52,486 research outputs found
Treatment of Lion´s Mane jellyfish stings-
Treatment of Lion´s Mane jellyfish stings- hot water immersion versus topical corticosteroids
Student: Anna Nordesjö Supervisor: Kai Knudsen
In Sweden, contact with the Lion’s Mane jellyfish Cyanea capillata is not uncommon during the summer months, with subsequent local symptoms such as pain and itching, which may persist for several hours.
Several remedies for jellyfish stings, such as urine, vinegar and baking soda are described in numerous websites and in the literature, most of them citing limited or no scientific evidence. Hot-water immersion is a popular treatment for many marine stings and has recently been found to reduce local pain following stings from certain species of jellyfish. Topical corticosteroids are recommended as symptomatic treatment for jellyfish stings by the Swedish Poisons Information Centre (Giftinformationscentralen), but the effect has not yet been researched.
The objective of this study is to evaluate treatment with cortisone cream compared to hot water immersion (HWI) for reducing local symptoms such as pain and itching. The study was carried out as a clinical trial including 20 healthy human test subjects who were exposed to the tentacles of Cyanea capillata on each foot and then treated with HWI on one foot and a topical corticosteroid on the other. The results suggest that HWI is slightly more effective for treating acute pain and itch than cortisone up to 6 h after treatment with p-values <0.05, and after 24 hours there was basically no remaining symptoms.
This study increases the evidence for HWI treatment, which is a safe and accessible method and should therefore be further communicated to the public.
The second part of this study was a laboratory trial and investigated whether various substances recommended for treatment of local symptoms did fire the nematocysts, jellyfish stinging cells. The results suggest that vinegar does cause the nematocysts to fire and should therefore not be used for treatment of stings from this particular species
Acute Effects of Naturally Occurring Guayusa Tea and Nordic Lion’s Mane Extracts on Cognitive Performance
The aim of this study was to assess the effects of guayusa extract and Nordic Lion’s Mane (LM) on cognition. Using a randomized, double-blind, placebo-controlled, crossover design, we examined the effects of a single dose of 650 mg guayusa extract (AMT: AmaTea® Max) vs. 1 g Nordic-grown Lion’s Mane (LM) vs. placebo (PL). Participants attended three testing visits consisting of neuropsychological tests (Go/No-go, N-Back, and Serial 7 s tasks) assessing performance, subjective assessments of cognitive perception, and vital signs. Each assessment was measured at baseline (pre-ingestion) and 1 and 2 h post ingestion. AMT significantly (p ≤ 0.05) improved the number of attempts during Serial 7s, total score, number of correct responses, total number of responses, and reaction time during N-Back and improved Go stimulus reaction time, but it reduced the percentage of correct responses in the No-go stimulus response during Go/No-go. LM significantly (p ≤ 0.05) improved the number of attempts during Serial 7s and reaction time during N-Back and improved Go stimulus reaction time in Go/No-go. AMT improved mental clarity, focus, concentration, mood, and productivity at 1 and 2 h (p < 0.05); the ability to tolerate stress at 1 h; and had greater ratings than LM and PL for mental clarity, focus, concentration, and productivity. PL improved focus and concentration at 1 h from baseline (p ≤ 0.05). AMT and LM improved subjective ratings of “happiness compared to peers” and “getting the most out of everything” (p < 0.05); however, this occurred earlier in LM (i.e., 1 h post ingestion). AMT uniquely elevated blood pressure from baseline. AMT significantly improved cognitive performance and self-perceived cognitive indices of affect over a 2 h period and perceptions of happiness 2 h post ingestion. In comparison, LM helped improve working memory, complex attention, and reaction time 2 h post ingestion and perceptions of happiness over a 2 h period
Experimental investigation of plasma impedance in Linac4 source
