3,524 research outputs found
'Beyond, both the Old World, and the New': Authority and Knowledge in the works of Francis Bacon, with special reference to the New Atlantis
No full textPhDThis study investigates the role of authority in the works of Francis Bacon,
arguing that the issue of authority provides not only an interpretation of New
Atlantis, but an important structural component of his body of works. From
the first manifestation of his philosophical project to his last works of natural
history, authority is an all-pervasive issue - the authority of nature, of
scripture, of the named author, and how authority functions in the
dissemination of natural knowledge. Chapter one argues that the publication
of New Atlantis alongside Sylva sylvarum in 1626/7 was more the result of
William Rawley's need to assert his own authority as the protector and
disseminator of Bacon's textual legacy than an appreciation of the work's own
qualities. Chapter two considers Bacon's views of history and time,
suggesting that Bacon not only conceived of a new, progressive mode of
historical time which would allow for the assertion of a textual authority based
on the records of a civilisation unbroken by the vicissitudes of time, but that
he figured these theories in New Atlantis. Chapter three argues that Bacon
used theology both as defence and imperative to his intellectual programme,
while his attempt to move beyond the deterministic, Calvinist world-view to
allow for multiple possible futures, or `chance': Bacon could then present
experiment as the way of eliminating chance, in order to accelerate the rate of
new discovery. Chapter four investigates Bacon's manipulations of textual
authority, from the early rehearsals of the Instauratio magna to the
performance of reliability in print in Sylva sylvarum. Finally, the afterword
seeks to suggest that the New Atlantis hinges on the issues of authority with
which Bacon engaged throughout his career and writings: in the issue of
authority, Francis Bacon found the beginning and the end of his philosophy
NK cells beat T cells at early breast cancer control
No full textCancer immunosurveillance generally relies on adaptive immune programs executed by CD8+ T cells. Our findings demonstrate that CD8+ T cells fail to control early oncogenesis in a mouse model of luminal B breast cancer and suggest that natural killer (NK) cells may instead play a predominant role in this setting. © 2020 The Author(s). Published with license by Taylor & Francis Group, LLC
''Menger Hotel,'' San Antonio, Texas
No full textThis view of the famous Menger Hotel in San Antonio was taken by A. F. Dignowity, the son of author, daguerreotypist, and physician Anthony Michael Dignowity. Dignowity operated for a relatively short period of time, and his work is uncommon. Source: Lawrence T. Jones III.Attributed to: Dignowity, A. F. (Anthony Francis), 1844-1921. Verso: [handwritten in ink] ''Menger Hotel'' San Antonio Texas
Redemption in the work of Francis Stuart
No full textThe idea of redemption is central to an understanding of the work
of Francis Stuart. Through an examination of its development and
expression, it is possible to demonstrate the integrity of his work and
its distinctive qualities. Such a demonstration is necessary because
Stuart's writing has been subjected to comparatively little scholarly
inquiry, although reviews of his work, especially that produced since
1949, suggest that it is impressive and important.
First, a general background to Stuart's work, a discussion of the
special problems associated with reading it, and a summary of his corpus
is provided. This indicates that the idea of redemption is important to
his earliest writing. The state of redemption is shown to be a
necessary apotheosis for Stuart's outcast heroes; it involves spiritual
suffering through which may be found a sense of reintegration and a
higher reality. This is expressed through interrelated themes such as
those of gambler, artist and ordinary man; mystic and criminal; sacred
and profane love; and spirituality and the mundane. The nature of the
redemptive experience is further elaborated by distinctive, complex
motifs, especially the hare, the ark and the woman-Christ. Their
recurrence provides an important element in the unity of Stuart's work.
Because Stuart's idea of the outcast raises important biographical
questions, an examination of the relationship between Stuart's life and
his work is made. Finally, the way in which the idea of redemption
exists in the language structures of Stuart's novels is examined, with
especial reference to his most recent work, The High Consistory. The
thesis shows that the development of the these of redemption
demonstrates the integrity of Stuart's work
Poems of the late Francis S. Key : esq., author of "The Star Spangled Banner" ; with an introductory letter by Chief Justice Taney.
