328 research outputs found

    Topology of soft cone metric spaces

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    International Conference on Functional Analysis in Interdisciplinary Applications (FAIA) -- OCT 02-05, 2017 -- Astana, KAZAKHSTANIn Simsek's paper it was introduced a concept of soft cone metric space via soft elements and some fixed point theorems in soft cone metric space were provided. In this work, we examine topological structures such as open ball, soft neighbourhood and soft open set in soft metric spaces and their some properties, and prove that every soft cone metric space under some condition is a soft topological space according to elementary operations on soft sets.Kyrgyz Turkish Manas University [KTMUBAP-2016.FBE.12]This work is supported by Kyrgyz Turkish Manas University in the framework of Scientific Research Projects (KTMUBAP-2016.FBE.12)

    Effects of Topical Phenytoin on Nasal Wound Healing After Mechanical Trauma: An Experimental Study

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    SIMSEK, GOKCE/0000-0001-5281-0986; Ciftci, Osman/0000-0001-5755-3560; kizilay, ahmet/0000-0003-3048-6489Objectives/HypothesisImpaired postoperative wound healing is the second most common morbidity after synechia formation in endoscopic sinus surgery. The aim of this experimental study was to investigate the potential effects of topical phenytoin on wound healing after nasal mucosal trauma in rats. Study DesignAn experimental study at the Inonu University Faculty of Medicine. MethodsTwenty-four rats were randomized into three groups: 1) phenytoin group (n=8), 2) control group (n=8), and 3) vehicle group (n=8). After damaging the right nasal cavity, in the phenytoin group, 1% topical phenytoin cream was applied for 7 days. The rats in the control group did not receive any treatment. The vehicle group was treated with daily topical cold cream for 1 week. The rats were sacrificed at the end, and the nasal cavities were excised. Tissue edema and inflammatory cell infiltration were compared among the groups. Additionally, proliferating cell nuclear antigen (PCNA) and cluster of differentiation 31 (CD31) immunoexpression levels were evaluated. Furthermore, in biochemical analysis, the tissue levels of vascular endothelial growth factor and (EGF) of the groups were investigated. ResultsIn the phenytoin group, tissue edema and inflammatory cell infiltration were significantly decreased, and PCNA and CD31 immunoexpression levels were more prominent (P<.001) and the tissue EGF levels were significantly higher (P<.01). ConclusionsTopical phenytoin treatment may alter the nasal wound healing after mechanical trauma. The potential beneficial effects of topical phenytoin on nasal mucosa should be investigated by further experimental and human trials. Level of EvidenceNA Laryngoscope, 124:E449-E454, 201

    BÜTÜNCÜL BİR MODEL OLARAK AHİLİGİN GİRİSİMCİLİK BOYUTUNUN ZİHNİYET TEMELLERİ

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    nsanlık, tarih boyunca hep mükemmel toplumun pesinde kosmustur. Türk- slam Medeniyeti dengeli fert ve dengeli toplumu saglayarak mükemmele yakın bir toplumun en güzel örnegi olan Ahiligi bundan yüzyıllar önce olusturmustur. Türk insanının öz degerleri olan akıl, ahlak ve çalısmayı tasavvuf egitimi ile harmanlamıs bir ekonomik ve sosyal model olan Ahilik Kurumu insanlıgın refah arayısını temin için sosyal hayatı her yönüyle kucaklamıstır. Ahi Evran'ın insanlık âlemine miras olarak bıraktıgı ve Anadolu'da yasayan bütün insanların gurur kaynagı olan Ahiligin daha iyi anlasılmalı ve yeniden kurum ve kurallarıyla canlandırılıp insanlıga armagan edilmelidir. Burada karsımıza zihniyet kavramı çıkmaktadır. Toplumsal yapıdaki bütün kesimlerin sahip oldugu deger yargıları, tercihler ve egilimlerin hepsini açıklayan zihniyet aslında toplumların hayat tarzını belirleyen düsünce yapısıdır ve bu hayat tarzı ile zihniyet arasındaki iliski de toplumun bilgi hiyerarsisini ve kültür unsurlarını belirler. Ahinin zihniyet yapısının tam olarak anlasılabilmesi, zihniyetin olusmasını saglayan unsurların neler oldugu, içinde yasadıgı toplumun bilgi hiyerarsisi ve kültürünün iyi idrak edilmesi ile saglanabilir. Fakat bu kurumu ve yetistirdigi fert olarak Ahiyi tam anlayabilmemiz için Batı Avrupa pozitivist düsüncesinden sıyrılarak incelemelerde bulunmamız gerekir

