348 research outputs found
Association between Bone Mineral Density and Oral Frailty on Renal Function: Findings from the Shika Study
No full text金沢大学博士(医学)博士論文 要旨Abstract/本文Full 以下に掲載：Healthcare 11(3) pp.314-325 2023. MDPI. 共著者：Shingo Nakai, Fumihiko Suzuki, Shigefumi Okamoto, Sakae Miyagi, Hiromasa Tsujiguchi, Akinori Hara, Thao Thi Thu Nguyen, Yukari Shimizu, Koichiro Hayashi, Keita Suzuki, Tomoko Kasahara, Masaharu Nakamura, Chie Takazawa, Takayuki Kannon, Atsushi Tajima, Hirohito Tsuboi, Noriyoshi Ogino, Tadashi Konoshita, Toshinari Takamura, Hiroyuki Nakamuradoctoral thesi
Evaluation of Post-license Advanced Driver Training in Italy
No full textAbstractPost-license advanced driver training addresses different categories of road users such as: novice drivers, professional drivers, company employers and recidivists. These training courses can be carried out on-track or on the road. On-track courses allow participants to gain knowledge on driving physics and experience limits in a safe road environment. On-road courses are more focused on hazard perception and situation awareness.Although extensive research has been done in this field, knowledge of the effects of these courses on road accident risk remains unclear. Previous evaluation of on-track courses did not always show a positive effect on crash rate. For example, post-license training focused on mastery of driving skills can lead to an increase of accident risk, especially on young males.However, research identified several factors that may enhance the effectiveness of driving training. In Europe a new framework for driver education and training has been proposed based on a safe driver hierarchical model (the GADGET model) and the development of a strategy for continuous learning.According to this framework, an evaluation study of on-track post-license advanced driver training has been undertaken in Italy with the main goal of assessing the safety effects of these courses and identifying training aspects to be improved. Besides crash rate, the study aims at assessing also driver behavior, knowledge of risks, self-evaluation and training quality.This paper presents the results of the possible effects of advanced driver training on driving behavior, considering in particular the number and type of violations. For each driver, data on age, gender and driving violations history were extracted from the platform and the national violations database.Three cases were addressed through a before-after analysis with control group. Case 1 considers all drivers who attended an ADT course. Case 2 aimed at understanding the effects of the courses on a specific target group: the traffic violators. Case 3 is similar to Case 2, however the control group was selected in a way that drivers characteristics and the violation rate was similar to the violation rate of the treatment group in the before period.The significance of the differences highlighted was assessed through appropriate statistical tests (i.e. paired t-test and the Wilcoxon signed-rank test).The study showed in general a higher propensity to commit traffic violations after attending an ADT course. These results are in contrast to what expected and show the necessity to diversify the training classes according to the different needs of participants
Relationship between fatty acid intake and chronic neck/shoulder/upper limb pain without elevated CRP in a Japanese population: a cross-sectional analysis of the Shika study
No full text博士論文 要旨Abstract/本文Full 以下に掲載：Journal of Nutritional Science 11(38) pp.1-8 2022. Cambridge University Press. 共著者：Atsushi Asai, Fumihiko Suzuki, Hiromasa Tsujiguchi, Akinori Hara, Sakae Miyagi, Takayuki Kannon, Keita Suzuki, Masaharu Nakamura, Yukari Shimizu, Thao Thi Thu Nguyen, Kim Oanh Pham, Tomoko Kasahara, Shingo Nakai, Koichiro Hayashi, Aki Shibata, Takashi Amatsu, Tadashi Konoshita, Yasuhiro Kambayashi, Hirohito Tsuboi, Atsushi Tajima, Hiroyuki Nakamur
A methodology to assess pedestrian crossing safety
