4,910 research outputs found

    Biography of Ceerno Ndiaye Ba

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    This manuscript is a biography of Ceerno Ndiaye Ba Bababe, in Mauritania. It is one of a series of biographies that the author has written about Islamic leaders in West Africa.Ce manuscrit est une biographie de Ceerno Ndiaye Ba Bababe, en Mauritanie. Elle fait partie d'une série de biographies que l'auteur a écrites sur les dirigeants islamiques en Afrique de l'Ouest

    Poems of Sheikh Muhammad al-Ghaly Ba

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    This volume contains seven poems handwritten by Muhammad al-Ghāli Ba. According to the author's son, Mountaga Ba, the poems were probably composed in the mid-1970s a time when the author lived in Mauritania, while working at the country's national radio station and serving as a special counsel to then president Moktar Ould Daddah (1924–2003). The poems adress various issues. The first is a call to action addressed to the Mauritianian youth, urging them to join in the collective work for the development of the country. The second poem is a hagiography on Ceerno Ahmad Nene Ba of Kaedi (Mauritania). The poem eulogizes the virtues of the patron. The third describes the event of Sharif Muhammad al-Habib's visit to the region of Fuuta region (Senegal), namely the village of Pate Galo. The fourth poem contains greetings and expresions of love addressed to the author's friends in the town of Kaedi. The fifth poem is a remembrance about good times. The author reminisces and praises the qualities of a woman named Jaari.The sixth poem describes one afternoon journey of the author. The seventh poem is a mournful praisesong in which the author laments the loss of a cherished person.Ce volume contient sept poèmes manuscrits de Muhammad al-Ghāli Ba. Selon le fils de l'auteur, Mountaga Ba, les poèmes ont probablement été composés au milieu des années 1970, à une époque où l'auteur vivait en Mauritanie, alors qu'il travaillait à la radio nationale du pays et était conseiller spécial du président de l'époque, Moktar Ould Daddah (1924). –2003). Les poèmes abordent diverses questions. Le premier est un appel à l'action adressé aux jeunes mauriciens, les exhortant à s'associer au travail collectif pour le développement du pays. Le deuxième poème est une hagiographie sur Ceerno Ahmad Nene Ba de Kaedi (Mauritanie). Le poème fait l'éloge des vertus du mécène. Le troisième décrit l'événement de la visite de Sharif Muhammad al-Habib dans la région de la région de Fuuta (Sénégal), à savoir le village de Pate Galo. Le quatrième poème contient des salutations et des expressions d'amour adressées aux amis de l'auteur dans la ville de Kaedi. Le cinquième poème est un souvenir des bons moments. L'auteur rappelle et loue les qualités d'une femme nommée Jaari. Le sixième poème décrit un après-midi de voyage de l'auteur. Le septième poème est une louange mélancolique dans laquelle l'auteur déplore la perte d'une personne chérie

    Coralline algal Barium as indicator for 20th century northwestern North Atlantic surface ocean freshwater variability

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    During the past decades climate and freshwater dynamics in the northwestern North Atlantic have undergone major changes. Large-scale freshening episodes, related to polar freshwater pulses, have had a strong influence on ocean variability in this climatically important region. However, little is known about variability before 1950, mainly due to the lack of long-term high-resolution marine proxy archives. Here we present the first multidecadal-length records of annually resolved Ba/Ca variations from Northwest Atlantic coralline algae. We observe positive relationships between algal Ba/Ca ratios from two Newfoundland sites and salinity observations back to 1950. Both records capture episodical multi-year freshening events during the 20th century. Variability in algal Ba/Ca is sensitive to freshwater-induced changes in upper ocean stratification, which affect the transport of cold, Ba-enriched deep waters onto the shelf (highly stratified equals less Ba/Ca). Algal Ba/Ca ratios therefore may serve as a new resource for reconstructing past surface ocean freshwater changes

    Longitudinal analysis of serum neutralization of SARS-CoV-2 Omicron BA.2, BA.4, and BA.5 in patients receiving monoclonal antibodies

