1,721,061 research outputs found
La gait analysis in acqua utilizzando sensori inerziali
Full text linkNEI LABORATORI DI ANALISI DEL MOVIMENTO DELLA FACOLTÀ DI SCIENZE MOTORIE DELL’UNIVERSITÀ DI BOLOGNA, È STATO MESSO A PUNTO UN PROTOCOLLO PER L’ANALISI BIOMECCANICA TRIDIMENSIONALE DEL CAMMINO IN ACQUA (GAIT ANALYSIS), TRAMITE L’UTILIZZO DI SENSORI INERZIALI (RIFERITI ANCHE CON L’ABBREVIAZIONE IMMU, ACRONIMO DELL’INGLESE INERTIAL AND MAGNETIC MEASUREMENT UNITS). I PUNTI DI FORZA DI QUESTO INNOVATIVO PROTOCOLLO SONO QUELLI DI SEMPLIFICARE IL SETUP SPERIMENTALE E RIDURRE NOTEVOLMENTE IL TEMPO CHE OCCORRE PER ESEGUIRE QUESTE ANALISI BIOMECCANICHE, PUR MANTENENDO ALTISSIMO IL LIVELLO DI PRECISIONE E ACCURATEZZA. È POSSIBILE PERFINO EFFETTUARE I TEST CON IL SOGGETTO IMMERSO IN PISCINA, DATO CHE I SENSORI POSSONO ESSER FACILMENTE IMPERMEABILIZZATI. QUESTE IMPORTANTI CARATTERISTICHE RENDONO IL PROTOCOLLO UTILIZZABILE IN MOLTEPLICI AMBITI APPLICATIVI E, IN PARTICOLARE, PERMETTONO DI MONITORARE OGGETTIVAMENTE I MIGLIORAMENTI OTTENUTI ATTRAVERSO PERCORSI RIABILITATIVI EFFETTUATI IN ACQUA A CARICO DELL’ARTO INFERIORE
Movin and Bonar scores assess the same characteristics of tendon histology.
No full textThe Movin scoring system and its validated modifications and the Bonar scoring system are used to classify the histopathological findings of tendinopathy. We compared the reliability of these two different histopathological evaluation scores of tendon tissue. Tendon samples were harvested from 88 individuals (49 men, 39 women; mean age, 58.2 years) who underwent arthroscopic repair of a rotator cuff tear, and from five male patients who died of cardiovascular events (mean age, 69.6 years). A piece of supraspinatus tendon that was not directly involved in the tear was harvested en bloc within the intact middle portion of the tendon. Using hematoxylin and eosin staining and Alcian blue, slides were assessed using Bonar and Movin scores. The intraclass correlation was 0.921 (confidence interval 95% 0.790-0.963). Movin's and Bonar's scores have a high correlation and assess similar characteristics and variables of tendon abnormalities
Kinematic characteristics of adults walking in shallow water using wearable inertial magnetic sensors
No full textEffect of short-term treatment with low dosages of the proton-pump inhibitor omeprazole on serum chromogranin A levels in man.
No full textBACKGROUND:
Measurement of chromogranin A (CgA) levels in blood can be used to monitor neuroendocrine tumors (NETs). CgA levels may also be elevated in several other endocrine and non-endocrine diseases. It is well known that drugs affecting acid gastric secretion can increase gastrin. Proton-pump inhibitors are extensively used but only a few data have been reported on their effects on CgA secretion.
DESIGN:
The aim of the study was to evaluate the short-term effect of low dosages of omeprazole (OM) on CgA levels and to sensitize endocrinologists to possible false positive values of CgA in order to prevent expensive diagnostic work-up in searching for NETs.
SUBJECTS AND METHODS:
Thirty-five female and nine male in-patients (18-81 years) were studied. Mild or severe hypertension in 20 patients needed therapy. Endocrine and metabolic diseases were diagnosed in the majority of patients. CgA levels were evaluated before and during OM therapy (10 mg/day, orally).
RESULTS:
Without OM therapy, CgA levels were 64+/-6 microg/l. Elevated baseline CgA levels were found in nine subjects. CgA levels were significantly related to age (P<0.001), creatinine levels (P=0.03) and the severity of hypertension (P=0.002). On short-term OM therapy (n=42; 18.8+/-2.4 days; range 5-90 days) a significant (P<0.001) increase in CgA (145+/-22 microg/l) from baseline (63+/-7 microg/l) levels was found. The average net CgA increase on short-term OM therapy was 93+/-20 microg/l. There was a significant correlation between baseline CgA levels and CgA increase on short-term OM therapy (P=0.004) but not between the increase in CgA and the duration of the therapy.
CONCLUSIONS:
An increase in CgA levels quickly follows the start of low dosages of OM. This release is more pronounced when the baseline CgA levels are already increased by slight renal insufficiency or severe hypertension. In this common clinical situation an intensive work-up for NETs is not justified before reassessment of CgA after the withdrawal of OM
Verrucous squamous cell carcinoma of the larynx: Diagnostic and therapeutic considerations
No full textThe clinical findings, histopathology, management and outcome of 31 patients with verrucous squamous cell carcinoma of the larynx (VSCC) are discussed. Laryngeal VSCC is a rare, highly differentiated variant of SCC and has specific morphological features and clinical behavior. A close liaison between the laryngologist and pathologist is needed to formulate a correct diagnosis, because this tumor appears to be malignant clinically and histologically benign. A low-power magnification of multiple large specimens, including the deep margins of the lesion, is required in order to differentiate VSCC from keratosis, verruca vulgaris or SCC with verrucous appearance, and to detect underlying microscopic foci of invasive SCC within or adjacent to a verrucous carcinoma. Long-lasting hoarseness was the most common symptom as the glottic region was the most common site of VSCC. Presumed clinically positive N1 lymph nodes were observed in the necks of 7 patients, but none had metastatic disease on histopathological study. Surgery alone was the most effective form of treatment, as it allowed a good outcome of all treated patients. Surgery plus radiotherapy was associated with an early recurrence and a poor outcome in 2 of 7 patients treated. The generally 'benign' behavior of VSCC allows for conservative surgery, with complete endoscopic resection using the carbon dioxide laser representing a more conservative surgical approach. Neck dissection is not indicated due to the non-metastatic behavior of this tumor
[Adenoid cystic carcinoma of the larynx: review of the literature and caseload].
No full textTwo cases of laryngeal adenoid cystic carcinoma (1 supraglottic, 1 subglottic) are reported, particular attention being paid to diagnosis and treatment. The literature on this topic has been reviewed, in order to describe the natural course and the different treatments of this tumour. The authors underline the difficulty in evaluating the effectiveness of treatment, due to the insufficient follow-up in most published cases
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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