    RESEARCH IN USAGE OF FLY ASHES IN THE PRODUCTION OF INTERLOCKING CONCRETE PAVE

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    Uçucu kül (UK), termik santrallerde kömürün yakılması sonucu olusan atık malzemedir. Bu yan ürün betonda puzolanik malzeme olarak kullanılmaktadır. Çimento veya beton üretiminde UK belirli oranlarda kullanılmaya baslamıstır. UK'ler beton üretiminde puzolanik katkı veya dolgu (filler) malzemesi olarak kullanılmaktadır. UK kullanım alanının arttırılması hem ekonomi hem de çevre kirliligi açısından önemlidir. Beton kilitli parke tasları, son zamanlarda oldukça yaygın kullanılmaktadır. Özellikle sehir içi yol ve kaldırımlarda, araç park alanlarında, ticari merkezlerde, fabrika çevreleri ve benzeri yerlerde yogun çalısmalara maruz kalan bölgelerde kullanılmaktadır. Parke tası üretimi, UK kullanımı için genis hacimli bir alandır. UK'ün parke tası üretiminde kullanılması, daha iyi parke tası üretimi, ekonomiklik ve çevre açısından iyi bir yaklasım olacaktır. Çalısmada üç farklı santralden elde edilen uçucu kül %10-20-30-40 oranda çimento yerine ikame edilerek kullanılmıstır. Üretilen parke taslarının yarısı kontrol numunesi olarak kullanılmıstır. Diger yarısı tuzlu küre maruz bırakılmıstır. Kilit taslarının yarmada çekme, su emme ve asınma özellikleri saptanmıstır.Genel olarak %10-20 UK ikameli numuneler, sahit numuneye benzer sonuçlar vermistir. Tuzlu sulama kürü, erken yaslarda, yarmada çekme dayanımını arttırırken, ileriki yaslarda düsürmüstür. Diger fiziksel özelliklerde, tuzlu su kürü etkisi altında, UK kullanılan numuneler daha iyi sonuçlar vermistir.Fly ash is a waste material which is produced in the thermal power plants by burning coal. This side product can be used as pozzolanic material in the concrete.Fly ash has started to be used in concrete production in certain amounts.Fly ashes are used as pozzolanic ingredients or filler materials. Increasing the usage areas of the fly ash is important for both economical and environmental reasons. The usage of the interlocking concrete pave has been increased recently. It is used in the areas in local roads and pavements, parking sites, commercial centers and industrial areas, which are exposed to intensive usage. Production of the concrete pave is a wide area for the consumption of the FA. The usage of the FA in the production concrete pave is a more high quality production, more economical and a more environmentally friendly approach. In this study, fly ash gathered from three different thermal power stations has been used as a substitude to cement in 10-20-30-40 % ratios.Half of the produced paves has been used as control example.The other half has been exposed to salt cure.The splitting tensile strenght and water absorbtion characteristics of the pave have been determined. Generally, the examples with 10-20% substitude, had outcomes similar to the witness example.While the salt cure has improved the tensile strenght in early ages, it has reduced it in older ages.In other physical properties, under exposure to salt cure, the examples with the fly ash had better outcomes

