2,128 research outputs found
[Podcast] A l'écoute des Japon(s) - La "Nouvelle Vague" japonaise : entretien avec Mathieu Capel
No full textPour ce troisième épisode d’À l’écoute des Japon(s), nous recevons Mathieu Capel, maître de conférences en études cinématographiques à l’université de Tokyo et chercheur associé au Centre de recherches sur le Japon de l'EHESS. Nous abordons notamment ses travaux sur la « Nouvelle Vague japonaise » du cinéma des années 1950-70, mais également son parcours de chercheur, et la place particulière qu’il accorde à la traduction dans son travail. Podcast réalisé et produit par Valentin Dubanet, étud..
Treatment of adult-onset Still’s disease: a review
No full textYvan Jamilloux,1–3,* Mathieu Gerfaud-Valentin,1,* Thomas Henry,3 Pascal Sève1 1Department of Internal Medicine, Hôpital de la Croix-Rousse, Université Claude Bernard-Lyon 1, Lyon, France; 2Department of Biochemistry, University of Lausanne, Epalinges, Switzerland; 3International Research Center on Infectiology. INSERM U1111. Université Claude Bernard-Lyon 1, Lyon, France *These authors contributed equally to this work Abstract: Adult-onset Still’s disease (AOSD) is a rare inflammatory disorder that has been recently classified as a polygenic autoinflammatory disorder. The former classification, based on the disease course, seems to be quite dated. Indeed, there is accumulating evidence that AOSD can be divided into two distinct phenotypes based on cytokine profile, clinical presentation, and outcome, ie, a “systemic” pattern and an “articular” pattern. The first part of this review deals with the treatments that are currently available for AOSD. We then present the different strategies based on the characteristics of the disease according to clinical presentation. To do so, we focus on the two subsets of the disease. Finally, we discuss the management of life-threatening complications of AOSD, along with the therapeutic options during pregnancy. Keywords: adult-onset Still’s disease, treatment, anakinra, tocilizumab, canakinuma
Arabic and English Spatial Entity Dataset for Animal Disease Surveillance Extracted with PADI-web
No full textAs part of the “Arabic Corpus and Entities Dealing with Animal Disease Surveillance Extracted with PADI-web” dataset (https://doi.org/10.18167/DVN1/2B4WLR), we built a new dataset containing 284 spatial entities in Arabic, their translation into English (manually validated) and their automatic translation by three automatic tools (DeepL, Microsoft Azure, and Reverso). The dataset was updated with two new columns on September 3, 2025: GeoNames ID and GeoNames Feature Class, enabling the matching of spatial entities to the GeoNames gazetteer.
The dataset is organised as a table with twelve columns :
ID: The unique identifier of each article (from PADI-web database)
Arabic Location: The spatial entities in Arabic, manually extracted from 53 articles collected via PADI-web
English Location: The manual translation of spatial entities into English, based on existing field sources such as Google Maps and the GeoNames database
GeoNames ID: The unique ID from the GeoNames database (2022 version of GeoNames: https://www.geonames.org/) corresponding to each spatial entity (empty if no match in GeoNames)
GeoNames Feature Class : The feature class corresponding to the GeoNames ID (empty if no match in GeoNames)
Type: A manually assigned type of spatial entity (country, city, region, village, etc.).
Category: The classification of spatial entities into two categories: absolute spatial entities (ASE) and relative spatial entities (RSE).
Arabic Phrases: The sentence, in Arabic, from which the spatial entity was extracted.
Translation DeepL: The translation of the location by DeepL.
Translation Microsoft Azure: The translation of the location by Microsoft Azure.
Translation Reverso: The translation of the location by Reverso.
English Sentences Translated by DeepL: The translation of the sentence by DeepL.
English Sentences Translated by Microsoft Azure: The translation of the sentence by Microsoft Azure.
English Sentences Translated by Reverso: The translation of the sentence by Reverso.
