187 research outputs found
Repair of Cerebrospinal Fluid Rhinorrhea in a Patient Presenting Empty Sella Syndrome: Case Report and Review of Literature
No full textIntroduction: The cause of Empty Sella syndrome is unknown, however it occurs when intracranial contents herniate through the sellar diaphragm, filling the sella turcica with cerebrospinal fluid (CSF) and giving the appearance of an absent pituitary gland on radiography.
Case Presentation: Author presents a rare case of a 67 years-old woman who was admitted into our department with a complaint of dripping clear fluid from the left side of her nose. Clinical examination and biological, radiological investigations found a CSF leakage through a minute bony defect in the floor of the sella associated with empty Stella syndrome. Treatment consisted of the reparation of the leak using a fascia lata graft, and the sphenoidal sinus was obliterated with fat.
Conclusion: When evaluating patients with non-traumatic CSF rhinorrhea, the otolaryngologist must consider empty sella syndrome as a diagnostic possibility
Identifying and analyzing extremely productive authors in intensive care medicine: A scientometric analysis
No full textIntroduction: Clinical progress relies heavily on research, however, recent years have seen distortions in this process due to the “publish or perish” model. This model is further amplified by team science, leading to inflated author counts and metrics. Recently the rise of hyperprolific (HA) and almost hyperprolific (AHA) authors has been highlighted in the global literature scenario, but data on intensive care medicine (ICM) is lacking. This study aims to investigate HA and AHA authors in ICM and the impact of COVID-19 pandemic on publication rates. Material and methods: We identified authors publishing in ICM journals indexed by Scopus from 2019 to 2023, retrieving their Scopus IDs, publication details, and gender. HA were defined as authors who published at least 73 articles per year, while AHA as authors who published more than 60. The effect of COVID-19 literature was assessed by excluding COVID-related articles from the dataset. Results: We identified 42860 articles in ICM journals, involving 186150 unique authors with a median of 5 publications per author. Only 248 (0.1 %) were extremely productive, with 131 being hyperprolific (HA). Removing COVID-19 papers significantly reduced HA and AHA counts by up to 40 %. Extremely productive authors were predominantly male (91.5 %) and globally distributed, primarily from Europe, Asia, and the Americas. Conclusions: Hyperprolific authors in ICM represent a very small minority. These authors are typically related to ICM, male, senior researchers with a global distribution, who publish high-quality research through a significant research network
The association between disease activity and NT-proBNP in 238 patients with rheumatoid arthritis: a 10-year longitudinal study
No full textIntroduction
Disease activity in patients with rheumatoid arthritis (RA) is associated with increased cardiovascular morbidity and mortality, of which N-terminal pro-brain natriuretic peptide (NT-proBNP) is a predictor. Our objective was to examine the cross-sectional and longitudinal associations between markers of inflammation, measures of RA disease activity, medication used in the treatment of RA, and NT-proBNP levels (dependent variable).
Methods
Two hundred thirty-eight patients with RA of less than 4 years in duration were followed longitudinally with three comprehensive assessments of clinical and radiographic data over a 10-year period. Serum samples were frozen and later batch-analyzed for NT-proBNP levels and other biomarkers. Bivariate, multivariate, and repeated analyses were performed.
Results
C-reactive protein (CRP) levels at baseline were cross-sectionally associated with NT-proBNP levels after adjustment for age and gender (r
2 adjusted = 0.23; P < 0.05). At the 10-year follow-up, risk factors for cardiovascular disease were recorded. Duration of RA and CRP levels were independently associated with NT-proBNP in the final model that was adjusted for gender, age, and creatinine levels (r
2 adjusted = 0.38; P < 0.001). In the longitudinal analyses, which adjusted for age, gender, and time of follow-up, we found that repeated measures of CRP predicted NT-proBNP levels (P < 0.001).
