67 research outputs found
Dr. Kristin Bezio – Faculty Author Interview
No full textKristin Bezio, Assistant Professor Of Leadership Studies, discusses “Friends & Rivals: Loyalty, Ethics, and Leadership in Dragon Age II,” a chapter in the 2014 book, Identity and Leadership in Virtual Communities: Establishing Credibility and Influence. Dr. Bezio’s teaching and research focuses on the ways in which literature, drama, film, and video games have influenced society and the way people think about issues of leadership and followership. Her chapter explores how video game players can influence their understanding of ethics in terms of human emotion and interactio
Duobrachium Ford & Bezio & Collin 2020, gen. nov
No full textGenus Duobrachium gen. nov. Diagnosis. Tentaculate cydippid ctenophores with two thick, aboral, conical tentacle arms. Tentacle arms emerge from the center of the body and extend aborally. Body rectangular in the tentacular plane, oblong in the stomodeal plane. The tentacle arms are as long as the body is tall. Tentacles retractile, with simple tentilla of uniform length. Filaments can exit orally, anchoring it to the sediment. Stomodeum darkly pigmented. Gonads globular, not extending the length of the meridional canals. Type species. Duobrachium sparksae n. sp., described herein. Etymology. From the Latin “two-arms”, a name reflecting the two prominent arms. The Latin “brachium” is of common gender, but shall be treated as feminine, in accordance with ICZN article 30.1.4.2.Published as part of Ford, Michael, Bezio, Nicholas & Collin, Allen, 2020, Duobrachium sparksae (incertae sedis Ctenophora Tentaculata Cydippida): A new genus and species of benthopelagic ctenophore seen at 3,910 m depth off the coast of Puerto Rico, pp. 296-305 in Plankton & Benthos research 15 (4) on page 298, DOI: 10.3800/pbr.15.296, http://zenodo.org/record/645801
Fig. 2 in Duobrachium sparksae (incertae sedis Ctenophora Tentaculata Cydippida): A new genus and species of benthopelagic ctenophore seen at 3,910 m depth off the coast of Puerto Rico
No full textFig. 2. Line drawing schematic of Duobrachium sparksae n. gen. n. sp. A. Tentacular view of the main body of the animal. B. Oral view. C. Aboral view. ct - ctene row, g - gonads, m - mouth, ta - tentillum, tent - tentacle, stat - statocyst, sto - stomodeum. Illustrations by NB.Published as part of Ford, Michael, Bezio, Nicholas & Collin, Allen, 2020, Duobrachium sparksae (incertae sedis Ctenophora Tentaculata Cydippida): A new genus and species of benthopelagic ctenophore seen at 3,910 m depth off the coast of Puerto Rico, pp. 296-305 in Plankton & Benthos research 15 (4) on page 300, DOI: 10.3800/pbr.15.296, http://zenodo.org/record/645801
Gender Differences in Young Children's Perceptions of Writing, Writing Characteristics, and Knowledge of Production Rules in Writing
No full textResearch has shown that children come to school with preexisting knowledge about writing. It is therefore essential for teachers to observe their students to learn what knowledge they already possess and to plan their lessons accordingly. The author asks whether there are differences between how boys and girls perceive the writing process, whether there are differences between the characteristics of boys’ and girls’ writing samples and episodes, and whether there are differences between boys’ and girls’ knowledge of production rules in writing. A subject pool of 34 children were selected and were given two interviews in which they completed writing tasks and answered questions from the author. The results of these interviews were collected and analyzed by type of response given. The author found that while many children just beginning school do not yet have a clear definition of writing, more girls than boys seem to have a closer perception of what writing is. Similarly, girls were seemingly more perceptive to the purposes of writing, though a majority of both perceived it as relatively easy. Lastly, the writing tests suggest that girls may obtain knowledge of writing’s production rules sooner than boys. The author argues that further research is needed to verify their findings and to better understand the role of families and teachers in a child’s writing development.SUNY BrockportMaster of Science in Education (MSEd)Education and Human Development Master's These
Critical edition of Camp-Bell, or the Ironmonger’s Fair Field (author, Anthony Munday) with Mapping Early Modern London
