2,807 research outputs found

    Investigation of chemical and organoleptic composition of icewines from Eastern Europe

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    Ostapenko, V. Investigation of chemical and organoleptic composition of icewines from Eastern Europe / V. Ostapenko, O. Tkachenko // Наукові здобутки молоді – вирішенню проблем харчування людства у ХХІ столітті: матеріали 84-ї Міжнар. наук. конф. молодих учених, аспірантів і студентів, Київ, 23–24 квіт. 2018 р. / Нац. ун-т харч. технологій. – Київ, 2018. – Ч. 1. – С. 286. – Бібліогр.: 1 назв

    Hormonal profile peculiarities on pancreatic, thyroid and suprarenal hormones in nigeria

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    Approximately 4,5% of Nigerians had diabetes mellitus in 2019 (O.Oguejiofor et al., 2019). Insulin-dependent diabetes mellitus comprises only less than 3% of all the patients, had double increase from 2019th values and showed 21,7% of people (M.Adeyemi Olamoyegun et al., 2024), approximately 3,9 mln in 2019 and will be almost 6 mln by 2045 by forecasting (C.E. Nwator et al., 2024). Mostly Nigerian people between 41 and 60 years get sick (O.O.Adevumi et al., 2022). Elevating in fasting blood glucose and glycosylated Hb more than 6,5% are met rather often in Nigeria whiledefining latent and even non-hidden diabetes mellitus, especially in urban populations (C.N. Okafor et al., 2021). Thyroid diseases take the second position among endocrinopathies worldwide as a whole and in Nigeria particularly with a rate of hyperthyreoidism approximately 60% and hypothyreoidism 40% (E.N.Okafor et al., 2019; B.T.Abera et al., 2021), euthyreoid goiter 53% and subclinical hyperthyreoidism 1-2% (J.O. Edah et al., 2023). Thyroid insufficiency impacts onto carbohydrate metabolism at insulin-independent diabetes mellitus at a greater extent than in people without diabetic mellitus (A.K. Jimoh et al., 2022). Water purifiers can disturb iodine capture by thyroid gland (G.Lisko et al., 2020). Nigerian females get sick on Graves’ disease at a greater extent than males (E.N.Okafor et al., 2019), even with ratio 5:1 on it (A.O. Ogbera et al., 2024) and 20:1 on all thyroid problems (J.O. Edah et al., 2023). Adrenal insufficiency has not only acquired but inheritant character (T.R.P.Mofokeng et al., 2022). Approximately 30-32% of the patients were reported to have low baseline serum cortisol level (I.E.Akase et al., 2019). Cushing’s syndrome was reported to be in adolescent girls (A.E.Edo et al., 2022), adult females (R.Mumini et al., 2024) with female:male ratio 4-5:1 (K.A.A. Abolanle et al., 2020), more seldom morbidity in children. As a whole, it is considered to be met relatively rarely in Nigerian population (R.Mumini et al., 2024)

    Hemoglobinopathies types and their peculiarities in Morocco

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    There are two forms of thalassemia – alpha- and beta-, though clinically thalassemia is divided into minor, intermediate and major. Beta-thalassemia rate is 6-7% in Morocco (S.S. Khandker, 2023) with prevalence in Casablanca 5% among all cities (S. El Kababi, 2019), alpha-thalassemia 0,96%, particularly in the North (A.Laghmich et al., 2019), minor form 1,2% in a whole country. Carriers rate is 6,5% on beta-thalassemia (N.Marzouki, 2022), alpha-thalassemia 0,30% (I.Belmokhtar et al., 2025) and 8% on both thalassemia types (A.Laghmich et al., 2019). Morocco East became thalassemia region after its North and West (I.Belmokhtar et al., 2022). In Rabat, there was a research set which results demonstrated beta-thalassemia major dependence on HLA antigens of both I and II class (S. Ouadghiri et al., 2024). Novel beta-thalassemia variants (C6(-G) and -83(A>G) as well as Hb structural variant D-Ouled Rabah have been discovered first in Morocco. Beta-thalassemia represents the most widely-distributed hemoglobinopathy in Morocco while hemoglobinosis C takes the second position, alpha-thalassemia the third, hemoglobinosis G-Philadelphia - the fourth, D-Ouled Rabah and O-Arab the fifth one (I.Belmokhtar et al., 2025). Morocco has hemoglobinosis C representing mutant Hb with glutaminic acid replacement into lysine in its beta-chain 6 th position. Moroccan people have not only softer heterozygous form with no anemy but also harder homozygous form with moderate hemolytic anemy and Hb crystals in blood smears. Hemoglobinosis C is distributed in Southern Morocco at a greater extent (N.Marzouki, 2022). A combination between these Hb types represents more difficult pathological condition by course than separate hemoglobinoses. There are the data according to which beta-thalassemia can be in a complex with hemoglobinoses C and S with especially hard form of the disease, met in Eastern Morocco mainly (I.Belmokhtar, 2022), except Southern part of the country. Northern Moroccan city Kenitra is distinguished by sickle cell syndromes or hemoglobinosis S in children. Sickle-cell anemy carriers rate is 6,5% and morbidity 80% in the North and 10,5% in other parts of the country (N.Marzouki, 2022)

