50 research outputs found
On the variable hierarchy of first-order spectra
No full textThe spectrum of a first-order logic sentence is the set of natural numbers that are cardinalities of its finite models. In this paper we study the hierarchy of first-order spectra based on the number of variables. It has been conjectured that it collapses to three variable.
We show the opposite: it forms an infinite hierarchy. However, despite the fact that more variables can express more spectra, we show that to establish whether the class of first-order spectra is closed under complement, it is sufficient to consider sentences using only three variables and binary relations.The first author is supported by the Polish National Science Centre grant DEC 2012/07/D/ST6/02435. The second author is supported by FWO Pegasus Marie Curie fellowship
Creating Athletes' Image: The Impact of Social Media on Career Development in Sports Based on the Examples of C. Ronaldo, L. Messi, and R. Kubica
No full textEryk Falk - geniusz zła czy obłąkany neurastenik? ("Homo sapiens" Stanisława Przybyszewskiego)
No full textThe trilogy Homo sapiens is believed to be one of the greatest achievements of Stanisław Przybyszewski. The author of this article considered the work worthy of special attention with regard to the interesting study of a mental illness. The writer presents a self-obsessed character affected by neurosis which is the reason lor his uncontrolled behaviour. Eryk Falk suffers from neurotic disorders: he experiences hallucinations and. visions during a nervous fever. Besides, he is strongly convinced of his life mission that is, on the one hand, improving the mankind and creating geniuses while, on the other hand, destroying the world. The subject of the novel focuses on the scries of Falk’s immoral acts. Eryk commits them to calm his oversensitive, strained nerves and to release a negative, destructive energy. The author of this article thoroughly analyses the source of the main character’s insanity. It appears that his juvenile experiences and a harmful lifestyle played a considerable role in this psychical process
London is dreaming of London: culture and identity in the capital
No full textThis week’s Media Agenda Talk was about London’s identity and culture. Three panellists – Author Eve Harris, music critic Lloyd Bradley and Channel 4 Reporter Fatima Manji – presented their unique perspective on the city, stemming from their professional experience and their life as Londoners. Does London have a culture of its own, or should we be speaking of a culture of neighbourhoods? Do its inhabitants identify more as ‘Londoner’ than ‘British’? How accurately does the media represent the capital? This post was written by Polis Reporter Eryk Salvaggi
Eryk Falk – a genius of evil or an insane neurasthenic? ("Homo sapiens" by Stanisław Przybyszewski)
No full textThe trilogy Homo sapiens is believed to be one of the greatest achievements of Stanisław Przybyszewski. The author of this article considered the work worthy of special attention with regard to the interesting study of a mental illness. The writer presents a self-obsessed character affected by neurosis which is the reason for his uncontrolled behaviour. Eryk Falk suffers from neurotic disorders: he experiences hallucinations and visions during a nervous fever. Besides, he is strongly convinced of his life mission that is, on the one hand, improving the mankind and creating geniuses while, on the other hand, destroying the world.
The subject of the novel focuses on the scries of Falk’s immoral acts. Eryk commits them to calm his oversensitive, strained nerves and to release a negative, destructive energy.
The author of this article thoroughly analyses the source of the main character’s insanity. It appears that his juvenile experiences and a harmful lifestyle played a considerable role in this psychical process
Eryk Falk - a genius of evil or an insane neurasthenic? ("Homo sapiens" by Stanisław Przybyszewski)
No full textThe trilogy Homo sapiens is believed to be one of the greatest achievements of Stanisław
Przybyszewski. The author of this article considered the work worthy of special attention with
regard to the interesting study of a mental illness. The writer presents a self-obsessed character affected by neurosis which is the reason lor his uncontrolled behaviour. Eryk Falk suffers
from neurotic disorders: he experiences hallucinations and. visions during a nervous fever.
Besides, he is strongly convinced of his life mission that is, on the one hand, improving the
mankind and creating geniuses while, on the other hand, destroying the world.
The subject of the novel focuses on the scries of Falk’s immoral acts. Eryk commits them
to calm his oversensitive, strained nerves and to release a negative, destructive energy.
The author of this article thoroughly analyses the source of the main character’s insanity.
