102,523 research outputs found
Mobilizing Cities towards a Low Carbon Future: Tambourines, Carrots and Sticks
No full textIn the transition towards a decarbonized energy system, we need city authorities to lead by example as public actors, to govern the actions of the private urban actors as local policy makers, and to conceive and manage the implementation of an integrated approach as coordinators, which we introduce in this paper as three levels of city smartness. Local governments however have institutional disincentives to act, and if they do act, they are confronted with urban actors that are reluctant to follow. This paper analyzes how city pioneers in Europe have been able to overcome these disincentives thanks to a combination of local circumstances and interventions by higher levels of government. We categorize the state of the art instruments that have been used by higher levels of government into “tambourines”, “carrots”, and “sticks”, and reflect on how the state of the art could be improved.cities; climate change; governance
How to "catch" floating populations? Fixing space and time while researching migration
No full textMeeus B. How to "catch" floating populations? Fixing space and time while researching migration. COMCAD Arbeitspapiere - working papers, 85. Bielefeld: COMCAD - Center on Migration, Citizenship and Development; 2010
Implicit Auctioning on the Kontek Cable: Third Time Lucky?
No full textCross-border capacities in Europe are currently inefficiently used. Implicit auctioning is about eliminating these cross-border trade inefficiencies by internalizing the arbitrage into the auction procedures of the Power Exchanges that are organizing trade nationally. On the Kontek Cable, implicit auctioning has been implemented without price coordination between the involved Power Exchanges. This implementation, referred to as “volume or dome coupling” as opposed to “price coupling”, has been argued to be institutionally easier to implement. The Kontek Cable experimented with three different implicit auctioning implementations whose performance we analyze empirically in this paper. We find that the third implementation is significantly outperforming the previous two implementations, but in this third implementation stakeholders partly abandoned the volume coupling approach they initially believed to be a viable alternative to price coupling.electricity, transmission, congestion management, market coupling
Constraining the structure of the transition disk HD 135344B (SAO 206462) by simultaneous modeling of multiwavelength gas and dust observations
No full textContext. Constraining the gas and dust disk structure of transition disks, particularly in the inner dust cavity, is a crucial step toward understanding the link between them and planet formation. HD 135344B is an accreting (pre-)transition disk that displays the CO 4.7 μm emission extending tens of AU inside its 30 AU dust cavity. Aims. We constrain HD 135344B's disk structure from multi-instrument gas and dust observations. Methods. We used the dust radiative transfer code MCFOST and the thermochemical code ProDiMo to derive the disk structure from the simultaneous modeling of the spectral energy distribution (SED), VLT/CRIRES CO P(10) 4.75 μm, Herschel/PACS [OI] 63 μm, Spitzer/IRS, and JCMT 12CO J = 3-2 spectra, VLTI/PIONIER H-band visibilities, and constraints from (sub-)mm continuum interferometry and near-IR imaging. Results. We found a disk model able to describe the current gas and dust observations simultaneously. Peer reviewe
A BIOPSYCHOSOCIAL APPROACH TO PHENOTYPE KNEE OSTEOARTHRITIS PATIENTS AWAITING TOTAL KNEE ARTHROPLASTY: A CROSS-SECTIONAL STUDY
No full textBackground: Osteoarthritis (OA) is accompanied by an excessive formation of underlying bone caused by homeostatic alterations. It has been described that in OA joints there is an up-regulation of the WNT/β-catenine pathway driving to the differentiation of Mesenchymal Stromal Cells (MSCs) into osteocytes [1]. Glyp-icans 1-6 act as co-receptors of WNT pathway, improving interactions between molecules [2]. On the other hand, NOTUM plays a role as a negative regulator of the pathway preventing WNT binding to its receptors and favouring the soluble form of Glypicans [3]. All these evidences lead us to think about the importance of Glypicans 1-6 and NOTUM in the osteogenic differentiation of MSCs in OA