150 research outputs found
Hippocampal activation for autobiographical memories over the entire lifetime in healthy aged subjects: An fMRI study
No full textInternational audienceWe used functional magnetic resonance imaging to determine the cerebral structures required during the recollection of episodic autobiographical memories according to 5 time periods covering the whole lifespan to test the 2 concurring models of memory consolidation, which propose either a temporary (standard model) or a permanent (multiple-trace model) role of the hippocampus in episodic memory retrieval. The experimental paradigm was specially designed to engage subjects (67.17 +/- 5.22 years old) in the retrieval of episodic autobiographical memories, whatever the time period, from personally relevant cues selected by questioning a family member. Moreover, the nature of the memories was checked at debriefing by means of behavioral measures to control the degree of episodicity. Behavioral data showed that recollected memories were characterized by specificity and details whatever their remoteness. Main neuroimaging data (Statistical Parametric Mapping 99) revealed the activation of a network including the left superior frontal gyri, bilateral precuneus/posterior cingulate and lingual gyri, left angular gyrus, and left hippocampus, although the subtraction analyses detected subtle differences between certain time periods. Small volume correction centered on the hippocampus detected left hippocampal activation for all time periods and additional right hippocampal activation for the intermediate periods. Further confirmation was provided by using a 3-way analysis of variance on blood oxygen level-dependent values, which revealed hippocampal activation whatever the time interval. The present data challenge the standard model of memory consolidation and support the multiple-trace model, instead. The comparison with previous literature stresses the idea that a bilateral involvement of the hippocampus characterizes rich episodic autobiographical memory recollection
Séminaire "Maîtrise de la croissance urbaine : outils, comportement des acteurs et impacts environnementaux" - 13/4/15 - La DéfenSe
No full textLe PUCA a le plaisir de vous inviter à la prochaine rencontre du cycle de séminaire « Approches économiques des dynamiques urbaines » organisé en partenariat avec la Maison des Sciences de l’Homme de l’Université de Bourgogne, qui a pour thème : " MAITRISE DE LA CROISSANCE URBAINE : OUTILS, COMPORTEMENT DES ACTEURS, IMPACTS ENVIRONNEMENTAUX" Il se tiendra le Lundi 13 Avril 2015 de 10h00 à 17h00 à la Tour Pascal B de la Défense - Salle N°28P28 [inscription en ligne] [précisions sur le cont..
Résultats de la reconstruction in-situ dans les infections aortiques natives et prothétiques utilisant des allogreffes artérielles cryopréservées
No full textLes allogreffes artérielles cryopréservées représentent une alternative au matériel prothétique ou autologue dans la reconstruction aortique en cas d'infection native ou prothétique, mais les résultats restent discutables. L'objectif de cette étude est d'évaluer à court et moyen terme le recours aux allogreffes cryopréservées en situation aortique. Tous les patients ayant présenté, entre septembre 2004 et juin 2012, une infection aortique native ou prothétique pour laquelle une implantation in-situ d'une allogreffe artérielle a eu lieu, ont été identifiés à partir d'une base de données locale prospectivement constituée. Les données concernant la population, l'indication opératoire, les événements péri-opératoires, la bactériologie, le protocole de cryopréservation et le suivi ont été analysées. Les greffons ont été prélevés chez un donneur en état de mort encéphalique et congelés à - 150C ou à -80C. 54 patients ont été traités par une reconstruction aortique in-situ utilisant une allogreffe artérielle cryopréservée. L'âge moyen était de 66,2 ans (40-83). L'indication reposait sur une infection native chez 16 patients, prothétique chez 37 patients, dont 7 présentaient une fistule aorto-digestive. 12 reconstructions aortiques (22,2%) ont eu lieu dans un contexte d'urgence. Les germes ont été identifiés sur un échantillon peropératoire chez 66,6% des patients, et formaient un spectre large où prédomine le Staphylococcus Aureus (34,4%). La mortalité post-opératoire précoce était de 27,8%, et le taux de complications significatives précoces de 51,8%. Les complications liées au greffon (thrombose, rupture) sont survenues chez 18,5 % des patients. Pendant le suivi ont été observées 2 rechutes infectieuses, et une occlusion de jambage d'allogreffe. Le taux de ré-intervention précoce était de 35,2%, et global de 38,8%. En analyse multivariée, cinq facteurs indépendants étaient prédictifs de décès post-opératoire : l âge > 65 years (p=0.001), l insuffisance rénale chronique (p=0.001), l infection prothétique (p=0.02), les procédures en urgence (p=0.03), et la coronaropathie (p=0,045)La reconstruction aortique par allogreffe cryopréservée s'accompagne d'un taux de mortalité précoce et de complications liées au greffon non négligeables. Ces résultats restent cependant multifactoriels, comparables aux techniques alternatives, et nécessitent une attention particulière quant au comportement précoce du greffon.PARIS6-Bibl.Pitié-Salpêtrie (751132101) / SudocSudocFranceF
