193 research outputs found
An Environment For Knowledge Discovery In Biology
No full textThis paper describes a data mining environment for knowledge discovery in bioinformatics applications. The system has a generic kernel that implements the mining functions to be applied to input primary databases, with a warehouse architecture, of biomedical information. Both supervised and unsupervised classification can be implemented within the kernel and applied to data extracted from the primary database, with the results being suitably stored in a complex object database for knowledge discovery. The kernel also includes a specific high-performance library that allows designing and applying the mining functions in parallel machines. The experimental results obtained by the application of the kernel functions are reported. © 2003 Elsevier Ltd. All rights reserved.345427447Graves, M., Bergeman, E.R., Lawrence, C.B., A graph conceptual model for developing human genome center databases (1996) Comput. Biol. 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Classification of pathology in diabetic eye disease
No full textProliferative diabetic retinopathy is a complication of diabetes that can eventually lead to blindness. Early identification of this complication reduces the risk of blindness by initiating timely treatment. We report the utility of pattern analysis tools linked with a simple linear discriminant analysis that not only identifies new vessel growth in the retinal fundus but also localises the area of pathology. Ten fluorescein images were analysed using seven feature descriptors including area, perimeter, circularity, curvature, entropy, wavelet second moment and the correlation dimension. Our results indicate that traditional features such as area or perimeter measures of neovascularisation associated with proliferative retinopathy were not sensitive enough to detect early proliferative retinopathy (SNR = 0.76, 0.75 respectively). The wavelet second moment provided the best discrimination with a SNR of 1.17. Combining second moment, curvature and global correlation dimension provided a 100% discrimination (SNR = 1)
Development of retinal blood vessel segmentation methodology using wavelet transforms for assessment of diabetic retinopathy
No full textAutomated image processing has the potential to assist in the early detection of diabetes, by detecting changes in blood vessel diameter and patterns in the retina. This paper describes the development of segmentation methodology in the processing of retinal blood vessel images obtained using non-mydriatic colour photography. The methods used include wavelet analysis, supervised classifier probabilities and adaptive threshold procedures, as well as morphology-based techniques. We show highly accurate identification of blood vessels for the purpose of studying changes in the vessel network that can be utilized for detecting blood vessel diameter changes associated with the pathophysiology of diabetes. In conjunction with suitable feature extraction and automated classification methods, our segmentation method could form the basis of a quick and accurate test for diabetic retinopathy, which would have huge benefits in terms of improved access to screening people for risk or presence of diabetes
Informe para la sustentación de expedientes: N° 01104-2012-0-0701-JR-FC-01 / N° 1144-2015/CC1
No full textEl presente informe es el resumen y toma de postura que el autor realiza en referencia a los expedientes N° 01104-2012-0-0701-JR-FC-01 y N°1144-2015/CC1, los mismos que fueron presentados para la obtención de Título de Abogado ante la Universidad Peruana de Ciencias Aplicadas - UPC. Dichos expedientes abordan los temas de separación de cuerpos por causal de separación de hecho y la infracción al deber de idoneidad en el servicio.
Por un lado, el expediente N° 01104-2012-0-0701-JR-FC-01 tiene como tema principal la separación de cuerpos por separación de hecho en el cual se debe de aplicar la ley N°27495, ley que incorpora la separación de hecho como causal de separación de cuerpo y establece la existencia de un cónyuge más perjudicado. Así como, la aplicación del III Pleno Casatorio Civil en el que se establecen los parámetros para el otorgamiento de indemnización al cónyuge más perjudicado.
Por otro lado, el expediente N° 1144-2015/CC1 aborda la infracción al deber de idoneidad en la prestación de servicios de consumidores indirectos expuestos a una relación de consumo. En tal sentido, se analiza los supuestos de hecho para el cumplimento de la existencia de una relación de consumo, así como la de infracción administrativa pasible de sanción por partes de la comisión y sala de protección del consumidor de INDECOPI.
Finalmente, cabe apreciar que en ambas materias legales el derecho tiene una función tuitiva para salvaguardar los derechos e interés de la parte mas vulnerables en dichas relaciones.The present report is the summary and position taken by the author in reference to the files N° 01104-2012-0-0701-JR-FC-01 and N°1144-2015/CC1, which were presented for obtaining a Law Degree before the Peruvian University of Applied Sciences - UPC. These files address the issues of separation of bodies due to de facto separation and breach of the duty of suitability in the service.
On the one hand, file N° 01104-2012-0-0701-JR-FC-01 has as its main subject the separation of bodies due to de facto separation in which Law N° 27495 must be applied, a law that incorporates de facto separation as a cause for separation of bodies and establishes the existence of a more injured spouse. As well as the application of the III Full Casatorio Civil in which the parameters for the awarding of compensation to the most injured spouse are established.
On the other hand, Case No. 1144-2015/CC1 addresses the infringement of the duty of suitability in the provision of services of indirect consumers exposed to a consumer relationship. In this regard, it analyses the factual assumptions for the fulfilment of the existence of a consumer relationship, as well as the administrative infringement punishable by the commission and the consumer protection chamber of INDECOPI.
