1,992 research outputs found
ALICE status and first results
The ALICE experiment has been recording pp collisions since the start of the Large Hadron Collider in spring 2010. This contribution describes the current status of the detector and the first physics results obtained
Towards harmonisation of case definitions for eight work-related musculoskeletal disorders - an international multi-disciplinary Delphi study
Background: International consensus is needed on case definitions of work-related musculoskeletal disorders and diseases (MSDs) for use in epidemiological research. We aim to: 1) study what information is needed for the case definition of work-related low back pain (LBP), lumbosacral radicular syndrome (LRS), subacromial pain syndrome (SAPS), carpal tunnel syndrome (CTS), lateral and medial elbow tendinopathy, and knee and hip osteoarthritis, and to 2) seek consensus among occupational health professionals/researchers regarding the case definitions of these work-related MSDs. Methods: A two-round Delphi study was conducted with occupational health professionals/researchers from 24 countries. Definition of work-related MSDs were composed of a case definition with work exposures. Round 1 included 32 case definitions and round 2, 60 case definitions. After two rounds, consensus required 75% of the panellists to rate a case definition including work exposures ≥7 points on a 9-point rating scale (completely disagree/completely agree). Results: Fifty-eight panellists completed both rounds (response rate 90%). Forty-five (70%) panellists thought that for LBP a case definition can be based on symptoms only. Consensus was only reached for work-related medial elbow tendinopathy, while the lowest agreement was found for knee osteoarthritis. Where consensus was not reached, this was – except for LBP - related to physical examination and imaging rather than disagreement on key symptoms. Conclusion: Consensus on case definitions was reached only for work-related medial elbow tendinopathy. Epidemiological research would benefit from harmonized case definitions for all MSDs including imaging and physical examination for LRS, SAPS, CTS, lateral elbow tendinopathy and hip and knee osteoarthritis
Study of the p–p–K + and p–p–K - dynamics using the femtoscopy technique
The interactions of kaons (K) and antikaons (K ̄) with few nucleons (N) were studied so far using kaonic atom data and measurements of kaon production and interaction yields in nuclei. Some details of the three-body KNN and K ̄ NN dynamics are still not well understood, mainly due to the overlap with multi-nucleon interactions in nuclei. An alternative method to probe the dynamics of three-body systems with kaons is to study the final state interaction within triplet of particles emitted in pp collisions at the Large Hadron Collider, which are free from effects due to the presence of bound nucleons. This Letter reports the first femtoscopic study of p–p–K + and p–p–K - correlations measured in high-multiplicity pp collisions at s = 13 TeV by the ALICE Collaboration. The analysis shows that the measured p–p–K + and p–p–K - correlation functions can be interpreted in terms of pairwise interactions in the triplets, indicating that the dynamics of such systems is dominated by the two-body interactions without significant contributions from three-body effects or bound states
Study of the p–p–K and p–p–K dynamics using the femtoscopy technique
The interactions of kaons (K) and antikaons (K)
with few nucleons (N) were studied so far using kaonic
atom data and measurements of kaon production and interaction yields in nuclei. Some details of the three-body KNN
and KNN dynamics are still not well understood, mainly
due to the overlap with multi-nucleon interactions in nuclei.
An alternative method to probe the dynamics of three-body
systems with kaons is to study the final state interaction
within triplet of particles emitted in pp collisions at the Large
Hadron Collider, which are free from effects due to the presence of bound nucleons. This Letter reports the first femtoscopic study of p–p–K+ and p–p–K− correlations measured in high-multiplicity pp collisions at √s = 13 TeV
by the ALICE Collaboration. The analysis shows that the
measured p–p–K+ and p–p–K− correlation functions can be
interpreted in terms of pairwise interactions in the triplets,
indicating that the dynamics of such systems is dominated
by the two-body interactions without significant contributions from three-body effects or bound states
Hyperon production in 40 A GeV/c collisions from the NA57 experiment
Enhancements of strange baryon and anti-baryon yields were first observed in Pb–Pb interactions at 160 A GeV/c by WA97. The aim of the NA57 experiment is to investigate how these enhancements behave as a function of energy, and over a broader centrality range than that which was available with WA97. This paper presents a comparison of the hyperon yields in Pb–Pb interactions at 40 A GeV/c and 160 A GeV/c. Preliminary signals for the p-Be data at 40 A GeV/c are also shown
Towards the understanding of the genuine three-body interaction for p-p-p and p-p-Lambda
Three-body nuclear forces play an important role in the structure of nuclei and hypernuclei and are also incorporated in models to describe the dynamics of dense baryonic matter, such as in neutron stars. So far, only indirect measurements anchored to the binding energies of nuclei can be used to constrain the three-nucleon force, and if hyperons are considered, the scarce data on hypernuclei impose only weak constraints on the three-body forces. In this work, we present the first direct measurement of the p–p–p and p–p– Λ systems in terms of three-particle correlation functions carried out for pp collisions at s=13 TeV. Three-particle cumulants are extracted from the correlation functions by applying the Kubo formalism, where the three-particle interaction contribution to these correlations can be isolated after subtracting the known two-body interaction terms. A negative cumulant is found for the p–p–p system, hinting to the presence of a residual three-body effect while for p–p– Λ the cumulant is consistent with zero. This measurement demonstrates the accessibility of three-baryon correlations at the LHC
Derivation and validation of a clinical prediction rule for thrombolysis-associated major bleeding in patients with acute pulmonary embolism: The BACS score
Background: Improved prediction of the risk of major bleeding in patients with acute pulmonary embolism (PE) receiving systemic thrombolysis is crucial to guide the choice of therapy. Methods: The study included consecutive patients with acute PE who received systemic thrombolysis in the RIETE registry. We used multivariable logistic regression analysis to create a risk score to predict 30-day major bleeding episodes. We externally validated the risk score in patients from the COMMAND VTE registry. In addition, we compared the newly created risk score against the Kuijer and RIETE scores. Results: Multivariable logistic regression identified four predictors for major bleeding: recent major bleeding (3 points), age >75 years (1 point), active cancer (1 point) and syncope (1 point) (BACS). Among 1172 patients receiving thrombolytic therapy in RIETE, 446 (38%) were classified as having low risk (none of the variables present, 0 points) of major bleeding according to the BACS score, and the overall 30-day major bleeding rate of this group was 2.9% (95% CI 1.6–4.9%), compared with 44% (95% CI 14–79%) in the high-risk group (>3 points). In the validation cohort, 51% (149 out of 290) of patients were classified as having low risk, and the overall 30-day major bleeding rate of this group was 1.3%. In RIETE, the 30-day major bleeding event rates in the Kuijer and RIETE low-risk strata were 5.3% and 4.4%, respectively. Conclusions: The BACS score is an easily applicable aid for prediction of the risk of major bleeding in the population of PE patients who receive systemic thrombolysis
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