5,300 research outputs found
METABOLOMIC PATTERNS OF PRETERM NEWBORNS WITH AND WITHOUT GROWTH RESTRICTION: MARKERS OF NUTRITIONAL AND CLINICAL STATUS
No full textBackground: the first thousand days of life are a critical period of time. The impact of growth restriction and nutritional issues in such early age could affect neurodevelopment and contribute to the onset of chronic adult diseases. This is especially true for preterm infants who experienced intrauterine growth restriction (IUGR) and for preterm infants who fail to thrive during the first weeks of life and develop extrauterine growth restriction (EUGR). These groups of premature babies are interesting populations to investigate with a metabolomic approach to optimize nutritional intakes.
Aims of the study: to identify clinical, biochemical and nutritional parameters associated with the IUGR condition and looking for risk factors related to extra-uterine growth retardation; to analyse and compare the urinary metabolomic pattern at birth of preterm infants with and without growth restriction at 36 weeks of postmenstrual age or at discharge, searching for potential predictive biomarkers of growth failure in the very low birth weight infants (VLBWI); to compare the urinary metabolomic profile at birth of preterm infants who develop retinopathy of prematurity (ROP, a disease related also to suboptimal nutrition) compared to preterm infants who do not develop it.
Materials and Methods: we enrolled preterm infants between 23 and 32 weeks of gestational age (GA) and/or with a birth weight <1500 g admitted to the Neonatal Intensive Care Unit (NICU) of the Department of Woman’s and Child’s Health of Padova University Hospital with early initiation of parenteral nutrition (PN). We collected clinical, biochemical and nutritional parameters from birth to 36 weeks of gestational age or discharge. Of a subgroup of patients with and without EUGR and with and without ROP we collected urinary samples within 48 hours of life and performed metabolomic analysis.
Results: from 354 newborns enrolled, 75 IUGRs were paired with 75 non-IUGRs. IUGR infants had lower anthropometric parameters at birth and during hospitalisation, they continued parenteral nutrition longer and reached full enteral feeding later. They showed reduced phosphoremia and almost all of them had EUGR at 36 weeks of GA or at discharge. We found as risk factors of EUGR also in general population lower phosphoremia levels, poor energy and protein intake, prolonged parenteral nutrition and a delay in achieving full enteral feeding. For the metabolomic analysis 16 EUGR infants were selected and matched with 16 controls: they showed a different urinary metabolomic profile at birth, characterised especially by lower levels of anti-inflammatory and anti-oxidant metabolites. Furthermore 6 ROP infants were selected and matched with 6 controls: we found a different urinary metabolomic profile with lower level of L-histidine and L-homoserine in the ROP group, suggesting a pro-inflammatory state and an altered synthesis of the sphingolipids.
Conclusions: growth restriction remains a serious problem in extremely preterm newborns, despite significant advancements in the nutritional care. EUGR is a complex and multifactorial condition but metabolomic analysis suggests a basal predisposition, which identification could be useful to tailor nutritional strategies. Similarly, ROP disease seems to be characterised by specific features in the metabolome at birth
Macronutrients and Micronutrients in Parenteral Nutrition
No full textAppropriate nutrition is of paramount importance during infancy and childhood, and Parenteral Nutrition (PN), which is the intravenous infusion of nutrients in the elementary form, may be necessary as a supplement or a full replacement for enteral nutrition [...
Stages for the More Sustainable Farm
No full textCurrently, agricultural farm units are faced with a double and most times contradictory challenge, in order to be successful: on the one hand the invested capital has to be profitable and the economic performance has to be maximised. On the other hand, given the socio-environmental situation, it is necessary to preserve and to protect the environment and natural resources. Given the potential conflict of the two aims, since the satisfaction of one implies the underperformance of the other (and vice versa), the question then is: which is the solution to choose? We intend, in this work, to formulate a farm plan with the purpose of reconciling the criteria of environmental sustainability with that of economic competitiveness. For this achievement we proceed to the comparative study of sustainability of different groups of farms identified in the study area (first evaluation cycle) through MESMIS (“Marco para la Evaluación de Sistemas de Manejo de Recursos Naturales Mediante Indicadores de Sustentabilidad” - Framework for Evaluation of Natural-Resource Systems Handling through Sustainability Indicators) methodology, that allowed to select the more sustainable group of farms. Based on the found potentialities and weakness on these production systems, we stepped to the planning of a production unit of bovine meat, which obeys simultaneously to economic and environmental objectives, using Multicriteria Decision. We finished the work with the sustainability evaluation between groups of farms identified previously and the planned farms (second evaluation cycle), based, again, in the MESMIS methodology, to confirm (or not) the greatest sustainability of the last ones. Analyses of the results allow us to confirm the greatest relative sustainability of the planned farm, for the diverse traced scenarios.Decision taking, planning, sustainability, Environmental Economics and Policy, Farm Management,
