324,632 research outputs found
Medical and societal consequences of late presentation
No full textPatients presenting late with HIV infection are at a higher risk of clinical events, are difficult to treat and have a higher mortality compared with those who present earlier. Indeed, being diagnosed too late for effective treatment has been shown to be a common scenario leading to death. The increased risk for opportunistic diseases and increased mortality are associated with low CD4+ T-cell counts. In addition to the detrimental effect on the health of the individual, late presentation also creates a significant societal burden because it is associated with increased risk of HIV transmission and increased resource use. All of these factors highlight the benefit of earlier testing, diagnosis and treatment of HIV
Anti-HIV-1 intermittent drug intensification in HIV-1-infected patients naive for antiretrovirals
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New Palaeolithic sites from the Depresión de Monforte de Lemos (Lugo, Galicia, Spain)
No full textEste artículo presenta el descubrimiento de nuevos yacimientos paleolíticos en la Depresión de Monforte
de Lemos (Noroeste de la Península Ibérica). Esta zona fue rellenada con depósitos cuaternarios que han proporcionado más de 30 yacimientos al aire libre. Como consecuencia del descubrimiento casual de artefactos paleolíticos, se
ha desarrollado un proyecto de intervención arqueológica sistemática, que ha demostrado el potencial de esta área.
Muchos de los artefactos líticos han sido hallados en superficie, pero además contamos con dos yacimientos que tienen materiales en contexto estratigráfico (O Regueiral y Áspera). En la Depresión de Monforte hemos atestiguado
poblamiento humano a lo largo del Pleistoceno medio y superior, con implementos líticos clasificados como Modo 2,
Modo 3 y Modo 4. Los yacimientos más importantes son As Lamas, Chao de Fabeiro (ambos con industria lítica de
Modo 2, que incluye bifaces y hendedores), O Regueiral (Modo 3) y Valverde (Modo 4). Por consiguiente, la
Depresión de Monforte reúne las condiciones apropiadas para el desarrollo de un estudio diacrónico sobre la evolución del comportamiento técnico durante el Paleolítico, y su relación con la evolución del medioambiente a lo largo
del PleistocenoThis paper reports the discovery of new Paleolithic sites in the Depresión de Monforte de Lemos (Monforte
Basin, NW of the Iberian Peninsula). This zone was filled with Quaternary deposits that have yielded 30 open air sites.
Due to the casual discovery of Paleolithic artifacts a systematic archaeological work was carried out, assessing the
archaeological potential of this area. Most of these lithic artifacts were found on surface, but also we have located two
sites with archaeological materials in stratigraphic context (O Regueiral and Áspera). In the basin of Monforte we have
recognized a human settlement along the Middle and Upper Pleistocene, with lithic implements classified as Mode 2,
Mode 3 and Mode 4. The most important sites are As Lamas, Chao de Fabeiro (both with Mode 2 lithic industry, that
includes handaxes and cleavers), O Regueiral (Mode 3), and Valverde (Mode 4). Thus the Monforte Basin has the adequate conditions to accomplish a diachronic study on the evolution of the strategies of technical behavior during the
Paleolithic, and its relation with the evolution of Pleistocene environmentEste trabajo se enmarca en el proyecto de investigación “Ocupaciones humanas durante el
Pleistoceno de la Cuenca media del Miño” financiado por el Ministerio de Educación y Ciencia y
fondos FEDER de la UE (HUM2007-63662/HIST)S
Diffusive author(s), cohesive author: Analysis of S/N (1994)
No full textThis study indicates the ways in which various aspects of the author(s) are brought forth in Dumb type’s performance art, the S/N production. Previous research has suggested a non-hierarchical organization of Dumb type and the absence of a “privileged author” in Dumb type’s collaborative work, S/N. However, the results that I have investigated from member’s interviews on the creative process of S/N along with my analysis of the recorded images of S/N, indicate a different aspect of the author(s). First, S/N was created through, so to speak, the collective ideas of the members of Dumb type. Further, S/N has at least nine quotations from previous performances, installations, and printed writings, besides the work-in-progress technique. Explicating one of the “author functions” as given by Michel Foucault, each text has plural subjects of the author. However, it has been revealed from members’ interviews that Teiji Furuhashi had a decision-making role in selecting the members’ ideas within the performance. Since then, S/N has had plural subjects of creation; however, Furuhashi is one of the subjects of creation along with the “privileged author.” S/N has plural authors (diffusive authors) yet at the same time, it has a “privileged author,” Teiji Furuhashi (cohesive author)
Horizontal and Vertical BIM Interoperability Aimed at Seismic Vulnerability Assessment
No full textA vital task of this millennium is to protect the existing heritage, also through the adoption of resilient management systems. In this framework, the organization of knowledge remains one of the critical points. For this reason, new methodologies and cross-disciplinary technologies are increasingly being chosen to optimize resources toward more sustainable interventions. Therefore, the ability to model the building geometry and behavior must be maximized through interoperable processes between Building Information Modeling and Finite Element Modeling methods aimed at the seismic vulnerability assessment. Setting up an integrated digitalization process is undoubtedly challenging initially but returns more significant benefits during the infrastructure life cycle. The interoperability tests' bi-directionality is essential for constantly evaluating activities to update data following facilities' modifications. The Modal Assurance Criterion indicator is used to assess the coherence of the models after possible simplifications introduced for non-linear state analyses
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Peculiar muscle imaging findings in a patient with alphaB-crystallinopathy and axial myopathy
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