Conclusion
CRP levels are linearly associated with levels of NT-proBNP in cross-sectional and longitudinal analyses of patients with RA. The independent associations of NT-proBNP levels and markers of disease activity with clinical cardiovascular endpoints need to be further investigated
Correction to: Patients in intensive care unit for COVID-19 pneumonia: the lung ultrasound patterns at admission and discharge. An observational pilot study (The Ultrasound Journal, (2021), 13, 1, (10), 10.1186/s13089-021-00213-x)
No full textFollowing publication of the original article [1], we were notified that the first and last author names have been swapped. The original article has been corrected
Normal Variations of the Sella Turcica on Thin-Section Tomography : Concerning the Sellar Floor and the Sphenoid Sinus
No full textNormal variations of the sella turcica on thin-section tomography were studied in 40 normal clinical cases who had no abnormal lesions in the sella turcica and the sphenoid sinus, and in 50 normal dry skulls. Tomography of the sella turcica was performed with hypocycloidal motion at 2 mm intervals in anteroposterior and lateral projections. The author investigated the shape of the sellar floor and the sphenoid sinus and its septa. In the relationship between the sellar floor and the pneumatization of the sphenoid sinus, the sellar height of the major and extensive sellar type was smaller than the height of the conchal and presellar type of sphenoidal pneumatization. In the relationship between the sellar floor and the sphenoid septum, 34 of 68 cuts which had lateral septum or double septa had an asymmetric sellar floor. Twenty-three of 48 cases on frontal tomograms and 24 of 44 cases on lateral tomograms had a downward V-shaped projection of the sellar floor at the site of the attachment of the septum. The sellar floor was concave in 57.0%, flat in 41.1% and convex in 1.9% on the frontal tomograms. Fourteen of 90 cases had different sellar floor shapes on every tomographic cut of the frontal tomograms and eight of 14 cases had asymmetric sellar floors. Fifty-eight cases had concave sellar floors, of which the maximum measurement was 2.4 mm. Twenty-five cases had lateral depression of the sellar floor, the maximum measurement of which was below 2.5mm in ordinary cases and the maximum degree of the angle of the sellar floor was below 10 degrees in those cases who had the same degree of pneumatization in the sphenoid sinus. The thickness of the lamina dura on the anterior and posterior sellar floor was thinner than that on the inferior sellar floor. Localized expansion of the sellar floor was seen in 29 cases and localized thinning was seen in 22 cases. On the other hand, localized expansion associated with thinning of the sellar floor was seen in only four cases and this finding never exceeded one tomographic cut. Therefore, the presence of pituitary microadenoma might be suspected when localized expansion associated with thinning of the sellar floor is seen more than two tomographic cuts.departmental bulletin pape
ENDOSCOPIC REMOVAL OF HYPOPHYSEAL ADENOMAS: A RETROSPECTIVE STUDY
No full textAuthor Keywords:endoscopic; endonasal approach; hypophyseal adenoma; sella turcicaIn this study was assessed the role that the direct endonasal approach with the operating endoscope plays in assisting operations for pituitary adenomas. During a 5-year period, from October 2004 to December 2010 - 42 patients (24 males and 18 females) with hypophyseal adenoma were treated with endoscopic- surgery. Surgery was performed via endonasal trans-sphenoidal approach. Three patients had complications (nasal hemorragia, anosmia, and rhinoliquorrea) in the follow-up period (mean 3 months). No statistical significance was detected between tumor dimensions and complications. On the basis of our experience, it is our opinion that this technique has a low rate of complications, particularly when adequate surgical instruments are used by surgeons who have familiarity with the endoscopic anatomy of the sphenoid sinus
Oxymoron Analysis on A Third Grade Dropout Will Change Your Life Speech
No full textThis study dealt with the figure of speech on A Third Grade Dropout Will
Change Your Life Speech by Rick Rigsby. The objectives of the research were to
find out the types of Oxymoron used and realized on speech. The source of the
data were taken from the A Third Grade Dropout will Change Your Life Speech
video by Rick Rigsby that is the minister, motivational speaker, author and former
college professor. By using descriptive qualitative method of the data were
analyzed and it was found totally 11 sentences, 3 various types. They were 3
Objective Oxymoron, 6 Subjective Oxymorons, 2 Punning Oxymoron. The reason
for using oxymoron in the speech to make something tragic, ironic and make the
listener more interested to focus on the speech and stay tuned with us until the last
of the speech
Effects of a mindfulness-based and acceptance-based group programme followed by physical activity for patients with fibromyalgia: a randomised controlled trial
No full textIntroduction: Non-pharmacological approaches are recommended as first-line treatment for patients with fibromyalgia. This randomised controlled trial investigated the effects of a multicomponent rehabilitation programme for patients with recently diagnosed fibromyalgia in primary and secondary healthcare.
