462 research outputs found
Comparison of ovarian cycles of Hungarian riverine fish species representing different spawning strategies
No full textInvestigations on the ovarian cycle of fish species that inhabit Hungarian rivers are necessitated by both environmental and economic reasons. The objective of our research was to explore new fundamental knowledge concerning the ovarian cycle of the white bream (Blicca bjoerkna, Linnaeus, 1758), barbel (Barbus barbus, Linnaeus, 1758), orfe (Leuciscus idus, Linnaeus, 1758) and nase (Chondrostoma nasus, Linnaeus, 1758). Histological investigation of ovaries and determination of proportions of oocytes in different stages of development is an appropriate method for the description of spawning characteristics of these species. Our results show that the GSI value for all four investigated species starts to increase at the end of summer and reaches its maximum before spawning. In the barbel and white bream, the presence of oocytes in the stage of cortical alveoli and the heterogeneous size of oocytes in the stage of vitellogenesis in the pre-spawning period indicate that barbel and white bream are multiple spawners. In contrast, in the orfe and nase, the absence of oocytes in the stage of cortical alveoli and the homogeneous size of cells in the stage of vitellogenesis indicate that orfe and nase are single spawners
Infringement action of an unregistered community design – general issues
No full textKinga Wernicka - doktor nauk prawnych, Katedra Prawa Unii Europejskiej Wydziału Prawa i Administracji Uniwersytetu Marii Curie-Skłodowskiej; rzecznik patentowy.This article aims to outline the nature of infringement action based on an
unregistered community design. The author indicates the principles of this kind of
action. The article consists of 4 parts (excluding introduction and final remarks).
In the first part, the author indicates the rights conferred by Community designs
based on art. 19.1 of the Council Regulation (EC) No 6/2002 of 12 December 2001
on Community designs, and endeavours to define the scope of protection of an
unregistered design. The second part concerns the limitation of rights conferred by
an unregistered community design, while the third provides analysis on the issue
of the presumption of validity of unregistered community design based on art. 85.2
(1) of regulation 6/2002, in which the author enumerates the proof that should be
produced by the rights holder. The final part of the article presents some remarks on
the procedural aspects of proceedings relating to infringement of an unregistered
design. All aspects concerning the subject of the article are based on judgements of
the Court of Justice of the European Union and the literature on the topic.Uniwersytet Marii Curie-Skłodowskiej243-25
Association analysis of the dopaminergic receptor 2 gene Tag1B rs1079597 and personality traits among a cohort of professional athletes
Get PDFResearch into sports participation has increasingly pointed to inherent biological mechanisms as influential factors alongside psychosocial and environmental elements. The dopaminergic D2 receptor is a strong candidate gene for physical activity behaviour, given its role in locomotor control and reward mechanisms. Hence,
this study aimed to analyse the association of the DRD2 gene Tag1B rs1079597 polymorphism with personality traits in elite athletes. The study group consisted of 395 volunteers. Of these, 163 were professional athletes (22.56±5.9; M = 114, F = 49), and 232 were controls (22.07±4.3; M = 150, F = 82). The MINI-International
Neuropsychiatric Interview and the NEO Five-Factor Inventory were administered in both groups. Genotyping was performed using the real-time PCR method. Statistical analysis was performed: genotypes and alleles frequencies were compared using the chi-square test and the relations between DRD2 Tag1B rs1079597 variants, professional
athletes and control participants and the NEO Five-Factor Inventory were analysed with the factorial ANOVA.
