9 research outputs found
Coastal roads atlas. Reshaping daily infrastructures for coastline adaptation
No full textThe widespread poor quality that characterizes many cities and urbanization today is often related to the outdoor spaces. These conditions are common situations in many contexts of our country but are intensified where spatial inequality and environmental vulnerability converge. Although declined in different territories these situations have at their center the complex space of the road. The road system not only contributes significantly to climate change but is also the main victim of the consequences related to these changes. The research investigates the role of the roads and parking spaces, interpreted as the main background of our everyday lives, in facilitating socio-ecological transition of most fragile territories. Particular attention is paid to the different vulnerabilities of Italian coastline and to the ways in which adaptation measures can be implemented to mitigate risks. The initial analyses are focused on developing methods to measure and evaluate the climatic, geophysical, and socio-economic vulnerabilities of coastal roads, which are rendered, through aggregated maps of quantitative and qualitative indicators, in an "Atlas of Coastal Roads". The Atlas is conceived as an operational tool, able to guide stakeholders to develop national and place-specific interpretations
Coastal roads. An Atlas for the socio-ecological transition of coastal territories
No full textThis chapter aims to set out the goals and initial outcomes of an ongoing research project supported by the REACT-EU FSE Program and led by the Department of Architecture and Urban Studies of the Politecnico di Milano in collaboration with Maudlab—PoliMi and Transform Transport. The research focuses on road space as a crucial element for the socio-ecological transition of most fragile territories. By reinterpreting the streets, car parks and other contiguous open spaces as a continuous artefact that characterises the main background of our daily life, it is possible to pay attention to the quality and resilience of much of the territory crossed. This research hypothesis was tested in Italian coastal areas that are most vulnerable to anthropic pressure and climate change phenomena. The fragilities and opportunities were analysed within some significant buffers, including the coastal freeway and urban roads, which are crossed by different geomorphologic and settlement structures. The analyses are aimed at drawing up a trans-scalar Atlas, which relates coastal roads to demographic, socioeconomic and environmental data, describing quantitative and qualitative aspects and showing criticalities and potentials in different national contexts. The Atlas of Coastal Roads is proposed as an operational tool useful for elaborating national-scale and place-specific interpretations; orienting stakeholders, policies and projects towards systemic knowledge and actions; and highlighting new scenarios
Thematic Review on Women’s Perception of Safety While Walking in Public Space: The STEP UP Project
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Thematic Review on Women’s Perception of Safety While Walking in Public Space: The STEP UP Project
by Lily Scarponi
1 [ORCID] , Lamia Abdelfattah
1, Andrea Gorrini
1 [ORCID] , Catalina Valenzuela Cortés
1, Gerardo Carpentieri
2 [ORCID] , Carmen Guida
2 [ORCID] , Floriana Zucaro
2 [ORCID] , Florencia Andreola
3, Azzurra Muzzonigro
3, Laura Da Re
3 [ORCID] , Eleonora Gargiulo
4, Carlos Cañas
4, Jim Walker
4 [ORCID] and Rawad Choubassi
1,*
1
Fondazione Transform Transport ETS, Via Lovanio 8, 20121 Milan, Italy
2
TeMA Lab, Dipartimento di Ingegneria Civile, Edile e Ambientale, Università degli Studi di Napoli Federico II, Piazzale Tecchio, 80, 80125 Naples, Italy
3
Sex and the City APS, Via della Moscova 58, 20121 Milan, Italy
4
Walk21 Foundation, 24 Moorend Road, Cheltenham, Gloucestershire GL530HD, UK
*
Author to whom correspondence should be addressed.
