134,556 research outputs found
[Acute coronary syndromes with ST-segment elevation: primary angioplasty]. FT Sindrome coronarica acuta con sopraslivellamento del tratto ST: angioplastica
No full textCurvature terms in small time heat kernel expansion for a model class of hypoelliptic Hörmander operators
No full textWe consider the heat equation associated with a class of second order hypoelliptic Hörmander operators with constant second order term and linear drift. We completely describe the small time heat kernel expansions on the diagonal giving a geometric characterization of the coefficients in terms of the divergence of the drift field and the curvature-like invariants of the optimal control problem associated with the diffusion operator
"Gender congruence and acceptance before and after cross-sex hormonal therapy" G. Senofonte, F. Cargnelutti, A. Petrozzi, S. Colangelo, F. Pallotti, D. Paoli, M. Mosconi, F. Lombardo
No full textIntroduction - Gender dysphoria (GD) is a non congruity between an individual’s assigned
gender and the perceived gender identity. This incongruence often produces significant
distress and/or social functioning problems.
Aim – To evaluate gender congruence in FtM and MtF patients using a validated psychometric
scale.
Materials and Methods - We recruited 62 patients (33 FtM and 29 MtF; mean age 27.3 ± 6.7
and 28 ± 6.2 years, respectively) who referred to the outpatient clinic of Endocrinology and
Andrology of the Department of Experimental Medicine for Gender Dysphoria, “Sapienza”
University of Rome, sent by the mental health specialists. Each patient underwent clinical
evaluation, blood hormone testing and completed the Transgender Congruence Scale (TGCS).
This questionnaire is composed of 12 items, exploring Transgender Congruence (TC),
Appearance Congruence (AC) and Gender Identity Acceptance (GIA) (score 1-5). The
evaluation was carried out before the beginning of cross-sex hormone therapy (T0) and after
6 months of therapy (T6).
Results – Baseline evaluation – We detected higher TC scores in FtM patients compared to
MtF (2.65 ± 0.62 vs 2.17 ± 0.73, respectively; p = 0.001), and comparable AC and GIA scores in
both groups (AC: 1.94 ± 0.88 vs 1.69 ± 0.85, p = 0.087; GIA: 4.02 ± 0.26 vs 3.96 ± 0.26, p =
0.409); blood testosterone and estradiol values were within normal cis-gender ranges for all
patients.
FtM post therapy evaluation – At T6 we detected a significant increase of both TC and AC
scores (TC: 2.65 ± 0.62 vs 3.61 ± 0.21, T0 vs T6 respectively, p = 0.001; AC: 1.94 ± 0.88 vs 3.30
± 0.16, T0 vs T6 respectively, p = 0.001). Hormone testing revealed a significant increase of
testosterone levels within eugonadal male range (1.35 ± 0.83 vs 13.36 ± 4.52, T0 vs T6
respectively, p = 0.001).
MtF post therapy evaluation – Similarly, we detected a significant increase of both TC and AC
scores at T6 (TC: 2.17 ± 0.73 vs 3.27 ± 0.57, T0 vs T6, p = 0.005; AC: 1.69 ± 0.85 vs 3.06 ± 0.79,
T0 vs T6, p = 0.011). Blood hormone analysis revealed a significant decrease of testosterone
levels (19.39 ± 10.76 vs 2.70 ± 4.51, T0 vs T6, p = 0.004) without variation of estradiol levels
(24.52 ± 7.61 vs 31.23 ± 14.01, T0 vs T6, p = 0.424). It is noteworthy that TC scores at T6 in
MtF were significantly lower than in FtM (p = 0.048).
Correlations - No significant correlations were detected between sex hormones levels and
TGCS scores in both groups.