Absolute spatial entities are direct references to precise, locatable geographic spaces, i.e. entities that can be located on a map or in a geographic database (e.g. cities such as Safi, countries such as Morocco, Egypt, etc.).
Relative spatial entities are entities defined in relation to at least one other spatial entity, using spatial indicators of a topological nature (for example, “الطود شرق” (El-Tod East), “ناحية تلات” (Talat district), etc.)
Refractory Sarcoidosis: A Review
No full textThomas El Jammal,1 Yvan Jamilloux,1 Mathieu Gerfaud-Valentin,1 Dominique Valeyre,2 Pascal Sève1,3 1Department of Internal Medicine, Lyon University Hospital, Lyon, France; 2Department of Pneumology, Assistance Publique - Hôpitaux de Paris, Hôpital Avicenne et Université Paris 13, Sorbonne Paris Cité, Bobigny, France; 3Hospices Civils de Lyon, Pôle IMER, Lyon, F-69003, France, University Claude Bernard Lyon 1, HESPER EA 7425, Lyon F-69008, FranceCorrespondence: Pascal SèveService de Médecine Interne, Groupement Hospitalier Nord, 103 Grande rue de la Croix-Rousse, Lyon F-69004, FranceTel +33 426 732 636Fax +33 426 732 637Email [email protected]: Sarcoidosis is a multi-system disease of unknown etiology characterized by granuloma formation in various organs (especially lung and mediastinohilar lymph nodes). In more than half of patients, the disease resolves spontaneously. When indicated, it usually responds to corticosteroids, the first-line treatment, but some patients may not respond or tolerate them. An absence of treatment response is rare and urges for verifying the absence of a diagnosis error, the good adherence of the treatment, the presence of active lesions susceptible to respond since fibrotic lesions are irreversible. That is when second-line treatments, immunosuppressants (methotrexate, leflunomide, azathioprine, mycophenolate mofetil, hydroxychloroquine), should be considered. Methotrexate is the only first-line immunosuppressant validated by a randomized controlled trial. Refractory sarcoidosis is not yet a well-defined condition, but it remains a real challenge for the physicians. Herein, we considered refractory sarcoidosis as a disease in which second-line treatments are not sufficient to achieve satisfying disease control or satisfying corticosteroids tapering. Tumor necrosis alpha inhibitors, third-line treatments, have been validated through randomized controlled trials. There are currently no guidelines or recommendations regarding refractory sarcoidosis. Moreover, criteria defining non-response to treatment need to be clearly specified. The delay to achieve response to organ involvement and drugs also should be defined. In the past ten years, the efficacy of several immunosuppressants beforehand used in other autoimmune or inflammatory diseases was reported in refractory cases series. Among them, anti-CD20 antibodies (rituximab), repository corticotrophin injection, and anti-JAK therapy anti-interleukin-6 receptor monoclonal antibody (tocilizumab) were the main reported. Unfortunately, no clinical trial is available to validate their use in the case of sarcoidosis. Currently, other immunosuppressants such as JAK inhibitors are on trial to assess their efficacy in sarcoidosis. In this review, we propose to summarize the state of the art regarding the use of immunosuppressants and their management in the case of refractory or multidrug-resistant sarcoidosis.Keywords: refractory sarcoidosis, JAK inhibitors, anti-TN
Missa cum quinque vocibus, ad imitationem moduli Vidi speciosam, condita . Nunc primùm in lucem edita. Autore D. Mathaeo Sohier,...
No full textTitre uniforme : Sohier, Mathieu (15..-1560?). Compositeur. [Missa Vidi speciosam]Présentation musicale : [Livre de choeur]Appartient à l’ensemble documentaire : RISMImpMesses (musique) -- +* 1500......- 1599......+:16e siècle
Missa cum quinque vocibus, ad imitationem moduli Vidi speciosam, condita . Nunc primùm in lucem edita. Autore D. Mathaeo Sohier,...
