551 research outputs found
sj-docx-1-npx-10.1177_1934578X211031148 - Supplemental material for Antileishmanial Potential of Berberine Alkaloids From <i>Berberis glaucocarpa</i> Roots: Molecular Docking Suggests Relevant <i>Leishmania</i> Protein Targets
No full textSupplemental material, sj-docx-1-npx-10.1177_1934578X211031148 for Antileishmanial Potential of Berberine Alkaloids From Berberis glaucocarpa Roots: Molecular Docking Suggests Relevant Leishmania Protein Targets by Muhammad Alamzeb, Saqib Ali, Mamoon-Ur-Rashid, Behramand Khan, Ihsanullah, Adnan, Muhammad Omer, Asad Ullah, Javed Ali, William N. Setzer, Syed M. Salman, Ajmal Khan and Akram Shah in Natural Product Communications</p
sj-docx-2-npx-10.1177_1934578X211031148 - Supplemental material for Antileishmanial Potential of Berberine Alkaloids From <i>Berberis glaucocarpa</i> Roots: Molecular Docking Suggests Relevant <i>Leishmania</i> Protein Targets
No full textSupplemental material, sj-docx-2-npx-10.1177_1934578X211031148 for Antileishmanial Potential of Berberine Alkaloids From Berberis glaucocarpa Roots: Molecular Docking Suggests Relevant Leishmania Protein Targets by Muhammad Alamzeb, Saqib Ali, Mamoon-Ur-Rashid, Behramand Khan, Ihsanullah, Adnan, Muhammad Omer, Asad Ullah, Javed Ali, William N. Setzer, Syed M. Salman, Ajmal Khan and Akram Shah in Natural Product Communications</p
sj-xlsx-2-npx-10.1177_1934578X221120215 - Supplemental material for Network Pharmacology Analysis of Bioactive Components and Mechanisms of Action of <i>Qi Wei Wan</i> Formula for Treating Non-Small Cell Lung Carcinoma
No full textSupplemental material, sj-xlsx-2-npx-10.1177_1934578X221120215 for Network Pharmacology Analysis of Bioactive Components and Mechanisms of Action of Qi Wei Wan Formula for Treating Non-Small Cell Lung Carcinoma by Minghe Zhang, Ye Wang, Aftab Amin, Muhammad Ajmal Khan, Zhiling Yu and Chun Liang in Natural Product Communications</p
sj-xlsx-1-npx-10.1177_1934578X221120215 - Supplemental material for Network Pharmacology Analysis of Bioactive Components and Mechanisms of Action of <i>Qi Wei Wan</i> Formula for Treating Non-Small Cell Lung Carcinoma
No full textSupplemental material, sj-xlsx-1-npx-10.1177_1934578X221120215 for Network Pharmacology Analysis of Bioactive Components and Mechanisms of Action of Qi Wei Wan Formula for Treating Non-Small Cell Lung Carcinoma by Minghe Zhang, Ye Wang, Aftab Amin, Muhammad Ajmal Khan, Zhiling Yu and Chun Liang in Natural Product Communications</p
sj-docx-4-npx-10.1177_1934578X221120215 - Supplemental material for Network Pharmacology Analysis of Bioactive Components and Mechanisms of Action of <i>Qi Wei Wan</i> Formula for Treating Non-Small Cell Lung Carcinoma
No full textSupplemental material, sj-docx-4-npx-10.1177_1934578X221120215 for Network Pharmacology Analysis of Bioactive Components and Mechanisms of Action of Qi Wei Wan Formula for Treating Non-Small Cell Lung Carcinoma by Minghe Zhang, Ye Wang, Aftab Amin, Muhammad Ajmal Khan, Zhiling Yu and Chun Liang in Natural Product Communications</p
sj-xlsx-3-npx-10.1177_1934578X221120215 - Supplemental material for Network Pharmacology Analysis of Bioactive Components and Mechanisms of Action of <i>Qi Wei Wan</i> Formula for Treating Non-Small Cell Lung Carcinoma
No full textSupplemental material, sj-xlsx-3-npx-10.1177_1934578X221120215 for Network Pharmacology Analysis of Bioactive Components and Mechanisms of Action of Qi Wei Wan Formula for Treating Non-Small Cell Lung Carcinoma by Minghe Zhang, Ye Wang, Aftab Amin, Muhammad Ajmal Khan, Zhiling Yu and Chun Liang in Natural Product Communications</p
Kaempferol as a dietary anti-inflammatory agent: current therapeutic standing