Ruptures traumatiques de l'aorte thoracique (place du traitement endo-vasculaire)
No full textPARIS13-BU Serge Lebovici (930082101) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF
Étude au scanner multibarrettes des dissections aigues de type A opérées (cartographie, planimétrie et angioscopie virtuelle)
No full textLa dissection aortique de type A est une pathologie grave dont le pronostic a été amélioré grâce à l amélioration des techniques chirurgicales depuis 15 ans. Les résultats tardifs sont en partie dépendants de l évolution anévrismale et de la rupture potentielle du reste de l aorte. Dans la littérature, l aspect morphologique des dissections de type A opérées a été peu étudié. Cette étude se propose d effectuer une analyse scannographique très précise à un temps tardif de l ensemble de l aorte et de ses branches des patients opérés d une dissection de type A. Matériels et méthodes :de janvier 1982 à février 2006, 160 patients ont été opérés de dissection aortique de type A dans le service de chirurgie cardiaque de l hôpital Henri Mondor (Pr Loisance, Dr Hillion, Dr Kirsch). Soixante et onze patients (42 %) sont décédés en peri opératoire ou dans le suivi, 13 patients ont été perdus de vue (8%) et 17 patients ont eu une chirurgie aortique distale et n ont pas été inclus dans notre étude (10%). Nous avons effectué une étude scannographique intermédiaire chez 20 des 59 patients restants. Les scanners (64 barrettes, General Electric) ont été effectués dans le service d imagerie médicale (Pr Rahmouni, Dr Kobeiter). Plus de 400 items par scanner ont été analysés sur console Light Speed et regroupés en 3 catégories : cartographie, planimétrie avec analyse des surfaces du vrai et du faux chenal, et angioscopie virtuelle. Résultats La cartographie a permis la séparation des patients en 2 groupes : les patients ayant une dissection de l aorte résiduelle (groupe I, n=12, 60%) et les patients sans dissection résiduelle (groupe II, n=8, 40%). Les dissections artérielles des branches aortiques ont intéressé respectivement dans le groupe I et II le tronc artériel brachio-céphalique dans 33% vs. 12,5% ( ns), les artères viscérales dans 60% vs 0% (p50mm) a été découvert chez n=6, 50% des patients du groupe I vs. n=2, 25% des patients du groupe II (ns).Une dilatation de la crosse (>35mm) a été observée chez 10 patients (83%) du groupe I vs. 6 patients (75%) du groupe II (ns). Dans le groupe I, il y avait 6 thromboses du faux chenal associées dans 3 cas à un anévrisme et dans 3 cas à une aorte disséquée non anévrismale. La planimétrie a montré que dans le groupe I, le rapport moyen de surface du vrai chenal sur la surface du faux chenal au niveau de l aorte thoracique haute a été 0,5 chez les patients ayant une aorte disséquée mais de calibre normal, et compris entre 0,3 et 0,5 chez les patients ayant une aorte dilatée (> 35mm, 55mm) have been discovered in n=6, 50% of patients in the group I versus n=2, 25% of patients of group II (ns). A aortic dilatation have been observed in 10 patients (83%) in group I versus 6 patients (75%) in group II (ns). In the group I, there were 6 thrombosis of the false lumen associated in 3 cases to an anevrysm and in 3 cases to non anevrismal aortic dissection. The planimetry have showed in the group I, than the average rapport of the truth lumen surface on the false lumen surface at the thoracic aorta level has been inferior to 0,3 in anevrism group. The rapport has been superior to 0,5 in patients with aortic dissection but a normal size, and incluted between 0,3 and 0,5 in patients with a dilatated aorta (>35mm, <50mm). The virtual angioscopy has been contributed in 75% of patients ( 7 patients, 67% in group I versus 8 patients 100% in group II). The virtual angioscopy has been contributed to find 5 entry door in the patients of group II.PARIS12-CRETEIL BU Médecine (940282101) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF
Cia. São Jorge de variedades. As bastianas
