58,856 research outputs found

    Menon, U

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    Risk-reducing early salpingectomy and delayed oophorectomy as a two-staged alternative for primary prevention of ovarian cancer in women at increased risk: a commentary.

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    This is the peer reviewed version of the following article: Gaba, F. , Piek, J. , Menon, U. and Manchanda, R. (2019), Risk reducing early salpingectomy and delayed oophorectomy as a two staged alternative for primary prevention of ovarian cancer in increased risk women: a commentary. BJOG: Int J Obstet Gy. Accepted Author Manuscript. doi:10.1111/1471-0528.15651, which has been published in final form at https://doi.org/10.1111/1471-0528.15651. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Version

    A priori and a posteriori analysis of the hybrid two-level large-eddy simulation method for high Reynolds number complex flows

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    We present a priori and a posteriori analysis of the assumptions and predictions of the hybrid two-level large-eddy simulation (TLS-LES) method for high Reynolds number complex flows. The TLS-LES methodology is a multi-scale framework for simulation of turbulent flows in complex configurations at practically relevant Reynolds number. It additively combines the two-level simulation (TLS) model with a conventional large-eddy simulation (LES) approach by employing a static or dynamic blending function. In the present study, first we analyze the model assumptions employed by the TLS model to obtain the small-scale solution necessary for closure of the large-scale equations. Afterward, we analyze the large-scale and small-scale solutions to assess the predictive ability of the multi-scale framework for specific turbulence physics such as role of forward and backscatter of energy and presence of co- and counter-gradient diffusion. To perform these investigations, we consider cases with increasing degree of geometrical complexity, namely, flow in a periodic channel, flow past a bump placed on the lower surface of the channel and flow past a finite-span NACA0015 airfoil

    Evaluering av E6 Østfold. Delprosjektene Åsgård–Halmstad og Svingenskogen–Åsgård, samt samlet Utbygging

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    På oppdrag for forskningsprogrammet Concept ved NTNU1har Menon Economics evaluert E6 i Østfold.Vi har evaluert to delprosjekter, Åsgård–Halmstad og Svingenskogen–Åsgård, samt utbyggingen av E6 samlet. Denne rapporten inneholder en samlet rapportering for alle de tre evalueringene.Målet medoppdraget var å gjennomføre ex post evaluering av vegutbyggingenfor å finne ut hvor vellykket prosjektet ble. Evalueringen er basert på Concepts evalueringsmodell

    Evaluering av E6 Østfold. Delprosjektene Åsgård–Halmstad og Svingenskogen–Åsgård, samt samlet Utbygging

    No full text
    På oppdrag for forskningsprogrammet Concept ved NTNU1har Menon Economics evaluert E6 i Østfold.Vi har evaluert to delprosjekter, Åsgård–Halmstad og Svingenskogen–Åsgård, samt utbyggingen av E6 samlet. Denne rapporten inneholder en samlet rapportering for alle de tre evalueringene.Målet medoppdraget var å gjennomføre ex post evaluering av vegutbyggingenfor å finne ut hvor vellykket prosjektet ble. Evalueringen er basert på Concepts evalueringsmodell.publishedVersio

    Book Review: Management of scombroid fisheries, Edited by N.G.K. Pillai

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    Management of Scombroid Fisheries Editors: N.G.K. Pillai N.G. Menon P.P. PiUai U. Gang

    Equivariant elliptic cohomology and twisted equivariant k-theory

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    Equivariant elliptic cohomology and twisted equivariant K-theory are both related to the representations of loop groups. After making these relationships precise, we propose a map from twisted equivariant elliptic cohomology to twisted K-theory of the inertia stack using equivariant de Rham models. This proposal agrees with the Freed-Hopkins-Teleman q = 1 map from characters of representations of loop groups to distributions associated to twisted equivariant K-theory classes.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2021-08-01The student, Dileep Menon, accepted the attached license on 2019-05-24 at 15:54.The student, Dileep Menon, submitted this Dissertation for approval on 2019-05-24 at 16:06.This Dissertation was approved for publication on 2019-05-28 at 10:50.DSpace SAF Submission Ingestion Package generated from Vireo submission #13991 on 2019-11-26 at 13:00:58Made available in DSpace on 2019-11-26T20:49:00Z (GMT). No. of bitstreams: 4 MENON-DISSERTATION-2019.pdf: 528838 bytes, checksum: fbe8f9b0e3bd2fbc0c4e207d94ba6cdd (MD5) thesis-ex.tex: 116427 bytes, checksum: 1eb2193b9661caa6b07eb1f864882e78 (MD5) thesisbib.bib: 7057 bytes, checksum: 2f604815e6b22de4a7bd0bec92caf53a (MD5) LICENSE.txt: 4209 bytes, checksum: ef4b73600b176b70c7c9713536cda315 (MD5) Previous issue date: 2019-05-28Embargo set by: Seth Robbins for item 112889 Lift date: 2021-11-26T20:49:41Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I Only Restriction Lifted for Item 112889 on 2021-11-27T10:15:09Z

    Not Available

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    Not AvailableManagement of Scombroid Fisheries Editors: N.G.K. Pillai N.G. Menon P.P. PiUai U. GangaNot Availabl

    Ovarian cancer screening in the general population.

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    Despite significant improvements in therapy, ovarian cancer continues to be a leading cause of death amongst women with gynaecological malignancies. Advanced stage at diagnosis is thought to be a major contributor to mortality. Hence, there is considerable interest in early detection through screening. In the 1990s, Professor Jacobs pioneered the development of a multimodal ovarian cancer screening (OCS) strategy using serum CA125 as the first line screen and pelvic ultrasound as the second line test. This thesis summarises the next steps in the journey with refining of the screening algorithm, feasibility testing in a pilot randomised control trial (RCT) and finally setting up and recruiting 200,000 women into the largest ever RCT . The risk of ovarian cancer in postmenopausal women with elevated CA125 levels was established through a detailed analysis of 1219 pelvic scans from 741 women with raised CA125 levels in the completed trial of 22,000 women. Based on this, the multimodal 'Risk of Ovarian Cancer' (ROC) algorithm was refined and morphology instead of volume was used to interpret the ovarian scans. The refined ROC algorithm was then prospectively evaluated in a pilot RCT of 13,582 postmenopausal women. The trial established that screening using the ROC algorithm was feasible and could achieve high specificity and positive predictive value. The improved performance characteristics of the screening strategy and the experience accumulated in running and organising the pilot trial led to the design and successful implementation of a RCT - the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) - to assess the impact of early detection on disease mortality. The trial commenced in 2001 with recruitment of 202,638 postmenopausal women by September 2005. The issues involved in setting up the trial, recruitment of 202,000 women and the baseline characteristics of this population are described

    Plat. Men. 70a-b: Menon

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    In diesem Dialog des Sokrates mit Menon ist das zentrale Thema, ob etwas erlernbar, übbar oder von Natur aus vorhanden ist. Dies wird v. a. anhand der Areté erörtert, wobei das Zitat den Ausgangspunkt darstellt. Die Thessalier werden hier als ob ihres Reichtums, ihrer Reitkunst und ihrer Weisheit bekannt gezeigt. Die Charakterisierung der Thessaler als gute Reiter findet sich in der antiken Literatur des Öfteren (vgl. u. a. Plat. Hipp. mai. 284a; Plat. leg. 625c-d.). Xen. Hell. 6,1,9-10 und Diod. 15,85,4-5 gelten sie zudem als talentierte Speerwerfer
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