43,912 research outputs found
Seminário sobre aquacultura 14 a 16 de dezembro de 1983
A necessidade de desenvolver a aquacultura em Portugal obriga à escolha das espécies mais indicadas para tal finalidade. A propósito o autor chama a atenção para as graves consequências que podem advir das introduções e/ou transferências de animais aquáticos, quer para as espécies locais e meio ambiente, como para a para a saúde pública.Concerning the need to choose the most convenient species to cultivate in order to implement aquaculture in Portugal, the author draws the attention to the deleterious consequences of introductions and transfers of aquatic animals.Caixa Geral de Depósito
Redox-Responsive Nanocapsules for the Spatiotemporal Release of Miltefosine in Lysosome: Protection against Leishmania
Leishmaniasis, a vector-borne disease, is caused by intracellular parasite Leishmania donovani. Unlike most intracellular pathogens, Leishmania donovani are lodged in parasitophorous vacuoles and replicate within the phagolysosomes in macrophages. Effective vaccines against this disease are still under development, while the efficacy of the available drugs is being questioned owing to the toxicity for nonspecific distribution in human physiology and the reported drug-resistance developed by Leishmania donovani. Thus, a stimuli-responsive nanocarrier that allows specific localization and release of the drug in the lysosome has been highly sought after for addressing two crucial issues, lower drug toxicity and a higher drug efficacy. We report here a unique lysosome targeting polymeric nanocapsules, formed via inverse mini-emulsion technique, for stimuli-responsive release of the drug miltefosine in the lysosome of macrophage RAW 264.7 cell line. A benign polymeric backbone, with a disulfide bonding susceptible to an oxidative cleavage, is utilized for the organelle-specific release of miltefosine. Oxidative rupture of the disulfide bond is induced by intracellular glutathione (GSH) as an endogenous stimulus. Such a stimuli-responsive release of the drug miltefosine in the lysosome of macrophage RAW 264.7 cell line over a few hours helped in achieving an improved drug efficacy by 200 times as compared to pure miltefosine. Such a drug formulation could contribute to a new line of treatment for leishmaniasis.A. Das acknowledges SERB (India) Grants (CRG/2020/000492 and JCB/2017/000004) and DBT Grant (BT/PR22251/NNT/28/1274/2017) for supporting this research. N. Mukherjee acknowledges SERB (India) Grant PDF/2016/001437 and K. Das acknowledges the grant EMR/2015/001674 for supporting this research. Financial support from DST (DST/INSPIRE/03/2017/002477) is acknowledged by R.T. This manuscript bears CSMCRI registration no 7/2021.Pramanik, SK (corresponding author), CSIR Cent Salt & Marine Chem Res Inst, Bhavnagar 364002, Gujarat, India.
Mukherjee, N (corresponding author), CSIR Indian Inst Chem Biol, Canc Biol & Inflammatory Disorder Div, Kolkata 700032, India.
Chattopadhy, S (corresponding author), BITS Pilani, Pilani 403726, Goa, India.
Das, A (corresponding author), Indian Inst Sci Educ & Res Kolkata, Mohanpur 741246, W Bengal, India.
[email protected]; [email protected]; [email protected]
Interview with Indra Das
Indra Das is most well-recognized as the author of The Devourers (2015), a novel that won the Lambda Literary Award for straddling the genres of sci-fi, speculative, and fantasy fiction alongside LGBT themes. Das’s short fiction is widely published is horror and sci-fi anthologies, as well as magazines like Tor.com, Strange Horizons, and Asimov’s Science Fiction. He spoke candidly with Alok Amatya over email about the current literary landscape, the work of writing transgressive genre fiction, and his own experiences as an upcoming global author
"PULS." - Ein Blog als Online-Magazin für Medizinstudierende der Goethe-Universität Frankfurt
Im Herbst 2009 forderten Studierende im Rahmen landesweiter Proteste auch am Fachbereich Medizin/Zahnmedizin der Goethe-Universität Frankfurt mehr Transparenz und Kommunikation zu Angelegenheiten ihres Studiums. Einen innovativen Lösungsansatz, um diesen Forderungen nachzukommen, bietet eines der Web 2.0 Werkzeuge: ein auf einer Blog-Software basierendes Online-Magazin für Studierende und andere Mitglieder des Fachbereichs.
Das öffentlich zugängliche Online-Magazin "PULS." (https://newsmagazin.puls.med.uni-frankfurt.de/wp/) wird mit einer freien Blog-Software (wordpress Version 3.1.3.) realisiert und von einer Online-Redakteurin konzipiert und geschrieben. Die Beiträge entstehen nach eigenen Recherchen sowie aus Anregungen und Gesprächen mit verschiedenen Personengruppen des Fachbereichs. Die datenschutzkonforme Auswertung der Zugriffe erfolgt über eine open-source Webanalyse-Software (Piwik). Zusätzlich werden jährlich mit dem Online-Umfrage-Tool Survey Monkey die Nutzer anonym befragt.
