4,531 research outputs found
The Classics of the First Lorenzo de' Medici. For a New Critical Reading of Corinth
No full textopenIl presente lavoro si propone di rileggere una delle prime opere di Lorenzo de’ Medici, "Corinto", attraverso temi letterari che lo caratterizzano, tenendo presente i modelli latini, greci e italiani ai quali l’autore attinge e confrontandone altri, pertinenti ai temi analizzati. Dopo una rapida introduzione sul contesto storico in cui il poemetto si inserisce, esso viene presentato per quanto concerne il contenuto e la storia redazionale, approfondita nell’Appendice, dove si presentano inoltre i testi di riferimento. Segue dunque la nuova lettura critica. La riflessione sul concetto di classico e su Lorenzo quale autore e personaggio del poemetto conclude l’analisi.The present work aims to re-read one of Lorenzo de’ Medici’s first works, "Corinto", through the literary themes which characterize it, keeping in mind the Latin, Greek and Italian models on which the author draws and comparing others, pertinent to the themes analyzed. After a quick introduction to the historical context in which the poem fits, it is presented in terms of content and editorial history, detailed in the Appendix, where the reference texts are also presented. Thus follows the new critical reading. The reflection on the concept of classic and on Lorenzo as author and character of the poem concludes the analysis
Locally Conformally Flat Ancient Ricci Flows
No full textABSTRACT. We show that any locally conformally flat ancient solution to the Ricci flow must be rotationally symmetric. As a by–product, we prove that any locally conformally flat Ricci soliton is a gradient soliton in the shrinking and steady cases as well as in the expanding case, provided the soliton has nonnegative curvature. Key Words: Ricci solitons, Ricci flo
Biotechnological strategies to induce resistance to sharka in p. persica l.
No full textI virus delle piante rappresentano una sfida per l’agricoltura. Fin dalla sua scoperta all’inizio degli anni Novanta, il meccanismo dell’RNA interference (RNAi) è stato utilizzato come strumento per indurre resistenza a virus in molte specie vegetali. In questa tesi, sono stati riassunti gli aspetti più importanti dell’Host-induced gene silencing (HIGS) come possibile strategia di difesa contro i virus in pianta. In particolare, sono stati descritti i costrutti genici basati sull’RNAi, che vengono utilizzati per indurre nella pianta ospite una resistenza stabile contro i virus, attraverso il post-transcriptional gene silencing (PTGS). Recentemente, come strumento alternativo all’integrazione stabile di costrutti genici RNAi nel genoma della cellula vegetale, è stata esplorata una nuova strategia nota come Spray-induced gene silencing (SIGS), che consiste nell’applicazione di piccole molecole di RNA (sRNAs) direttamente sulla pianta.
Nello specifico, la Sharka rappresenta un danno enorme per la produzione di pesche a livello mondiale e il suo agente eziologico, il plum pox virus (PPV), è incluso nella Top 10 dei virus vegetali più catastrofici. Con il fine ultimo di sviluppare strategie per indurre resistenza al PPV in pesco sfruttando l’RNAi, in questa tesi sono stati tentati entrambi gli approcci HIGS e SIGS. In particolare, con lo scopo di esprimere stabilmente in pesco molecole di RNA a doppio filamento (dsRNA) che inducono il meccanismo dell’RNAi contro il PPV (strategia HIGS), questo lavoro si è focalizzato sullo sviluppo di protocolli in vitro di rigenerazione e trasformazione genetica adatti per questa specie. I risultati ottenuti dimostrano che le varie strategie adottate per la rigenerazione di germogli avventizi in P. persica L. sono efficaci. Anche se con efficienze diverse, la rigenerazione via organogenesi è stata ottenuta a partire da tessuti maturi e giovani di vari genotipi di pesco. Diversamente, l’integrazione del transgene/i nel genoma della pianta usando specie diverse di Agrobacterium e il conseguente ottenimento di piante trasformate è estremamente difficile. In tempi recenti, l’applicazione esogena di RNAi-dsRNA in pianta (strategia SIGS) è considerata un approccio di difesa promettente contro i virus per quelle specie (come il pesco) recalcitranti alla trasformazione genetica. Con l’obiettivo di sviluppare prodotti in grado di tenere sotto controllo le infezioni da PPV in pesco, sono stati anche testati dei protocolli per la produzione e applicazione di RNAi-dsRNA. Sebbene l’agroinfiltrazione e il sistema di trasporto delle molecole siano stati semplici, veloci ed economici, l’approccio SIGS presentato qui è ancora ad uno stadio preliminare e dovrà essere esplorato in un prossimo futuro.
