103 research outputs found
Thermo-Mechanical Finite Element Simulation and Fatigue Life Assessment of a Copper Mould for Continuous Casting of Steel
No full textAbstractThis work describes the thermo-mechanical analysis of a copper mould for continuous steel casting. During the process, the molten steel passes through a water cooled mould. The inner part of the component is subjected to a huge thermal flux. Consequently large temperature gradients occur across the component, especially in the region near to the meniscus, and cause elastic and plastic strains. The aim of this work is to set up an industrially oriented approach to assess the fatigue life of the copper mould. To achieve the goal, a three-dimensional finite element model is analyzed in dependence of four different material models (linear kinematic hardening, combined, stabilized and accelerated material model). The main question is which material model is more suitable to be used. Material coefficients for all applied material and fatigue life models are estimated from experimental, isothermal low cycle fatigue data. The fatigue life is also assessed depending on different material models. The results obtained with the FEM analysis are examined and compared
Edge Asymmetries in Phonology and Morphology
No full textMany phonological and morphological phenomena affect only the left edge of a constituent, but never the right. We argue that such edge bias is due to a formal limitation on constraints: reference to the right edge is not possible. Cases of apparent right-edge reference are due to other factors that happen to approximate right-edgeness. We discuss edge asymmetries in morphological concatenation (prefixing), footing, larger prosodic inventories at the right edge, apparent right-edge preservation, and opacity.The definitive version of this paper was published in Proceedings of the North East Linguistic Society 30 (NELS 30) and is available at glsa.hypermart.netBye, P., & de Lacy, P. (2000). Edge asymmetries in phonology and morphology,. In J. Kim, & M. Hirotani (Eds.) Proceedings of NELS 30. (pp. 121-135). Amherst, MA:
GLSA Publications.Paul de Lacy's work was supported by the National Science Foundation under grant SBR-9420424
Endophilin-A Deficiency Induces the Foxo3a-Fbxo32 Network in the Brain and Causes Dysregulation of Autophagy and the Ubiquitin-Proteasome System
No full textSummaryEndophilin-A, a well-characterized endocytic adaptor essential for synaptic vesicle recycling, has recently been linked to neurodegeneration. We report here that endophilin-A deficiency results in impaired movement, age-dependent ataxia, and neurodegeneration in mice. Transcriptional analysis of endophilin-A mutant mice, complemented by proteomics, highlighted ataxia- and protein-homeostasis-related genes and revealed upregulation of the E3-ubiquitin ligase FBXO32/atrogin-1 and its transcription factor FOXO3A. FBXO32 overexpression triggers apoptosis in cultured cells and neurons but, remarkably, coexpression of endophilin-A rescues it. FBXO32 interacts with all three endophilin-A proteins. Similarly to endophilin-A, FBXO32 tubulates membranes and localizes on clathrin-coated structures. Additionally, FBXO32 and endophilin-A are necessary for autophagosome formation, and both colocalize transiently with autophagosomes. Our results point to a role for endophilin-A proteins in autophagy and protein degradation, processes that are impaired in their absence, potentially contributing to neurodegeneration and ataxia
TeamWorker: An agent-based support system for mobile task execution
