209 research outputs found
Stances sur l'amour conjugal et mariage du Roi.
Empreinte : e.u. ger. e.s: OnQu 1600 (A)
Signatures : A-C⁴
L'exemplaire à la cote XXII.87.8(R)(Poesie 1) de la bibliothèque Alpha est relié avec "Cent quatrains contenans preceptes & enseignements tres utiles pour la vie de l'homme"
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Emerging evidence indicate that the mammalian checkpoint kinase ATM induces transcriptional silencing in cis to DNA double-strand breaks (DSBs) through a poorly understood mechanism. Here we show that in Saccharomyces cerevisiae a single DSB causes transcriptional inhibition of proximal genes independently of Tel1/ATM and Mec1/ATR. Since the DSB ends undergo nucleolytic degradation (resection) of their 5′-ending strands, we investigated the contribution of resection in this DSB-induced transcriptional inhibition. We discovered that resection-defective mutants fail to stop transcription around a DSB, and the extent of this failure correlates with the severity of the resection defect. Furthermore, Rad9 and generation of γH2A reduce this DSB-induced transcriptional inhibition by counteracting DSB resection. Therefore, the conversion of the DSB ends from double-stranded to single-stranded DNA, which is necessary to initiate DSB repair by homologous recombination, is responsible for loss of transcription around a DSB in S. cerevisiae
Computing in matrix groups without memory
Funding: UK Engineering and Physical Sciences Research Council award EP/K033956/1Memoryless computation is a novel means of computing any function of a set of registers by updating one register at a time while using no memory. We aim to emulate how computations are performed on modern cores, since they typically involve updates of single registers. The computation model of memoryless computation can be fully expressed in terms of transformation semigroups, or in the case of bijective functions, permutation groups. In this paper, we view registers as elements of a finite field and we compute linear permutations without memory. We first determine the maximum complexity of a linear function when only linear instructions are allowed. We also determine which linear functions are hardest to compute when the field in question is the binary field and the number of registers is even. Secondly, we investigate some matrix groups, thus showing that the special linear group is internally computable but not fast. Thirdly, we determine the smallest set of instructions required to generate the special and general linear groups. These results are important for memoryless computation, for they show that linear functions can be computed very fast or that very few instructions are needed to compute any linear function. They thus indicate new advantages of using memoryless computation.Peer reviewe
Computing in permutation groups without memory
Funding: UK Engineering and Physical Sciences Research Council (EP/K033956/1)Memoryless computation is a new technique to compute any function of a set of registers by updating one register at a time while using no memory. Its aim is to emulate how computations are performed in modern cores, since they typically involve updates of single registers. The memoryless computation model can be fully expressed in terms of transformation semigroups, or in the case of bijective functions, permutation groups. In this paper, we consider how efficiently permutations can be computed without memory. We determine the minimum number of basic updates required to compute any permutation, or any even permutation. The small number of required instructions shows that very small instruction sets could be encoded on cores to perform memoryless computation. We then start looking at a possible compromise between the size of the instruction set and the length of the resulting programs. We consider updates only involving a limited number of registers. In particular, we show that binary instructions are not enough to compute all permutations without memory when the alphabet size is even. These results, though expressed as properties of special generating sets of the symmetric or alternating groups, provide guidelines on the implementation of memoryless computation.Peer reviewe
Molecular characterization of Italian and Spanish chestnut trees
Castanea sativa Mill. is the only species of the genus Castanea native to Europe. It is a widespread multipurpose tree cultivated for its nuts and timber. In order to increase the genetic knowledge of chestnut in the Mediterranean area (Italy and Spain), an analysis was carried out on 630 samples (cultivated and wild) using 16 SSRs. Genetic distances and gene pools were calculated using a Bayesian method. A multivariate principal coordinate analysis (PCoA) was performed to validate the revealed genetic structure. The study revealed the existence of two distinct groups of chestnut populations: Spanish and Italian clusters, with a clear separation of the northern and southern Spanish accessions from the Italian ones. The north of Italy and the north-west of Spain emerged as the geographical areas where the genetic variability was preserved, derived from the spontaneous establishment of chestnut. The genetic variation found at cluster level could reflect a combination of historical processes of migration, selection and factors of adaptation to different environments between the Italian and Spanish regions. Furthermore, gene flow between cultivated and wild chestnuts was observed, mainly due to the proximity of cultivated chestnuts to natural populations. Cultivated and wild chestnuts from the Iberian Peninsula and Italy showed no significant differences in terms of genetic variability