    Fig. 3 in Eight Species Of Anuran Amphibians (Amphibia, Anura) Found In Ukraine: Comparative Morphology And Classification Of Larval Development Stages

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    Fig. 3. Stages of operculum's development: 6 — operculum touches the belly skin or accretes it, gills can be seen from both sides; 7 — operculum completely covers gills from one (right) side; 8 — external gills are completely covered by operculum.Published as part of Tkachenko, O. V., 2017, Eight Species Of Anuran Amphibians (Amphibia, Anura) Found In Ukraine: Comparative Morphology And Classification Of Larval Development Stages, pp. 343-348 in Vestnik Zoologii 51 (4) on page 345, DOI: 10.1515/vzoo-2017-0039, http://zenodo.org/record/645432

    Fig. 3 in Eight Species Of Anuran Amphibians (Amphibia, Anura) Found In Ukraine: Comparative Morphology And Classification Of Larval Development Stages

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    Fig. 3. Stages of operculum's development: 6 — operculum touches the belly skin or accretes it, gills can be seen from both sides; 7 — operculum completely covers gills from one (right) side; 8 — external gills are completely covered by operculum.Published as part of Tkachenko, O. V., 2017, Eight Species Of Anuran Amphibians (Amphibia, Anura) Found In Ukraine: Comparative Morphology And Classification Of Larval Development Stages, pp. 343-348 in Vestnik Zoologii 51 (4) on page 345, DOI: 10.1515/vzoo-2017-0039, http://zenodo.org/record/645432

    The role of collective motion in examples of coarsening and self-assembly

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    The simplest prescription for building a patterned structure from its constituents is to add particles, one at a time, to an appropriate template. However, self-organizing molecular and colloidal systems in nature can evolve in much more hierarchical ways. Specifically, constituents (or clusters of constituents) may aggregate to form clusters (or clusters of clusters) that serve as building blocks for later stages of assembly. Here we evaluate the character and consequences of such collective motion in a set of prototypical assembly processes. We do so using computer simulations in which a system's capacity for hierarchical dynamics can be controlled systematically. By explicitly allowing or suppressing collective motion, we quantify its effects. We find that coarsening within a two dimensional attractive lattice gas (and an analogous off-lattice model in three dimensions) is naturally dominated by collective motion over a broad range of temperatures and densities. Under such circumstances, cluster mobility inhibits the development of uniform coexisting phases, especially when macroscopic segregation is strongly favored by thermodynamics. By contrast, the assembly of model viral capsids is not frustrated but is instead facilitated by collective moves, which promote the orderly binding of intermediates consisting of several monomers

    Analysis of asthenic phenomens in patients with type 2nd diabetes mellitus in the clinical and psychological aspect