No full textTraditional workflow management systems are considered insufficiently flexible to support autonomous job management via close team working. This paper proposes a multi-agent system approach to enhancing existing workflow management systems to enable team-based job management in the field of telecommunications service provision and maintenance. This paper adopts a component-based approach and explains how applications can be developed by customising the generic components provided by a multi-agent systems framework
Hubungan Curah Hujan dan Hari Hujan Terhadap Produksi Kelapa (Cocos nucifera) Dalam Mapanget (DMT) Pada Beberapa Sistem Jarak Tanam di KP. Mapanget Balit Palma: Hubungan Curah Hujan dan Hari Hujan Terhadap Produksi Kelapa (Cocos nucifera) Dalam Mapanget (DMT) Pada Beberapa Sistem Jarak Tanam di KP. Mapanget Balit Palma
No full textMost of the coconut plantations in Indonesia are dry land, so it is very dependent on rain to meet the water needs of the coconut plants. Changes in rainfall and rainy days affect coconut production. This research was conducted to determine the effect of rainy days and rainfall and its correlation to the production of three varieties of Coconut Tall. The research was conducted at the Mapanget Experimental Garden, IPCRI from January 2019 to April 2019, using data on Coconut Tall Mapanget Inner Coconut production, rainy day data (days) and rainfall (mm) for the period 2014 - 2020 The analytical method used is multiple linear regression and correlation analysis. The results of multiple regression analysis showed that rainy days and rainfall variables had no significant effect at the 5% test level on the increase in the number of bunches/trees/year, the number of fruits/bunch, and the number of fruits/tree/year in the variety Coconut Tall Mapanget. The results of the regression analysis showed that rainfall and rainy days had no significant effect on the coconut production variables, namely the number of bunches/tree/year, number of fruit/bunch, number of fruit/tree/bunch in KP. Mapanget on plants with a spacing of 9 x 9 m, 5 x 16 m, 5 x 3 x 16 m and 5 x 12 m. The various spacing treatments did not have a significant or significant effect on the coconut production component in coconut tall Mapanget (DMT) but in general, the 9 x 9 m spacing was relatively better than the other spacing treatments.
Sebagian besar lahan pertanaman kelapa di Indonesia merupakan lahan kering sehingga sangat bergantung pada hujan untuk memenuhi kebutuhan air tanaman kelapa. Perubahan curah hujan dan hari hujan mempengaruhi produksi kelapa. Penelitian ini dilakukan untuk mengetahui pengaruh hari hujan dan curah hujan serta korelasinya terhadap produksi dari tiga varietas kelapa Dalam. Penelitian dilaksanakan di Kebun Percobaan Mapanget, Balit Palma pada bulan Januari 2019 sampai April 2019, menggunakan data petikan produksi Kelapa Dalam Mapanget (DMT), data hari hujan (hari), dan curah hujan (mm) periode tahun 2014 - 2020. Metode analisis yang digunakan adalah regresi linear berganda dan analisis korelasi. Hasil analisis regresi berganda menunjukkan bahwa variabel hari hujan dan curah hujan tidak berpengaruh nyata pada taraf uji 5% terhadap peningkatan jumlah tandan/pohon/tahun, jumlah buah/tandan, dan jumlah buah/pohon/tahun pada varietas kelapa Dalam Mapanget (DMT). Hasil analisis regresi menunjukkan bahwa curah hujan dan hari hujan tidak berpengaruh signifikan terhadap variabel produksi kelapa yaitu jumlah tandan/pohon/tahun, jumlah buah/tandan, jumlah buah/pohon/tandan di KP. Mapanget pada tanaman dengan jarak tanam 9 x 9 m, 5 x 16 m, 5 x 3 x 16 m dan 5 x 12 m. Pada perlakuan berbagai jarak tanam tidak memberikan pengaruh yang signifikan atau nyata terhadap komponen produksi kelapa dalam Mapanget (DMT) akan tetapi secara umum, jarak tanam 9 x 9 m relatif lebih baik daripada perlakuan jarak tanam lainnya.
