738 research outputs found
A novel loss of function FLAD1 variant, causing riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency (MADD)
No full textDisgust sensitivity relates to attitudes toward gay men and lesbian women across 31 nations
No full textvan Leeuwen, F.; Inbar, Y.; Petersen, M. B.; Aaroe, L.; Barclay, P.; Barlow, F. K.; de Barra, M.; Becker, D. V.; Borovoi, L.; Choi, J.; Consedine, N. S.; Conway, J. R.; Conway, P.; Adoric, V. C.; Demirci, E., Fernández, A. M., Seco-Ferreira, D. C., Ishii, K., Jakšić, I., Ji, T., Jonaityte, I., Lewis, D. M. G., Li, N. P., McIntyre, J. C., Mukherjee, S. Park, J. H., Pawlowski, B., Pizarro, D., Prokop, P., Prodromitis, G. Rantala, M. J., Reynolds, M. J., Sandin, B., Sevi, B., Srinivasan, N., Tewari, S., Yong, J. C., Zezelj, I., & Tybur, J. M.</p
Thickness of hydroxyapatite nanocrystal controls mechanical properties of the collagen-hydroxyapatite interface.
No full textsj-docx-1-gpi-10.1177_13684302211067151 – Supplemental material for Disgust sensitivity relates to attitudes toward gay men and lesbian women across 31 nations
No full textSupplemental material, sj-docx-1-gpi-10.1177_13684302211067151 for Disgust sensitivity relates to attitudes toward gay men and lesbian women across 31 nations by Florian van Leeuwen, Yoel Inbar, Michael Bang Petersen, Lene Aarøe, Pat Barclay, Fiona Kate Barlow, Mícheál de Barra, D. Vaughn Becker, Leah Borovoi, Jongan Choi, Nathan S. Consedine, Jane Rebecca Conway, Paul Conway, Vera Cubela Adoric, Ekin Demirci, Ana María Fernández, Diogo Conque Seco Ferreira, Keiko Ishii, Ivana Jakšić, Tingting Ji, Inga Jonaityte, David M. G. Lewis, Norman P. Li, Jason C. McIntyre, Sumitava Mukherjee, Justin H. Park, Boguslaw Pawlowski, David Pizarro, Pavol Prokop, Gerasimos Prodromitis, Markus J. Rantala, Lisa M. Reynolds, Bonifacio Sandin, Barış Sevi, Narayanan Srinivasan, Shruti Tewari, Jose C. Yong, Iris Žeželj and Joshua M. Tybur in Group Processes & Intergroup Relations</p
Everyday Stepping Quantity and Quality Among Older Adult Fallers With and Without Mild Cognitive Impairment: Initial Evidence for New Motor Markers of Cognitive Deficits?
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Exercise induced bronchospasm and chlorine in swimming pools
No full textIncludes bibliographical references (leaves 47-57).The purpose of this thesis was firstly to review the possible relationship between chlorine in swimming pool water and exercise induced bronchospasm, and secondly to assess whether chlorine exposure during swimming provokes EIB in well-trained swimmers with and without a history of EIB
Magnetic resonance-guided focused ultrasound for patients with painful bone metastases: phase III trial results.
No full textPain due to bone metastases is a common cause of cancer-related morbidity, with few options available for patients refractory to medical therapies and who do not respond to radiation therapy. This study assessed the safety and efficacy of magnetic resonance-guided focused ultrasound surgery (MRgFUS), a noninvasive method of thermal tissue ablation for palliation of pain due to bone metastases. Patients with painful bone metastases were randomly assigned 3:1 to receive MRgFUS sonication or placebo. The primary endpoint was improvement in self-reported pain score without increase of pain medication 3 months after treatment and was analyzed by Fisher's exact test. Components of the response composite, Numerical Rating Scale for pain (NRS) and morphine equivalent daily dose intake, were analyzed by t test and Wilcoxon rank-sum test, respectively. Brief Pain Inventory (BPI-QoL), a measure of functional interference of pain on quality of life, was compared between MRgFUS and placebo by t test. Statistical tests were two-sided. One hundred forty-seven subjects were enrolled, with 112 and 35 randomly assigned to MRgFUS and placebo treatments, respectively. Response rate for the primary endpoint was 64.3% in the MRgFUS arm and 20.0% in the placebo arm (P < .001). MRgFUS was also superior to placebo at 3 months on the secondary endpoints assessing worst score NRS (P < .001) and the BPI-QoL (P < .001). The most common treatment-related adverse event (AE) was sonication pain, which occurred in 32.1% of MRgFUS patients. Two patients had pathological fractures, one patient had third-degree skin burn, and one patient suffered from neuropathy. Overall 60.3% of all AEs resolved on the treatment day. This multicenter phase III trial demonstrated that MRgFUS is a safe and effective, noninvasive treatment for alleviating pain resulting from bone metastases in patients that have failed standard treatments. © The Author 2014. Published by Oxford University Press
Ornamental plants: a summary of research, 1990
No full textPhysical facilities and capital requirements for establishing a three-acre perennial container nursery in Ohio -1989 / Reed D. Taylor, Elton M. Smith, George P. Pealer -- Production costs of operating a three-acre perennial container nursery in Ohio - 1989 / Reed D. Taylor, Elton M. Smith, George P. Pealer -- Comparative costs of producing alternative plants in a three-acre perennial container nursery in Ohio – 1989 / Reed D. Taylor, Elton M. Smith, George P. Pealer -- Marketing and sales strategies practiced by Ohio nurseries / Reed D. Taylor, Elton M. Smith, W. Timothy Rhodus -- Evaluation of flowering crabapple susceptibility to apple scab in Ohio - 1989 / Elton M. Smith and Sharon A. Treaster -- Fertilizing trees in the landscape: an 18-year evaluation / Elton M. Smith and Sharon A. Treaster -- The influence of irrigation water temperature upon leaf abscision in