No full textShakespeare and his contemporaries traversed London on foot. Early modern plays, pamphlets, histories, and poems assume intimate knowledge of the streets, alleys, and topography of the city. At Map of Early Modern London (MoEML), our ongoing project is to map the spatial imaginary of Shakespeare’s city; we ask how London’s spaces and places were named, traversed, used, repurposed, and contested by various practitioners (Michel de Certeau’s term), writers, and civic officials. MoEML’s maps allow us to plot people, historical documents, literary works, and recent critical research onto topography and the built environment. At the same time, we experiment with new digital modes of answering GeoHumanities questions. An early contributor to the spatial turn and literary geographic information systems (GIS), MoEML provides a virtual space for exploring the meaning and representation of cultural space in the London of Shakespeare and his contemporaries. We also experiment with new ways of working collaboratively as teams and across institutions and disciplines
Effects of capture surface morphology on feeding success of scyphomedusae : a comparative study
No full text© The Author(s), 2018. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Marine Ecology Progress Series 596 (2018): 83-93, doi:10.3354/meps12549.Predation by feeding-current foraging medusae can have detrimental effects on prey populations. Understanding the mechanics that control prey selection and ingestion rates with different types of prey enables us to better predict the predatory impact of these medusae. We quantified the outcomes of each post-entrainment stage of the feeding process in multiple scyphozoan jellyfish species to understand how post-entrainment feeding events influence feeding patterns. Using 3-dimensional video, we observed and quantified the fate of both passive and actively swimming prey that were entrained in the feeding current of 5 different scyphomedusan species belonging to the orders Semaeostomeae and Rhizostomeae. Less than 65% of entrained prey contacted the capture surfaces (termed contact efficiency) of the semaeostome medusae, while the rhizostome medusae came into contact with less than 35% of the prey entrained in the feeding current. However, when contacted, prey were very likely to be ingested (>90%) by all species examined. These results suggest that prey capture by oblate medusae appears to be largely limited by the probability that prey entrained in the feeding current will contact a capture surface. As a passive process, this contact stage of the feeding process is directly affected by the morphology of the contact surfaces. The importance of the contact stage of the feeding process suggests that differences in prey selection patterns observed among oblate medusan taxa are likely dominated by the morphology of contact surfaces as opposed to traits which influence the other stages of the feeding process, i.e. bell shape and nematocysts.This work was funded by a NSF Biological
Oceanography grant awarded to S.P.C. and J.H.C.
(OCE 1536688) and supported by the Roger Williams University
Foundation to Promote Teaching and Scholarship
Critical edition of The triumphs of re-united Britannia (author, Anthony Munday) with Mapping Early Modern London
No full textShakespeare and his contemporaries traversed London on foot. Early modern plays, pamphlets, histories, and poems assume intimate knowledge of the streets, alleys, and topography of the city. At Map of Early Modern London (MoEML), our ongoing project is to map the spatial imaginary of Shakespeare’s city; we ask how London’s spaces and places were named, traversed, used, repurposed, and contested by various practitioners (Michel de Certeau’s term), writers, and civic officials. MoEML’s maps allow us to plot people, historical documents, literary works, and recent critical research onto topography and the built environment. At the same time, we experiment with new digital modes of answering GeoHumanities questions. An early contributor to the spatial turn and literary geographic information systems (GIS), MoEML provides a virtual space for exploring the meaning and representation of cultural space in the London of Shakespeare and his contemporaries. We also experiment with new ways of working collaboratively as teams and across institutions and disciplines
An Investigation of Autoantibodies against Tyrosine Hydroxylase in Patients with Vitiligo
No full textVitiligo is an acquired idiopathic hypomelanotic skin disorder characterised by depigmented macules due to loss of cutaneous melanocytes. Evidence suggests that autoimmunity plays a role in the pathogenesis of the disease, since antibodies and T cells against melanocytes can be detected in vitiligo patients. A major goal in vitiligo research is to identify the targets of the immune response in patients, as this will contribute to defining the pathomechanisms of the disease. A better understanding of vitiligo pathogenesis is required in order to allow the development of better diagnostic, prognostic and therapeutic measures.