No full textFirst edition. BAL 11093.; Edited by Henry V.D. Johns.; BAL binding C: except red T cloth; stamped in gold all edges gilt; yellow endpapers
Analysis of the effects of cost cutting measures on financial performance: a case of ZETDC
No full textThe purpose of this research was to investigate the effects of cost cutting measure on financial performance using ZETDC as a case. The research objectives outlined the nature of cost cutting techniques, how cost cutting affect financial performance and challenges faced in the implementation of cost cutting. The descriptive survey research design was used and data was gathered through the use of structured questionnaires and interviews and a total population of 41 employees which included the top management, Accountants, HR and internal auditors was sampled using convenience and purposive sampling. A case study
approach was undertaken using both qualitative and quantitative data hence the study is therefore a mixed design approach. The research was designed in a way that allows both field research and secondary sources to be used. Research instruments considered for the purposes of this research are questionnaires which had 88% response rate and interviews which yielded 100% response rate. The data gathered was presented through histograms, bar graphs, pie charts and tables. The data accumulated was analysed using descriptive statistics specifically percentages and mode and rational conclusions were drawn from this. Upon data analysis, it was revealed that ZETDC cost cutting measures positively affects the financial performance in the long run but in the short run the financial woes will worsen before they improve. The recommendations passed by the researcher included the improvement of current cost cutting measures and continuation with the application of the cost cutting measures. The researcher
also recommended ZETDC to implement controls so as to make sure that all current cost control procedures and policies are adhered to, budget formulation and introduction of incentives and bonuses for meeting budgets and lastly renegotiating existing transfer prices in contracts agreed with other subsidiaries of ZESA
Muted Voices of the New Testament:Readings in the Catholic Epistles and Hebrews
No full textPauline- and Gospel-centred readings have too long provided the normative understanding of Christian identity. The chapters in this volume features evidence from other, less-frequently studied texts, so as to broaden perspectives on early Christian identity. Each chapter in the collection focuses on one or more of the later New Testament epistles and answers one of the following questions: what did/do these texts uniquely contribute to Christian identity? How does the author frame or shape identity? What are the potential results of the identities constructed in these texts for early Christian communities? What are the influences of these texts on later Christian identity?Together these chapters contribute fresh insights through innovative research, furthering the discussion on the theological and historical importance of these texts within the canon. The distinguished list of contributors includes: Richard Bauckham, David G. Horrell, Francis Watson, and Robert W. Wall
Repurposing CD8 + T cell immunity against SARS-CoV-2 for cancer immunotherapy: a positive aspect of the COVID-19 pandemic?
No full textThe COVID-19 pandemic has afflicted most countries on the planet. As a result, immunity against SARS-CoV-2, induced via natural infections or imminent vaccinations, is expected to develop in a large fraction of the global population. Here, we propose to exploit SARS-CoV-2-specific CD8[+] T cells for cancer immunotherapy strategies. © 2020 The Author(s). Published with license by Taylor & Francis Group, LLC
Of the Helmholtz Club, South-Californian seedbed for visual and cognitive neuroscience, and its patron Francis Crick
No full textTaking up the view that semi-institutional gatherings such as clubs, societies, research schools, have been instrumental in creating sheltered spaces from which many a 20th-century project-driven interdisciplinary research programme could develop and become established within the institutions of science, the paper explores the history of one such gathering from its inception in the early 1980s into the 2000s, the Helmholtz Club, which brought together scientists from such various research fields as neuroanatomy, neurophysiology, psychophysics, computer science and engineering, who all had an interest in the study of the visual system and of higher cognitive functions relying on visual perception such as visual consciousness. It argues that British molecular biologist turned South Californian neuroscientist Francis Crick had an early and lasting influence over the Helmholtz Club of which he was a founding pillar, and that from its inception, the club served as a constitutive element in his long-term plans for a neuroscience of vision and of cognition. Further, it argues that in this role, the Helmholtz Club served many purposes, the primary of which was to be a social forum for interdisciplinary discussion, where ‘discussion’ was not mere talk but was imbued with an epistemic value and as such, carefully cultivated. Finally, it questions what counts as ‘doing science’ and in turn, definitions of success and failure—and provides some material evidence towards re-appraising the successfulness of Crick’s contribution to the neurosciences
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