In conclusione, in pesco l’approccio HIGS è complicato come metodo di difesa contro i virus a causa della difficoltà nell’ottenere un sistema di trasformazione efficiente. Di conseguenza, lo sviluppo di nuovi prodotti a base di dsRNA per il controllo delle infezioni virali, come la Sharka ad esempio, sembra essere un’alternativa interessante, ma molte fasi (metodi di produzione e trasporto su tutte) devono essere ottimizzate per poter dimostrare la loro efficacia.Since the beginning of agriculture, plant virus diseases have been a strong challenge for farming. Following its discovery at the very beginning of the '90s, the RNA interference (RNAi) mechanism has been widely studied and exploited as an integrative tool to obtain resistance to viruses in several plant species, with high target-sequence specificity. In this thesis, the major aspects of Host-induced gene silencing (HIGS), as one of the possible plant defence methods, using genetic engineering techniques have been reviewed. In particular, the use of RNAi-based gene constructs to introduce stable resistance in host plants against viral diseases, by triggering post-transcriptional gene silencing (PTGS) has been described. Recently, Spray-induced gene silencing (SIGS), consisting of the topical application of small RNA molecules (sRNAs) to plants, has been explored as an alternative tool to the stable integration of RNAi-based gene constructs in plants.
Specifically, Sharka disease represents a major threat to peach production worldwide and its etiological agent, plum pox virus (PPV), is included in the Top 10 catastrophic plant virus list. With the final aim to develop strategies to induce PPV resistance in peach exploiting RNAi mechanism, both HIGS and SIGS approaches have been attempted. In particular, with the aim to stable express RNAi-inducing dsRNA against PPV in peach (HIGS strategy), the work was focused on development of in vitro protocols for the regeneration and genetic transformation suitable for this species. First of all, an overview of research on the regeneration and genetic transformation in Prunus persica L. have been reviewed and novel strategies and procedures aimed at producing transgenic peach lines have been summarized. The results achieved prove that adventitious shoot regeneration seems to be an effective strategy for this species. Even if with different regeneration efficiencies, adventitious shoot regeneration via organogenesis starting from different mature and juvenile tissues of different peach rootstocks and cultivars has been obtained. Differently, the integration of the transgene/s into the plant genome using different species of Agrobacterium and then the recovery of transformed plants is extremely difficult. In recent times, the exogenus application of RNAi-inducing dsRNA to plants (SIGS strategy) is considered a promising tool for virus defence for those plant species with high recalcitrance to genetic transformation systems, as peach. With the aim to develop RNAi-based products to control PPV infection in peach, protocols for the production and the topical application of RNAi-inducing dsRNA were also tested. Although the agroinfiltration and the molecules delivered system used have been simple, fast, and cheap, the SIGS approach presented here is at very preliminary step and alternative strategies in terms of both dsRNA production and delivery must be explored in the next future.
In conclusion, HIGS strategy proves to be complicated as virus defence approach in peach plant due to the difficulty in obtaining an efficient transformation system. Thus, the development on new dsRNA-based products to control virus infections, as Sharka for instance, looks an interesting alternative, but several steps (i.e production and delivery methods) need to be developed in order to demonstrate their efficacy
Riflessioni di un portoghese sopra il memoriale presentado da'PP. Gesuiti alla santità di PP. Clemente XIII, felicemente regnante : esposte in una lettera scritta ad un amico di Roma
No full textAutor tomado de ICCUEl autor del memorial es Lorenzo Ricci, General de los jesuítasPort. con orla tip.Enc. Perg.Sign.: A-H
Leonardo Ricci. Spazi fluidi che inseguono la vita / Fluid spaces looking for life
No full textLo studio di architettura e di pittura di Leonardo Ricci nella sua casa a Monterinaldi, occupato oggi da due giovani architetti
La Grande Villa Adriana. Il progetto della buffer zone
No full textConcorso internazionale su invito e selezione. Accademia Adrianea, Roma, del 2018. Progetto con menzione.