It appears that his juvenile experiences and a harmful lifestyle played a considerable role in
this psychical process.Zadanie pt. „Digitalizacja i udostępnienie w Cyfrowym Repozytorium Uniwersytetu Łódzkiego kolekcji czasopism naukowych wydawanych przez Uniwersytet Łódzki” nr 885/P-DUN/2014 dofinansowane zostało ze środków MNiSW w ramach działalności upowszechniającej nauk
Risk of prostate cancer in patients with Parkinson's disease
No full textGóralczyk Wanesa, Borowiecka Monika, Mikos Eryk, Kanon Karol. Risk of prostate cancer in patients with Parkinson’s disease. Journal of Education, Health and Sport. 2021;11(9):691-696. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2021.11.09.084
https://apcz.umk.pl/JEHS/article/view/JEHS.2021.11.09.084
https://zenodo.org/record/5533822
The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.
© The Authors 2021;
This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike.
(http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.
The authors declare that there is no conflict of interests regarding the publication of this paper.
Received: 15.09.2021. Revised: 20.09.2021. Accepted: 27.09.2021.
Risk of prostate cancer in patients with Parkinson’s disease
Wanesa Góralczyk1*, Monika Borowiecka1, Eryk Mikos1, Karol Kanon1
1Medical University of Lublin
*Corresponding author e-mail: [email protected]
Wanesa Góralczyk; ORCID: 0000-0001-5804-2869
Monika Borowiecka; ORCID: 0000-0003-2612-7838
Eryk Mikos; ORCID: 0000-0003-0507-2882
Karol Kanon; ORCID: 0000-0001-6705-1302
Abstract
Introduction: In recent years, an association between Parkinson’s disease and cancer has been reported with many clinical and epidemiological studies, encouraging the investigation of a potential common pathogenic pathway connected with both diseases. However, association between neurogenesis, medical treatment of Parkinson’s disease and occurence of prostate cancer (PCA) is still being discussed.
Brief description of the state of knowledge: There were carried out population-based case-control researches that checked the connection between Parkinson’s disease and the risk of prostate cancer in Western (Canada, USA, UK, Denmark, Sweden, Israel) and Asian (Taiwan) populations. Studies revealed that Parkinson’s disease had significant association with reduced risk of prostate cancer in most of studied populations (Western) and increased in Asian population.
Conclusions: Most of researches proved that Parkinson’s disease was associated with reduction of risk of prostate cancer, which decreased with increasing duration of Parkinson’s disease. The relationship between those conditions in Asian population needs to be checked in the future.
Key words: Parkinson’s disease, prostate cance
COLLECTION OF THE ERYK LIPIŃSKI MUSEUM OF CARICATURE IN WARSAW
No full textThe article presents the activity and the unique collection of the Eryk Lipiński Museum of Caricature in Warsaw, the sole museum in Poland which has been assembling, documenting and sharing Polish and foreign works such as cartoon art or satirical prints since 1978. The article describes the origins of the museum’s concept and its history, which are inseparably linked with the person of Eryk Lipiński, an outstanding cartoonist, draftsman and journalist. The history of the collection’s creation and how it acquired the most valuable group of exhibits is based on the analysis of archival sources. The article also describes the most valuable gifts to the museum by individual donors and institutions, as well as significant purchases by the museum itself. Prominent Polish and foreign artists whose works form part of the collection are mentioned. The collection, comprising over 25,000 works by many generations of artists active from the 18th to the 21st century and representing various artistic trends and stylistic conventions, is characterised. The article emphasises the formal diversity of the collection which, apart from the biggest collection of drawings and prints, also includes posters, paintings and sculptures. The narrative character of the museum’s collection, which documents formal changes in the art of contemporary caricature and that of the two past decades, is presented against this backdrop. Finally, the author deals with the rich collection of books and satirical magazines which complement the collection and comprise an invaluable source for research on the history of caricature and satirical prints in Poland and abroad. In conclusion, the author draws attention to the specificity of the collection of the Museum of