CERN ’s new particle accelerator Linac4 is part of the upgrade of the LHC accelerator chain. Linac4 is required to deliver 160 MeV H− beam to improve the beam brightness and luminosity in the Large Hadron Collider (LHC). The Linac4 H− source must deliver 40-50 mA, 45 keV H− beam in the RFQ acceptance. Since the RF power coupled to the H− source plasma is one of the important parameters that determines the quality of the H− beam, the experimental investigation of the dependence of the load impedance on the operational parameters is mandatory. In this study, we have measured the impedance of the H− source plasma varying the RF power coupled to the plasma and the condition of the hydrogen gas. Also, optical emission spectroscopy (OES) measurements have been carried out simultaneously with the impedance measurement in order to determine the plasma parameters. The determination of the plasma parameters allows us to compare the experimental results with the analytic model of the plasma parameters, which is useful to discuss the results from a physical point of view
Influence of the cusp field on the plasma parameters of the Linac4 H− ion source
When the H ion source of CERN’s Linac4 is operated in volume mode, a maximum of the extracted current is obtained at varying RF power. The power required for this maximum and its absolute value is strongly influenced by the cusp magnets installed at the source for electron confinement: without magnets, 15−20 mA are typically obtained at 20 kW whereas with magnets a factor of two more power is needed and 25−30 mA are achieved. In order to access the reasons behind the peaked performance with varying RF power and for determining the influence of the cusp field on the discharge, optical emission spectroscopy (OES) measurements of the atomic Balmer series and of the molecular Fulcher transition have been carried out. In all investigated cases, the gas temperature of the discharge has been virtually equal to the ambient temperature as the short discharge pulse length of 500 s is not long enough for considerable heavy particle heating. When no cusp magnets are installed, the plasma parameters evaluated with the collisional radiative models Yacora H and Yacora H show a minimum in the electron temperature of 3.25 eV and a maximum in the electron density of and also in the vibrational excitation of the hydrogen molecule at 20 kW. Assessing the relevant production and destruction processes demonstrates that the H yield is maximal at this point thereby explaining the optimum ion source performance. When the cusp magnets are applied, the same general trends are observed but the required RF power is a factor of two higher. The OES results indicate an optimum performance around 30 kW whereas the highest H current is actually achieved around 40 kW. Furthermore, a higher H yield is indicated without cusp magnets but a better ion source performance is observed with magnets. These differences can most likely be attributed to changing gradients in the plasma parameters which are not accessible by OES. Nevertheless, the obtained plasma parameters can be used as benchmark for RF coupling codes simulating the Linac4 ion source
A molecular dynamics study of N-A-S-H gel with various Si/Al ratios
The understanding of sodium aluminosilicate hydrate (N-A-S-H) gel is still limited due to its complex and amorphous structure. Recently, molecular dynamics simulation has provided a unique opportunity to better understand the structure of N-A-S-H gel from nanoscale. In this work, the N-A-S-H gel structure was obtained by simulating the polymerization of Si and Al monomers by molecular dynamics. The simulated polymerization process is in good agreement with the experimental results especially in terms of the reaction rate of Si and Al species. The atomic structural features of the N-A-S-H gel were analyzed in terms of bond length and bond angle information, simulated X-ray diffraction (XRD) and Qn distribution. A significant finding is the existence of pentacoordinate Al in all simulated N-A-S-H structures, indicating that pentacoordinate Al in geopolymer does not only come from raw material. Besides, the results show that a smaller Si/Al ratio led to a more crosslinked and compacted structure of N-A-S-H gel
The construction of Karen Karnak: The multi-author-function
