1,549 research outputs found
Artful living and the eradication of worry in Søren Kierkegaard's interpretation of Matthew 6:24-34
No full textDanish thinker Søren Kierkegaard published fourteen discourses, across four collections, on Matthew 6:24-34. The repeated readings of the biblical text, whose themes include the choice between God and mammon, worry, what it means to consider the birds and lilies, and how to seek first the kingdom of God, converge with Kierkegaard’s interest in anxiety, despair, worry, subjectivity, indirect communication, choice, the moment, and life before God. Accordingly, the discourses make connections with his larger works, elucidate frequently explored Kierkegaardian themes in recent scholarship, and contribute to his critique of nineteenth-century Copenhagen. Additionally, the collections present an interpretation of each verse and phrase of Matthew’s text and, held up against modern Matthew scholarship, they correlate with and contribute to Sermon on the Mount and New Testament studies. Kierkegaard’s reading of Matthew also holds implications for the practice of biblical interpretation as it promotes the importance of awareness of sin, interestedness, and appropriation as central to proper reading. His emphasis on Christ as the primary exemplar of Matthew’s text adds an additional Christological element to his hermeneutic. Furthermore, the discourses serve as spiritual treatises which provide the reader with theological terminology to help confront the problem of worry and suffering. In light of a human being’s distinctiveness as imago Dei, Kierkegaard elucidates ways an individual may respond artfully to the ongoing possibility of worry, a possibility which the discourses connect with Christian anthropology and external labels associated with possessions and status. The Matthew 6 discourses intimate Kierkegaard’s sympathy with classic Christian spirituality and, in combination with the cultural-ecclesiastical critique, the creative exegesis, and the in-depth analysis of the cause of and cure for worry, his work emerges as an excellent example of spiritual theology
Matthew’s Emmanuel Messiah: a paradigm of presence for god's people
No full textThe motif of divine presence is a clear phenomenon within the Gospel of Matthew. The modern critical means for assessing the ancient biblical text have multiplied to the point, some claim, of disparity. This study employs both narrative and redaction criticism in an attempt to respond authentically to the structural, historical and theological dimensions of Matthew's Gospel. This study begins with the presumption of the wholeness and integrity of Matthew's narrative, and assumes the gospel story to have an inherently dramatic structure which invites readers to inhabit imaginatively its narrative world and respond to its call. But since we are concerned with the role of both reader and author, this study also assumes a text with an historical author and context. The introduction focuses on the meta-critical dilemma facing New Testament students - what is the text and how do we read it? - and seeks some balance in terms of Krieger's analogy of the text as both window and mirror. Proposed is a narrative reading of Matthew's presence motif alongside a redaction critical assessment of it. In Chapter 2 the elements of narrative theory are introduced and relevant terms defined: the structure of narrative, the function of the narrator, points of view. Chapter 3 becomes an exercise in narrative reading, with Matthew's presence motif providing the focus, and the implied reader’s interaction with the story being predominant in interpretation. Characters, rhetorical devices, and points of view are discussed, to understand the motif's development throughout the story's progress. The thrust of Chapter 4 is thereafter to examine divine presence as a dominant motif within Matthew's most important literary context: the Jewish scriptures. Here the primary paradigms of divine presence provided by the Patriarchs, the Sinai experience, and the Davidic-Zion traditions are assessed. Chapter 5 follows with a more detailed examination of the OT "I am with you/God is with us" formula and its µeo' vµwv/ηuwv language, so strongly connected to Matthew's presence motif. Chapters 6-8 build on these investigations with a closer analysis of the three critical "presence passages" of Mt 1:23. 