 
Relating grass failure on the landside slope to wave overtopping induced excess normal stresses
No full textA high quality safety assessment of levee systems requires a good prediction of when the grass cover of levees fail. Current methods relate the onset of failure to the peak in momentum or energy of the flow, instead of the peak in momentum transfer or energy transfer to the grass cover. The critical velocity necessary in the current methods is thereby difficult to quantify. In line with determining the peak in momentum transfer to the grass, here is shown that the onset of damage of the grass cover can be related to the peak normal stresses acting on the grass cover during wave overtopping. The peak in momentum transfer is thereby assumed to be located at the point of reattachment of the flow with the landside slope. The method is validated against the results of two wave overtopping experiments and benchmarked against the cumulative overload method. An advantage of this method is thereby that both the time and location of the onset of damage can be predicted.Accepted Author ManuscriptHydraulic Structures and Flood Ris
Martin Kasarda’s The history of inferiority as transgression and controversy
Get PDFIn the context of Slovak cultural history, the 1990s marked a transitional period characterized by radical transformations in values – also concerning the role of writers and the evolving social functions of literature. The cultural situation of the era can also be illustrated on the “Kasarda case” of 1991, which followed the magazine publication of the short story “(perhaps) Last supper” by Martin Kasarda (b. 1968). The publication of the text provoked a wave of resentment related to the blasphemous nature of the author’s paraphrase of the canonical biblical story. The article attempts a poetological and literary-historical contextualization of M. Kasarda’s first book, The history of inferiority (1994), where the author elaborated on the aesthetic foundations of the short story that sparked considerable controversy. My interpretation is grounded in the concept of transgression – the moment when a text is shaped by crossing boundaries set by canonized models and codes. The contradictory aesthetic principles employed by the author, reflective of the period, led to the debut’s cautious critical reception
Corporate insurance design with multiple risks and moral hazard
Get PDFThe paper provides novel insights on the effect of a firm’s risk management objective on the optimal design of risk transfer instruments. I analyze the interrelation between the structure of the optimal insurance contract and the firm’s objective to minimize the required equity it has to hold to accommodate losses in the presence of multiple risks and moral hazard. In contrast to the case of risk aversion and moral hazard, the optimal insurance contract involves a joint deductible on aggregate losses in the present setting
FIRST APPLICATION OF InAsSb/InAsSbP AND LEADCHALKOGENIDE INFRARED DIODE LASERS FOR PHOTOACOUSTIC DETECTION IN THE 3.2 AND m REGION.
No full text S Civis et al., Spectrochimica Acta 56, 2125-2130, 2000. A. N. Imenkov et al., Review of Scientific Instruments 72, 1988-1992, 2001.Author Institution: J. Heyrovsk\'{y} Institute of Physical Chemistry, Academy of Sciences of the Czech RepublicA new type of semi-conductor lasers with composition InAsSb/InAsSbP are described. The lasers, working in the range of temperatures (), are tested as a tool of the high resolution absorption spectroscopy of atmospherically important . The spectral charachteristics and tunability of the lasers are probed by means of the vibration-rotation lines of the gaseous molecules and . Experimentaly estimated spectral emission linewidths vary in the range 10 - 30 MHz in dependence on the current passing and laser . Potential applications of the lasers are in the area of analytical chemistry, atmospheric research and kinetics of reactive species. Photoacoustic spectroscopy (PAS) with the InAsSb/InAsSbP and leadchalkogenide tunable infrared diode lasers represents a very promising tool for trace gas monitoring. In this study we present and discuss some results obtained using the and m diode lasers. The results have been obtained with a small and very simple glass photoacoustic cell. The cell consists of a hearing aid microphone (Br\""{u}el \& Kj{\ae}r type 4144/Sennheiser type K6P) and an infrared diode laser. The laser is modulated by means of the amplitude/wavelength modulation at three different resonance frequencies of the cell. The PAS measurements of the dependence of the 2 f signal on the gas mixture pressures yield information on the detection limits and influence of the total pressure in the cell on the amplitude of the photoacoustic signal for different mixtures of the studied gases with air
Examination of the relationship between gaming disorder (GD) and attention deficit hyperactivity disorder (ADHD): a meta-analysis
No full textRationale
The association between childhood and adult Attention Deficit/Hyperactivity Disorder (ADHD) and substance use/substance use disorder (SUD) is well documented (Lee et. al., 2011; Oortmerssen et. al., 2014). There is an increasing number of studies showing an association between non-substance related disorders, such as gambling disorder, compulsive buying and Internet addiction/Internet gaming disorder (Karace et. al., 2017). Despite of the large number of available studies investigating the association between ADHD and gaming disorder, which was included in the 11th revision of the international classification of diseases, as an independent diagnostic category (World Health Organization, 2018), a study collecting and summarizing the different results and estimating the strength of this association is still missing. To fill this gap, we aim to conduct a meta-analysis examining the relationship between Attention Deficit/Hyperactivity Disorder (ADHD) and Gaming Disorder (GD) symptoms.
