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The serrated neoplasia pathway: investigating the role of serrated polyps in colorectal cancer development
Get PDFDikkedarmkanker kan zich op verschillende manieren ontwikkelen. Eerder is aangetoond dat bepaalde dikke darmpoliepen, adenomen genaamd, zich tot dikkedarmkanker kunnen ontwikkelen. ‘Serrated’ poliepen zijn poliepen die van oudsher als goedaardige poliepen werden beschouwd. Patiënten met hyperplastische polyposis syndroom (HPS) hebben veel van deze ‘goedaardige’ serrated poliepen in hun dikke darm. Karaim Singh Boparai toont aan dat HPS patiënten en hun familieleden vaak dikkedarmkanker hebben en dat deze dikkedarmkankers voornamelijk ontstaan uit serrated poliepen. In tegenstelling tot wat eerder werd verondersteld, lijken serrated poliepen dus niet uitsluitend goedaardig te zijn. Endoscopisch onderzoek met nieuwe endoscopische technieken, zoals ‘narrow-band imaging’, en verwijdering van deze poliepen is klinisch relevant om dikkedarmkanker te voorkomen
UvA-DARE (Digital Academic Repository) Open Access Daily enteral feeding practice on the ICU: attainment of goals and interfering factors
No full textDaily enteral feeding practice on the ICU: attainment of goals and interfering factors Binnekade, J.M.; Tepaske, R.; Bruynzeel, P.; Mathus-Vliegen, E.M.H.; de Haan, R.J. Disclaimer/Complaints regulations If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: https://uba.uva.nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible. Abstract Background The purpose of this study was to evaluate the daily feeding practice of enterally fed patients in an intensive care unit (ICU) and to study the impact of preset factors in reaching predefined optimal nutritional goals
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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