Previously, the enzyme tyrosine hydroxylase (TH) was identified as a putative B cell autoantigen in vitiligo using phage-display technology. The aims of the present study were to confirm TH as an antibody target in vitiligo, to investigate the prevalence of TH antibodies and to characterise several properties of TH antibodies.
Firstly, a radioimmunoassay (RIA) with [35S]-labelled TH was used to identify TH antibodies in sera from patients with either non-segmental vitiligo (n=79), segmental vitiligo (n=8) or other autoimmune diseases without concomitant vitiligo (n=91). Sera from healthy individuals (n=28) were also tested. The results indicated that segmental vitiligo patients, healthy subjects and patients with other autoimmune diseases without concomitant vitiligo were all negative for TH antibody reactivity. Of 79 non-segmental vitiligo patients, 18 (23%) were positive for TH antibodies. A significant increase in the prevalence of TH antibodies was evident in the non-segmental vitiligo patient group when compared with healthy participants (P = 0.003). TH antibody prevalence was also significantly elevated in the group of patients with active vitiligo compared to the group with stable disease (P = 0.009): TH antibodies were detected in 18/64 (28%) of patients with active disease, but not in any of the 20 patients with stable vitiligo.
Secondly, the binding sites of TH antibodies were investigated. Initially, the binding domains for TH antibodies on the protein were identified using [35S]-labelled TH protein fragments in RIAs. Further localisation of TH binding sites (epitopes) was carried out in antibody absorption experiments using synthetic TH peptides and non-radiolabelled in vitro expressed TH protein fragments. In addition, antibody binding to the identified TH epitopes was confirmed in TH peptide enzyme-linked immunosorbent assays (ELISA). The results indicated that epitopes for vitiligo patient TH antibodies were located at the N-terminus of TH between amino acids 1 and 14 (epitope 1-14) and between amino acids 61 and 80 (epitope 61-80). Of 18 vitiligo patients, 17 (94%) had antibodies against epitope 1-14, and 11 (61%) displayed immunoreactivity against epitope 61-80. Antibody binding to both epitopes was demonstrated in 10/18 (56%) of vitiligo patients.
Finally, TH peptide (amino acids 1-14 and 61-80) ELISAs were used to determine the subclass and avidity of TH antibodies. The results showed that antibodies against TH epitope 1-14 were exclusively of the IgG1 subclass. Antibody responses against TH epitope 61-80 were also predominantly of the IgG1 subclass with a minority of subclass IgG3. TH antibody binding was also assessed at increasing NaCl concentrations as a measure of antibody avidity. The results suggested that vitiligo patient TH antibodies were of variable avidity towards their antigenic TH peptide target.
Overall, the work in this thesis confirmed TH as an autoantigen in vitiligo, described the prevalence of TH antibodies in a vitiligo patient cohort, and characterised several properties of TH antibodies including epitopes, subclasses and avidities
Measurement of the azimuthal anisotropy of charged particles in TeV OO and NeNe collisions with the ATLAS detector
No full textInternational audienceThis paper presents the first measurements of the azimuthal anisotropy coefficients , which quantify the -order Fourier modulation of charged-particle azimuthal distributions, for -4 in TeV and collisions recorded with the ATLAS detector at the Large Hadron Collider in 2025. The coefficients are measured as a function of transverse momentum (), collision centrality, and event multiplicity. They are extracted using two complementary methods: two-particle correlations with a template-fit subtraction of short-range non-flow contributions, and four-particle subevent cumulants, which intrinsically suppress non-flow effects and provide sensitivity to flow fluctuations. The results show a clear hierarchy and a non-monotonic dependence on , reaching a maximum around 2 GeV, consistent with trends observed in heavy-ion collisions. Detailed comparisons between the two collision systems reveal an enhanced in central collisions, consistent with theory expectations based on the predicted prolate deformation of neon nuclei, in contrast to the slightly tetrahedral structure predicted for oxygen. The four-particle cumulant results highlight strong event-by-event fluctuations and provide the greatest sensitivity to nuclear shape effects. These measurements can place new constraints on the initial geometry and the hydrodynamic response in light-ion collisions, offering valuable input for models of nuclear structure
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