Lee, S. S., Humphreys, K. L., Flory, K., Liu, R., & Glass, K. (2011). Prospective association of childhood attention-deficit/hyperactivity disorder (ADHD) and substance use and abuse/dependence: a meta-analytic review. Clinical psychology review, 31(3), 328-341.
van Emmerik‐van Oortmerssen, K., van de Glind, G., Koeter, M. W., Allsop, S., Auriacombe, M., Barta, C., ... & Casas, M. (2014). Psychiatric comorbidity in treatment‐seeking substance use disorder patients with and without attention deficit hyperactivity disorder: results of the IASP study. Addiction, 109(2), 262-272.
Karaca, S., Saleh, A., Canan, F., & Potenza, M. N. (2017). Comorbidity between behavioral addictions and attention deficit/hyperactivity disorder: a systematic review. International Journal of Mental Health and Addiction, 15(3), 701-724.
World Health Organization. (2018). International classification of diseases for mortality and morbidity statistics (11th Revision). Retrieved from https://icd.who.int/browse11/l-m/en
Review question
The present meta-analysis will synthesize results regarding the relationship between the presence of attention deficit hyperactivity disorder and gaming disorder symptoms. Additionally, we aim to include analyses examining potential moderating factors affecting the relationship of the two disorders, such as age, gender, country of the sample, date of data collection, study quality.
Anticipated or actual start date
07/06/2020
Anticipated completion date
31/04/2021
Review stage
1. Preliminary searches
Started: Yes
Completed: Yes
2. Piloting of the study selection process
Started: Yes
Completed: Yes
3. Formal screening of search results against eligibility criteria
Started: Yes
Completed: No
4. Data extraction
Started: No
Completed: No
5. Quality assessment
Started: No
Completed: No
6. Basic meta-analysis
Started: No
Completed: No
7. Advanced analysis (publication bias testing, moderator analysis)
Started: No
Completed: No
Named contact
Patrik Koncz
Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence
Patrik Koncz
Named contact email
[email protected]
Organisational affiliation of the meta-analysis
Institute of Psychology, ELTE Eötvös Loránd University
Organisation web address
https://www.ppk.elte.hu/en/
Review team members and their organisational affiliations
Patrik Koncz - Doctoral School of Psychology, ELTE Eötvös Loránd University
Country: Hungary
Dr Orsolya Király - Institute of Psychology, ELTE Eötvös Loránd University
Country: Hungary
Dr Zsolt Demetrovics - Institute of Psychology, ELTE Eötvös Loránd University
Country: Hungary
Dr. Zsofia K. Takacs - Institute of Education, ELTE Eötvös Loránd University
Country: Hungary
Funding sources/sponsors
This study was supported by the Hungarian National Research, Development and Innovation Office [Grant number: KKP126835; ELTE Thematic Excellence Programme 2020, KP2020-IKA-05]. Orsolya Király was supported by the János Bolyai Research Scholarship of the Hungarian Academy of Sciences and by the ÚNKP-20-5 New National Excellence Program of the Ministry for Innovation and Technology from the source of the National Research, Development and Innovation Fund.
The funding institutions had no role in the study design or the data collection, analysis and interpretation of the data, writing the manuscript, or the decision to submit the paper for publication.
Grant number(s)
KKP126835; ELTE Thematic Excellence Programme 2020, KP2020-IKA-05
Conflicts of interest
None
Collaborators
Somogyi Ágnes - Doctoral School of Psychology, ELTE Eötvös Loránd University
Country: Hungary
Search procedure
Databases: PubMed, ScienceDirect, Web of Science, Scopus.
Keywords: ADHD, game, videogame, gaming, addiction, problematic, pathological, dependent, excessive, compulsive, disorder.
Citations of relevant studies are under screening for additional articles.
Eligibility
Studies reporting data related to the association between GD and ADHD.
No restriction on publication date.
Only English language journal articles will be included.