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    Tkachenko O. V. Analysis of asthenic phenomens in patients with type 2nd diabetes mellitus in the clinical and psychological aspect. Journal of Education, Health and Sport. 2017;7(3):736-744. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1000976 http://ojs.ukw.edu.pl/index.php/johs/article/view/4953 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26.01.2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Author (s) 2017; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 27.03.2017. Revised 28.03.2017. Accepted: 29.03.2017. analysis OF ASTHENIC PHENOMENS IN PATIENTS WITH type 2nd DIABETES MELLITUS IN THE CLINICAL AND PSYCHOLOGICAL aspect O. V. Tkachenko Zaporozhiye Medical Academy of Postgraduate Training of the Ukrainian Ministry of Health Care e-mail: [email protected] Abstract Aim – to analyze the peculiarities of asthenic manifestations in patients with type 2nd diabetes mellitus (DM) in clinical and psychological perspective. Materials and methods. We examined in 543 patients with type 2nd DM. The first clinical group (CG-1) was 57 patients with type 2nd DM of mild severity; the average age in the group was (51,80±1,28) years. The second clinical group (CG-2) made up of 312 patients with type 2nd DM, moderate severity; mean age in the group was (55,10±1,12) years. The third clinical group (CG-3) included 174 patients with type 2nd DM, severe degree of severity; the average age in the group was (61.80±0,85) years. Research methods: clinical-anamnestic, clinical-psychopathological, statistical. Results. The marked prevalence of asthenic syndrome in patients wath type 2nd DM 52,30%, which is almost half among all surveyed type 2nd DM. Discovered the direct correlation of asthenic symptoms with the severity of the type 2nd DM (rs = 0.4033, p<0.01). The factors in the risk of asthenic syndrome in patients with type 2nd DM was installed, among them is dominated by a moderate and severe degree of type 2nd DM, combined with obesity 2 degrees, DEP II degree, ischemic heart disease, heart failure, degenerative dystrophic lesions of the spine. Established that there is a direct correlation asthenic syndrome to the severity of type 2nd DM, as well as the accompanying somatic pathology. Established dominance in CG-1 and CG-2 component fatigue "mental fatigue" and CG-3 component "physical fatigue". Conclusions. Features of asthenic manifestations in patients with type 2nd DM in clinical and psychological perspective were investigated. The detection rate of asthenic manifestations among patients with type 2nd DM and the factors for their amplification were established. The organic etiology of asthenic manifestations have been proven; presentation about the stages of development of asthenic symptoms in patients with type 2nd DM were improved. Key words: type 2nd diabetes, asthenic syndrome, mental pathology, psychodiagnosi

    Этиопатогенетические, психопатогенетические и клинические аспекты когнитивных нарушений при сахарном диабете 2-го типа = Etiopathogenic, psychopathogenetic and clinical aspects of cognitive disorders in type 2 diabetes

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    Tkachenko О. V. Этиопатогенетические, психопатогенетические и клинические аспекты когнитивных нарушений при сахарном диабете 2-го типа = Etiopathogenic, psychopathogenetic and clinical aspects of cognitive disorders in type 2 diabetes. Journal of Education, Health and Sport. 2015;5(11):279-288. ISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.34006 http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%2811%29%3A279-288 https://pbn.nauka.gov.pl/works/670229 Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011–2014 http://journal.rsw.edu.pl/index.php/JHS/issue/archive Deklaracja. Specyfika i zawartość merytoryczna czasopisma nie ulega zmianie. Zgodnie z informacją MNiSW z dnia 2 czerwca 2014 r., że w roku 2014 nie będzie przeprowadzana ocena czasopism naukowych; czasopismo o zmienionym tytule otrzymuje tyle samo punktów co na wykazie czasopism naukowych z dnia 31 grudnia 2014 r. The journal has had 5 points in Ministry of Science and Higher Education of Poland parametric evaluation. Part B item 1089. (31.12.2014). © The Author (s) 2015; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland and Radom University in Radom, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 25.09.2015. Revised 25.10.2015. Accepted: 10.11.2015. Этиопатогенетические, психопатогенетические и клинические аспекты когнитивных нарушений при сахарном диабете 2-го типа ETIOPATHOGENIC, PSYCHOPATHOGENETIC AND CLINICAL ASPECTS OF COGNITIVE DISORDERS IN TYPE 2 DIABETES О. В. Ткаченко О. V. Tkachenko Запорожская медицинская академия последипломного образования Министерства здравоохранения Украины Medical Academy for Post-Diploma Training of Doctors of the Ministry of Health care of Ukraine, Zaporozhe Summary Etiopathogenetic, psychopathogenetic and clinical aspects of cognitive impairments in type 2 diabetes patients have been analyzed and systematized. Etiopathogenetic and psychopathologic classification of cognitive disorders in the group under study is presented. Comorbid cognitive mental disorders for which cognitive impairment is a factor of amplification are detached. Morphological phenomena associated with cognitive insufficiency in the patients under study has been marked. The main tactics for cognitive insufficiency prevention and therapy in type 2 diabetes patients are considered. Key words: type 2 diabetes, cognitive impairment, mental pathology. Реферат В статье проанализированы и систематизированы этиопатогенетические, психопатогенетические и клинические аспекты когнитивных нарушений при СД 2-го типа. Приведена этиопатогенетическая и психопатологическая классификация когнитивных нарушений при СД 2-го типа. Рассмотрены коморбидные когнитивным психические расстройства, для которых когнитивные нарушения выступают фактором амплификации. Выделены ассоциированные с когнитивной недостаточностью морфологические феномены у пациентов с СД 2-го типа. Рассмотрены основные тактики профилактики и терапии когнитивной недостаточностью у пациентов с СД 2-го типа. Ключевые слова: сахарный диабет 2-го типа, когнитивные нарушения, психическая патология