Finally, it is worth noting that in both legal matters the law has a protective function to safeguard the rights and interests of the most vulnerable parties in such relationships.Trabajo de suficiencia profesiona
O processo de aprendizagem no contexto das organizações participantes do Programa Gaúcho de Qualidade e Produtividade, na região de Santa Maria
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Sócio-Econômico.A realização deste estudo teve como principal objetivo verificar se as empresas de médio e grande porte, participantes do Programa Gaúcho de Qualidade e Produtividade, na região de Santa Maria, orientadas para o aprendizado organizacional, possuem práticas diferenciadas que favoreçam o desenvolvimento do conhecimento. A pesquisa, caracterizada como um estudo multicasos, envolvendo as opiniões e percepções dos dirigentes das organizações, compreendeu uma fase quantitativa e uma fase qualitativa. Na etapa inicial, foram coletados dados referentes a toda a população, visando a identificar as principais organizações orientadas para o aprendizado. Na etapa seguinte, as empresas selecionadas na primeira etapa foram investigadas quanto às práticas adotadas para a gestão do conhecimento, relacionadas ao ambiente, infra-estrutura e conhecimento, e capacidade das pessoas. Com relação às características organizacionais que favorecem a aprendizagem organizacional, os resultados demonstraram que, de modo geral, as organizações encontram-se orientadas para o aprendizado, destacando-se a clareza para definir e comunicar a visão e a capacidade de enfrentar desafios e gerar soluções próprias para atender as suas necessidades. Os dados permitiram concluir, ainda, que, em sua maioria, as organizações possuem ambiente e infra-estrutura favoráveis ao aprendizado, assim como pessoas capazes para o desenvolvimento satisfatório de suas ações. Desse modo, ao ressaltar aspectos importantes, referentes à gestão do conhecimento, os resultados da pesquisa permitiram sugerir outros estudos, visando à obtenção de um maior aprofundamento nessa questão, gerando um processo de aprendizado específico a tal contexto
Ruskin traduzido: Sesame and Lilies por Proust e Catalán
No full textTese (doutorado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão, Programa de Pós-Graduação em Literatura, Florianópolis, 2009.Este trabalho parte da análise das traduções da obra Sesame and Lilies, de John Ruskin, para o francês e para o castelhano para fazer um exame de questões ligadas ao gênero ensaístico, à tradução de ensaios e à autoria. Para isso, analisarei a tradução de Marcel Proust para o francês e seu paratexto e a tradução para o castelhano feita por Miguel Catalán e o respectivo paratexto.This study analises the translations of Sesame and Lilies, by John Ruskin, into French and Spanish in order to examine issues related to the essay as a literary genre, to the translation of essays and to authorship. This exam will be carried out by analising the translation into French by Marcel Proust and its paratext and the translation into Spanish by Miguel Catalán, accompanied by its paratext
A novel polar-based human face recognition computational model
No full textMotivated by a recently proposed biologically inspired face recognition approach, we investigated the relation between human behavior and a computational model based on Fourier-Bessel (FB) spatial patterns. We measured human recognition performance of FB filtered face images using an 8-alternative forced-choice method. Test stimuli were generated by converting the images from the spatial to the FB domain, filtering the resulting coefficients with a band-pass filter, and finally taking the inverse FB transformation of the filtered coefficients. The performance of the computational models was tested using a simulation of the psychophysical experiment. In the FB model, face images were first filtered by simulated V1- type neurons and later analyzed globally for their content of FB components. In general, there was a higher human contrast sensitivity to radially than to angularly filtered images, but both functions peaked at the 11.3-16 frequency interval. The FB-based model presented similar behavior with regard to peak position and relative sensitivity, but had a wider frequency band width and a narrower response range. The response pattern of two alternative models, based on local FB analysis and on raw luminance, strongly diverged from the human behavior patterns. These results suggest that human performance can be constrained by the type of information conveyed by polar patterns, and consequently that humans might use FB-like spatial patterns in face processing
Retinal vessel segmentation using the 2-D Gabor wavelet and supervised classification
No full textAbstract—We present a method for automated segmentation of the vasculature in retinal images. The method produces segmentations by classifying each image pixel as vessel or nonvessel, based on the pixel’s feature vector. Feature vectors are composed of the pixel’s intensity and two-dimensional Gabor wavelet transform responses taken at multiple scales. The Gabor wavelet is capable of tuning to specific frequencies, thus allowing noise filtering and vessel enhancement in a single step. We use a Bayesian classifier with class-conditional probability density functions (likelihoods) described as Gaussian mixtures, yielding a fast classification, while being able to model complex decision surfaces. The probability distributions are estimated based on a training set of labeled pixels obtained from manual segmentations. The method’s performance is evaluated on publicly available DRIVE (Staal et al., 2004) and STARE (Hoover et al., 2000) databases of manually labeled images. On the DRIVE database, it achieves an area under the receiver operating characteristic curve of 0.9614, being slightly superior than that presented by state-of-the-art approaches. We are making our implementation available as open source MATLAB scripts for researchers interested in implementation details, evaluation, or development of methods. Index Terms—Fundus, Gabor, pattern classification, retina, vessel segmentation, wavelet
Redefining the hero archetype: The hero as pragmatist and idealist
No full textThis is a study on the hero using the philosophies of pragmatism and idealism. The author makes use of the hero\u27s journey and some aspects of pragmatism and idealism in redefining the hero archetype. The hero\u27s journey is taken from Joseph Campbell. It is important to note that the words pragmatism and idealism are referred to in their common sense usage for the purpose of the study
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