Gruppo di lavoro formato da Fabio Fabbrizzi (coordinatore scientifico e progettuale), Andrea Ricci, Cecilia Maria Roberta Luschi, Lorenzo Burberi, Francesco Bruni, Fabiola Gorgeri, Tessa Matteini (paesaggio), Anna Lambertini (paesaggio), Mario Bevilacqua (consulenza storica), Marcello Barbanera (consulenza archeologica).
Collaboratore: Fabrizio Forte, Guido Giusfredi, Gabriele Rovetini
Bach-flat gradient steady Ricci solitons
No full textIn this paper we prove that any n-dimensional (n ≥ 4) complete Bach-flat gradient steady Ricci soliton with positive Ricci curvature is isometric to the Bryant soliton. We also show that a three-dimensional gradient steady Ricci soliton with divergence-free Bach tensor is either flat or isometric to the Bryant soliton. In particular, these results improve the corresponding classification theorems for complete locally conformally flat gradient steady Ricci solitons
On the global structure of conformal gradient solitons with nonnegative Ricci tensor
No full textIn this paper we prove that any complete n-dimensional conformal gradient soliton with nonnegative Ricci tensor is either isometric to a direct product R x N^(n−1), or globally conformally equivalent to the Euclidean space R^n or to the round sphere S^n. In particular, we show that any complete, noncompact, gradient Yamabe-type soliton with positive Ricci tensor is rotationally symmetric, whenever the potential function is nonconstant
Ripensare il progetto urbano. Il caso di San Lorenzo a Roma
No full textThis book offers an input of reflections and experimentations regarding the urban project theme, relative to its possible interactions and relations with government transformation and local intervention policies, such as that of the San Lorenzo area in Rome. The volume indicates some of the directions of innovative research: the evolution of urban projects as an integrated governance device for urban transformations; the attention to project quality problems; potentiality of public-private partnerships; preventive feasibility evaluation processes
Risk of Essure microinsert abdominal migration: case report and review of literature
No full textGiuseppe Ricci,1,2 Stefano Restaino,2 Giovanni Di Lorenzo,1 Francesco Fanfani,1 Federica Scrimin,1 Francesco P Mangino1 1Institute for Maternal and Child Health, IRCCS “Burlo Garofolo”, Trieste, Italy; 2Department of Medical Sciences, University of Trieste, Trieste, Italy Purpose: To report a case of Essure microinsert abdominal migration and literature review.Methods: A 41-year-old woman was counseled to undergo Essure sterilization. The procedure was hampered by the presence of endometrial cavity adhesions, obscuring left tubal ostium. By using microscissors the adhesions were progressively lysed. Since the procedure had become very painful, the patient required general anesthesia. Once adhesion lysis was completed, the tubal ostium was well visible. Both devices were then easily introduced into the fallopian tubes. At the end of the procedure, five coils were visible on the right side and five coils on the left side, as recommended.Results: The 3-month hysterosalpingogram follow-up suspected abdominal migration of the left device. Laparoscopy confirmed the device displacement in the left lower abdominal quadrant. Both fallopian tubes and the uterus appeared normal. No signs of perforation were detected. The device was embedded into the omentum, but it was easily removed. Bilateral tubal sterilization was performed by bipolar coagulation.Conclusion: There are only 13 cases, including the present, of Essure abdominal migration in the literature. In most cases, abdominal displacement of the microinsert is asymptomatic and does not induce tissue damage. However, in some cases, it may cause a severe adverse event, requiring major surgery. Therefore, removal of the migrated device should be performed as soon as possible. Moreover, during presterilization counseling, the patient should also be correctly informed about the risk of this rare but relevant complication, as well as about the surgical interventions that could be required to solve it. Keywords: abdominal migration, Essure, hysteroscopic sterilization, hysteroscopy, tubal sterilizatio
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