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    The emergence of Omicron sublineages impacts the therapeutic efficacy of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) monoclonal antibodies (mAbs). Here, we evaluate neutralization and antibody-dependent cellular cytotoxicity (ADCC) activities of 6 therapeutic mAbs against Delta, BA.2, BA.4, and BA.5. The Omicron subvariants escape most antibodies but remain sensitive to bebtelovimab and cilgavimab. Consistent with their shared spike sequence, BA.4 and BA.5 display identical neutralization profiles. Sotrovimab is the most efficient at eliciting ADCC. We also analyze 121 sera from 40 immunocompromised individuals up to 6 months after infusion of Ronapreve (imdevimab + casirivimab) or Evusheld (cilgavimab + tixagevimab). Sera from Ronapreve-treated individuals do not neutralize Omicron subvariants. Evusheld-treated individuals neutralize BA.2 and BA.5, but titers are reduced. A longitudinal evaluation of sera from Evusheld-treated patients reveals a slow decay of mAb levels and neutralization, which is faster against BA.5. Our data shed light on antiviral activities of therapeutic mAbs and the duration of effectiveness of Evusheld pre-exposure prophylaxis

    Boundary Algebra: A Simpler Approach to Boolean Algebra and the Sentential Connectives

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    Boundary algebra [BA] is a algebra of type , and a simplified notation for Spencer-Brown’s (1969) primary algebra. The syntax of the primary arithmetic [PA] consists of two atoms, () and the blank page, concatenation, and enclosure between ‘(‘ and ‘)’, denoting the primitive notion of distinction. Inserting letters denoting, indifferently, the presence or absence of () into a PA formula yields a BA formula. The BA axioms are A1: ()()= (), and A2: “(()) [abbreviated ‘⊥’] may be written or erased at will,” implying (⊥)=(). The repeated application of A1 and A2 simplifies any PA formula to either () or ⊥. The basis for BA is B1: abc=bca (concatenation commutes & associates); B2, ⊥a=a (BA has a lower bound, ⊥); B3, (a)a=() (BA is a complemented lattice); and B4, (ba)a=(b)a (implies that BA is a distributive lattice). BA has two intended models: (1) the Boolean algebra 2 with base set B={(),⊥}, such that () ⇔ 1 [dually 0], (a) ⇔ a′, and ab ⇔ a∪b [a∩b]; and (2) sentential logic, such that () ⇔ true [false], (a) ⇔ ~a, and ab ⇔ a∨b [a∧b]. BA is a self-dual notation, facilitates a calculational style of proof, and simplifies clausal reasoning and Quine’s truth value analysis. BA resembles C.S. Peirce’s graphical logic, the symbolic logics of Leibniz and W.E. Johnson, the 2 notation of Byrne (1946), and the Boolean term schemata of Quine (1982).Boundary algebra; boundary logic; primary algebra; primary arithmetic; Boolean algebra; calculation proof; G. Spencer-Brown; C.S. Peirce; existential graphs

    Monitoring of the SARS-CoV-2 Omicron BA.1/BA.2 lineage transition in the Swedish population reveals increased viral RNA levels in BA.2 cases

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    BACKGROUND: Throughout the SARS-CoV-2 pandemic, multiple waves of variants of concern have swept across populations, leading to a chain of new and yet more contagious variants dominating COVID-19 cases. Here, we tracked the remarkably rapid shift from Omicron BA.1 to BA.2 sublineage dominance in the Swedish population in early 2022 at a day-by-day basis. METHODS: Using a custom SARS-CoV-2 Omicron BA.1 lineage-typing RT-PCR assay, we analyzed 174,933 clinical upper airway samples collected during January to March 2022. FINDINGS: Our study demonstrates the feasibility and reliability of parallel lineage assignment of select variants at population scale, tracking the dominant sublineage transition from BA.1 to BA.2 at day-to-day resolution and uncovering nearly 2-fold higher levels of viral RNA in cases infected with Omicron BA.2 relative to BA.1. CONCLUSIONS: Our data provide unique insights into the Omicron BA.1 to BA.2 transition that occurred in Sweden during early 2022, and later, across the world. This may help to understand the increased transmissibility of the BA.2 variant
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