Statistically significant differences were found in the frequency of DRD2 Tag1B rs1079597 genotypes and alleles in the group of professional athletes group compared to the control group. The GG genotype and G allele were significantly more frequent in the group of professional athletes (G/G 0.79 vs G/G 0.66; A/A 0.04 vs A/A 0.03;
A/G 0.17 vs A/G 0.31, p = 0.0056; G 0.87 vs. G 0.81; A 0.13 vs. A 0.19, p = 0.0281) compared to the control group. The professional athletes’ participants, compared to the controls, obtained significantly higher scores in the assessment of NEO-FFI Extraversion (p = 0.0369) and Conscientiousness (p < 0.0001) scales. Additionally,
there was a statistically significant effect of DRD2 rs1079597 genotype association with being a professional athlete on the Openness scale (F2.3389 = 3.07; p = 0.0475; η2 = 0.015) and on the Conscientiousness scale (F2.3389 = 3.23; p = 0.0406; η2 = 0.016). This study highlights the significant associations between the DRD2
Taq1B polymorphicsite and personality traitsin a group of professional athletes. It also demonstratesthe association of Taq1B polymorphism and professional sportsmanship with personality traits measured by NEO-FFI. The results suggest that genetic factors and professional sportsmanship both shape an athlete’s personality traits
Association study of the Taq1D rs1800498 polymorphism of the DRD2 gene with personality traits in a group of athletes
Get PDFIntroduction: This study investigates an association between the human dopamine receptor 2 gene DRD2 Taq1D rs1800498 polymorphism and personality traits among athletes, exploring the genetic underpinnings of sports performance and psychological characteristics. It aims to understand how genetic factors related to dopamine reception influence athletic predispositions and behaviors. Materials and Methods: An association study was conducted with 391 male participants, comparing 159 sports subjects with 232 non-trained controls. Personality traits were assessed using the NEO Five-Factor Inventory, while the DRD2 Taq1D rs1800498 polymorphism was genotyped through real-time PCR. Results: Significant differences in the DRD2 Taq1D rs1800498 genotype and allele frequencies were found between athletes and controls, with athletes displaying higher scores in extraversion and conscientiousness on the NEO-FFI scales. These findings suggest a genetic influence on certain personality traits relevant to sports performance. Conclusions: The study supports the notion that genetic factors, specifically the DRD2 Taq1D rs1800498 polymorphism, are associated with personality traits that may influence athletic performance. This insight contributes to the field of psychogenetics in sports, offering a deeper understanding of how genetics and personality interact to shape athletic capabilities
Wielkie poruszenie
No full textThe post-war displacement of populations, the origin of which is commonly associated with the Yalta Conference, included around six million people on the Polish side alone (in a soulless approximation), which, at the time, constituted nearly a third of the entire population of the country. These figures speak for themselves: it is one of the largest collective experiences of Polish society after World War II and, as such, it should be ascribed a foundational character. In this book, Kinga Siewior assigns herself the task of verifying whether it is also one of the most significant post-war experiences of Polish society and whether it was/is/could be considered in the light of this foundationality. The author is interested in the issue of how post-war migrations of Polish population to the West were represented in recent decades, and how they are portrayed today, as well as what their place and role in the construction of Polish collective identity was considered to be in the past, and how it is seen nowadays. To word it differently: in this book, the author poses the question of whether Polish society can be regarded as a (post)migrational society
Genealogies of Kinga and Other Saintly Female Rulers in the Middle Ages. A Hagiographic Study
No full textCelem niniejszego artykułu jest określenie celu, jakiemu służyły genealogie w żywotach świętych władczyń. W centrum analizy znajduje się Żywot św. Kingi, córki króla Węgier Beli IV i żony księcia krakowskiego Bolesława Wstydliwego, zmarłej w 1292 r. Autor korzysta także z innych źródeł hagiograficznych pochodzących z całego średniowiecza i z różnych krajów Europy. Genealogie te służyły wykazaniu, że zadatki na świętość bohaterka utworu odziedziczyła po przodkach.The present article seeks to define the purpose of the genealogies included in the lives of saintly female rulers. The analysis centres around the Life of Saint Kinga, who died in 1292; she was the daughter of King Bela IV of Hungary and wife of Prince Bolesław V the Chaste of Cracow. The author also uses other hagiographic sources from the entire period of the Middle Ages and various parts of Europe. These genealogies were to demonstrate that the protagonist of the text inherited her potential to be a saint from her ancestors