Parole d'artiste : Marta Cuscunà
No full textInternational audienceModeration of the interview with Marta Cuscunà, an Italian performer, director, puppeteer and author. In 2009, she was awarded the Premio Scenario per Ustica for E bello vivere liberi!, first show of a trilogy on female resistance, followed by La semplicità ingannata (2012) and Sorry, boys (2015). These three texts are published in Resistenze femminili (Udine: Forum, 2019). In 2018 she created Il canto della caduta. Earthbound (2021) is her last devised show, which brings in the themes of ecofeminism, taking cues from the theories of Donna Haraway and Bruno Latour. In 2021 she became associate artist at the Piccolo Teatro in Milan. In 2023, she is guest of honor at the 11th Biennale internationale des arts de la marionette in Paris. She was awarded the prizes Rete Critica (2017), Premio della Critica – ANCT (2018) and Premio Hystrio - Altre Muse (2019).Animation de la discussion avec Marta Cuscunà, performeuse, metteuse en scène, marionnettiste et autrice italienne. En 2009, elle a remporté le prix Premio Scenario per Ustica pour È bello vivere liberi !, premier spectacle d’une trilogie sur les résistances féminines, suivi par La semplicità ingannata (2012) et Sorry, boys (2015). Ces trois textes ont été réunis dans Resistenze femminili (Udine : Forum, 2019). En 2018, elle a créé Il canto della caduta. Son dernier spectacle, Earthbound (2021), traite de l’écoféminisme en s’inspirant des théories de Donna Haraway et de Bruno Latour. En 2021, elle devient artiste associée au Piccolo Teatro de Milan. En 2023, elle est invitée d’honneur à la Biennale Internationale des Arts de la Marionnette à Paris. Elle a obtenu les prix Premio Rete Critica (2017), Premio della Critica – ANCT (2018) et Premio Hystrio - Altre Muse (2019)
Proposal for the optional subject Business Protocol in the career Bachelor in Education Economy.
No full textLa presente investigación educativa está encaminada al mejoramiento cualitativo en las normas de cortesía y protocolo en las distintas actividades sociales de los estudiantes y profesores de la Facultad de Ciencias Económicas de la Universidad Central “Marta Abreu” de Las Villas y de la eficiencia en aspectos particulares, para afianzar la buena imagen constituye, para el autor del estudio, el punto de partida para crear la línea de investigación en la carrera de Licenciatura en Educación Economía y el Grupo de Trabajo Científico Estudiantil Protocolo Empresarial, con la participación de los estudiantes del tercer año y profesores de la carrera de Licenciatura en Educación Economía; las temáticas a desarrollar responden a las investigaciones del profesor líder Ms.C. José Miguel Garcia Aguiar; que se integra al Proyecto Asociado a Programa; Sistema de Educación Cubano Perspectiva en Desarrollo, que dirige desde CITMA el DrC. Poul Torres; siendo miembro activo en el proyecto “La Educación Ciudadana y la Educación Cívica en la Escuela Cubana Actual que dirige DrC. J. Gardenia Ruiz Rodríguez. Profesora Titular que imparte la docencia en la carrera de Marxismo –Leninismo e Historia en la Sede Pedagógica “Félix Varela”. La novedad científica de la investigación radica en la concepción pedagógica del programa de la asignatura optativa Protocolo Empresarial, el cual incluye de forma holística diferentes momentos de reflexión individual y colectiva, para la investigación, aplicación y creación, al modelar las normas de cortesía y protocolo, en el área laboral y el personal en el contexto de la esfera empresarial.The present educational research is aimed at qualitative improvement in the rules of courtesy and protocol in the different social activities of the students and professors of the Faculty of Economics of the Central University "Marta Abreu" of Las Villas and the efficiency in particular aspects , To consolidate the good image constitutes, for the author of the study, the starting point to create the line of research in the career of Bachelor of Education Economics and the Working Group Scientific Student Business Protocol, with the participation of students of the third Year and professors of the Bachelor of Education in Economics; The topics to be developed respond to the research of the leading teacher Ms.C. José Miguel Garcia Aguiar; Which is part of the Program Associated Project; Cuban Education System Perspective in Development, directed by CITMA DrC. Poul Torres; Being an active member in the project "Citizen Education and Civic Education in the Current Cuban School directed by DrC. J. Gardenia Ruiz Rodríguez. Full Professor who teaches in the career of Marxism - Leninism and History in the Pedagogical Headquarters "Felix Varela". The scientific novelty of the research lies in the pedagogical conception of the program of the optional Business Protocol, which holistically includes different moments of individual and collective reflection for research, application and creation, in modeling the rules of courtesy and protocol, In the area of labor and personnel in the context of the business sphere.