This thesis is situated within the comparatively recent developments of Web 2.0 and the emergence of interactive WikiMedia, and explores the mode of authorship within a Read/Write culture compared to that of a Read/Only tradition. The hypothesis of this study is that the role of the audience has become merged with the author, and as such, represents new functions and attributes, distinct from a more conventional concept of authorship, in which the roles of audience and author are more separate. Read/Write and participatory culture, as defined by this study, is focused on collaboration, and includes the influences of D.I.Y. culture, Open-Source practices and the production of text by multiple authors. Multi-authorship presents a re-thinking of several concepts which support the notion of the individual author, since the focus of multi-authorship is not on attribution and ownership of a finished text, but on the continued malleability of a text. Modes of multi-authorship, demonstrated in the use of the pseudonyms Alan Smithee and Karen Eliot, represent declarative authors whose names signify multiple origins, whilst concurrently indicating a distinct body of work. The function of these names form an important context to this study, since primary research involves the construction of an experimental mode of multi-authorship utilising WikiMedia technology and the interaction of thirty nine participants, who are invited to create a body of work under the collective pseudonym Karen Karnak. The data generated by this experiment is analysed using aspects of Michel Foucault's author-function to identify and determine power structures inherent in the WikiMedia context. The interplay of power structures, including concepts such as identity, ownership and the body of work, affect the resulting mode of authorship and contribute to the construction of Karen Karnak, suggesting further areas of research into the emerging multi-author
Effects of the extraction voltage applied by the puller-electrode on the H extraction in the Linac4 negative ion source
In order to understand the H extraction mechanism and investigate the effect of the extraction voltage applied by the puller-electrode on the H extraction in the Linac4 negative ion source, we are developing a 2D3V-PIC (two dimensions in the real space and three dimensions in the velocity space, Particle in Cell) model with volume produced H ions. It is shown that how to take the magnetic filter field direction is important for the 2D modeling to take into account the important 3D effect of electron drift. It is also shown that the meniscus formation is not symmetric due to the electron drift in the extraction region and the divergence of the H beam is asymmetric. In order to make more quantitative comparison of the extracted H and electron currents with the experiments and 3D modeling, further improvements, especially the electron loss along the magnetic filter field line will be needed
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Measuring industry-science links through inventor-author relations: A profiling method
In this pilot study we examine the performance of text-based profiling in recovering a set of validated inventor-author links. In a first step we match patents and publications solely based on their similarity in content. Next, we compare inventor and author names on the highest ranked matches for the occurrence of name matches. Finally, we compare these candidate matches with the names listed in a validated set of inventor-author names. Our text-based profile methodology performs significantly better than a random matching of patents and publications, suggesting that text-based profiling is a valuable complementary tool to the name searches used in previous studies.innovation; industry-science links; text-based profiling;
Influence of Alternating Magnetic Field on Growth and Polysaccharide outside the Cell of Lions mane hericium
作者简介: 高梦祥,副教授,博士,主要从事磁致微生物效应、农产品物理保鲜方法研究,E-mail : mxgao0398 @yahoo. com. cn[中文文摘]以猴头菌为研究对象,通过改变磁场强度和作用时间,研究交变磁场对猴头菌生长效应的影响。试验结果表明:磁场对猴头菌胞外多糖的作用相对菌丝的作用有滞后性,在磁场强度为1.06 A/m,作用时间为12 h时,磁场对猴头菌菌丝的生长促进作用最强,猴头菌的菌质干质量增长率达140.1%;作用时间为24 h时,猴头菌胞外多糖质量浓度增长率达100.8%;作用时间为48 h时,磁场对猴头菌胞外多糖的生长促进作用最强,猴头菌胞外多糖质量浓度增长率达271.7%。在作用时间为24 h时,磁场对猴头菌胞外多糖的生长促进作用最强的磁场强度为0.8 A/m,猴头菌胞外多糖质量浓度增长率达187.5%。[英文文摘]The stimulation of alternating magnetic field on L ions mane herici um was studied by using a self2
designed generator with adjustable magnetic field intensity and time. The result s showed that the effect s of the magnetic field on the growth of L ions mane herici umps hypha have the sluggish functioning of the produce of polysaccharide out side the cell. When the intensity of the magnetic field is 1106 A/ m , time is 12 h , the dry weight of the L ions mane herici um increased 14011 %. The concent ration of the L ions mane herici umps polysaccharide increased 27117 % when the intensity of the magnetic field is 1106 A/ m , time is 24 h. The concent ration of the L ions mane herici umps
polysaccharide increased 27117 % when the intensity of the magnetic field is 1106 A/ m , time is 48 h ,which is the st rongest stimulation of the L ions mane herici umps polysaccharide.湖北省教育厅重点科研资助项目(B200512002); 长江大学博士启动基金资助项目(03000282
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