Wielkie poruszenie
No full textPowojenne przemieszczenia ludności, których genezę potocznie kojarzy się z konferencją w Jałcie, objęły po samej stronie polskiej – w bezdusznym zaokrągleniu –około sześciu milionów osób, co stanowiło wówczas z grubsza prawie 1/3 ogółu populacji kraju. Liczby owe mówią same za siebie: to jedno z największych zbiorowych doświadczeń społeczeństwa polskiego po II wojnie światowej i jako takiemu należałoby mu przypisywać charakter fundacyjny. Zadaniem, jakie sobie w tej książce stawia Kinga Siewior, jest zaś próba zweryfikowania, czy jest to zarazem jedno z najważniejszych powojennych doświadczeń społeczeństwa polskiego i czy było/jest/mogłoby być rozpatrywane w świetle owej fundacyjności. Interesuje ją to, w jaki sposób przedstawiano powojenne migracje polskiej ludności na zachód na przestrzeni ostatnich kilkudziesięciu lat i jak przedstawia się je dziś oraz jakie miejsce i rolę w konstruowaniu polskiej tożsamości zbiorowej przypisywało się im kiedyś, a jakie przypisuje się obecnie. Ujmując rzecz inaczej: w niniejszej książce autorka pyta, czy polskie społeczeństwo można określić mianem społeczeństwa (post)migracyjnego.The post-war displacement of populations, the origin of which is commonly associated with the Yalta Conference, included around six million people on the Polish side alone (in a soulless approximation), which, at the time, constituted nearly a third of the entire population of the country. These figures speak for themselves: it is one of the largest collective experiences of Polish society after World War II and, as such, it should be ascribed a foundational character. In this book, Kinga Siewior assigns herself the task of verifying whether it is also one of the most significant post-war experiences of Polish society and whether it was/is/could be considered in the light of this foundationality. The author is interested in the issue of how post-war migrations of Polish population to the West were represented in recent decades, and how they are portrayed today, as well as what their place and role in the construction of Polish collective identity was considered to be in the past, and how it is seen nowadays. To word it differently: in this book, the author poses the question of whether Polish society can be regarded as a (post)migrational society
Lodz As a Subject of Regional Radio Documentaries
No full textIn the text, the author describes the specifics of the regional radio documentary, and discusses the themes and characters that appear in documents from PR Lodz. The author proposes a division of themes focused on various regional aspects. The research material includes recorded programming published on the radio station’s website during the early days of the site’s existence
What are the effects of taking 300 pills of sodium valproate? - case report
Get PDFPożarowska Kinga, Brzuszkiewicz Kinga, Rudziński Gracjan, Tchórz Michał. What are the effects of taking 300 pills of sodium valproate? - case report. Journal of Education, Health and Sport. 2022;12(8):603-615. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2022.12.08.063
https://apcz.umk.pl/JEHS/article/view/JEHS.2022.12.08.063
https://zenodo.org/record/7011298
The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343.
Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences).
Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159.
Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu).
© The Authors 2022;
This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike.
(http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.
The authors declare that there is no conflict of interests regarding the publication of this paper.
Received: 05.08.2022. Revised: 07.08.2022. Accepted: 20.08.2022.
What are the effects of taking 300 pills of sodium valproate? - case report
Kinga Pożarowska 1, https://orcid.org/0000-0003-0691-0155, [email protected]
Kinga Brzuszkiewicz 1, https://orcid.org/ 0000-0003-3941-027X, [email protected]
Gracjan Rudziński 1, https://orcid.org/0000-0001-8911-9144, [email protected]
Michał Tchórz 2, https://orcid.org/0000-0002-1308-099X, [email protected]
Students’ Research Group at the Department of Toxicology, Medical University ofLublin
Department of Toxicology, Medical University of Lublin
Adres do korespondencji:
Michał Tchórz
Department of Toxicology, Medical University of Lublin al Kraśnicka 100, 20-718 Lublin,
81-537-40-80
ABSTRACT
INTRODUCTION: Sodium valproate is one of the most important antiepileptic drugs. It can be effective as a preventive treatment for migraine, it has also found use in the maintenance treatment of bipolar disorder and acute mania,it is sometimes used in the treatment of chronic neuropathic pain and fibromyalgia, in the treatment of schizophrenia borderline personality disorder and acquired brain injury, this drug is used off-label. Its overdose can be fatal.