18:20 and 28:20. The passages and their contexts are probed from a redaction critical perspective, guided by the narrative investigation of Chapter 3, and the background from Chapters 4 and 5.The three major "presence passages" examined in Chapters 6-8 are also complimented by a number of secondary issues: worship, wisdom, the Spirit and the poor in Matthew, and their relation to Jesus' divine presence. These are discussed in Chapter 9. Chapter 10 summarizes and looks briefly at some implications. Matthew' presence motif proves to be an important element of the Gospel’s rhetorical design, redactional strategy and Christology. The presence of Jesus, the Emmanuel Messiah, exhibited in his risen authority, becomes the focus of his people's hopes and experiences in the post-Easter world. What the presence of Yahweh was to his people. Jesus now provides in a new paradigm for his people - his followers, the little ones, the poor and the marginalized, from all nations
Adapting Bach's Goldberg Variations for the Organ
No full textabstract: This creative project provides an adaptation of J. S. Bach’s Goldberg Variations, BWV 988, for the Fritts Organ at Arizona State University. This organ was designed and built by Paul Fritts and Co. in 1992, and is in the style of the high-Baroque instruments of Northern Europe. Along with the musical score of the adaptation, this document discusses the registration choices included as well as relevant historical and performance practice details about the piece. A link to the recording of the author’s April 2017 performance of this edition of the Goldberg Variations on the ASU Fritts Organ is included with the project.Dissertation/ThesisDoctoral Dissertation Music 201
sj-xlsx-2-ajr-10.1177_19458924221134732 - Supplemental material for RNA Sequencing and Gene Ontology Analysis in Acute Invasive Fungal Sinusitis
No full textSupplemental material, sj-xlsx-2-ajr-10.1177_19458924221134732 for RNA Sequencing and Gene Ontology Analysis in Acute Invasive Fungal Sinusitis by Abel P. David, Patricia A. Loftus, Matthew S. Russell, Andrew N. Goldberg, Ivan H. El-Sayed, Taha A. Jan and Lauren T. Roland in American Journal of Rhinology & Allergy</p
sj-xlsx-1-ajr-10.1177_19458924221134732 - Supplemental material for RNA Sequencing and Gene Ontology Analysis in Acute Invasive Fungal Sinusitis
No full textSupplemental material, sj-xlsx-1-ajr-10.1177_19458924221134732 for RNA Sequencing and Gene Ontology Analysis in Acute Invasive Fungal Sinusitis by Abel P. David, Patricia A. Loftus, Matthew S. Russell, Andrew N. Goldberg, Ivan H. El-Sayed, Taha A. Jan and Lauren T. Roland in American Journal of Rhinology & Allergy</p
Alliance and psychological distress RI-CLPM
No full textThis registration provides data, analysis code, and materials associated with the following publication: Goldberg, S. B., Jiwani, Z., Bolt, D. M., Riordan, K. M., Davidson, R. J., & Hirshberg, M. J. (in press). Evidence for bidirectional, cross-lagged associations between alliance and psychological distress in an unguided mobile health intervention. Clinical Psychological Science
Bilateral and unilateral arm training improve motor function through differing neuroplastic mechanisms: a single-blinded randomized controlled trial
No full textBACKGROUND AND PURPOSE:
This randomized controlled trial tests the efficacy of bilateral arm training with rhythmic auditory cueing (BATRAC) versus dose-matched therapeutic exercises (DMTEs) on upper-extremity (UE) function in stroke survivors and uses functional magnetic resonance imaging (fMRI) to examine effects on cortical reorganization.
METHODS:
A total of 111 adults with chronic UE paresis were randomized to 6 weeks (3×/week) of BATRAC or DMTE. Primary end points of UE assessments of Fugl-Meyer UE Test (FM) and modified Wolf Motor Function Test Time (WT) were performed 6 weeks prior to and at baseline, after training, and 4 months later. Pretraining and posttraining, fMRI for UE movement was evaluated in 17 BATRAC and 21 DMTE participants.
RESULTS:
The improvements in UE function (BATRAC: FM Δ = 1.1 + 0.5, P = .03; WT Δ = -2.6 + 0.8, P < .00; DMTE: FM Δ = 1.9 + 0.4, P < .00; WT Δ = -1.6 + 0.7; P = .04) were comparable between groups and retained after 4 months. Satisfaction was higher after BATRAC than DMTE (P = .003). BATRAC led to significantly higher increase in activation in ipsilesional precentral, anterior cingulate and postcentral gyri, and supplementary motor area and contralesional superior frontal gyrus (P < .05). Activation change in the latter was correlated with improvement in the WMFT (P = .01).