No full textEste trabalho busca relatar e analisar as relações entre ensino, aprendizagem e expressão da linguagem teatral vivenciadas pelos sujeitos envolvidos no processo de montagem e apresentação do espetáculo As Bastianas, realizada pela Cia. São Jorge de Variedades em convívio com os usuários dos Albergues Municipais Projeto.Oficina.Boracéa e Canindé - Núcleo de Cidadania, durante o período de 2002 a 2004. A partir da documentação fotográfica, vídeográfica e escrita disponível, esta pesquisadora pôde narrar toda trajetória do espetáculo teatral desde as primeiras garatujas sobre o texto de Gero Camilo ainda no Teatro de Arena Eugenio Kusnet, até sua estréia e temporada no Canindé e no Projeto.Boracéa.This work aims at reporting and analyzing the relationships between teaching, learning and expression in theatrical language experienced by individuals involved in the process of creating and presenting the play As Bastianas, which was developed by the theater group Cia. São Jorge de Variedades in two different municipal homeless shelters in São Paulo from 2002 to 2004, in daily acquaintance with its inhabitants. From the available written, photographic and videographic documentation the author relates the trajectory of the play, since the first raw sketches from the text by Gero Camilo, when the group was still based in the famous and tiny Teatro de Arena Eugenio Kusnet, until its premiere and season in both shelters
Robotically Assisted Aorto-Femoral Bypass Grafting Surgery: French Experience and Technique Description
No full textBook and Written culture in french Cities-Arsenal (17th to 19th century) : the Rochefort-sur-Mer example
No full textCe travail propose de réinscrire l’ensemble des publications de son auteur dans le cadre d’une histoire de Rochefort, ville-arsenal de la Marine française, appréhendée sous l’angle de l’histoire des pouvoirs de l’écrit. Le cadre chronologique correspond à celui de l’activité de l’arsenal de Rochefort (1666-1927). Le repérage spécifique de ces pouvoirs donne lieu à des comparaisons avec les autres villes-arsenal. Il passe d’abord par l’analyse des fonctions de l’écrit dans l’administration de l’arsenal maritime et par l’étude de l’activité des libraires et des imprimeurs. Une place importante est également faite aux pratiques d’écriture et de lecture des savants travaillant dans les villes-arsenal, à travers l’exemple du médecin de la Marine Pierre-Adolphe Lesson. Enfin, la question de l’appropriation du livre et de l’écrit colonial est abordée en posant les problèmes historiographiques récents liés à l’étude du livre en contexte colonial.This study aims to register all the publications of its author within the framework of a history of Rochefort, city-arsenal of the French Navy, apprehended under the angle of the history of the powers of writing. The chronological frame corresponds to that of Rochefort arsenal activity (1666-1927). The specific identification of these powers gives rise to comparisons with other cities-arsenal. It begins with an analysis of the functions of writing in the administration of the Dockyard and the study of the activity of booksellers and printers. An important place is also made for the writing and reading practices of scientists working in the cities-arsenal, through the example of the Navy physician Pierre-Adolphe Lesson. Finally, the question of the appropriation of the book and the colonial writing is tackled by posing the recent historiographical problems related to the study of the book in colonial context
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No full textA presente pesquisa investiga uma modalidade de prática estética no campo das artes cênicas, desenvolvida com a participação de artistas e outros interessados. Fundada em uma perspectiva existencial da experiência estética, tal modalidade baseia-se em pressupostos elaborados a partir do estudo de aspectos da obra do autor dinamarquês Søren Kierkegaard (1813-1855) e apresenta uma dupla problemática: a singeleza do desejo de expressar a existência poética e a ambiguidade contida em um tema kierkegaardiano por excelência: a vontade de tornar-se si mesmo. A noção de estética existencial é abordada no plano dessa modalidade de prática que, situada filosoficamente no contexto da obra A Doença para a Morte (1849), no âmbito do chamado \"desespero-desafio\" e da \"existência poética orientada ao religioso\", tateia os limites da linguagem verbal, compreendida como \"espaço de possibilidade\", a fim de facultar uma interlocução sui generis entre pontos específicos da rota de leitura perscrutada e os efeitos estéticos de sua recepção. Assim, paralelamente às questões focalizadas em A Doença para a Morte, a escrita trilha a via da participante em primeira pessoa, procurando se acercar da problematização suscitada pela prática proposta, mediante um itinerário peculiar de leitura de alguns tópicos presentes na produção pseudonímica de Kierkegaard, particularizados em capítulos selecionados das obras: Ou-Ou. Um Fragmento de Vida (1843); Temor e Tremor. Lírica Dialética (1843); A Repetição. Um ensaio em Psicologia Experimental (1843); Estádios no Caminho da Vida. Estudos por pessoas diversas (1845). Por meio dessa rota de leitura buscamos circunscrever, fundamentalmente, as vias e os limites da idealidade estética pela afirmação de duas instâncias existenciais que escapam à linguagem verbal e, portanto, resistem