    POLYESTER VE POLİPROPİLEN TELLİ BETONLARIN YOL KAPLAMASI OLARAK KULLANILABİLİRLİGİNİN ARASTIRILMASI

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    Yapılan arastırmalar liflerin beton performansını önemli derecede etkiledigini göstermektedir. Literatürde çelik liflerin betonun egilme dayanımını ve enerji yutma kapasitesini arttırdıgı belirlenmistir. Ancak çelik liflerin beton yol gibi korozif ortamlarda sürekli bulunması zamanla lif etkisinin ortadan kalkmasına neden olabilmektedir. Bu nedenle mikro sentetik lif üreticileri kimyasallara ve korozif ortamlara dayanıklı, aynı zamanda çelik life alternatif olması amacıyla makro sentetik polyester ve polipropilen telleri piyasaya sunmuslardır. Bu çalısmanın amacı, polyester (PYTB) ve polipropilen tel takviyeli betonların (PPTB) çelik tel takviyeli (ÇTB) ve tel takviyesiz betonlara göre taze ve sertlesmis beton deneyleri ile performansları belirlenerek karayolu üst yapısı olarak kullanılabilirliginin arastırılmasıdır. Çalısmada PYTB, PPTB ve ÇTB'lar ile bunlara referans olması için iki farklı tel içermeyen beton tasarımı olmak üzere toplam bes tür beton üretilmistir. Referans betonlarından R1, karısım tasarımı olarak tel içerikli betonlar ile aynıdır. Diger referans beton R2 ise normal yol betonu olarak üretilmistir. Betonlar üzerinde fiziksel deneylerin yanı sıra plak, kiris egilme, yarmada çekme dayanımı, basınç ve elastiklik modülü, yüzey sertligi yardımıyla yaklasık basınç dayanımı, ultrasonik ses geçis hızı, asınma, kapiler su emme ve karbonatlasma derinligi deneyleri yapılmıstır. Çalısmada yapılan plak, kiris egilme ve yarmada çekme deney sonuçlarına göre polipropilen (PP) tellerin betonun ilk çatlak yükünü arttırdıgı, çelik ve polyester (PY) tellerin ise önemli bir etkisinin olmadıgı belirlenmistir. Betonların plak deneylerinden elde edilen enerji yutma degerlerine bakıldıgında PPTB'ların ÇTB'nunun ~%23,5'i ve PYTB'larında ~%14,8'i seviyesinde oldugu görülmüstür. Kiris egilme deney sonuçları da bunu dogrulamaktadır. Asınma deneylerinde asınma kaybı en çok ÇTB'larında görülmüstür Sonuç olarak agır tasıt yükleri ve olumsuz hava kosullarına maruz beton yollar için ÇTB'ların yüksek enerji yutma kapasiteleri sayesinde daha uygun olacagı görülmüstür. Ancak ÇTB'ların ilerleyen yaslarda, özellikle çelik tellerin betonun ilk çatlak yüküne etki etmemesi, asınma nedeni ile betondan daha iri parçalar koparması ve diger korozif sartlar nedeniyle özelligini kaybedebilecegi de dikkate alınmalıdır. Özellikle PP tellerin betonun ilk çatlak yükünü arttırması ve asınma ve korozif sartlardan çok daha az etkilenmesi PPTB'ların ancak ilerleyen yaslarda ÇTB'lara alternatif olabilecegini göstermistir.Researches have been shown that fibres have a significant affect on the concrete performance and also steel fibres increases flexural strength and energy absorbsion. However corrosive environment affects the fibres negatively. Therefore synthetic micro-fibre producers have supplied alternative macrosynthetic polyester and polypropylene fibres to prevent negative effects of corrosion and chemicals. The purpose of this study is to research polyester (PYTB) and polypropylene (PPTB) reinforcement concrete according to steel fiber reinforcement concrete (SFRC) and without fiber concrete which indicated performance by fresh and hardened concrete tests as a concrete pavement. In this study, five species concrete produced that PYTB, PPTB and SFRC fibre concretes and two concretes without fibre to make reference of them. Reference concrete R1 mix design with content is the same as the PYTB, PPTB and SFRC. Other reference R2 mix design is produced normal pavement concrete. On all types of concrete were performed physical experiments, slab tests, beams flexural toughness, tensile split strength, compressive strength and elasticity module, determination of compressive strength of concrete by surface hardness, ultrasonic pulse velocity, abrasion resistance, capillary water absorption and depth of carbonate experiments. According to results of the slab tests, beams flexural toughness and tensile split strength tests PP fibers increased first crack load, steel (S) and polyester (PY) of fibers was not a significant effect. Results of the energy absorbsion have been determined PYTB ~23.5% and PPTB ~14.8% level of SFRC from slab tests verifying by beams flexural toughness test results. The most loss abrasion were seen SFRC. Consequently, SFRC are suited for subjected to heavy vehicle loads and negative air condition concrete pavements owing to high energy absorbsion. But especially steel fibres first crack load on concrete are not a significant effect should be taken into consideration because of the abrasion pull off big particular and other corrosive condition may lose property in later years. It is shown that PP fibres are increased first crack and loss effected abrasion and corrosion, so PPTB should be alternative SFRC in later years