Conclusions – Both FtM and MtF individuals show high acceptance of their new gender
identity even before treatment due to their rejection of their birth-assigned gender. Six
months of cross-sex hormone therapy determined an outstanding improvement of selfreported
congruence and appearance scores in both groups, although to a milder extent on
MtF. This reflects the fact that androgen therapy induces marked physical changes in FtM
(menses cessation, hair growth, etc.) and with shorter latency than anti-androgens and
estradiol in MtF. Longer follow-up is required to determine long term maintenance of physical
and psychological effects of therapy
MeSH term explosion and author rank improve expert recommendations
No full textInformation overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank
Implications of Community Policy for the Electric Industries
No full textIn this paper, the authors review the Commission's proposals for introducing competition into the European electricity industry. They caution that such measures risk jeopardizing the real sources of efficiency in the industry, by undermining the mechanisms which permit economies of scale and coordination to be achieved. They do not question that competition can play a role in certain aspects of the industry and identify a number of areas where competition could be developed
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Photoelectrochemical Properties Of Poly(3,4-ethylenedioxythiophene)
No full textThe photoelectrochemical properties of poly(3,4-ethylene dioxythiophene)/ poly(styrene sulfonate) in contact with an electrolytic solution containing a redox couple were studied using the theories for the semiconductor-electrolyte interface. When this polymer-electrolyte interface is illuminated with hv > Eg (gap energy) it exhibits cathodic photocurrent typical of p-type semiconductors, and the flat band potential, density of majority carriers, and the depletion layer thickness can be determined. To complete the band energy diagram of this polymer-electrolyte interface we obtained the band gap energy through the absorption and photocurrent spectra. The relatively low band gap energy (1.5 eV) and the photoeffects observed at the interface suggest its use as the absorbing material in photoelectrochemical cells. © 2000 American Chemical Society.1042661246127Koryta, J., Dvorak, J., Kavan, L., (1993) Principles of Electrochemistry, 2nd Ed., , John Wiley: New YorkBard, A.J., Faulkner, L.R., (1980) Electrochemical Methods - Fundamentals and Applications, , John Wiley: New YorkBantikassegn, W., Inganäs, O., (1995) Thin Solid Films, 293, p. 138Camaioni, N., Casalbore-Miceli, G., Geri, A., Zotti, G., (1998) J. Phys. D: Appl. Phys., 31, p. 1245Gerischer, H., (1990) Electrochim. Acta, 35, p. 1677Miquelino, F.L.C., De Paoli, M.-A., Geniès, E.M., (1994) Synth. Met., 68, p. 91Martini, M., De Paoli, M.-A., (2000) Sol. Energy Mater. Sol. Cells, 60, p. 73Das Neves, S., De Paoli, M.-A., (1998) Synth. Met., 96, p. 48Maia, D.J., Das Neves, S., Alves, O.L., De Paoli, M.-A., (1999) Electrochim. Acta, 44, p. 1945Gazotti, W.A., Faez, R., De Paoli, M.-A., (1996) J. Electroanal. Chem., 415, p. 107Micaroni, L., De Paoli, M.-A., (1996) Sol. Energy Mater. Sol. Cells, 46, p. 79Pei, Q., Zucarello, G., Ahlskog, M., Inganäs, O., (1994) Polymer, 35, p. 1347Dietrich, M., Heinze, J., Heywang, G., Jonas, F., (1994) J. Electroanal. Chem., 369, p. 87De Paoli, M.-A., Casalbore-Miceli, G., Gazotti, W.A., Girotto, E.M., (1999) Electrochim. Acta, 44, p. 2983Micaroni, L., Polo Da Fonseca, C.N., Decker, F., De Paoli, M.-A., (2000) Sol. Energy Mater. Sol. Cells, 60, p. 127Abrantes, L.M., Castillo, L.M., Fleischmann, M., Hill, I.R., Peter, L.M., Mengoli, G., Zotti, G., (1984) J. Electroanal. Chem., 177, p. 129Li, Z., Dong, S., (1992) Electrochim. Acta, 37, p. 1003Glenis, S., Tourillon, G., Garnier, F., (1986) Thin Solid Films, 139, p. 221Butler, M.A., (1977) J. Appl. Phys., 48, p. 1914Finklea, H., (1988) Semiconductors Electrodes, , Elsevier: New YorkSunde, S., Hagen, G., Odegard, R., (1993) J. Electroanal. Chem., 345, p. 59Glenis, S., Tourillon, G., Garnier, F., (1984) Thin Solid Films, 122, p. 9Wilson, R.H., (1977) J. Appl. Phys., 48, p. 4292Skotheim, T., (1981) Appl. Phys. Lett., 38, p. 9Gerischer, H., (1981) Photovoltaic and Photoelectrochemical Solar Energy Conversion, , Cordon, S., Gomes, W. P., Dekeyser, W., Eds.Plenum Press: New YorkWöhrle, D., Meissner, D., (1991) Adv. Mater., 3, p. 12
"Closing the R&D Gap, Evaluating the Sources of R&D Spending"
No full textBoth spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
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