831 research outputs found
La ricognizione critica di Paolo Merlo: Una replica
No full textThe article is a response to Paolo Merlo’s critique of A. Fumagalli’s book, L’amore possibile. Persone omosessuali e morale cristiana. After carefully examining the reasons adopted by Merlo to demonstrate the fragility and insufficiency of the arguments put forward in the book in favor of the ethical legitimacy – within certain limits – of homosexual love, their inconsistency is brought to light and thus the inadequacy of the examination made by the author in his critique of the book.L’articolo è una risposta alla ricognizione critica di Paolo Merlo al libro di A. Fumagalli, L’amore possibile. Persone omosessuali e morale cristiana. Va-gliando puntualmente le ragioni addotte per dimostrare la fragilità e l’insuf-ficienza delle argomentazioni presentate nel libro in favore della legittimità etica – a determinate condizioni – dell’amore omosessuale, si mette in luce la loro inconsistenza e, di conseguenza, l’inadeguatezza della critica condotta dall’Autore della ricognizione sul libro
Assessment of average muscle fiber conduction velocity from surface EMG signals during fatiguing dynamic contractions
No full textNon solo albi illustrati per i più piccoli. Quando la letteratura promuove immaginazione
No full textIl presente contributo intende affrontare una riflessione in merito alla necessità di accompagnare i piccoli lettori, ma non solo, al gusto della pagina scritta. una riflessione che si fa tanto più urgente oggi di fronte alla diffusa proposta di albi illustrati di eccezionale raffinatezza, con i quali i piccoli lettori si confrontano sin dalla più tenere età. il valore di queste produzioni non è assolutamente messo in discussione, tuttavia si vuole porre l'attenzione sulla necessità di non rendere esclusiva questa proposta, ossia sull'opportunità di permettere il confronto con la pagina scritta, con le righe nere sulla pagina bianca direbbe Calvino e sul potenziale immaginativo che quelle righe contengono. cos'è l'immaginazione, quale il suo rapporto con la parola scritta, quale il valore pedagogico dell'immaginazione sono alcuni punti sui quali cercheremo di riflettere, attraverso alcuni esempi di letture di grandi autori che hanno rivolto la loro attenzione verso i più piccoli. This paper intends to deal with the urgency of introducing young ones (and no only) to approciate reading. This question is, at present, more relevant than in the past because to children are offerd more and more, richer and richer picture-books. The author does not depreciate these narrative products, but wishes to address her attention to the fact that this kind of storytelling must not be exsclusive and must be (or ought to be) accompanied by ordinary books so to stimulate, with their black written lines, children imagination with potential educational implications. Amd, what is imagination? Which in the relation between written words and imagination? What is the educational meaning of imagination? These are the main thems of this paper, which considers some outstanding authors of children literature and their meaningful titles
Le strutture interne tra Sei e Settecento
No full textThe article focuses on the history of some functional buildings inside the Venetian fortification known as "Castello" in Brescia. After the construction of the new bastions finally designed in 1588, Venetian government started to build other necessary structures to make the new fortress operative: barracks, a military hospital, barns, armories, gunpowder depot, mills and water cisterns. Through the analysis of cartography and written primary sources, the author dates the exact construction of these buildings and infrastructures, some of which are still existing, while other has been demolished
Le edizioni documentarie varesine di Luisa Zagni: spunti per nuove ricerche.
No full textIl contributo è incentrato sulla documentazione della basilica di San Vittore di Varese degli anni 899-1289 edita in tre volumi da Luisa Zagni. L’analisi dei 710 documenti pubblicati ha consentito di tracciare a grandi linee la storia del notariato locale e di individuare tra i notai che lavorano per l’ente nella seconda metà del secolo XIII alcuni notai-chierici.