"PULS." ist seit dem 14.02.2010 ununterbrochen online und hat seitdem 806 Beiträge (Stand: 27.11.2012) publiziert und wird von ca. 2400 Besuchern monatlich gelesen. Das Themenspektrum ist zentriert auf die Anliegen der Frankfurter Medizin- und Zahnmedizinstudierenden. Die enge Zusammenarbeit mit verschiedenen Gruppierungen des Fachbereichs – Dekanat, Studierende und Lehrende – garantiert darüber hinaus ein fachbereichs-relevantes Themenspektrum. Das Online-Magazin begleitet komplexe Projekte und Entscheidungen mit Hintergrundinformationen und kommuniziert sie verständlich. Eine jährliche Nutzer-Evaluierung zeigt eine wachsende Leserzahl und eine sehr hohe Zustimmung für das Online-Magazin, seine Inhalte und seinen Stil. Das Web 2.0-Medium "Blog" und seine web-typische Sprache entsprechen dem Medienverhalten der Zielgruppe, d.h. den Studierenden des Fachbereichs Medizin.
"PULS." hat sich als ein geeignetes und strategisches Instrument erwiesen, um größere Transparenz, mehr Kommunikation und letztendlich eine stärkere Identifikation der Studierenden mit ihrem Fachbereich voranzutreiben
Die Türkei und das andere Europa : Phantasmen der Identität im Beitrittsdiskurs /
Diese Studie analysiert das dialogische Zusammenspiel zwischen den europäischen und türkischen Diskursen um den möglichen EU-Beitritt der Türkei. Die Differenzen stellen in der Perspektive postkolonialer Theorien ein ambivalentes und formatives Moment für die Bildung einer europäischen Identität dar: Die Europäer nehmen die Beitrittsverhandlungen zum Anlass, über ihr Selbstverständnis zu reflektieren, wobei diverse Ost-West-Repräsentationen kommuniziert und strukturiert werden. Die muslimischen Migranten in Europa und die Minderheiten in der Türkei fungieren dabei als interne Symptome, die die Unvollständigkeit der europäischen bzw. türkischen Identitäten sichtbar machen.Diese Studie analysiert das dialogische Zusammenspiel zwischen den europäischen und türkischen Diskursen um den möglichen EU-Beitritt der Türkei. Die Differenzen stellen in der Perspektive postkolonialer Theorien ein ambivalentes und formatives Moment für die Bildung einer europäischen Identität dar: Die Europäer nehmen die Beitrittsverhandlungen zum Anlass, über ihr Selbstverständnis zu reflektieren, wobei diverse Ost-West-Repräsentationen kommuniziert und strukturiert werden. Die muslimischen Migranten in Europa und die Minderheiten in der Türkei fungieren dabei als interne Symptome, die die Unvollständigkeit der europäischen bzw. türkischen Identitäten sichtbar machen.Bülent Küçük (Dr. phil.) ist Soziologe und arbeitet im Forschungsprojekt "Eurosphere" an der Sabancà Universität in Istanbul. Seine Forschungsschwerpunkte sind Öffentlichkeits-, Diskurs- und Postkoloniale Theorien.Online resource; title from PDF title page (publisher's Web site, viewed October 7 2015).Includes bibliographical references.JSTO
Climate and anthropogenic change in aquatic environments: A cross ecosystem perspective
The chapter, "Climate and anthropogenic change in aquatic environments: A cross ecosystem perspective" was written by the listed authors including Jessica L. Clasen (Douglas College Faculty). The Ecological Dissertations in the Aquatic Sciences (Eco-DAS) symposia bring together 35-40 recent PhD recipients for one week in alternate years. Eco-DAS VIII was held in 2008. Eco-DAS is sponsored by the Center for Microbial Oceanography: Research and Education (C-MORE), the University of Hawai`i School of Ocean and Earth Science and Technology (SOEST) and its Department of Oceanography, and the Association for the Sciences of Limnology and Oceanography (ASLO). The Proceedings of Eco-DAS VIII includes nine chapters published in open access.