No full textPurpose: The safety level of a pedestrian crossing is affected by infrastructure characteristics and vehicular and pedestrian traffic level. This paper presents a methodology that allows assessing the safety level of a pedestrian crossing, regulated or not by traffic light, in an urban area according to the features of the crossing. Methods: A hierarchical structure representing factors influencing crossing safety has been developed and the relative contributions of each factor were calculated using AHP method. A composite index for crossing safety and specific indexes for main aspects included in the assessment have been developed. Results: Main assessment aspects are: Spatial and Temporal Design, Day-time and Night-time Visibility and Accessibility. Night-time Visibility resulted to have the higher weight (about 41%). Conclusion: Developed indexes allow ranking of pedestrian crossings and assigning intervention priorities, highlighting the aspects which are to be enhanced. The methodology has been used for the evaluation of 215 pedestrian crossings in 17 European cities for the Pedestrian Crossing Assessment Project co-financed by FIA Foundation. © 2010 The Author(s)
Relationship between fatty acid intake and chronic neck/shoulder/upper limb pain without elevated CRP in a Japanese population: a cross-sectional analysis of the Shika study
No full text金沢大学博士(医学）博士論文 要旨Abstract/本文Full 以下に掲載：Journal of Nutritional Science 11(38) pp.1-8 2022. Cambridge University Press. 共著者：Atsushi Asai, Fumihiko Suzuki, Hiromasa Tsujiguchi, Akinori Hara, Sakae Miyagi, Takayuki Kannon, Keita Suzuki, Masaharu Nakamura, Yukari Shimizu, Thao Thi Thu Nguyen, Kim Oanh Pham, Tomoko Kasahara, Shingo Nakai, Koichiro Hayashi, Aki Shibata, Takashi Amatsu, Tadashi Konoshita, Yasuhiro Kambayashi, Hirohito Tsuboi, Atsushi Tajima, Hiroyuki Nakamuradoctoral thesi
Strategies to enhance long-term competitiveness in the telecommunications industry : lessons for NTT
No full textThesis: S.M. in Engineering and Management, Massachusetts Institute of Technology, Engineering Systems Division, 2014.Cataloged from PDF version of thesis.Includes bibliographical references (pages 73-75).In the telecommunications industry, the market is highly global as well as competitive in this era of Internet and data communications. Telecommunications carriers compete with not only other telecommunications carriers providing broadband access and mobile communication but also network application and service providers, which are significant threats for telecommunications carriers. It is difficult for telecommunications carriers to control the market for two significant reasons. Firstly, due to the maturity of technology as well as customers, network services have become commoditized. Secondly, telecommunications network services are vulnerable to over-the-top services based on the Internet. This study aims to investigate how large telecommunications carriers can continue to be competitive in such an environment. This paper focuses on three kinds of strategic options that enable large high-tech companies to continue to make profits; internal R&D, growth and diversification, and M&A. In the second chapter the author focuses on IBM and Cisco, which are good examples of how large companies have evolved over time, combining these three strategies. Then, the use of the three strategies by major telecommunications carriers is investigated. Finally, in the fourth chapter, the author analyzes the future competitiveness of the NTT Group, the major telecommunications carrier in Japan, using these strategies within the next decade.by Shingo Kawai.S.M. in Engineering and Managemen
Well Leg Compartment Syndrome after Cystectomy in the Lithotomy Position: A Case Report
No full textWell leg compartment syndrome (WLCS) is an uncommon and severe complication that occurs after prolonged surgery in the lithotomy position. A 67-year-old male with bladder cancer who underwent cystectomy including ileal conduit construction in the lithotomy position developed severe, gradually worsening cramping pain in the right leg on the day after surgery. The posterior compartmental pressure of the right leg was high (40 mmHg), and WLCS was diagnosed. Emergency fasciotomy was followed by rehabilitation for one month and he recovered from motor or sensory deficits, but the pain continued. We considered that important factors associated with the development of WLCS in this patient were arteriosclerosis obliterans and the length of time during which he remained in the lithotomy position during the ileal conduit procedure. We consider thatlengthy surgical procedures for cystectomy with patients in the lithotomy position have high potential for inducing WLCS