The contribution focuses on the documentation of the basilica of San Vittore in Varese during the years 899-1289 and published in three volumes by Luisa Zagni. The analysis of 710 published documents has allowed the author to trace in outline the history of the local notary and to identify some clerics who work among the notaries for the institution in the second half of the thirteenth century
Formas de reconhecimento existentes em trabalhadores da CAGE e a relação com a saúde mental
No full textEsta dissertação de caráter investigativo discute o reconhecimento na CAGE (Controladoria Geral do Estado) relacionando o mesmo com a saúde mental dos trabalhadores. Aponta para as formas de reconhecimento formal e informal que os trabalhadores encontram no ambiente de trabalho. Utiliza o recurso da entrevista como método, ressaltando o carater analítico das falas. Estas são analisadas através de eixos tematicos escolhidos que emergem das falas dos servidores e de sua abordagem frente as questões referentes ao reconhecimento trazidas pela pesquisadora. Utiliza na discussão a relação prazer/sofrimento no trabalho e prossegue apresentando as formas de reconhecimento. Classifica os seguintes eixos temáticos: cargo, remuneração, cursos oferecidos, ambiente fisico, relações sócio-profissionais, autoridade da função e conhecimento. Associa todos estes itens à saúde mental e física dos trabalhadores. O principal autor utilizado é Christophe Dejours e os autores da escola brasileira da Psicodinâmica do Trabalho como Álvaro Merlo e Ana Magnólia Mendes. Estes que pesquisam e trazem a teoria francesa para a realidade brasileira. Conclui apontando como os trabalhadores lidam com a presença ou ausência de reconhecimento e ainda como encontram formas para que o obtenham em seu trabalho. Embora os trabalhadores digam que o reconhecimento pode não existir, e que não haja clareza destes trabalhadores nas formas encontradas pela pesquisa, o reconhecimento se constitui em um tema que desperta interesse e estimula a fala dos entrevistados. Evidencia-se que o mesmo é fundamental nas relações de trabalho e pode ocorrer nos espaços públicos e nas relações entre chefias e trabalhadores.This investigative study discusses recognition on CAGE relating it to workers’ mental health. It shows the formal and informal recognition that workers encounter at their workplace. It used interviews as a method, highlighting the analytical chracter of the speeches. They are analyzed through chosen theme axes that arise from workers’ speeches and their approach to the issues concerning recognition brought up by the researcher. The relationship between pleasure and suffering at work is analyzed in the study and forms of recognition are presented. It classifies the following theme axes: position, earnings, courses offered, physical environment, emotional environment, authority of function and knowledge. It associates all these items to the workers’ physical and mental health. The main author used is Christophe Dejours, as well as authors from the Brazilian School of Psychodynamics of Work, such as Álvaro Merlo and Ana Magnólia Mendes. These authors research and bring the French theory to the Brazilian reality. The study concludes by pointing out how workers deal with the presence or absence of recognition, as well as how they find ways to obtain it at their jobs. Although workers claim that recognition might not exist and that workers are not clear enough in the study, recognition is a subject of interest and encourages the interviewees’ speech. It is evident that recognition is essential for relationships at work and may occur in public spaces and the relationships between a boss and a worker
Distributed Storage for the Provision of Ancillary Services to the Main Grid: Project PRESTO
No full textAbstractThis paper presents the three-year PRESTO research project (2013-2015). PRESTO is a self-funded project developed by the Department of Energy of Politecnico di Milano in cooperation with FIAMM Storage, Elvi Energy and MCM Energy Lab (an Italian spin-off). Within the project, experimental tests and numerical simulations were performed in order to evaluate the effectiveness of an Energy Storage System (ESS) in the provision of ancillary services to the main grid. This paper focuses specifically on the experimental and numerical analyses carried out in the project to develop an innovative control law for the primary frequency regulation, able to maximize the performances of the regulating service and effectively manage the ESS state of charge
The role of the Bmi1-GSK3β pathway in glioblastoma
No full textMalignant gliomas remain one of the deadliest of all cancers despite maximal
therapy. They present unique challenges to therapy with a median survival of 12 months.
Simultaneous activation of several growth promoting and anti-apoptotic pathways
represents the basis for the failure of monotherapies against this disease. In order to
efficiently block growth of glioblastoma (GBM) cells, we have applied several
combinatorial approaches. We have found that combination of histone deactylase
inhibitors along with the glycolytic inhibitor 2-deoxyglucose (2DG) efficiently induced
apoptosis in GBM cells. Furthermore, combination of the microtubule inhibitor
patupilone and AEE788 –an inhibitor of EGFR, which is frequently activated in gliomas,
induced apoptosis in GBM cells at doses that as single drugs were not effective. In GBM
and other cancers, subpopulations of tumor cells with stem cell properties that are
believed to constitute a tumor cell reservoir, have been identified. GBM cells frequently
express the progenitor cell markers Nestin and Sox2 and low levels of the differentiation
markers CNPase, GFAP and !-tubulin III. Bmi1 and Glycogen synthase kinase 3 (GSK3)
has been implicated in stem cell maintenance, but how Bmi1 regulates differentiation is
still unknown. We have identified a link between Bmi1 and GSK3 and showed that
blocking GSK3 may be instrumental to reduce the GBM cancer stem cell pool. We found
that the GSK3 inhibitors SB216763 as well as Lithium chloride depleted the cancer stem
cell population in GBM cells and induced tumor cell differentiation, irrespective of the
CD133 status. Cell proliferation and colony formation were markedly reduced in a dosedependent
manner.