CONCLUSIONS:
BATRAC is not superior to DMTE, but both rehabilitation programs durably improve motor function for individuals with chronic UE hemiparesis and with varied deficit severity. Adaptations in brain activation are greater after BATRAC than DMTE, suggesting that given similar benefits to motor function, these therapies operate through different mechanisms
Study of K* production in tau decay
No full textcomplete author list:
Goldberg M.; Haupt T.; Horwitz N.; Jain V.; Mestayer M.; Moneti G.; Rozen Y.; Rubin P.; Sharma V.; Skwarnicki T.; Thulasidas M.; Zhu G.; Csorna S.; Letson T.; Alexander J.; Artuso M.; Bebek C.; Berkelman K.; Browder T.; Cassel D.; Cheu E.; Coffman D.; Crawford G.; DeWire J.; Drell P.; Ehrlich R.; Galik R.; Garcia-Sciveres M.; Geiser B.; Gittelman B.; Gray S.; Halling A.; Hartill D.; Heltsley B.; Honscheid K.; Kandaswamy J.; Katayama N.; Kreinick D.; Lewis J.; Ludwig G.; Masui J.; Mistry N.; Mevissen J.; Nandi S.; Nordberg E.; O'Grady C.; Peterson D.; Pisharody M.; Riley D.; Sapper M.; Selen M.; Silverman A.; Stone S.; Worden H.; Worris M.; Sadoff A.; Avery P.; Besson D.; Garren L.; Yelton J.; Kinoshita K.; Pipkin F.; Procario M.; Wilson R.; Wolinski J.; Xiao D.; Zhu Y.; Ammar R.; Baringer P.; Coppage D.; Haas P.; Kwak N.; Lam H.; Ro S.; Kubota Y.; Nelson J.; Perticone D.; Poling R.; Fulton R.; Jensen T.; Johnson D.; Kagan H.; Kass R.; Morrow F.; Whitmore J.; Wilson P.; Bortoletto D.; Chen W.; Dominick J.; McIlwain R.; Miller D.; Ng C.; Schaffner S.; Shibata E.; Shipsey I.; Yao W.; Sparks K.; Thorndike E.; Wang C.; Alam M.; Kim I.; Li W.; Romero V.; Sun C.; Wang P.; Zoeller M.; Goldberg M.; Zoeller M.; Goldberg M
Behavioral, Neurochemical, and Histological Characterization of Mice Deficient for Parkin, DJ-1, and Antioxidant Proteins
No full textParkinson’s disease is a progressive neurodegenerative disease characterized by a loss of dopaminergic neurons in the substantia nigra. The cause of Parkinson’s disease remains uncertain, however, evidence implicates mitochondrial dysfunction and oxidative stress with selective vulnerability of dopaminergic neurons. Although most cases of Parkinson’s disease are sporadic, 5-10% of cases are caused by mutations in a single gene. Loss-of-function mutations in parkin and DJ-1 were the first to be linked to recessively inherited parkinsonism. Surprisingly, mice bearing similar loss-of-function mutations in parkin and DJ-1 do not show age-dependent loss of nigral dopaminergic neurons or depletion of dopamine in the striatum. Although the normal cellular functions of Parkin and DJ-1 remain unclear, we hypothesized that Parkin and DJ-1 protect cells from oxidative stress and that loss-of-function mutations in these genes cause neurodegeneration in Parkinson’s disease by rendering cells more sensitive to mitochondrial dysfunction and oxidative stress. We crossed mice deficient for Parkin and DJ-1 with mice deficient for the major mitochondrial antioxidant protein Mn-superoxide dismutase or Cu/Zn-superoxide dismutase. Previous studies have shown that mice with reduced levels of Cu/Zn-superoxide dismutase or Mn-superoxide dismutase are more sensitive to dopaminergic neurotoxins whereas mice with increased levels of superoxide dismutase are more resistant to dopaminergic neurotoxins. We predicted that reducing levels of antioxidant proteins in parkin-/-DJ-1-/- mice would result in age-dependent nigral cell loss, striatal dopamine depletion or behavioral abnormalities. Characterization of these mice for behavioral abnormalities, neurotransmitter defects and neuropathology, revealed significant behavioral abnormalities in the mutant mice even in the absence of significant changes to dopamine levels in the striatum, dopamine receptor density, or dopaminergic neuron numbers. Aged parkin-/-DJ-1-/- and Mn-superoxide dismutase triple deficient mice have a surprising enhanced rotorod performance without the presence of an anxiety phenotype or hyperactivity. Cu/Zn-superoxide dismutase and Mn-superoxide dismutase triple deficient mice have elevated levels of dopamine in the striatum, however none of the mice present with nigral cell loss. Levels of D1-like and D2-like dopamine receptors in the striatum were unchanged. It is evident from our studies that on a parkin/DJ-1 null background, additional loss of major antioxidant proteins does not lead to a progressive loss of dopaminergic neurons in mice
The importance of pairwork in educational and interdisciplinary initiatives
No full textAn early and prominent employee of Google, Georges Harik, recently made the assertion that pairs working together in startups are 20 times more productive than individuals working alone. The author has also personally experienced the boost of what is here termed pairwork in a university setting during the startup phase of several educational and interdisciplinary initiatives. The paper briefly explores pairwork in the history of technology and constructs both qualitative and little quantitative models of pairwork. The quantitative model under reasonable assumptions easily recovers Harik’s 20x boost. The paper also briefly examines the author’s recent experiences with pairwork in four interdisciplinary and educational initiatives
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