    Dominating Set, Independent Set, Discrete k-Center, Dispersion, and Related Problems for Planar Points in Convex Position

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    Given a set P of n points in the plane, its unit-disk graph G(P) is a graph with P as its vertex set such that two points of P are connected by an edge if their (Euclidean) distance is at most 1. We consider several classical problems on G(P) in a special setting when points of P are in convex position. These problems are all NP-hard in the general case. We present efficient algorithms for these problems under the convex position assumption. ● For the problem of finding the smallest dominating set of G(P), we present an O(knlog n) time algorithm, where k is the smallest dominating set size. We also consider the weighted case in which each point of P has a weight and the goal is to find a dominating set in G(P) with minimum total weight; our algorithm runs in O(n³log² n) time. In particular, for a given k, our algorithm can compute in O(kn²log² n) time a minimum weight dominating set of size at most k (if it exists). ● For the discrete k-center problem, which is to find a subset of k points in P (called centers) for a given k, such that the maximum distance between any point in P and its nearest center is minimized. We present an algorithm that solves the problem in O(min{n^{4/3}log n+knlog² n,k² nlog²n}) time, which is O(n²log² n) in the worst case when k = Θ(n). For comparison, the runtime of the current best algorithm for the continuous version of the problem where centers can be anywhere in the plane is O(n³ log n). ● For the problem of finding a maximum independent set in G(P), we give an algorithm of O(n^{7/2}) time and another randomized algorithm of O(n^{37/11}) expected time, which improve the previous best result of O(n⁶log n) time. Our algorithms can be extended to compute a maximum-weight independent set in G(P) with the same time complexities when points of P have weights. - If we are looking for an (unweighted) independent set of size 3, we derive an algorithm of O(nlog n) time; the previous best algorithm runs in O(n^{4/3}log² n) time (which works for the general case where points of P are not necessarily in convex position). - If points of P have weights and are not necessarily in convex position, we present an algorithm that can find a maximum-weight independent set of size 3 in O(n^{5/3+δ}) time for an arbitrarily small constant δ > 0. By slightly modifying the algorithm, a maximum-weight clique of size 3 can also be found within the same time complexity. ● For the dispersion problem, which is to find a subset of k points from P for a given k, such that the minimum pairwise distance of the points in the subset is maximized. We present an algorithm of O(n^{7/2}log n) time and another randomized algorithm of O(n^{37/11}log n) expected time, which improve the previous best result of O(n⁶) time. - If k = 3, we present an algorithm of O(nlog² n) time and another randomized algorithm of O(nlog n) expected time; the previous best algorithm runs in O(n^{4/3}log² n) time (which works for the general case where points of P are not necessarily in convex position)
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