disease. Objectives: To determine the differences at gene and protein levels of Glypicans 1-6 and NOTUM in MSCs between OA patients and controls at baseline and during induced in vitro osteogenic differentiation. Methods: Bone Marrow Mesenchymal Stromal Cells (BM-MSCs) from both, 8 OA patients and 8 healthy donors were isolated from BM samples. BM samples were obtained by joint replacement and traumatic fractures. BM-MSCs were cultured during 21 days with normal culture medium and with osteogenic inducing medium. Cells and supernatant were recovered at 1, 7, 14 and 21 days. Protein levels were determined by ELISA in cells supernatant. Extraction and purification of RNA from cells and cDNA synthesis were performed. Glypicans 1-6 and NOTUM gene-expression was analysed by qPCR and normalized with housekeeping genes β-actin and RNA18S. The data were calculated with the method of fold change (2-ΔΔCt). Statical analysis were performed with GraphPad Prism 8.0. For the detection of outliers, the ROUT method (Q=1%) was used. Data were analyzed using t-test. Results: The mRNA levels of cells with normal culture medium were up-regulated in GPC6 (t=7d; p=0,016) in OA patients. During osteogenic differentiation, was observed a statistically significant up-regulation in levels of OA patients vs controls of GPC2 (t=14d; p=0,034), GPC4 (t=14d, p=0,025; t=21d, p=0,017), GPC5 (t=14d, p=0,007), GPC6 (t=14d, p=0,013) and NOTUM (t=14d, p=0,009) and down-regulation of GPC3 (t=7d, p=0,034). In addition, protein levels of NOTUM were lower compared to the control group in OA BM-MSCs (t=1d, p=0,049) and in the differentiation to osteocytes (t=1d, p=0,049; t=7d, p=0,043; t=14d, p=0,016). GPC3 levels were higher OA patients in all the times and in the two conditions (p However not used for this study., Mira Meeus: None declare
Bibliographie Hilarion G. Petzold 1958 – 2009 mit Anhang als Einführung
No full textDieses Archiv enthält die Gesamtbibliographie der Werke des Autors nebst einiger Texte „Über H. G. Petzold“ im Schlussteil der Bibliographie sowie einen Anhang mit einer Einführung in die Architektur des Werkes in seinem wissenslogischen Aufbau als Ausarbeitung seines „Tree of Science Modells“ (2007).This archive contains the complete bibliography of the author and some texts about H. G. Petzold, moreover an epilogue with an introduction to the architecture of the works in its epistemological structure and composition and as an elaborations of Petzold’s „Tree of Science Modell (2007).https://www.fpi-publikation.de/polyloge/01-2009-petzold-h-g-gesamtbibliographie-h-g-petzold-1958-2009-updating-november2009/peerReviewedpublishedVersio
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Power Exchange Auction Trading Platform Design (Ontwerp van een veilingsysteem voor elektrische energiebeurzen).
No full textDeze studie analyseert de door elektrische energiebeurzen georganiseerde veilingen in Europa. Beurzen zijn instituties die de groothandel in elektrische energie vergemakkelijken. De meeste beurzen organiseren aparte veilingen een dag voordat de levering plaatsvindt voor elk uur van de volgende dag. Generatoren, grootverbruikers, leveranciers en handelaars optimaliseren hun portfolios via deze handelsplatformen.Initieel organiseerden de meeste beurzen in Europa handel binnen nationale grenzen. In toenemende mate worden ze ook betrokken bij het organiseren van grensoverschrijdende handel. De veranderende context impliceert nieuwe uitdagingen maar hernieuwt ook de discussie over hoe vroegere uitdagingen werden aangepakt.Dit werk geeft inzicht in de problemen waarmee beurzen te kampen hebben. Het veilingsysteem is gemodelleerd als een optimalisatieprobleem met beperkingen en alternatieve oplossingen worden onderzocht. In zijn rol als veilingmeester, ontvangt de beurs door marktpartijen geïntroduceerde orders en beslist dan welke orders te aanvaarden en aan welke prijzen de contracten worden afgerekend. Het nemen van deze beslissing is niet vanzelfsprekend door netwerkbeperkingen, order formaten (blokorders) en politieke beperkingen. De tekst is onderverdeeld in drie delen die respectievelijk deze themas bespreken.
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3346: Samuel G. Freedman, author, 2013
No full textPhotograph of author Samuel G. Freedman, at NT Daily Slash meeting in the Mayborn School of Journalism at UNT
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