Methods: Patients with widespread pain ≥3 months were referred to rheumatologists for diagnostic clarification and assessment of study eligibility. Inclusion criteria were age 20–50 years, engaged in work or studies at present or during the past 2 years, and fibromyalgia diagnosed according to the American College of Rheumatology 2010 criteria. All eligible patients participated in a short patient education programme before inclusion and randomisation. The multicomponent programme, a 10-session mindfulness-based and acceptance-based group programme followed by 12 weeks of physical activity counselling was evaluated in comparison with treatment as usual, that is, no treatment or any other treatment of their choice. The primary outcome was the Patient Global Impression of Change (PGIC). Secondary outcomes were self-reported pain, fatigue, sleep quality, psychological distress, physical activity, health-related quality of life and work ability at 12-month follow-up.
Results: In total, 170 patients were randomised, 1:1, intervention:control. Overall, the multicomponent rehabilitation programme was not more effective than treatment as usual; 13% in the intervention group and 8% in the control group reported clinically relevant improvement in PGIC (p=0.28). No statistically significant between-group differences were found in any diseaserelated secondary outcomes. There were significant between-group differences in patient’s tendency to be mindful (p=0.016) and perceived benefits of exercise (p=0.033) in favour of the intervention group.
Conclusions: A multicomponent rehabilitation programme combining patient education with a mindfulness-based and acceptance-based group programme followed by physical activity counselling was not more effective than patient education and treatment as usual for patients with recently diagnosed fibromyalgia at 12-month follow-u
A STUDY OF PSYCHOLOGICAL CONFLICT AS A LESBIAN IN ANNIE ON MY MIND NOVEL BY NANCY GARDEN
No full textIn life, there are so many problems. Problems also happen in novel. We find various kinds of problems in novel which reflect the main characters’ daily life. The problems are sometimes in the form of psychological conflict. this kind of conflict is harder to solve especially for minority people such as lesbian. It is interesting to study about psychological conflict in novel, especially in Nancy Garden novel entitled Annie On My Mind. The novel is about Liza Winthrop as the main character faces her problem as a lesbian. This novel also was banned and burnt because Nancy garden was the first author for young adults to create a lesbian love story. Therefore, the researcher has been interested in studying this problem by formulating three research problems such as: (1) How is psychological background of Liza Winthrop as the main character in Annie On My Mind novel by Nancy Garden? (2) What are psychological conflicts that Liza Winthrop got when she realized that she fall in love with Annie Kenyon in Annie On My Mind novel by Nancy Garden? (3) How Liza Winthrop character in the Annie On My Mind novel by Nancy Garden overcomes her psychological conflict ? The research design which used in this research is descriptive qualitative research since the researcher intends to describe psychological backgorund, psychological conflict, and the way overcome the conflict. The data in this research analyzed into six steps, i.e data collection, data analysis, data reduction, data display, conclusion drawing, and data reportation. The researcher found there are five of Liza’s Winthrop character or psychological background that is formed based on her life environment. Those are introvert, masculin, responsible, idealis, and kind-heart person. Those Liza Winthrop’s psychological background influence Liza in overcome her psychological conflict which there are two of the most of psychological conflict faced by her, they are approach-approach conflict and double approach-avoidance conflict. Finally, the researcher really hopes for the student to learn fiction deeply and enjoyed analyzing literary works. And for the lecturer in English Literature Department, lecturer can give explanation about analyzing another aspect in the literary works in order students will not bored in learning or studying fiction. Last, but not least, for the further researcher, they could take different way in analyzing the literary works
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