than, Iho t-L-c-
ti/j waa liuiilly made, each in his turn
'drawing a straw fr-»m the h.iud of Alexandra, the guide. Lord M-n.*i*>U-r
drew the longer straw.
Of thasu'ije-i'i-ut no^ofiatuins nolh-
ing really clear and trUstw.i.*lhy is yet
i.u..-.v;i. nor of th9ra.ison which fin.dly
d-temiiued iho G.*eck Gjvornnicnt to
diaphiy for th. first ilino a fatally impc-
t.toils determiuiitton not '* tu parley
w;ih baudil'i." V,*a ,t wo k:i).v is only
this—that tho brigand*-, who were aa*
pejtitrg tho urr.v.il of many tt-tasj laden
with the huge sum in gold exuetul by
them as th-* ji'ri.o of thj Hborty of their
captive.*, Wa-r- sad liul