Sustainability 2023, 15(21), 15636; https://doi.org/10.3390/su152115636
Submission received: 13 September 2023 / Revised: 16 October 2023 / Accepted: 30 October 2023 / Published: 5 November 2023
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Abstract
The contributions of this paper are the result of a thematic review conducted on some of the most relevant scientific contributions and policy guidelines about women’s perception of safety while walking in public spaces. The first part of the review focused on 23 scientific references revolving around the keywords “gender”, “safety” and “walkability”. This led to the establishment of three main Safety Factors: (i) Spatial Features (space characteristics/morphological features); (ii) City Use (traces of behavior and presence of city users); and (iii) Hotspots (safe havens and no-go areas); further resulting in 19 sub-factors. The second part of the review covered a collection of 20 reports and 10 guidelines focused on diverse geographical scales, areas of interest and target audiences, as well as data collection methods. This involved the selection of multiple case studies, which are also presented, thus maintaining a geographically diverse sample. As part of the scientific research project “STEP UP—Walkability for Women in Milan”, the outputs of the proposed thematic review will be exploited to help identify challenging areas of Milan (Italy), as samples of analysis to develop a set of policy recommendations to enhance the level of walkability for women
related metabolic cutis laxa
No full textSeveral inborn errors of metabolism show cutis laxa as a highly recognizable feature. One group of these metabolic cutis laxa conditions is autosomal recessive cutis laxa type 2 caused by defects in v-ATPase components or the mitochondrial proline cycle. Besides cutis laxa, muscular hypotonia and cardiac abnormalities are hallmarks of autosomal recessive cutis laxa type 2D (ARCL2D) due to pathogenic variants in ATP6V1A encoding subunit A of the v-ATPase. Here, we report on three affected individuals from two families with ARCL2D in whom we performed whole exome and Sanger sequencing. We performed functional studies in fibroblasts from one individual, summarized all known probands' clinical, molecular, and biochemical features and compared them, also to other metabolic forms of cutis laxa. We identified novel missense and the first nonsense variant strongly affecting ATP6V1A expression. All six ARCL2D affected individuals show equally severe cutis laxa and dysmorphism at birth. While for one no information was available, two died in infancy and three are now adolescents with mild or absent intellectual disability. Muscular weakness, ptosis, contractures, and elevated muscle enzymes indicated a persistent myopathy. In cellular studies, a fragmented Golgi compartment, a delayed Brefeldin A-induced retrograde transport and glycosylation abnormalities were present in fibroblasts from two individuals. This is the second and confirmatory report on pathogenic variants in ATP6V1A as the cause of this extremely rare condition and the first to describe a nonsense allele. Our data highlight the tremendous clinical variability of ATP6V1A related phenotypes even within the same family
Biallelic variants in KYNU cause a multisystemic syndrome with hand hyperphalangism
No full textCatel-Manzke syndrome is characterized by the combination of Pierre Robin sequence and radial deviation, shortening as well as clinodactyly of the index fingers, due to an accessory ossification center. Mutations in TGDS have been identified as one cause of Catel-Manzke syndrome, but cannot be found as causative in every patient with the clinical diagnosis. We performed a chromosome microarray and/or exome sequencing in three patients with hand hyperphalangism, heart defect, short stature, and mild to severe developmental delay, all of whom were initially given a clinical diagnosis of Catel-Manzke syndrome. In one patient, we detected a large deletion of exons 1-8 and the missense variant c.1282C > T (p.Arg428Trp) in KYNU (NM_003937.2), whereas homozygous missense variants in KYNU were found in the other two patients (c.989G > A (p.Arg330Gln) and c.326G > C (p.Trp109Ser)). Plasma and urine metabolomic analysis of two patients indicated a block along the tryptophan catabolic pathway and urine organic acid analysis showed excretion of xanthurenic acid. Biallelic loss-of-function mutations in KYNU were recently described as a cause of NAD deficiency with vertebral, cardiac, renal and limb defects; however, no hand hyperphalangism was described in those patients, and Catel-Manzke syndrome was not discussed as a differential diagnosis. In conclusion, we present unrelated patients identified with biallelic variants in KYNU leading to kynureninase deficiency and xanthurenic aciduria as a very likely cause of their hyperphalangism, heart defect, short stature, and developmental delay. We suggest performance of urine organic acid analysis in patients with suspected Catel-Manzke syndrome, particularly in those with cardiac or vertebral defects or without mutations in TGDS
Located Lexicon: a project that explores how user generated content describes place