No full textTitre uniforme : Sohier, Mathieu (15..-1560?). Compositeur. [Missa Vidi speciosam]Présentation musicale : [Livre de choeur]Appartient à l’ensemble documentaire : RISMImpMesses (musique) -- +* 1500......- 1599......+:16e siècle
Maladie de Still de l'adulte (manifestations, traitements, évolution et facteurs pronostiques chez 57 patients)
No full textLe but de cette étude observationnelle rétrospective est de décrire une cohorte française de maladies de Still de l'adulte (MSA) et d'en identifier les facteurs pronostiques. Les patients devaient remplir les critères de classification de Yamaguchi ou Fautrel à l'inclusion. Les variables candidates ont été analysées en régression multivariée non ajusté puis ajusté sur les variables potentiellement confondantes. Cinquante-sept patients sont suivis en moyenne 8,4 ans en médecine interne (75%) ou rhumatologie (25%). Le délai diagnostic médian est de 4 mois. L'évolution est monocyclique chez 17 patients, intermittente chez 25 et chronique chez 15. Le dosage de la ferritine glycosylée (FG) réalisé chez 37 patients est corrélé à un diagnostic plus précoce. Neuf 18FDG-PET scanners montrent un hypermétabolisme des tissus lymphatiques et glandulaires. Les complications, dont le syndrome d'activation lymphohistiocytaire (n=8), sont fréquentes (n=19). Aucun des trois décès répertoriés n'est attribuable à la MSA. La corticodépendance, prédite par une FG basse, concerne 23 patients (45%). Un quart des patients a reçu des anti-TNFa ou de l'anakinra, bien tolérés. La fièvre > 39,5C est prédictive d'une évolution monocyclique de la MSA alors que les arthrites et la thrombopénie sont respectivement associées à une évolution chronique et compliquée de la maladie. Les patients les plus jeunes sont les plus à risque de résistance aux premières lignes de traitement. La MSA reste de diagnostic difficile, sa mortalité est faible malgré des complications fréquentes. La FG et le 18FDG-PET scanner sont utiles pour le diagnostic. Les patients initialement très symptomatiques évolueront vers une forme systémique de MSA alors que ceux présentant seulement des arthrites évolueront vers une forme articulaire chronique.LYON1-BU Santé (693882101) / SudocSudocFranceF
Alf Nilsen-Børsskog — The Author Chosen by the Language
No full textThis article discusses Alf Nilsen-Børsskog’s four-volume series of novels Elämän jatko [Continuation of life, 2004–2015], seen as the first literary works treating the Kven culture from a native perspective. Nilsen-Børsskog’s novels are analysed as constituting a “counterstory”, a term coined in the postcolonial cultural research paradigm to refer to self-representation. The Kvens have been considered a national minority in Norway since 1999, and their language has been an official minority language since 2005. The present author scrutinizes how Nilsen-Børsskog’s work differs from previous literary descriptions of this minority, often marked by the frequent use of stereotypes of the Kven language and culture
Guy de Maupassant : Valentin (Mathieu), À travers les Contes et Nouvelles de Guy de Maupassant, image de la pharmacie et des pharmaciens au XIXe siècle. Étude de la syphilis et de son arsenal thérapeutique. Thèse de diplôme d’État de docteur en pharmacie, Reims, 2012, n° 4
No full textBourrinet Patrick. Guy de Maupassant : Valentin (Mathieu), À travers les Contes et Nouvelles de Guy de Maupassant, image de la pharmacie et des pharmaciens au XIXe siècle. Étude de la syphilis et de son arsenal thérapeutique. Thèse de diplôme d’État de docteur en pharmacie, Reims, 2012, n° 4. In: Revue d'histoire de la pharmacie, 99e année, N. 375, 2012. pp. 399-400
LIBS and LA-SD-OES Analysis of Minor and Trace Elements in Steel Samples
No full textAuthor Valentin Ehrentraut, BScMasterarbeit Universität Linz 2022Arbeit nach Ablauf der Sperre auf den öffentlichen PCs in den Bibliotheken der JKU+Medizin abrufba
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