à representação: o erótico imediato e a fé. Com esse escopo, a tese se compõe de três partes: Ato I: apresentação do princípio e dos limites da noção de estética existencial no campo problematizado por nossa prática, a partir da relação entre estética e existência; Ato II: exposição das vias da prática estética em seus pressupostos, com a identificação dos artistas e participantes na pesquisa na qualidade de coautores, e do Livro de Cultivo, método-objeto criado para abrigar as proposições estéticas associadas ao Stemning, título do primeiro capítulo da obra Temor e Tremor, eixo central da nossa prática. Em acréscimo, investigação conceitual acerca da própria noção de stemning (do dinamarquês: \"atmosfera\", \"disposição\", \"afinação\", \"tonalidade afetiva\", \"estado de espírito\", \"ambiência\"), vinculada à instância do erótico imediato; Ato III: reconhecimento do ato de assistir e de ser assistido como finalidade da recordação pelo entendimento de que recordar a obra é assisti-la; exame da idealidade estética da recordação como poder poético. Com isso, articulamos nossa própria recordação da prática realizada por meio daquilo que consideramos o princípio formal da problematização: uma recordação filmada, que consiste no \"processo de produção\" [making of] da coleta ou colheita das resultantes estéticas geradas pelo envolvimento dos participantes, na posição tanto de produtores como de espectadores.The present research looks into a modality of aesthetic practice within the field of performing arts, and it was developed with the participation of artists and other interested parties. This modality, based on assumptions put forth from the study of aspects of the works of the Danish author Søren Kierkegaard (1813-1855), is founded in an existential perspective of the aesthetic experience and it introduces a double problematic: the simplicity of the desire to express poetic existence and the ambiguity in a kierkegaardian theme par excellence: the willingness to become oneself. The notion of existential aesthetics is approached within this modality of practice, which is philosophically situated in the context of the book The Sickness Unto Death (1849) as well as within the scope of the so-called \"defiant despair\" and the \"poet-existence inclined towards the religion\". This modality of practice probes the limits of verbal language, understood as \"space of possibility\", in order to allow for a sui generis dialog between specific spots in the examined reading itinerary and the aesthetic effects of its reception. Thus, alongside the issues focused on The Sickness Unto Death, the text follows the path of the participant in first person and seeks to encompass the problematization raised by the proposed practice, which is assisted by a peculiar reading itinerary of some topics included within the pseudonymous production of Kierkegaard, particularized in selected chapters of the works: Either/Or. A Fragment of Life (1843); Fear and Trembling. Dialectical Lyric (1843); Repetition. A Venture in Experimenting Psychology (1843); Stages on Life\"s way. Studies by Various Persons (1845). Through this reading itinerary, we fundamentally seek to circumscribe the avenues and limits of the aesthetic ideality by showcasing two existential instances that evade verbal language and, therefore, resist representation: the immediate eroticism and the faith. Within this scope, this thesis consists of three parts: Act I: presentation of the principle and limits of the notion of existential aesthetics within the field problematized by our practice, based on the relationship between aesthetics and existence; Act II: exposition of the avenues of the aesthetic practice within its assumptions, with the identification of the artists and participants in the research as coauthors, and of the Book of Cultivation, a method-object that was conceived to contain the aesthetic propositions associated with Stemning, title of the first section of Fear and Trembling and central axis of our practice. In addition, act II brings the conceptual investigation about the notion of stemning itself (Danish for: \"mood\", \"tuning up\", \"attunement\" \"atmosphere\") linked to the instance of the immediate eroticism; Act III: recognition of the act of watching/assisting and being watched/assisted as the goal of the recollection through the understanding that to recollect the work means to watch/assist it; examination of the aesthetic ideality of recollection as poetic power. With this, we articulate our own recollection of the practice performed by that which we consider the formal beginning of the problematization: a filmed recollection consisting in the making-of of the collection or harvest of the resulting aesthetics generated by the involvement of the participants in the position of producers as well as that of spectators
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