Circular Economy and Industrial Symbiosis in a recent analysis of the relevant European projects related to the steel industry|Economia Circolare e Simbiosi Industriale in una recente analisi dei progetti europei rilevanti relativi all'industria siderurgica
Identification of ‘Candidatus Phytoplasma’ species in “huanglongbing” infected citrus orchards in the Caribbean
“Huanglongbing” (HLB) is one of the most devastating diseases of citrus orchards worldwide. Samples from 183 citrus plants of different cultivars and rootstock/cultivar combinations, showing HLB symptoms in three Caribbean countries (Cuba, Jamaica, and Guadeloupe-France), were collected to verify the possible co-infection of ‘Candidatus Phytoplasma’ and ‘Candidatus Liberibacter’ species. The 64% of the samples resulted positive to the ‘Ca. L. asiaticus’ and the 27% to diverse ‘Ca. Phytoplasma’-related species, moreover about the 14% of the samples infected with ‘Ca. Liberibacter’ were also found positive to phytoplasmas, indicating the presence of mixed infection especially in the orchards located in Cuba. Moreover, in one of the samples from Jamaica mixed phytoplasma infection was detected. Moreover the detection of only phytoplasmas in 11 symptomatic citrus samples collected from Cuba and Guadeloupe without ‘Ca. Liberibacter’ detection, confirmed that the symptomatology cannot be the sole criterium to discriminate between the presence of the two pathogens, and molecular detection is necessary to identify single or mixed infections. Diaphorina citri insects collected from Cuba and Guadeloupe resulted infected with ‘Ca. L. asiaticus’ confirming its active role in the dissemination of the pathogen. Only one insect of the Cicadidae family, collected in Guadeloupe, was found positive for phytoplasma presence. Considering that the phytoplasmas belonging to some ‘Candidatus species’ were detected in the three countries in different citrus varieties, a relevant role as phytoplasma reservoir can be attribute to citrus orchards
BAND STRENGTH MEASUREMENT OF THE BAND OF
Author Institution: Jet Propulsion LaboratoryThe band strength of the band of has been determine by measuring the 9 moderately isolated Q-branches, The curves of growth for these Q-branches were calculated using the molecular rotation constants given by Morillon-Chapey and Graner. A. Voigt profile was assumed for the line shape as the measurements were made in the 1.0 to 5.0 Torr pressure range. An approximate method was derived to account for blending of the Q-branches with P branch lines. As is expected, there is no evidence of a vibration rotation interaction effect on the intensities of the Q-branches
Comparative analysis of proteome changes induced by the two spotted spider mite Tetranychus urticae and methyl jasmonate in citrus leaves
Citrus plants are currently facing biotic and abiotic stresses. Therefore, the characterization of molecular traits involved in the response mechanisms to stress could facilitate selection of resistant varieties. Although large cDNA microarray profiling has been generated in citrus tissues, the available protein expression data are scarce, in this study, to identify differentially expressed proteins in Citrus clementina leaves after infestation by the two-spotted spider mite Tetranychus urticae, a proteome comparison was undertaken using two-dimensional gel electrophoresis. The citrus leaf proteome profile was also compared with that of leaves treated over 0-72 h with methyl jasmonate, a compound playing a key role in the defense mechanisms of plants to insect/arthropod attack. Significant variations were observed for 110 protein spots after spider mite infestation and 67 protein spots after MeJA treatments. Of these, 50 proteins were successfully identified by liquid chromatography-mass spectrometry-tandem mass spectrometry. The majority constituted photosynthesis- and metabolism-related proteins. Five were oxidative stress associated enzymes, including phospholipid glutathione peroxidase, a salt stressed associated protein, ascorbate peroxidase and Mn-superoxide dismutase. Seven were defense-related proteins, such as the pathogenesis-related acidic chitinase, the protease inhibitor miraculin-like protein, and a lectin-like protein. This is the first report of differentially regulated proteins after T. urticae attack and exogenous MeJA application in citrus leaves. (C) 2010 Elsevier GmbH. All rights reserved
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