1,721,020 research outputs found
Updates in regenerative medicine applied to dental sciences
No full textMesenchymal stem cells (MSCs) are found in high concentrations in several tissues, such as umbilical cord, adipose tissue and dental tissue. Dental stem cells reside in many areas of the oral cavity. Thanks to their abilities, dental stem cells could be used to treat diseases and to understand the basic mechanisms of developmental pathologies. There are currently numerous ongoing clinical trials evaluating a broad spectrum of conditions and situations using different stem cell populations. However, stem cell studies are raising profound ethical questions that weigh on the world of scientific research. Stem cells are always a hot topic in the scientific community. Their use is related also to their banking, as cell manipulation is also often related to medical and ethical issues. Many biomedical studies aim to treat diseases that were previously considered incurable with MSCs. All this has created the need to quickly and safely storage stem cells, usually in a stem cell biobank (SCB). Regenerative medicine is the most important approach for achieving complete tissue regeneration using stem cells isolated from adult tissues, embryonic stem cells, but also through the application of induced pluripotent stem cells (iPSC). iPSCs are non-pluripotent cells that are engineered to acquire the ability to differentiate into all different types of cells. In conclusion, the daily use of stem cells in regenerative procedures is still far from being safe and predictable, especially because of the biomedical component, often requiring experienced biologists and complex technologies for cell manipulation and cell banking.
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Prevalence and clinical characteristics of postictal psychiatric symptoms in partial epilepsy
No full textFunctionalization of scaffolds with NaOH-based solution can improve bone regeneration
No full textFunctionalization of scaffolds with NaOH-based solution can improve bone regeneration
Benign cementoblastoma: a clinical case of conservative surgical treatment of the involved tooth
No full textThe benign cementoblastoma (BC) or ''true'' cementoma is a rare benign neoplasm arising from the odontogenic ectomesenchyme and representing about 1% to 6.2% of all odontogenic tumors. The BC more frequently affects young males in an age range of 20-30 years, occurring in the mandible about 3 times more than in the maxilla, and it is always physically attached to the tooth roots. This tumor is often asymptomatic until it produces pain, expansion or swelling of the jaw segment or compression of the inferior alveolar nerve. Early diagnosis is essential to save the tooth by enucleating the tumor, filling the root canals and apicectomy or curettage of the affected roots. A case of BC embedding the mandibular first right molar and resorbing the vestibular cortical bone, in a 48 year-old male, is reported. The radiographic examination showed a well-defined mixed-density unilocular mass, confluent with both the tooth roots of the mandibular first molar and surrounded by a radiolucent rim. A combined endodontic-surgical treatment was performed with the aim to remove the tumor while saving the tooth. Histological findings, differential diagnosis and surgical treatment of the tumor are discussed and compared with similar cases in the literature
Effetti economici e sociali del sisma sugli allevamenti dell’Alto Maceratese
Full text linkIl contributo analizza la filiera zootecnica dell’Alto Maceratese danneggiata dal sisma del
2016. Rispetto ad alcune difficolta storiche (marginalità territoriale e spopolamento), questa analisi si è concentrata sugli effetti del sisma. In collaborazione con i veterinari della
Regione Marche, è stato somministrato ad un campione di 55 famiglie di allevatori un
questionario semi-strutturato al fine di osservare le caratteristiche socio-economiche degli
allevamenti (prevalentemente a media quota e dediti nella metà dei casi unicamente all’attività zootecnica) e i danni prodotti dal sisma (ad abitazioni, patrimonio zootecnico e
strutture agricole). L’ultima sezione del questionario raccoglie alcune proposte di miglioramento nella fase di ricostruzione. Proprio la rigenerazione dei territori colpiti, infatti,
sembra porre ambizione sfide che riguardano il ripristino delle attività lavorative e il ritorno della popolazione sul territorio
Multidisciplinary approach with bilateral sinus-lift and full-mouth implantology in patients with severe sinusitis
No full textMultidisciplinary approach with bilateral sinus-lift and full-mouth implantology in patients with severe sinusitis
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