In an effort to foster collaboration among researchers across diverse ecosystems, a group of early career scientists whose interests span the aquatic sciences, convened at the University of Hawai’i to participate in the 2008 Eco-DAS symposium. During a break out session of the symposium in which participants were charged with discussing how to best approach mitigation of climate and anthropogenic threats to aquatic ecosystems, participants concluded that effective mitigation will depend upon prioritizing threats across ecosystems. These priorities were documented using a thought experiment in which participants defined their ecosystem of expertise, and then ranked the highest-priority threats to them. Results revealed that marine (open ocean, deep sea, coastal oceans, and rocky intertidal) researchers ranked climate-related impacts (i.e., temperature and ocean acidification) as the highest priority threats whereas estuarine, marsh, wetland, stream, and lake/reservoir researchers ranked the direct anthropogenic impacts of land-use change and nutrient inputs (eutrophication) highest. With such a diverse group, it became apparent that working across ecosystems is limited by issues rang- ing from a lack of large-scale, long-term monitoring to provide baseline data, to broader questions of how changes in one ecosystem cascade across interconnected ecosystems. Here we summarize the discussions, offer insight into the rankings for specific ecosystems, and propose ideas of how past, current, and future research can be used to support a cross-ecosystem perspective on climate and anthropogenic change.book chapterPublished
Structural and Optical Properties of Undoped and Doped ZnO Nanorods
Having unique physical and chemical properties, nanostructures of ZnO become the center of interest for their potential uses in electronic as well as in biomedical applications. In this project, effects of size and doping on structural and physical properties of ZnO nanorods are studied to address this question. Both magnetic cobalt and nonmagnetic magnesium elements are used to study doping effect on ZnO nanorods. All nanorods were synthesized by hydrothermal process. Structural properties of pure and doped ZnO nanorods were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and Raman spectroscopy. Optical properties have been investigated using photoluminescence (PL) spectroscopy. The size of the synthesized nano-rods can be varied from 150 nm to 5 μm. XRD data show that there is no apparent change in lattice parameters with variation in sizes and shapes. However, these affect the optical vibrational modes of the crystal structure as well as the optical properties. PL data show that in general band gap increases and intensity of defect peak in the visible region increases with decreasing nanorod size. XRD and Raman spectroscopy data indicate that there is a small variation in lattice parameter with doping. PL data show that the band gap can be changed with both Co and Mg doping. The intensity of defect peak in the visible region decreases with Mg doping and increases with Co-doping. All the results indicate that Co and Mg doping on ZnO nanorods may provide suitable nanomaterials for future electronic and biomedical applications
Beyond the heatwave: evaluating urban green spaces’ influence on thermal comfort and climate perceptions in Chittagong City, Bangladesh
Formålet med denne studien er å undersøke urban termisk komfort i Chittagong City, Bangladesh, og undersøke hvordan ulike miljøfaktorer påvirker innbyggernes oppfatninger av komfort. I en raskt voksende, tettbefolket by som opplever sterkere og hyppigere hetebølger på grunn av klimaendringer, er forståelse av termisk komfort avgjørende for bærekraftig byplanlegging og folkehelse. Studien brukte en tilnærming med blandede metoder som kombinerer data om mikroklimatiske forhold med funn samlet fra selvrapporteringsundersøkelser administrert til 145 respondenter i ulike miljøer: grønne områder, industriområder og kommersielle områder.
Resultatene avslører forskjeller i termisk komfort på tvers av urbane områder, med høyere ubehag i industriområder som CEPZ og Bayezid sammenlignet med kjøligere grønne områder som CRB og DC Hill, på grunn av den mindre kjølende effekten av disse arealbrukstypene sammenlignet med grønne områder. Fuktighet og luftbevegelse fremsto som nøkkelfaktorer i bioklimatisk design for subtropiske klimaer, og fremhever det komplekse forholdet mellom mennesker og miljø. Mange respondenter tilpasset seg varmestress ved å justere sine utendørsaktiviteter, for eksempel ved å søke skygge eller endre rutinene sine. Statistiske analyser fremhever betydelige sammenhenger mellom demografiske faktorer og komfortnivåer. Historiske temperaturdata fra Bangladeshs meteorologiske avdeling ble analysert for å identifisere trender de siste 15 årene, og avslører en gradvis økning i temperaturer, i tråd med bredere globale oppvarmingstrender.
Studien fremhever beskyttelse og tilgjengelighet av urbane grønne områder for å styrke deres rolle som et viktig verktøy for å redusere effekten av UHI, noe som gir termisk komfort for innbyggerne. Den langsiktige påvirkningen av klimaendringer på urban termisk komfort utgjør et viktig forskningsfelt for fremtiden, i tillegg til innovative strategier for å forbedre levekårene i raskt voksende tropiske og subtropiske byer.
Oppsummert bidrar forskningen til den bredere diskusjonen om urban termisk komfort ved å dokumentere bevis på lignende urbane forhold som de som finnes i mange utviklede byer, og støtter argumentet for bærekraftige planleggingsmetoder som tar hensyn til miljøhelse og livskvalitet i møte med klimaendringenes påvirkning.The purpose of this study is to investigate the urban thermal comfort in Chittagong City, Bangladesh and examine how different environmental factors influence people’s perceptions of comfort. In a fast-growing, crowded city facing stronger, more frequent heat waves due to climate change, understanding thermal comfort is crucial for sustainable city planning and public health. The study used a mixed-methods approach that combines data on microclimatic conditions with findings gathered from self-report surveys administered to 145 respondents in various environments: green spaces, industrial zones and commercial areas.
