1,720,983 research outputs found
May a Single Presurgical High-Field MRI Sequence Replace Standard Radiographs for TPLO Surgical Planning in Dogs?
No full text: Cranial cruciate ligament (CCL) disease causes variable stifle instability assessed by specific clinical tests. Radiographs are performed to measure the tibial plateau angle (TPA) for planning tibial plateau leveling osteotomy (TPLO) surgery. Concomitant damage to other intra-articular structures, for which clinical detection is unreliable, may occur and potentially affect the surgical outcome. Joint assessment during TPLO through instrumented inspection is therefore advised, though it increases the risk of complications. Magnetic resonance imaging offers a noninvasive alternative, adds information about intra- and periarticular structures, and could potentially be used for TPA measurements. This prospective study aimed to (1) assess the correlation between the TPA measured with the standard presurgical radiographs and with a single sagittal intermediate-weighted fat-saturated MRI sequence and (2) compare the surgical findings with the information obtained by the MRI sequence. Twenty-one stifles were included; TPA correlation using radiographs-MRI was available for 17 stifles, and surgery-MRI comparison was available for 18 stifles. A strong significant correlation was identified between the TPA measurements on radiographs-MRI (Pearson correlation coefficient 0.923; p-value <.0001). The sensitivity and specificity of MRI to detect surgically confirmed complete versus partial CCL rupture were 85.7% and 75%, respectively; MRI identified 7 of 8 surgically confirmed injured menisci and detected abnormal signal intensity in 8 of 10 medial menisci and nine caudal cruciate ligaments reported as normal intra-operatively. The MRI additionally identified abnormal subchondral bone signals in nine stifles and muscular hyperintensity in six cases. This presurgical MRI sequence might replace standard radiographs for TPA measurements and can provide information about concomitant joint injuries with potential prognostic impact
Indagini archeologiche presso il tempio forense di Cupra Marittima (AP)
Full text linkThe University of Naples L'Orientale, after a long pause in its investigations in the area of the Forum of Cupra, hasstarted a new research project aimed at understanding the occupation phases of the city's monumental area and the topographical development of the entire settlement area. Research in the forensic area, after the first investigations in the eighteenth and nineteenth centuries, in which the focus was mainly on the recovery of objects, had received an initial impulse in the second half of the twentieth century, by the competent Superintendency, followed by the large-scale excavation and valorisation project by Arcus spa. Despite the great economic effort put into the field investigations, and the valorisation of the archaeological park with the creation of reception facilities, the vast amount of data collected in those investigations remained unpublished, with the exception of a preliminary edition.
L’Università di Napoli L’Orientale, dopo una lunga sosta nelle indagini nell’area del Foro di Cupra, ha
avviato un nuovo progetto di ricerca volto a comprendere le fasi di occupazione dell’area monumentale cittadina e lo sviluppo topografico dell’intera area dell’abitato. Le ricerche nell’area forense, dopo le prime indagini del Settecento e Ottocento, in cui l’interesse era soprattutto il recupero di oggetti , avevano avuto un primo impulso nella seconda metà del Novecento, ad opera della competente Soprintendenza, seguito dal grande progetto di scavo e valorizzazione ad opera della Arcus spa. Nonostante il grande impegno economico profuso nelle indagini sul campo, e nella valorizzazione del parco archeologico con la creazione di strutture di accoglienza, di fatto la gran quantità di dati raccolti in quelle ricerche sono rimasti inediti, ad eccezione di una preliminare edizione
Clinical and MRI features of hemorrhagic transformation of an ischemic stroke in a dog
No full textHemorrhagic transformation (HT) is a well described complication of ischemic stroke in humans, associated with increased morbidity and mortality, secondary to blood-brain barrier disruption and reperfusion. Aim of this case report is to describe the MRI features of a clinically suspected HT after ischemic stroke in a dog.
An eight-year-old female neutered mixed-breed dog presented with acute onset of intracranial clinical signs consistent with a left-sided forebrain disease.
MRI, performed within 12 hours from the onset of clinical signs, revealed a large well-defined area of high diffusion-weighted imaging (DWI) signal and corresponding low apparent diffusion coefficient (ADC) map values, indicative of abnormal restricted diffusion, encompassing the majority of the vascular territory supplied by the left middle cerebral artery. The lesion was not visible in any other sequence, suggesting a peracute ischemic infarct. Cerebrospinal fluid examination was unremarkable. Concurrent medical conditions associated with the cerebrovascular accident were not identified.
In the following 24 hours the dog showed severe clinical deterioration, suggesting a brainstem involvement. A 40-hour follow-up MRI revealed mixed T2-weighted hyper- and hypointense areas in the same vascular territory, different combinations of DWI signal and ADC map values, and a severe mass effect. Extensive susceptibility artifacts in Flow Sensitive Black Blood imaging were detected, indicating HT of the previous ischemic infarct. Discussion
HT may represent a sequela of ischemic infarcts in dogs as described in humans. Rapid and severe clinical deterioration in a patient previously diagnosed with ischemic stroke should raise suspicion and warrant further MRI evaluation
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Aripiprazole augmentation in poor insight obsessive-compulsive disorder: a case report
Full text linkAbstract Background Obsessive-compulsive disorder is associated with a relevant impairment in social and interpersonal functioning and severe disability. This seems to be particularly true for the poor insight subtype, characterised by a lack of consciousness of illness and, consequently, compliance with treatment. Poor responsiveness to serotonergic drugs in poor insight obsessive-compulsive patients may also require an augmentation therapy with atypical antipsychotics. Methods We reviewed a case in which a patient with a long history of poor insight obsessive-compulsive disorder was treated with a high dosage of serotonin reuptake inhibitors. Results The treatment resulted in a poor outcome. This patient was therefore augmentated with aripiprazole. Conclusion Doctors should consider aripiprazole as a possible augmentation strategy for serotonergic poor responder obsessive-compulsive patients, but further research on these subjects is needed.</p
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