Future work giving a deeper insight into the regulatory mechanisms of the
receptor tyrosine kinases and downstream effectors will help us to identify more specific
targets. Understanding the mechanisms why some targeted therapies work and others fail
will finally bring us to the level that efficient long-term treatment strategies can be
envisaged
Integrating the New Brand into the After-service Process of Swecon AS
No full textKäesolevas lõputöös uuriti ja kirjeldati Merlo kui uue kaubamärgi tulekut ettevõttesse AS Swecon, mis tegeleb ehitusmasinate müügi ja järelteenindusega. Swecon AS-il puudus mitme brändi juhtimise kogemus, sest eelnevalt on ettevõte esindanud vaid ühte kaubamärki. Lõputöös selgitati välja Merlo tehase nõudeid, tingimusi ja mõju, mida edasimüüja peab suutma järgima klientide ees uue toote esindamisel.
Töö autor võttis oma uurimistöös vaatluse alla ettevõtte poolt uue esindatava kaubamärgina kasutusele võetava masina müügieelsel perioodil tehtud ja paratamatusena kaasas käiva kuluarvutuse, mis sisuliselt jääb edasimüüja kanda. Uurimistöö kätkes täiendavate investeeringutega seotud kulusid, mis on seotud tootevalmistaja poolt seatud protseduurireeglite ja erinevate nõuete järgimisega, mida peab edasimüüja müügieelselt järgima.
Lõputöös käsitleti uue kaubamärgi esindamisega lisanduvad tööülesanded ja nende jagunemise olemasolevate töötajate vahel. Töö autor andis edasi teiste ettevõtete kogemused uue toote juurutamisega seotud väljakutsetest ja sellele järgnevast kohandusmisprotsessist ning tavapäraseks tööprotsessiks muutumisest.
Töö käigus loodi Merlo laomasinatele ülevaatuse põhjad, mis on olulised abivahendid masinate kvaliteedi ja toimivuse tagamisel ning rutiini loomisel, et masin vaadatakse üle kord nädalas. Ülevaatuse lehe eesmärk on tagada, et masinad oleksid klientidele esitlemiseks valmis ja töökorras. Kuna äril on oluline kasumit teenida, siis koostati vastavad arvutused Merlo ning Volvo ülevaatuse kohta ning analüüsiti neid. Tuginedes uuringu tulemustele, tegi autor järeldused uue kaubamärgi integreerimise ja sellega seonduvate vajalike tegevuste kohta ning esitas Swecon AS’ile ettepanekuid Merlo brändi sujuvaks integreerimiseks järelteeninduse protsessi.This thesis investigated and described the arrival of Merlo as a new brand in the company AS Swecon, which deals with the sale and after-sales service of construction machinery. Swecon AS lacked the experience of managing multiple brands, as the company previously represented only one brand. In the thesis, the requirements, conditions, and effects of the Merlo factory were identified, which the distributor must be able to follow when representing the new product in front of the customers.
In the research, the author took into consideration the cost calculation made by the company in the pre-sale period of the machine introduced as a new representative brand, and which inevitably goes along with it, which essentially remains the responsibility of the dealer. The research contained costs related to additional investments related to compliance with procedural rules set by the product manufacturer and various requirements that the dealer must follow before the sale.
The thesis discussed the duties added to the representation of the new brand and their distribution among the existing employees. The author of the paper conveyed the experiences of other companies about the challenges associated with the introduction of a new product and the subsequent adaptation process and the transition to a normal work process.
During the work, inspection bases were created for Merlo warehouse machines, which are important aids in ensuring the quality and performance of the machines and creating a routine that the machine is inspected once a week. The purpose of the inspection sheet is to ensure that the machines are ready and in working order for presentation to customers. Since it is important for the business to make a profit, the corresponding calculations for the inspection of Merlo and Volvo were prepared and analyzed. Based on the results of the study, the author made conclusions about the integration of the new brand and the necessary activities related to it and presented proposals to Swecon AS for the smooth integration of the Merlo brand into the after-service process
Indicazione delle fabbriche, chiese, e pitture di Verona, o sia, Guida per li forestieri.
No full textIncludes indexes.Plan of Verona dated 1756 and signed "Urbani" by the engraver (Angelo Urbani?). View of the Verona ampitheater.Perhaps by Giuseppe Marini, author of Indicazione delle chiese pitture e fabbriche della città di Verona (Verona : Erede Merlo, 1797).Mode of access: Internet
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