MATERIALS AND METHOD: Patient information was collected from hospital records available in the clinical toxicology department. In addition, we conducted a literature review on sodium valproate treatment, its toxicity, side effects and pharmacokinetics using PubMed.
CASE REPORT: A 57-year-old patient with a history of depressive disorders was admitted to the Clinical Department of Toxicology and Cardiology in Lublin for intentional intoxication with the drug Absenor (sodium valproate). The patient had taken 3 packages of Absenor 500 mg (300 tablets in total) for suicidal purposes. The determined concentration of valproic acid was 841 µg/ml, and the patient's condition was very severe. Despite the treatment administered-multiple attempts at gastric lavage, administration of activated charcoal, performance of hemodialysis procedures, administration of infusion of catecholamines, the patient died on the fifth day of hospitalization.
CONCLUSION: An overdose of sodium valproate can be fatal. Keep this in mind when ordering this drug for patients with a positive history of suicide attempts.
KEY WORDS: drug overdose; sodium valproate; sodium valproate overdose; sodium valproate poisoning; suicid
Self-publishing – zarys najważniejszych problemów
No full textThe aim of the following article is to understand popularity of self-publishing phenomena in Poland. At the very begining author is explaining what is self-publishing, taking as an example three most popular self-publishing portals in Poland (Wydaje.pl, Virtualo and RW2010) and comparing them to the foreign self- -publishing portals. Author is writing about different types of self- -publishing: vanity publishing, subsided publishing, partnership self-publishing, whole self-publishing and self-publishing at the Internet platforms. Next part of the article is entitled discussions about advantages and disadvantages of selfpublishing and reception of this phenomena. Author writes about first self-publishing success (novels by Stephen King) and major, american stars of self -publishing in the effort of seeking polish self publishing success stories. It turnes out, that polish self-publishing market is lacking bestsellers and independent authors. Subsequently changes in publishing circuit are analyzed. Author compares self-publishing to second publishing circuit in Poland (1971–1989). Selfpublishing is described as samizdat without political context, in commercialized version. Theory of long tail (by Chris Anderson) “generation upload” theory (Jeff Gomez), cognitive surplus (Clay Shirky) and economical context of self-publishing (free access to publication) are recalled to understand popularity of independent self-publishing. Next author is analyzing an editor side of self-published e-books trying to compare it with traditional published book. It turned out, that independent authors not always follow editorial standards, but they are trying to follow them. They resign from the editorial freedom in order to use one developed by publishing standards – the aim is being understood by readers. In the last part author is referring to the status of an author in self-publishing, pointing changes (and refer to Roland Barthes, Michael Foucault, Walter Benjamin) – author is becoming the most important part of the communication chain in self-publishing by making decisions and staying in touch with a reader.Celem artykułu jest próba zrozumienia popularności zjawiska self-publishingu w Polsce. Na początku autorka stara się zdefiniować pojęcie, przywołując trzy najpopularniejsze portale self-publishingowe w Polsce oraz porównując je z podobnymi portalami zagranicznymi. Pisze także o różnych rodzajach self-publishingu: vanity publishing, publikacja dotowana, partnership self-publishing, całkowity self-publishing i self-publishing na platformach internetowych. W dalszej części artykułu zostały przywołane dyskusje na temat wad i zalet self-publishingu oraz recepcja zjawiska i omówiono pierwsze sukcesy self-publishingu (powieści Stephena Kinga) i historię self-publishingu w Polsce
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