Ficus benjamina and Dracaena marginata / Julia A. O’Bryan and John C. Peterson -- A two-year tolerance study of narcissus cultivars to selected pre-emergence herbicides / Elton M. Smith and Sharon A. Treaster -- Tolerance of clematis and wisteria to Ronstar and Devrinol / Elton M. Smith and Sharon A. Treaster -- Increasing efficiency of slow-release herbicide tablets / Elton M. Smith and Sharon A. Treaster -- Developing biorational pesticides for the landscape industry / David G. Nielsen -- Interactions between subdue and slow-release fertilizers at high temperatures / Y. Inbar, H. A. J. Hoitink, M. E. Watson, K. D. Cochran, E. M. Smith -- Evaluation of powdery mildew severity on deciduous azaleas at the Secrest Arboretum - 1989 / Kenneth D. Cochran and C. Wayne Ellett -- Winter damage, regrowth and vigor of old garden roses / Gary A. Anderso
Assessing the Performance of Bamboo Structural Components
No full textBamboo has been a traditional construction material in many regions for centuries. The rapid growth and maturation rate of bamboo as well as its good strength properties and global accessibility make it a promising non-conventional building material resource. However, due to limited standardization and design criteria, bamboo has often been relegated to non-engineered and marginally-engineered construction. The current study assesses the performance of full-culm structural bamboo components and appropriate standard material and member test methods. A brief overview is given to the motivation for the study of structural bamboo, placing the work in its social context, followed by background on the properties of bamboo and the structural applications of the material as well as the pathway to its further standardization and utilization. Experimental and analytical studies are conducted focusing on the tensile, flexural, buckling, and environmental sustainability performance of full-culm bamboo components. Standard bamboo tension tests are carried out to investigate the test interferences associated with the functionally graded fiber distribution across the culm wall thickness. Tension specimens oriented in both the radial and tangential directions are considered in order to isolate the effects of the fiber gradation both on test results and experimental methodology. Recognizing longitudinal splitting induced by flexure as a dominant limit state, modified standard bamboo flexural tests are performed to investigate the development of a standard test procedure for this limit state, which involves a mixed-mode longitudinal splitting failure in the flexural element. Flexural testing considers two test configurations and three difference species of bamboo. Results of modified full-culm tests are compared with smaller clear bamboo flexural specimens taken from the culm wall as well as standard or proposed tests for pure mode I and pure mode II failure components. The experimental buckling capacity of single-culm and multiple-culm bamboo columns is studied as further understanding of column strength is critical to the construction of more robust and potentially multiple-story bamboo structures. Finally, in an effort to quantify the perceived sustainability benefits of bamboo, the environmental impacts of multiple-culm bamboo columns are compared with structurally comparable timber and steel alternatives in a comparative midpoint life cycle analysis
Associations between daily-living physical activity and laboratory-based assessments of motor severity in patients with falls and Parkinson's disease
No full textINTRODUCTION: Recent work suggests that wearables can augment conventional measures of Parkinson's disease (PD). We evaluated the relationship between conventional measures of disease and motor severity (e.g., MDS-UPDRS part III), laboratory-based measures of gait and balance, and daily-living physical activity measures in patients with PD. METHODS: Data from 125 patients (age: 71.7 ± 6.5 years, Hoehn and Yahr: 1-3, 60.5% men) were analyzed. The MDS-UPDRS-part III was used as the gold standard of motor symptom severity. Gait and balance were quantified in the laboratory. Daily-living gait and physical activity metrics were extracted from an accelerometer worn on the lower back for 7 days. RESULTS: In multivariate analyses, daily-living physical activity and gait metrics, laboratory-based balance, demographics and subject characteristics together explained 46% of the variance in MDS-UPDRS-part III scores. Daily-living measures accounted for 62% of the explained variance, laboratory measures 30%, and demographics and subject characteristics 7% of the explained variance. Conversely, demographics and subject characteristics, laboratory-based measures of gait symmetry, and motor symptom severity together explained less than 30% of the variance in total daily-living physical activity. MDS-UPDRS-part III scores accounted for 13% of the explained variance, i.e., <4% of all the variance in total daily-living activity. CONCLUSIONS: Our findings suggest that conventional measures of motor symptom severity do not strongly reflect daily-living activity and that daily-living measures apparently provide important information that is not captured in a conventional one-time, laboratory assessment of gait, balance or the MDS-UPDRS. To provide a more complete evaluation, wearable devices should be considered.sponsorship: We thank the study participants and all of those who contributed to the V-TIME project. This work was funded in part by a grant from the European Commission. (European Commission)status: Publishe
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