Caricature which, together with the visual representations, also often offers verbal comments which register the transitory and changeable social and political contexts.Niniejszy artykuł prezentuje działalność oraz unikatową kolekcję Muzeum Karykatury im. Eryka Lipińskiego w Warszawie, jedynego muzeum w Polsce zajmującego się od 1978 r. gromadzeniem, dokumentowaniem i udostępnianiem polskich i zagranicznych dzieł w zakresie karykatury i rysunku satyrycznego. W artykule opisano genezę koncepcji muzeum, a także historię jego powstania, które bezpośrednio wiążą się z postacią wybitnego karykaturzysty, rysownika i publicysty Eryka Lipińskiego. Na podstawie analizy materiałów archiwalnych przedstawiono dzieje tworzenia kolekcji i pozyskiwania najważniejszych grup eksponatów. Opisano najcenniejsze dary na rzecz muzeum darczyńców indywidualnych oraz instytucji, a także znaczące zakupy dokonane przez muzeum. Wymieniono nazwiska wybitnych twórców polskich i zagranicznych, których prace znajdują się w kolekcji muzeum. Najwięcej miejsca poświęcono charakterystyce bogatej i wyjątkowej muzealnej kolekcji. Scharakteryzowany został zbiór ponad 25 000 obiektów obejmujący prace stworzone przez wiele pokoleń artystów działających od XVIII do XXI w. , reprezentujących różne nurty artystyczne i konwencje stylowe. W artykule położono nacisk na ukazanie różnorodności formalnej kolekcji, na którą, obok największego zbioru rysunków i grafik, składają się również plakaty, prace malarskie oraz rzeźba. Na tym tle przedstawiono również narracyjny charakter kolekcji muzealnej, dokumentującej zmiany formalne zachodzące w sztuce karykatury współczesnej oraz dwóch minionych wieków. Na końcu autor omówił bogaty zbiór książek i czasopism satyrycznych, które uzupełniają kolekcję muzeum i stanowią bezcenne źródło do badań nad historią karykatury i rysunku satyrycznego w Polsce i zagranicą. W podsumowaniu artykułu autor zwrócił uwagę na specyfikę zbiorów Muzeum Karykatury, które obok przedstawień plastycznych prezentują często także komentarz słowny rejestrujący ulotny i zmienny kontekst społeczno‑polityczny
Interferon alpha (IFN-α) in systemic lupus erythematosus (SLE)
No full textMOQBIL, Sara, MIKOS, Eryk, DMOCHOWSKA, Joanna, WÓJCIK, Aleksandra & LEZIAK, Milena. Interferon alpha (IFN-α) in systemic lupus erythematosus (SLE). Journal of Education, Health and Sport. 2023;13(1):56-59. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2023.13.01.008
https://apcz.umk.pl/JEHS/article/view/40149
https://zenodo.org/record/7356717
The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343.
Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences).
Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159.
Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu).
© The Authors 2022;
This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike.
(http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.
The authors declare that there is no conflict of interests regarding the publication of this paper.
Received: 22.09.2022. Revised: 20.11.2022. Accepted: 23.11.2022.
Interferon alpha (IFN-α) in systemic lupus erythematosus (SLE)
Sara Moqbil, Eryk Mikos, Joanna Dmochowska, Aleksandra Wójcik, Milena Leziak
Medical University of Lublin
Corresponding author: Sara Moqbil, [email protected]
Sara Moqbil: https://orcid.org/0000-0003-1230-1444, [email protected]
Eryk Mikos: https://orcid.org/0000-0003-0507-2882, [email protected]
Joanna Dmochowska, https://orcid.org/0000-0003-0396-2363, [email protected]
Aleksandra Wójcik, https://orcid.org/0000-0003-1669-7466, [email protected]
Milena Leziak https://orcid.org/0000-0001-9911-5534, [email protected]
Abstract:
Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown etiology. An important role in the pathogenesis of SLE has been attributed to interferon alpha (IFN-α), which stimulates the expression of numerous genes, resulting in an increased autoinflammatory response. Recent studies have demonstrated increased levels of this cytokine in patients with SLE, as well as in relatives, indicating that IFN- α is an inherited risk factor for lupus. Cases of induction of SLE/lupus-like syndrome after IFN- α therapy also point to the involvement of interferon in the pathogenesis of the disease. Interferon being a probable initiator of the disease, as well as a marker to examine its exacerbations, is a potential research target to better understand the etiology and pathogenesis of lupus. More research is needed to determine the feasibility of using INF-blocking agents for new therapies in SLE.