No full textThis extended conference paper explores the use and potential of location data in social media contexts. The research involved a series of experiments undertaken to assess the extent to which location information is present in exchanges, directly or indirectly. A prototype application was designed to exploit the insight obtained from the data-gathering experiments. This enabled us to develop a method and toolkit for searching, extracting and visualising mass-generated data for open source use. Ultimately, we were able to generate insights into data quality and ‘scale of query’ for emerging pedagogical research in learning swarms and distributed learners
Efficient intensity-based camera pose estimation in presence of depth
No full textThe widespread success of Kinect enables users to acquire both image and depth information with satisfying accuracy at relatively low cost. We leverage the Kinect output to efficiently and accurately estimate the camera pose in presence of rotation, translation, or both. The applications of our algorithm are vast ranging from camera tracking, to 3D points clouds registration, and video stabilization. The state-of-the-art approach uses point correspondences for estimating the pose. More explicitly, it extracts point features from images, e.g., SURF or SIFT, and builds their descriptors, and matches features from different images to obtain point correspondences. However, while features-based approaches are widely used, they perform poorly in scenes lacking texture due to scarcity of features or in scenes with repetitive structure due to false correspondences. Our algorithm is intensity-based and requires neither point features' extraction, nor descriptors' generation-matching. Due to absence of depth, the intensity-based approach alone cannot handle camera translation. With Kinect capturing both image and depth frames, we extend the intensity-based algorithm to estimate the camera pose in case of both 3D rotation and translation. The results are quite promising. © 2013 SPIE-ISandT.Bay H, 2006, LECT NOTES COMPUT SC, V3951, P404; Ghanem B., 2012, IEEE INT C AC SPEECH; Henry Peter, 2010, RGB D ADV REAS DEPTH; Izadi S., 2011, ACM S US INT SOFTW T; Lowe DG, 2004, INT J COMPUT VISION, V60, P91, DOI 10.1023-B:VISI.0000029664.99615.94; Ma Y., 2003, INVITATION 3 D VISIO; Nestares O., 2010, IEEE INT S MIX AUGM, P257; Nestares O, 2000, MAGNET RESON MED, V43, P705, DOI 10.1002-(SICI)1522-2594(200005)43:5705::AID-MRM133.0.CO;2-R; Zhang T., 2012, IEEE INT C AC SPEECH0
Augmented reality and tourism: a bibliometric analysis of new technological bets in the Post-COVID era
No full textTourism is a sector of high relevance worldwide, due to the multiple impacts it generates in local, regional, national, continental, and global economies, and it is a key generator of employment and provides sustenance to an innumerable number of people around the world. There have been many challenges at a global level to improve the user experience in a particular tourist place, where technology has played a highly relevant role in strengthening the conditions for tourists to achieve immersion in the culture, gastronomy, and recreation. The objective of this literature review is precisely to know and understand the key contributions that are currently being developed around the implementation of augmented reality as tourist technological support for user experiences. The literature on this topic is quite dispersed in specialized databases; therefore, it constitutes an opportunity to carry out a more detailed exploration of the topic. To address the different developments that have been carried out on tourism and augmented reality, an analysis was carried out based on the fusion of scientometric analysis and the metaphor of the Tree of Science, in which two relevant visions about the data were generated. The first focused on the different scientometric statistics regarding countries, authors, universities, or research or technological development centers that currently generate new applications based on augmented reality for tourism. The second focused on an evolutionary analysis based on the Tree of Science, analyzing the origins of the basic contributions of research and how it has evolved over time. This review indicates that the topic is currently valid and that it has been strengthened even more with the post-pandemic process, where many technological developments have been strengthened that allow people to enjoy tourist and cultural sites even without leaving home
A Novel Modeling for Video Summarization Using Constraint Satisfaction Programming
No full textInternational audienceThis paper focuses on automatic video summarization. We propose a novel modeling for summary creation using constraint satisfaction programming (CSP). The proposed modeling aims to provide the summarization method with more flexibility. It allows users to easilymodify the expected summary depending on their preferences or the video type. Using this new modeling, constraints become easier to formulate. Moreover, the CSP solver explores more efficiently the search space. It provides more quickly better solutions. Our model is evaluated and compared with an existing modeling on tennis videos