No full textInflammation is a physiological response to different pathological, cellular or vascular damages due to physical, chemical or mechanical trauma. It is characterized by pain, redness, heat and swelling. Current natural drugs are carefully chosen as a novel therapeutic strategy for the management of inflammatory diseases. Different phytochemical constituents are present in natural products. These phytochemicals have high efficacy both in vivo and in vitro. Among them, flavonoids occur in many foods, vegetables and herbal medicines and are considered as the most active constituent, having the ability to attenuate inflammation. Kaempferol is a polyphenol that is richly found in fruits, vegetables and herbal medicines. It is also found in plant-derived beverages. Kaempferol is used in the management of various ailments but there is no available review article that can summarize all the natural sources and biological activities specifically focusing on the anti-inflammatory effect of kaempferol. Therefore, this article is aimed at providing a brief updated review of the literature regarding the anti-inflammatory effect of kaempferol and its possible molecular mechanisms of action. Furthermore, the review provides the available updated literature regarding the natural sources, chemistry, biosynthesis, oral absorption, metabolism, bioavailability and therapeutic effect of kaempferol
د اجمل خټک په شاعرۍ کښې ترقي پسندۍ ته يوه کتنه
No full text Ajmal Khattak was born on September 15, 1925 in Akora Khattak. He was a follower of Bacha Khan and an active leader of the Awami National Party. As a poet and writer, Ajmal Khattak was inspired by the progressive movement. Ajmal Khattak broke the tradition of Pashto poetry for hundreds of years and added class, revolutionary and resistance colors to it. He became very famous as a progressive poet. This article examines his poetry as a progressive poet
Phosphodiesterase-1 inhibitory activity of two flavonoids isolated from pistacia integerrima J. L. Stewart galls
No full textPistacia integerrima is one of twenty species among the genus Pistacia. Long horn-shaped galls that develop on this plant are harvested and used in Ayurveda and Indian traditional medicine to make "karkatshringi", a herbal medicine used for the treatment of asthma and different disorders of respiratory tract. However, until now, the molecular mechanisms of action of "karkatshringi" and its chemical characterization are partially known. This study deals with the isolation and characterization of the active constituents from the methanolic extract of P. integerrima galls and it was also oriented to evaluate in vitro and in silico their potential enzymatic inhibitory activity against phosphodiesterase-1 (PDE1), a well-known enzyme involved in airway smooth muscle activity and airway inflammation. Our results showed that the methanolic extract of P. integerrima galls and some of its active constituents [naringenin (1) and 3,5,7,4'-tetrahydroxy-flavanone (2)] are able in vitro to inhibit PDE1 activity (59.20 +/- 4.95%, 75.90 +/- 5.90%, and 65.25 +/- 5.25%, resp.) and demonstrate in silico an interesting interaction with this enzymatic site. Taken together, our results add new knowledge of chemical constituents responsible for the biological activity of P. integerrima and contextually legitimate the use of this plant in folk medicine
Information and Communication Technology Literacy (ICTL): Skills for Library Professionals in the Digital Era
No full textHighlights the concepts of literacy, information literacy and information and communication technologies (ICTs) and its purpose, scope and appropriateness among library professionals in the 21st century. Discusses the role of library professionals in setting vision towards learning and educating their clients to become ICT literates. Indicates the areas where the ICTs can be applied in library and information centres and the role of library professionals to effectively use their knowledge and skills for the ultimate benefit of the society. Projects the importance of creating awareness on ICT literacy among the user group to enhance the use of services and facilities offered by the library and information centres
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