Keywords: systemic lupus erythematosus, interferon alpha, IFN-α-induced SL
Non-invasive diagnostic methods for fatal familial insomnia
No full textMikos Eryk, Moqbil Sara, Dmochowska Joanna, Wasyluk Martyna, Góralczyk Wanesa. Non-invasive diagnostic methods for fatal familial insomnia. Journal of Education, Health and Sport. 2022;12(7):616-619. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2022.12.07.061
https://apcz.umk.pl/JEHS/article/view/JEHS.2022.12.07.061
https://zenodo.org/record/6892896
The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343.
Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences).
Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159.
Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu).
© The Authors 2022;
This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike.
(http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.
The authors declare that there is no conflict of interests regarding the publication of this paper.
Received: 10.07.2022. Revised: 17.07.2022. Accepted: 24.07.2022.
Non-invasive diagnostic methods for fatal familial insomnia
Nieinwazyjne metody diagnostyczne śmiertelnej dziedzicznej bezsenności
Eryk Mikos, Sara Moqbil, Joanna Dmochowska, Martyna Wasyluk, Wanesa Góralczyk
Uniwersytet Medyczny w Lublinie
Corresponding author: Eryk Mikos, [email protected]
ORCID ID and e-mail:
Eryk Mikos https://orcid.org/0000-0003-0507-2882, [email protected]
Sara Moqbil https://orcid.org/0000-0003-1230-1444, [email protected]
Joanna Dmochowska https://orcid.org/0000-0003-0396-2363, [email protected]
Martyna Wasyluk https://orcid.org/0000-0001-5897-7568, [email protected]
Wanesa Góralczyk https://orcid.org/0000-0001-5804-2869, [email protected]
Abstract
Fatal familial insomia (FFI) is a dominant autosomal genetic prion disease characterised by progressive sleep impairment, autonomic nervous system disorders and motor symptoms associated with significant loss of nerve cells in the medial thalamic nuclei.
Making a diagnosis of FFI requires the presence of a certain or probable recognised first-degree relative of the patient, together with neuropsychiatric disorders present. In turn, the detection of the PrP mutation allows the diagnosis to be definitively established. In addition, three other tests - polysomnography, brain imaging and cerebrospinal fluid examination - can be helpful.
Fatal familial insomnia is not a fully understood disease. Diagnosis is based on the presence of symptoms of the disease. An important step in diagnosis will be the development of non-invasive diagnostic tests that are reliable in the early and presymptomatic stages of the disease. Polysomnography, imaging studies (PET, SPECT) and cerebrospinal fluid examination should be improved and widely accepted.
Keywords: fatal familial insomnia; diagnostic methods; polysomnography; imaging tests; cerebrospinal fluid biomarkers
Abstrakt
Śmiertelna dziedziczna bezsenność (FFI) jest dominującą autosomalną genetyczną chorobą prionową charakteryzującą się postępującym upośledzeniem snu, zaburzeniami autonomicznego układu nerwowego i objawami ruchowymi związanymi ze znaczną utratą komórek nerwowych w jądrach przyśrodkowych wzgórza.
Postawienie diagnozy FFI wymaga obecności pewnego lub prawdopodobnego rozpoznanego krewnego pierwszego stopnia pacjenta wraz z obecnymi zaburzeniami neuropsychiatrycznymi. Z kolei wykrycie mutacji PrP pozwala na ostateczne ustalenie rozpoznania. Dodatkowo pomocne mogą być trzy inne badania – polisomnografia, obrazowanie mózgu i badanie płynu mózgowo-rdzeniowego.
Śmiertelna dziedziczna bezsenność nie jest w pełni poznaną chorobą. Diagnoza opiera się na obecności objawów choroby. Ważnym krokiem w diagnostyce będzie opracowanie nieinwazyjnych testów diagnostycznych, które są niezawodne we wczesnych i przedobjawowych stadiach choroby. Polisomnografia, badania obrazowe (PET, SPECT) i badanie płynu mózgowo-rdzeniowego powinny zostać ulepszone i powszechnie akceptowane.
Słowa kluczowe: śmiertelna dziedziczna bezsenność; metody diagnostyczne; polisomnografia; badania obrazowe; biomarkery płynu mózgowo-rdzenioweg