    Marked changes in olfactory perception during early pregnancy: a prospective case-control study

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    SIMSEK, GOKCE/0000-0001-5281-0986Pregnancy seems to be related with a significant change in olfaction. Here, we investigate this theory by testing the odor identification abilities of uncomplicated pregnant women and compare the results with non-pregnant controls. The study included 31 healthy pregnant women in the first trimester (Group 1), 30 in the second trimester (Group 2), 31 in the third trimester, and 30 non-pregnant healthy controls (Group 4). In order to measure odor identification abilities, each subject completed the 12-item Brief Smell Identification Test (BSIT). Next, the demographic characteristics and BSIT scores of the groups were compared. The total BSIT scores of the subjects in Group 1 were found to be significantly lower than those of the other groups (p 0.05). Early pregnancy might be related to significant changes in olfactory performance. The distortion of odor identification in the first trimester might be a causative factor for the development of pregnancy-specific conditions, such as morning sickness and hyperemesis gravidarum, which are both common complaints during the early phase of parturition

    Mean Platelet Volume Decreases in Adult Patients With Obstructive Sleep Apnea After Uvulopalatal Flap Surgery

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    SIMSEK, GOKCE/0000-0001-5281-0986Aim:The main purpose of the study was to investigate changes in mean platelet volume (MPV) values in patients with obstructive sleep apnea syndrome (OSAS) who had undergone uvulopalatal flap (UPF) surgery.Method:The study included a review of the medical records of 37 adult patients who had undergone UPF surgery after being diagnosed with OSAS. The baseline blood parameters of patients, including the MPV and platelet distribution width (PDW) values, were measured and repeated 3 months after treatment. Polysomnographic evaluations of the patients were also performed during admission and the 3rd month control. Comparisons of MPV values and their correlation with polysomnographic parameters were the main outcomes measured.Results:The blood parameters of all patients were similar except for MPV values, which were significantly lower after treatment (P0.05).Conclusion:The UPF surgery, which is a relatively simple surgical intervention to treat OSAS, alleviates nocturnal hypoxic episodes and lowers platelet volume. These may both be important predictors of adverse cardiovascular outcomes related to OSAS

    Epidemia of Tularemia in Central Anatolia

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    Simsek, Hulya/0000-0001-8636-9033; Celebi, Bekir/0000-0002-4545-5573; GAZYAGCI, SERKAL/0000-0002-0043-6942Tularemia is a zoonotic disease caused by Francisella tularensis which can be transmitted to humans by tick bites contaminated water handling infected materials and inhalation. The different clinical types are ulceroglandular, glandular, oropharyngeal, oculoglandular, typhoidal and pneumonic tularemia. Streptomycin and tetracycline are commonly used to treat this infection. In this study approched other patients after the suspected tularemia patient attended to Kirikkale University, Faculty of Medicine with the servical mass complaint at January 2010. To find the reservoir for tularemia, laboratory research was carried on the mice. suspected to be infected with Francisella tularensis in the town of infection
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