137 Multi-scale FE analysis of rubber friction using rate- and state-dependent friction model
No full textThe H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts
No full textHere we report the new features and improvements in our latest release of the H-Invitational Database (H-InvDB; http://www.h-invitational.jp/), a comprehensive annotation resource for human genes and transcripts. H-InvDB, originally developed as an integrated database of the human transcriptome based on extensive annotation of large sets of full-length cDNA (FLcDNA) clones, now provides annotation for 120 558 human mRNAs extracted from the International Nucleotide Sequence Databases (INSD), in addition to 54 978 human FLcDNAs, in the latest release H-InvDB_4.6. We mapped those human transcripts onto the human genome sequences (NCBI build 36.1) and determined 34 699 human gene clusters, which could define 34 057 (98.1%) protein-coding and 642 (1.9%) non-protein-coding loci; 858 (2.5%) transcribed loci overlapped with predicted pseudogenes. For all these transcripts and genes, we provide comprehensive annotation including gene structures, gene functions, alternative splicing variants, functional non-protein-coding RNAs, functional domains, predicted sub cellular localizations, metabolic pathways, predictions of protein 3D structure, mapping of SNPs and microsatellite repeat motifs, co-localization with orphan diseases, gene expression profiles, orthologous genes, protein–protein interactions (PPI) and annotation for gene families. The current H-InvDB annotation resources consist of two main views: Transcript view and Locus view and eight sub-databases: the DiseaseInfo Viewer, H-ANGEL, the Clustering Viewer, G-integra, the TOPO Viewer, Evola, the PPI view and the Gene family/group
Widespread imiquimod-induced psoriasis like eruption: case report and analysis of mast cell infiltration.
No full textPsoriasis is an inflammatory skin disease that affects over 60 million adults and children worldwide.1 Many genetically innovative and easy-to-use models have been generated to study psoriasiform skin inflammation in mice. Topical application of imiquimod, the agent with immune response modifying activity, is widely used for psoriasis research. A Previous study demonstrated that mast cells (MCs) increase in imiquimod-induced psoriasis in mice.2 Topical application of imiquimod is used to treat actinic keratosis and condyloma acuminatum. Several cases of psoriasis-like eruptions caused by topical imiquimod have been reported. These eruptions are distinct from psoriasis. Moreover, psoriasis-like eruptions observed in areas other than the topical imiquimod site.3 Herein, we report a case of psoriasis like eruptions after topical imiquimod treatment. In previous studies, upregulation in the number and activation of MCs has been found in imiquimod-induced psoriasis in mice. 2 Mast cell infiltration has been found in patients with psoriasis.2 However, mast cell infiltration and the number of MCs in imiquimod-induced psoriasis in humans is unclear. We investigated the number of MCs in our case for a better understanding the mechanism of imiquimod-induced psoriasis like eruption.Tatsuya Katsumi, Ryota Hayashi, Shingo Takei, Manon Okamura, Yuka Tsutsui, Osamu Ansai, Akito Hasegawa, Yu Matsui, Tatsuya Takenouchi, Riichiro Abe, Widespread imiquimod-induced psoriasis-like eruption: case report and analysis of mast cell infiltration, Clinical and Experimental Dermatology, Volume 50, Issue 6, June 2025, Pages 1221–1224, https://doi.org/10.1093/ced/llae527This is a pre-copyedited, author-produced version of an article accepted for publication in Clinical and Experimental Dermatology following peer review.
The version of record, Tatsuya Katsumi, Ryota Hayashi, Shingo Takei, Manon Okamura, Yuka Tsutsui, Osamu Ansai, Akito Hasegawa, Yu Matsui, Tatsuya Takenouchi, Riichiro Abe, “Widespread imiquimod-induced psoriasis-like eruption: case report and analysis of mast cell infiltration,” Clinical and Experimental Dermatology, Volume 50, Issue 6, June 2025, Pages 1221–1224, is available online at: https://doi.org/10.1093/ced/llae527
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