Condition or domain being studied
Attention-deficit hyperactivity disorder is a developmental disorder with two main groups of symptoms: inattentive and hyperactive/impulsive symptoms. Clinicians differentiate between three subtypes of the disorder: predominantly inattentive, predominantly hyperactive/impulsive and combined presentation. For a proper diagnosis, the symptoms have to persist for 6 months, independent from the setting (e.g., at home, school, work, with friends or relatives) to a degree that is inconsistent with the developmental level and they have to negatively affect the social and academic/occupational functioning.
Gaming disorder according to the ICD -11 is characterized by a pattern of persistent or recurrent videogaming behavior which is associated with the following symptoms: impaired control over gaming behavior, increasing priority given to videogaming to the extent that it takes precedence over other life interests and daily activities and the continuation or escalation of videogaming despite the occurrence of negative consequences. The pattern of gaming results in marked distress or functional impairments in different areas of life (social life, education, occupation or other). The ICD-11 differentiates between three subtypes: predominantly online, predominantly offline, and unspecified subtype.
Participants/population
No limitation for age.
General population studies and clinical studies both will be included.
We will include studies examining internet addiction only if those in the sample were playing online games, or the recruitment process is conducted through a videogame or videogame related sites (websites, forums or social media groups relating to videogames or a specific videogame, clubs or organizations related to videogames or a specific videogame etc.).
Intervention(s), exposure(s)
The main purpose of this study is to determine the nature and the size of the association between the two disorders. Studies reporting intervention for ADHD, gaming disorder or both will be scanned, but only data regarding the association between the two disorders before starting the intervention will be included.
Comparator(s)/control
Thereby this study is a meta-analysis examining the relationship between two disorders in non-experimental studies, this question is not applicable.
Types of study to be included
Only quantitative, empirical studies are included.
We will include only primary research or secondary analysis of primary research.
If a result is published more than once, the most up-to-date study or the study with the larger sample size will be included.
No restrictions on the types of study design.
Main outcome(s)
On the one hand, the results of the association between the two disorders may help clinicians diagnosing ADHD patients to take into account the possible risk of developing gaming disorder. On the other hand, diagnosing and treating a potentially underlying ADHD in the treatment of gaming disorder may enhance the treatment outcomes.
Measures of effect
Clinical and non-clinical studies will be analyzed separately
For the analysis, all effect sizes will be transformed into Z-score, and for interpretation, converted back to correlation coefficient (r)
To assess heterogeneity, Q and I2 statistics will be included
Additional outcome(s)
The effect of possible moderator variables (age, gender, country of the sample, date of data collection, study quality)
Data extraction (selection and coding)
Two reviewers will apply the eligibility criteria. They will separately rate the articles for suitability and discuss all emerging disagreements. Coding of relevant data will be done by two reviewers as well and agreement statistics for the assessment of the reliability will be reported.
The following data will be extracted: title, author(s), publication date, journal, country (of the population), study design, sampling method, sample size and gender distribution, age range and mean, sample characteristics (clinical or non-clinical sample), measurement instrument for GD, measurement instrument for ADHD, effect size.
Risk of bias (quality) assessment
Measure(s) for internet addiction/gaming disorder robust to measurement?
Measure(s) for ADHD robust to measurement?
Are the results extracted from the sample representative to the target population?
Was the response rate high enough (>70%) for both ADHD and internet addiction/gaming disorder measures?
Strategy for data synthesis
Outcome measures synthesized: average effect size over the primary studies, variability of effect sizes, confidence intervals, parameter estimates for moderators. The results of publication bias estimation will be included as well.
Specific data to all included studies will be included in table format in the supplement: age, gender, country distribution of the study population, sampling method, sample size and sample type (clinical or non-clinical), measurement tools used.
Analysis of subgroups or subsets
If the studies are heterogenous, we will make moderator analyses to understand the origins of the differences using the following variables:
1. Socio-demographic data: If we find associations between the two disorders, is it true for all ages, genders, dates of data collection and in different cultural contexts?
2. Methodological data: If we find inconsistent data related to the association between the two disorders, can this inconsistency be explained by methodological differences (overall study quality)?
Language
English
Dissemination plans
In addition to the publication in a scientific journal, conference presentations are planned for dissemination
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