Palabras claves: Etiqueta; Protocolo; Diplomacia; Protocolo empresarial;
Protocolo como individuo; Protocolo con el cliente
Early Optimal Parenteral Nutrition During NICU Stay and Neurodevelopmental Outcomes in Very Preterm Infants: State of the Art
No full textBackground: Preterm infants (PIs) are more susceptible to neurodevelopmental
impairment compared with term newborns. Adequate postnatal growth has been associ
ated with improved neurocognitive outcomes; therefore, optimization of nutrition may
positively impact the neurodevelopment of PIs. Objective: This study focused on macro
nutrient parenteral nutrition (PN) intake during the Neonatal Intensive Care Unit stay
and their associations with neurodevelopmental outcomes in PIs in the first two years of
life. Methods: The Embase, MEDLINE, and Cochrane Library databases were searched
using the following subject headings and terms (MeSH): “premature infants”, “parenteral
nutrition”, “growth”, “brain”, “neurodevelopment”, and “central nervous system dis
eases.” All relevant papers’ reference lists were manually searched. PN and neurodevel
opment studies concerning the first two years of life were collected and analyzed. Results:
275 potential studies were retrieved, 64 were selected for full-text reading, and 22 were
included (12 randomized controlled trials). While glucose intakes should be immediately
provided and strictly monitored avoiding hyperglycemia, the long-term outcomes of ag
gressive PN caloric intakes are uncertain. Early amino acid (AA) supplementation is man
datory and improves short-term growth, though it is questionable whether increased AA
and better neurodevelopment are directly related. Lipid infusion should be initiated right
after birth, and further investigation will enable us to ascertain the potential impacts of
lipid emulsions, particularly fish oil, on PI neurodevelopment. Conclusions: An aggres
sive PN and its possible metabolic complication could not favor neurodevelopment; the
way forward could be a customized approach, depending on the patient’s clinical state
and tolerance. Long-term follow-up studies and the search for specific markers of toler
ance are warranted
Recursos tic para la promoción de salud mental positiva a estudiantes universitarios en tiempos de coronavirus
No full textEl presente proyecto tuvo como objetivo generar recursos audiovisuales basados en TIC para promover bienestar y salud mental positiva en estudiantes universitarios en tiempos de pandemia. Se creó una Estrategia de comunicación del conocimiento que consistió en generar recursos audiovisuales basados en TIC para promover bienestar y salud mental positiva en estudiantes universitarios en tiempos de pandemia, vinculada al proyecto INV 2371 ESTUDIO DE LAS PROPIEDADES PSICOMÉTRICAS DE LAS ESCALAS DE BIENESTAR DE DIENER EN POBLACIÓN COLOMBIANA cuya autora principal es la Dra. Marta Martín. Los tipos de recursos audiovisuales generados fueron infografías, podCaps, videos, y poster, en total fueron 10 recursos, con un resultado en general de 423 vistas, 240 like y 10 opiniones. Por los resultados de la encuesta de opinión se concluyó que las tic juegan un papel fundamental en la promoción de salud mental, puesto que la mayoría de los estudiantes encuestados les pareció bueno el material expuesto.The objective of this project was to generate audiovisual resources based on ICT to promote well-being and positive mental health in university students in times of pandemic. A Knowledge Communication Strategy was created that consisted of generating ICT-based audiovisual resources to promote well-being and positive mental health in university students in times of pandemic, linked to the INV 2371 project STUDY OF THE PSYCHOMETRIC PROPERTIES OF THE WELL-BEING SCALES OF DIENER IN COLOMBIAN POPULATION whose main author is Dr. Marta Martín. The types of audiovisual resources generated were infographics, podCaps, videos, and posters, in total there were 10 resources, with an overall result of 423 views, 240 likes and 10 opinions. Based on the results of the opinion survey, it was concluded that ict plays a fundamental role in promoting mental health, since most of the students surveyed found the exposed material to be good.Resumen. -- Abstrac. -- 1 Justificación. -- 2 Objetivo general. -- 3 Marco conceptual. -- 4 Estado del arte. -- 5 Metodología. -- 6 Resultados. -- 7 Análisis. -- 8 Resultados de la encuesta de opinión. -- 9 Conclusión. -- 10 Recomendaciones. -- 11 [email protected]
Marta Sanz, literary critic
No full textEl presente trabajo analiza el desempeño de Marta Sanz como crítica literaria en suplementos y revistas culturales. Para ello, se centra en las prácticas críticas desarrolladas por la autora en las reseñas que ha venido escribiendo en los últimos años para Babelia, suplemento del diario El País, y para la revista Mercurio, a fin de hallar aquellos elementos centrales que singularizan su criterio de valoración.This paper analyzes Marta Sanz’s performance as literary critic in supplements and literary magazines. Therefore, it will focus on the critical practices developed by the author in the reviews she has been writing in the last years for Babelia, cultural supplement of the newspaper El País, and for the magazine Mercurio, in order to find out the key elements that singularize her evaluation criteria.Dossier: Escrituras del cuerpo: Marta SanzFacultad de Humanidades y Ciencias de la Educació
- …