The results reveal differences in thermal comfort across urban areas, with higher discomfort in industrial zones like CEPZ and Bayezid compared to cooler green spaces like CRB and DC Hill, because of the lesser cooling effect of these land use types when compared to green. Humidity and air movement emerged as key factors in bioclimatic design for subtropical climates, highlighting the complex human-environment relationship. Many respondents adapted to heat stress by adjusting their outdoor activities, such as seeking shade or altering their routines. Statistical analyses underscore significant associations between demographic factors and comfort levels. Historical temperature data from the Bangladesh Meteorological Department was analyzed to identify trends over the past 15 years, revealing a gradual rise in temperatures, consistent with broader global warming patterns.
The study highlights the protection and availability of urban green spaces in order to reinforce its role as a major tool in reducing the effect of UHI causing thermal comfort for citizens. More long-term impact of climate change on urban thermal comfort as field of great concern for future research, additionally innovative strategies to enhance the livability of rapidly growing tropical and subtropical cities.
In sum, the research adds to the broader conversation on urban thermal comfort by documenting evidence of similar urban conditions as those found in many developed cities and supporting the argument for sustainable planning methods that account for environmental health and quality of life as climate change impacts
The vulnerability of ecosystem trophic dynamics to anthropogenically induced environmental change: A comparative approach
The chapter, "The vulnerability of ecosystem trophic dynamics to anthropogenically induced environmental change: A comparative approach" was written by the listed authors including Jessica L. Clasen (Douglas College Faculty).
The Ecological Dissertations in the Aquatic Sciences (Eco-DAS) symposia bring together 35-40 recent PhD recipients for one week in alternate years. Eco-DAS VIII was held in 2008. Eco-DAS is sponsored by the Center for Microbial Oceanography: Research and Education (C-MORE), the University of Hawai`i School of Ocean and Earth Science and Technology (SOEST) and its Department of Oceanography, and the Association for the Sciences of Limnology and Oceanography (ASLO). The Proceedings of Eco-DAS VIII includes nine chapters published in open access.
We employed a comparative approach to review the vulnerability of the trophic interactions within aquatic systems to global threats associated with anthropogenic activities. The goal of this chapter was to identify and characterize mechanisms by which human-mediated environmental threats may modulate trophic dynamics across aquatic ecosystems. Trophic dynamics include some of the most obvious and pervasive factors influencing ecosystems and were used as a metric because of their importance and commonality across all aquatic environments. Our use of trophic dynamics proved to be insightful, illustrating that the flow of energy through aquatic food webs will be (or already has been) altered by invasive species, land-use change, nutrient loading, exposure to ultraviolet radiation, overharvesting, acidification, and increasing global temperatures. The response of trophic dynamics to these threats was often similar across oceans, estuaries, lakes, and rivers. This similarity proved to be interesting given the differences in both the level of concern expressed by scientists and the predicted variability in environment-specific responses. As the trophic interactions of an ecosystem are at the root of its function and structure, examining trophic dynamics could be an informative method for evaluating the response of aquatic environments to global threats. If future analyses validate the use of trophic dynamics as a metric, it is our hope that trophic dynamics can be used by scientists and politicians to mitigate the effects of human actions.book chapterPublished
Article and Author Level Measurements
Article and author level measurements have been discussed in this Unit. Author and researcher identifiers are absolutely essential for searching databases in the WWW because a name like D Singh can harbour a number of names such as Dan Singh, Dhan Singh, Dhyan Singh, Darbara Singh, Daulat Singh, Durlabh Singh and more. The ResearcherID.com, launched by Thomson Reuters, is a web-based global registry of authors and researchers that individualises each and every name. Open Researcher and Contributor ID (ORCID) is also a registry that uniquely identifies an author or researcher. Both have been discussed in this Unit. Article Level Metrics (Altmetrics) has been treated in this Unit with the discussion as to how altmetrics can be measured with Altmetric.com and ImpactStory.org. Altmetrics for Online Journals has also been touched. There are a number of academic social networks of which ResearchGate.net, Academia.edu, GetCited.org, etc. have been discussed. Regional journal networks with bibliometric indicators are also in existence. Two networks of this type such as SciELO – Scientific Electronic Library Online, and Redalyc have been dealt with. This Unit discusses in details aspects such as Unique Identifiers for Authors and Researchers; Article Level Metrics (Altmetrics); Academic Social Networks; and Regional Journal Networks with Bibliometric Indicators
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